Publikasi Scopus 2025 per tanggal 31 Januari 2025 (67 artikel)

Objective: Water plays a crucial role in human health. Inadequate water intake can lead to various health issues, particularly dehydration in the elderly. The skin, constituting approximately 30.0% of the body's surface area, is essential in preventing dehydration, and water contributes significantly to its resilience, elasticity, and durability. This study aimed to establish a definitive relationship between fluid intake and various biophysical properties of the stratum corneum in elderly Individuals. Methods: This cross-sectional study was conducted on individuals aged 65-80 years at the Elderly Social Institution Tresna Budi Mulia 3 in Jakarta, between April and August 2023. Correlation analysis (Pearson and Spearman tests) was used to evaluate relationships between variables, and non-parametric tests (Mann-Whitney and Friedman tests) were used to assess differences. Fluid intake was assessed over 7 days. On the 8th day, the hydration status of the stratum corneum was evaluated by examining their urine concentration, skin dryness through subjective symptoms, skin water loss based on the rate of water evaporation from the skin, and skin capacitance (SCap) according to the skin's ability to retain moisture. Results: The study involved 67 subjects with a median age of 70 years. Multiple regression analysis showed that fluid intake significantly predicted the specified symptom sum score (SRRC) (coefficient = -9.15 × 105, P = 0.001), urine specific gravity (coefficient = -0.01, P = 0.016), and SCap (coefficient = 0.005, P = 0.022). Additionally, a statistically significant weak negative correlation was found between fluid intake and hydration status (P < 0.0001) and between fluid intake and SRRC (P < 0.0001). However, no significant correlation was observed between fluid intake and transepidermal water loss (P = 0.613) or SCap (P = 0.060). Conclusion: This study highlights the potential role of fluid intake in influencing hydration status among elderly individuals. While fluid intake is significantly associated with certain biophysical properties of the skin, it does not show a consistent correlation with all measures of skin hydration and moisture retention. Copyright © 2025 Hospital for Skin Diseases (Institute of Dermatology), Chinese Academy of Medical Sciences, and Chinese Medical Association, published by Wolters Kluwer, Inc.