Publikasi Scopus 2010 s/d 2022

Authors_(Last_Name)

Wong D., Matini L., Kormilitzin A., Kantschuster R., Simadibrata D.M., Lyden S., Wilson J., Brain O.A., Palmer R., Ambrose T., Satsangi J., South M., Geddes J., Bodger K., Travis S.P.L., Walsh A.

Author S Id

57222537226;57191724696;21834209900;57222539087;57202134322;58123802400;57220919993;26530922100;32867960100;36623184100;7006615924;25646985400;56883972800;6701335993;23483262600;22936329300;

Title

Patient-reported Outcomes: the ICHOM Standard Set for Inflammatory Bowel Disease in Real-life Practice Helps Quantify Deficits in Current Care

Year

2022

Source Title

Journal of Crohn's and Colitis

Volume

Issue

Art No

Page Start

1874

Page End

1881

Page Count

Cited By

Link

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85149184882&doi=10.1093%2fecco-jcc%2fjjac099&partnerID=40&md5=82cd9e1d3224d94406f57962d173f999

Affiliations

Translational Gastroenterology Unit, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, NIHR Biomedical Research Centre, Oxford, OX3 9DU, United Kingdom; Department of Gastroenterology, Austin Health, Heidelberg, VIC, Australia; Department of Psychiatry, University of Oxford, Oxford, United Kingdom; Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Health Data Science, Institute of Population Health, University of Liverpool, Liverpool, United Kingdom

Authors With Affiliations

Wong, D., Translational Gastroenterology Unit, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, NIHR Biomedical Research Centre, Oxford, OX3 9DU, United Kingdom, Department of Gastroenterology, Austin Health, Heidelberg, VIC, Australia; Matini, L., Translational Gastroenterology Unit, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, NIHR Biomedical Research Centre, Oxford, OX3 9DU, United Kingdom; Kormilitzin, A., Department of Psychiatry, University of Oxford, Oxford, United Kingdom; Kantschuster, R., Translational Gastroenterology Unit, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, NIHR Biomedical Research Centre, Oxford, OX3 9DU, United Kingdom; Simadibrata, D.M., Translational Gastroenterology Unit, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, NIHR Biomedical Research Centre, Oxford, OX3 9DU, United Kingdom, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Lyden, S., Translational Gastroenterology Unit, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, NIHR Biomedical Research Centre, Oxford, OX3 9DU, United Kingdom; Wilson, J., Translational Gastroenterology Unit, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, NIHR Biomedical Research Centre, Oxford, OX3 9DU, United Kingdom; Brain, O.A., Translational Gastroenterology Unit, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, NIHR Biomedical Research Centre, Oxford, OX3 9DU, United Kingdom; Palmer, R., Translational Gastroenterology Unit, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, NIHR Biomedical Research Centre, Oxford, OX3 9DU, United Kingdom; Ambrose, T., Translational Gastroenterology Unit, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, NIHR Biomedical Research Centre, Oxford, OX3 9DU, United Kingdom; Satsangi, J., Translational Gastroenterology Unit, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, NIHR Biomedical Research Centre, Oxford, OX3 9DU, United Kingdom; South, M., Department of Psychiatry, University of Oxford, Oxford, United Kingdom; Geddes, J., Translational Gastroenterology Unit, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, NIHR Biomedical Research Centre, Oxford, OX3 9DU, United Kingdom; Bodger, K., Department of Health Data Science, Institute of Population Health, University of Liverpool, Liverpool, United Kingdom; Travis, S.P.L., Translational Gastroenterology Unit, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, NIHR Biomedical Research Centre, Oxford, OX3 9DU, United Kingdom; Walsh, A., Translational Gastroenterology Unit, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, NIHR Biomedical Research Centre, Oxford, OX3 9DU, United Kingdom

Abstract

Background: Patient-reported outcome measures [PROMs] are key to documenting outcomes that matter most to patients and are increasingly important to commissioners of health care seeking value. We report the first series of the ICHOM Standard Set for Inflammatory Bowel Disease [IBD]. Methods: Patients treated for ulcerative colitis [UC] or Crohn's disease [CD] in our centre were offered enrolment into the web-based TrueColours-IBD programme. Through this programme, e-mail prompts linking to validated questionnaires were sent for symptoms, quality of life, and ICHOM IBD outcomes. Results: The first 1299 consecutive patients enrolled [779 UC, 520 CD] were studied with median 270 days of follow-up (interquartile range [IQR] 116, 504). 671 [52%] were female, mean age 42 years (standard deviation [sd] 16), mean body mass index [BMI] 26 [sd 5.3]. At registration, 483 [37%] were using advanced therapies. Median adherence to fortnightly quality of life reporting and quarterly outcomes was 100% [IQR 48, 100%] and 100% [IQR 75, 100%], respectively. In the previous 12 months, prednisolone use was reported by 229 [29%] patients with UC vs 81 [16%] with CD, p<0.001; 202 [16%] for<3 months; and 108 [8%] for>3 months. An IBD-related intervention was reported by 174 [13%] patients, and 80 [6%] reported an unplanned hospital admission. There were high rates of fatigue [50%] and mood disturbance [23%]. Conclusions: Outcomes reported by patients illustrate the scale of the therapeutic deficit in current care. Proof of principle is demonstrated that PROM data can be collected continuously with little burden on health care professionals. This may become a metric for quality improvement programmes or to compare outcomes. © 2022 The Author(s). Published by Oxford University Press on behalf of European Crohn's and Colitis Organisation.

Author Keywords

ICHOM; Inflammatory bowel disease; patient reported outcomes

Index Keywords

adult; age distribution; Article; body mass; controlled study; Crohn disease; disease activity; disease burden; disease severity; fatigue; female; follow up; help seeking behavior; hospital admission; human; major clinical study; male; mood disorder; observational study; outcome assessment; patient-reported outcome; prospective study; quality of life; sex difference; ulcerative colitis; university hospital; chronic disease; Crohn disease; inflammatory bowel disease; patient-reported outcome; ulcerative colitis; Adult; Chronic Disease; Colitis, Ulcerative; Crohn Disease; Female; Humans; Inflammatory Bowel Diseases; Male; Patient Reported Outcome Measures; Quality of Life

Funding Details

Funding Text 1

Funding Text 2

Funding Text 3

Publisher

Oxford University Press

Issn

18739946

Isbn

Pubmed Id

35868223

Document Type

Article

Sjr Best Quartile

Sjr

2429

Sjr Rank

884