Husna, F., Department of Pharmacology, Faculty of Medicine, Syiah Kuala University, Aceh, Indonesia; Suyatna, F.D., Department of Pharmacology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Arozal, W., Department of Pharmacology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Purwaningsih, E.H., Department of Pharmacology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Hanafi, M., Research Center of Chemistry, National Research and Innovation Agency (BRIN), Serpong, Indonesia; Razali, R., Department of Physiology, Faculty of Medicine, Universitas Syiah Kuala, Aceh, Indonesia; Asrizal, C.W., Department of Physiology, Faculty of Medicine, Universitas Syiah Kuala, Aceh, Indonesia