Publikasi Scopus 2010 s/d 2022

Authors_(Last_Name)

Muharam R., Prasetyo Y.D., Prabowo K.A., Putri Y.I., Maidarti M., Hestiantoro A.

Author S Id

57191492732;57685883000;57224859187;57687701600;56320510400;8743255100;

Title

IVF outcome with a high level of AMH: a focus on PCOS versus non-PCOS

Year

2022

Source Title

BMC Women's Health

Volume

Issue

Art No

172

Page Start

Page End

Page Count

Cited By

Link

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85130066042&doi=10.1186%2fs12905-022-01756-4&partnerID=40&md5=4bc5566deb68a12d4edf1abdc2025d0d

Affiliations

Division of Reproductive Immunoendocrinology, Department of Obstetrics & Gynecology, Faculty of Medicine, University of Indonesia–Cipto Mangunkusumo National Hospital, Jl. Pangeran Diponegoro No.71, Kenari, Kec. Senen, Kota Jakarta Pusat, Daerah Khusus Ibukota Jakarta, 10430, Indonesia; Department of Obstetrics and Gynecology, Faculty of Medicine, University of Indonesia–Cipto Mangunkusumo National Hospital, Jl. Pangeran Diponegoro No.71, Kenari, Kec. Senen, Kota Jakarta Pusat, Daerah Khusus Ibukota Jakarta, 10430, Indonesia

Authors With Affiliations

Muharam, R., Division of Reproductive Immunoendocrinology, Department of Obstetrics & Gynecology, Faculty of Medicine, University of Indonesia–Cipto Mangunkusumo National Hospital, Jl. Pangeran Diponegoro No.71, Kenari, Kec. Senen, Kota Jakarta Pusat, Daerah Khusus Ibukota Jakarta, 10430, Indonesia; Prasetyo, Y.D., Department of Obstetrics and Gynecology, Faculty of Medicine, University of Indonesia–Cipto Mangunkusumo National Hospital, Jl. Pangeran Diponegoro No.71, Kenari, Kec. Senen, Kota Jakarta Pusat, Daerah Khusus Ibukota Jakarta, 10430, Indonesia; Prabowo, K.A., Division of Reproductive Immunoendocrinology, Department of Obstetrics & Gynecology, Faculty of Medicine, University of Indonesia–Cipto Mangunkusumo National Hospital, Jl. Pangeran Diponegoro No.71, Kenari, Kec. Senen, Kota Jakarta Pusat, Daerah Khusus Ibukota Jakarta, 10430, Indonesia; Putri, Y.I., Division of Reproductive Immunoendocrinology, Department of Obstetrics & Gynecology, Faculty of Medicine, University of Indonesia–Cipto Mangunkusumo National Hospital, Jl. Pangeran Diponegoro No.71, Kenari, Kec. Senen, Kota Jakarta Pusat, Daerah Khusus Ibukota Jakarta, 10430, Indonesia; Maidarti, M., Division of Reproductive Immunoendocrinology, Department of Obstetrics & Gynecology, Faculty of Medicine, University of Indonesia–Cipto Mangunkusumo National Hospital, Jl. Pangeran Diponegoro No.71, Kenari, Kec. Senen, Kota Jakarta Pusat, Daerah Khusus Ibukota Jakarta, 10430, Indonesia; Hestiantoro, A., Division of Reproductive Immunoendocrinology, Department of Obstetrics & Gynecology, Faculty of Medicine, University of Indonesia–Cipto Mangunkusumo National Hospital, Jl. Pangeran Diponegoro No.71, Kenari, Kec. Senen, Kota Jakarta Pusat, Daerah Khusus Ibukota Jakarta, 10430, Indonesia

Abstract

Background: The purpose of this research was to investigate whether high AMH levels in PCOS patients resulted in different IVF outcomes compared to those in non-PCOS patients. Methods: A retrospective cohort study was conducted involving 238 women undergoing IVF who had AMH levels > 4 ng/ml. Participants were divided into two groups: PCOS and non-PCOS. Results: The median AMH level was significantly higher in the PCOS group (7.59 ± 4.61 ng/ml vs. 5.91 ± 2.22 ng/ml, p < 0.001). The PCOS group required less gonadotropin but yielded more oocytes after stimulation. Significantly more participants from the PCOS group (41.5% [n = 39]) developed a hyperresponse to ovarian stimulation compared to the non-PCOS group (26.4% [n = 38]) (OR = 1.978, 95% CI 1.138–3.488; p = 0.015). Conclusion: There were significant differences in terms of total doses of gonadotropin and the number of oocytes retrieved in the PCOS and non-PCOS groups. Women with PCOS and high AMH levels have a higher risk of hyperresponse after ovarian stimulation than women without PCOS. © 2022, The Author(s).

Author Keywords

Index Keywords

cetrorelix; choriogonadotropin alfa (drug); gonadotropin; Muellerian inhibiting factor; progesterone; recombinant follitropin; Muellerian inhibiting factor; adult; Article; cohort analysis; controlled ovarian stimulation; controlled study; disease severity; female; female infertility; hormone blood level; human; in vitro fertilization; infertility therapy; major clinical study; oocyte number; ovary hyperstimulation; ovary polycystic disease; predictive value; receiver operating characteristic; retrospective study; sensitivity and specificity; treatment outcome; complication; in vitro fertilization; procedures; Anti-Mullerian Hormone; Female; Fertilization in Vitro; Gonadotropins; Humans; Polycystic Ovary Syndrome; Retrospective Studies

Funding Details

Funding Text 1

Funding Text 2

Funding Text 3

Publisher

BioMed Central Ltd

Issn

14726874

Isbn

Pubmed Id

35568864

Document Type

Article

Sjr Best Quartile

Sjr

742

Sjr Rank

6335