Publikasi Scopus 2010 s/d 2022

Introduction: The presence of atypical squamous cells of undetermined significance (ASCUS) from pap smear result should be followed by cytology follow-up, HPV DNA testing, or colposcopy, as there is a possibility of progress to cervical cancer. This study aims to evaluate the frequency of distinct HPV genotypes and colposcopy findings among women with ASCUS cytology results. Methods: A descriptive study in 846 women was conducted in Dr. Cipto Mangunkusumo General Hospital using retrospective data between 2016 and 2018. Of 124 patients with ASCUS cytology results, all had HPV DNA examinations, but only 63 had colposcopy examinations. Participants who were married, sexually active, and willing to participate were included. Patients with incomplete data were excluded. The data were processed using Statistical Product and Service Solutions (SPSS) version 25.0. Results: The incidence of ASCUS in the population was 14.7%. Among 124 subjects with ASCUS, 47 (37.9%) had a high-risk HPV infection. From 63 ASCUS women who underwent colposcopy, 27 subjects (42.8%) were normal. Type 52 of HPV showed the most frequent genotype appearing, especially within 30–50 years of age. Conclusion: 42.8% of the colposcopy findings for women with ASCUS were normal, and 37.9% of ASCUS women had a high-risk HPV infection. Type 52 was found to be the most frequent genotype that appears in ASCUS patients in Indonesia. © 2022, The Author(s) under exclusive licence to Association of Gynecologic Oncologists of India.