No records
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38 |
Dhelika R., Hadi A.F., Yusuf P.A. |
55536628000;57368046500;57192156597; |
Development of a motorized hospital bed with swerve drive modules for holonomic mobility |
2021 |
Applied Sciences (Switzerland) |
11 |
23 |
1356 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85120877522&doi=10.3390%2fapp112311356&partnerID=40&md5=7c16eb6fe630116772c69c4d02b4bd9f |
Department of Mechanical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI, Depok, 16424, Indonesia; Department of Medical Physics/Medical Technology Core Cluster IMERI, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia |
Dhelika, R., Department of Mechanical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI, Depok, 16424, Indonesia; Hadi, A.F., Department of Mechanical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI, Depok, 16424, Indonesia; Yusuf, P.A., Department of Medical Physics/Medical Technology Core Cluster IMERI, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia |
In hospitals; transferring patients using hospital beds is time consuming and inefficient. Additionally; the task of frequently pushing and pulling beds poses physical injury risks to nurses and caregivers. Motorized hospital beds with holonomic mobility have been previously proposed. However; most such beds come with complex drivetrain which makes them costly and hinders largerāscale adoption in hospitals. In this study; a motorized hospital bed that utilizes a swerve drive mechanism is proposed. The design takes into account simplicity which would allow for minimum modification of the existing beds. Two DC motors for steering and propulsion are used for a single swerve drive module. The control of the propulsion motor is achieved by a combination of trajectory planning based on quintic polynomials and PID control. Further; the control performance of the proposed bed was evaluated; and the holonomic mobility of its prototype was successfully demonstrated. An average error of less than 3% was obtained for motion with a constant velocity; however; larger values in the range of 15% were observed for other conditions, such as accelerating and decelerating. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
Hospital bed; Mechatronics; PID control; Swerve drive; Trajectory planning |
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MDPI |
20763417 |
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Article |
Q2 |
435 |
11324 |
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99 |
Herawati F., Yulia R., Wiyono H., Massey F.K., Muliani N., Kantono K., Soemantri D., Andrajati R. |
57194722742;56768083700;57321279000;57321051400;57222261946;56580346400;36640659100;9940247700; |
Discordance to ashp therapeutic guidelines increases the risk of surgical site infection |
2021 |
Pharmaceuticals |
14 |
11 |
1088 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118387727&doi=10.3390%2fph14111088&partnerID=40&md5=f3621ba3decf103d84295afa3e55e549 |
Department of Clinical and Community Pharmacy, Faculty of Pharmacy, Universitas Surabaya, Surabaya, 60293, Indonesia; Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Indonesia, Depok, 16424, Indonesia; Faculty of Medicine, Universitas Surabaya, Surabaya, 60293, Indonesia; Department of Food Science, Auckland University of Technology, Private Bag 92006, Auckland, 1142, New Zealand; Department of Medical Education, Faculty of Medicine, Universitas Indonesia, Depok, 16424, Indonesia |
Herawati, F., Department of Clinical and Community Pharmacy, Faculty of Pharmacy, Universitas Surabaya, Surabaya, 60293, Indonesia, Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Indonesia, Depok, 16424, Indonesia; Yulia, R., Department of Clinical and Community Pharmacy, Faculty of Pharmacy, Universitas Surabaya, Surabaya, 60293, Indonesia; Wiyono, H., Faculty of Medicine, Universitas Surabaya, Surabaya, 60293, Indonesia; Massey, F.K., Department of Clinical and Community Pharmacy, Faculty of Pharmacy, Universitas Surabaya, Surabaya, 60293, Indonesia; Muliani, N., Department of Clinical and Community Pharmacy, Faculty of Pharmacy, Universitas Surabaya, Surabaya, 60293, Indonesia; Kantono, K., Department of Food Science, Auckland University of Technology, Private Bag 92006, Auckland, 1142, New Zealand; Soemantri, D., Department of Medical Education, Faculty of Medicine, Universitas Indonesia, Depok, 16424, Indonesia; Andrajati, R., Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Indonesia, Depok, 16424, Indonesia |
Clean surgery without contamination does not require prophylactic antibiotics, but there are high-risk surgical procedures that may cause infection and/or involve vital organs such as the heart, brain, and lungs, and these indeed require the use of antibiotics. This study aimed to determine the quantity of antibiotic use based on the defined daily dose (DDD) per 100 bed days and the quality of antibiotic use based on the percentage of concordance with The American Society of Health-System Pharmacists (ASHP) therapeutic guidelines (i.e., route of administration, time of administration, selection, dose, and duration). This includes the profiles of surgical site infection (SSI) in surgical patients from January through June 2019. The study subjects were 487 surgical patients from two hospitals who met the inclusion criteria. There were 322 patients out of 487 patients who had a clean surgical procedure. Ceftriaxone (J01DD04) was the most used antibiotic, with a total DDD/100 bed days value in hospitals A and B, respectively: pre-surgery: 14.71, 77.65, during surgery: 22.57, 87.31, and postsurgery: 38.34, 93.65. In addition, 35% of antibiotics were given more than 120 min before incision. The lowest concordance to ASHP therapeutic guideline in hospital A (17.6%) and B (1.9%) was antibiotic selection. Two patients experienced SSI with bacterial growths of Proteus spp., Staphylococcus aureus, Staphylococcus epidermidis, and Escherichia coli. The usage of prophylactic antibiotics for surgical procedures was high and varied between hospitals. Hospital B had significantly lower concordance to antibiotic therapeutic guidelines, resulting to a higher infection rate, compared with hospital A. ASHP adherence components were then further investigated, after which antibiotic dosing interval and injection time was found to be a significant predictor for positive bacterial growth based on logit–logistic regression. Further interventions and strategies to implement antibiotic stewardship is needed to improve antibiotic prescriptions and their use. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
Antibiotic stewardship; Defined daily dose; Hospital; Surgical site infection |
amoxicillin; amoxicillin plus clavulanic acid; ampicillin; antibiotic agent; beta lactamase inhibitor; cefadroxil; cefazolin; cefepime; cefixime; cefoperazone; cefotaxime; cefoxitin; ceftazidime; ceftriaxone; chloramphenicol; ciprofloxacin; clindamycin; cotrimoxazole; fosfomycin; gentamicin; levofloxacin; meropenem; metronidazole; moxifloxacin; norfloxacin; ofloxacin; oxacillin; sulbactam; sultamicillin; tetracycline; vancomycin; adult; aged; antibiotic sensitivity; antimicrobial stewardship; Article; bacterial growth; bacterium culture; drug choice; drug use; Escherichia coli; female; human; infection rate; infection risk; intraoperative period; length of stay; major clinical study; male; medical society; middle aged; observational study; postoperative period; practice guideline; preopera |
MDPI |
14248247 |
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Article |
Q1 |
1295 |
2918 |
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150 |
Basrowi R.W., Rahayu E.M., Khoe L.C., Wasito E., Sundjaya T. |
57024210400;57275241200;56586245200;6506940239;57188810826; |
The road to healthy ageing: What has indonesia achieved so far? |
2021 |
Nutrients |
13 |
10 |
3441 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115825022&doi=10.3390%2fnu13103441&partnerID=40&md5=71597249210e18c8c5775dcf67e18dbe |
Occupational Medicine Division, Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Medical and Science Affairs Division, Danone Specialized Nutrition Indonesia, Jakarta, 12950, Indonesia; Department of Anthropology, Faculty of Social and Political Science Universitas Indonesia, Depok, 16424, Indonesia; Laboratorium Political Psychology, Faculty of Psychology Universitas Indonesia, Depok, 16424, Indonesia |
Basrowi, R.W., Occupational Medicine Division, Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Medical and Science Affairs Division, Danone Specialized Nutrition Indonesia, Jakarta, 12950, Indonesia; Rahayu, E.M., Department of Anthropology, Faculty of Social and Political Science Universitas Indonesia, Depok, 16424, Indonesia, Laboratorium Political Psychology, Faculty of Psychology Universitas Indonesia, Depok, 16424, Indonesia; Khoe, L.C., Occupational Medicine Division, Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Wasito, E., Medical and Science Affairs Division, Danone Specialized Nutrition Indonesia, Jakarta, 12950, Indonesia; Sundjaya, T., Medical and Science Affairs Division, Danone Specialized Nutrition Indonesia, Jakarta, 12950, Indonesia |
The World Health Organization (WHO) has projected that the world should prepare for an aging society. As the fourth most populous country in the world, the elderly population in Indonesia is also continuously growing. In 2010, the proportion of the elderly group was merely 5%, and it is expected to increase to 11% in 2035. Understanding the current situation of the adult population in Indonesia would be crucial to prepare for the future aging population. This article analyzed the current socio-demographic status, nutrition status, nutrient intake, and health profile of the current Indonesian adult population through a literature review. The key issues to prepare for healthy aging in Indonesia are summarized. Acknowledging the profile of the adult and senior adult population in Indonesia will provide beneficial information for all stakeholders in preparing Indonesia for a better healthy aging population with improved quality of life. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
Aging population; Demographic; Health profile; Healthy ageing; Nutritional status |
adult; aged; demography; female; healthy aging; human; human experiment; Indonesia; Indonesian; male; nutrient intake; nutritional status; quality of life; review; World Health Organization; epidemiology; health status; health survey; Indonesia; nutritional status; socioeconomics; Health Status; Healthy Aging; Humans; Indonesia; Nutritional Status; Public Health Surveillance; Quality of Life; Socioeconomic Factors |
MDPI |
20726643 |
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34684441 |
Review |
Q1 |
1418 |
2497 |
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209 |
Lasmono A., Ismail R.I., Kaligis F., Minayati K., Wiguna T. |
57243772800;55996895500;36604651700;57218681686;24367785700; |
Empathy quotient and systemizing quotient in elementary school children with and without attention-deficit/hyperactivity disorder: A comparative study |
2021 |
International Journal of Environmental Research and Public Health |
18 |
17 |
9231 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85114150588&doi=10.3390%2fijerph18179231&partnerID=40&md5=2177023e11ec7cb0573abfd7f195ae8f |
Department of Psychiatry, Faculty of Medicine, Dr. Cipto Mangunkusumo General Hospital, Universitas Indonesia, Jakarta, 10430, Indonesia; Child and Adolescent Psychiatry Division, Department of Psychiatry, Faculty of Medicine, Dr. Cipto Mangunkusumo General Hospital, Universitas Indonesia, Jakarta, 10430, Indonesia |
Lasmono, A., Department of Psychiatry, Faculty of Medicine, Dr. Cipto Mangunkusumo General Hospital, Universitas Indonesia, Jakarta, 10430, Indonesia; Ismail, R.I., Child and Adolescent Psychiatry Division, Department of Psychiatry, Faculty of Medicine, Dr. Cipto Mangunkusumo General Hospital, Universitas Indonesia, Jakarta, 10430, Indonesia; Kaligis, F., Child and Adolescent Psychiatry Division, Department of Psychiatry, Faculty of Medicine, Dr. Cipto Mangunkusumo General Hospital, Universitas Indonesia, Jakarta, 10430, Indonesia; Minayati, K., Child and Adolescent Psychiatry Division, Department of Psychiatry, Faculty of Medicine, Dr. Cipto Mangunkusumo General Hospital, Universitas Indonesia, Jakarta, 10430, Indonesia; Wiguna, T., Child and Adolescent Psychiatry Division, Department of Psychiatry, Faculty of Medicine, Dr. Cipto Mangunkusumo General Hospital, Universitas Indonesia, Jakarta, 10430, Indonesia |
This study compares the Empathy Quotient (EQ) and Systemizing Quotient (SQ) scores of elementary school children with and without ADHD. The study also examined their brain types and, because sex plays a big role in empathy and systemizing ability, compared the results of the boys and girls. This cross-sectional study involved 122 participants, including 61 parents of children with ADHD and 61 parents of children without ADHD. The EQ, SQ and brain types were obtained using the Empathy and Systemizing Quotient in children (EQ-/SQ-C), validated in the Indonesian language. Data was analyzed using the SPSS program version 20 for Windows, with a p-value < 0.05 for statistical significance. There was a significant difference in EQ between children with and without ADHD, the score being lower in children with ADHD. There was also a significant difference in SQ among girls with and without ADHD, but not in boys. The brain types in both groups were not significantly different. The results indicate that children with ADHD have a lower ability to empathize compared to children without ADHD. Systemizing abilities were significantly lower in girls with ADHD than in girls without. Therefore, an intervention program focusing on improving empathy and systemizing ability needs to be developed in the community. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
ADHD; Children; Empathy quotient; EQ; Indonesia; SQ; Systemizing quotient |
child health; comparative study; health care; public health; adult; Article; attention deficit disorder; behavior assessment; child; comparative study; controlled study; cross-sectional study; elementary student; empathy; empathy quotient; female; human; human relation; ICD-10; Indonesian; Kolmogorov Smirnov test; major clinical study; male; school child; self concept; sex difference; social psychology; systemizing; systemizing quotient; validation study; attention deficit disorder; brain; school; Indonesia; Attention Deficit Disorder with Hyperactivity; Brain; Child; Cross-Sectional Studies; Empathy; Female; Humans; Male; Schools |
MDPI |
16617827 |
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34501828 |
Article |
Q2 |
747 |
6560 |
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210 |
Nurhayati R.W., Cahyo R.D., Pratama G., Anggraini D., Mubarok W., Kobayashi M., Antarianto R.D. |
55748436600;57212460506;57195959221;57221606578;57208440063;20835016200;57190862806; |
Alginate-chitosan microencapsulated cells for improving cd34+ progenitor maintenance and expansion |
2021 |
Applied Sciences (Switzerland) |
11 |
17 |
7887 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85114106674&doi=10.3390%2fapp11177887&partnerID=40&md5=8aa18a5d52c69e6eb72dcb38252f4489 |
Department of Chemical Engineering, Faculty of Engineering, Universitas Indonesia, Jl. Prof. Soemantri Brojonegoro, Kampus UI, Depok, 16424, Indonesia; Stem Cells & Tissue Engineering Research Cluster, Indonesian Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, 10430, Indonesia; Department of Biotechnology, Faculty of Engineering, 2-1 Yamadaoka, Suita, Osaka, 565-0871, Japan; Department of Obstetric and Gynecology, Faculty of Medicine, Universitas Indonesia—Dr. Cipto Mangunkusumo General Hospital, Jl. Diponegoro No. 71, Central Jakarta, 10430, Indonesia; Integrated Service Unit of Stem Cell Medical Technology (IPT TK Sel Punca), Dr. Cipto Mangunkusumo General Hospital (RSCM), Jl. Diponegoro No. 71, Salemba, Central Jakarta, 10430, Indonesia; Division of Materials Science, Graduate School of Science and Technology, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, 630-0192, Japan; Division of Chemical Engineering, Department of Materials Engineering Science, Graduate School of Engineering Science, Osaka University, 1-3 Machikaneyama-cho, Toyonaka, Osaka, 560-8531, Japan; Division of Biological Science, Graduate School of Science and Technology, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, 630-0192, Japan; Department of Histology, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, 10430, Indonesia |
Nurhayati, R.W., Department of Chemical Engineering, Faculty of Engineering, Universitas Indonesia, Jl. Prof. Soemantri Brojonegoro, Kampus UI, Depok, 16424, Indonesia, Stem Cells & Tissue Engineering Research Cluster, Indonesian Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, 10430, Indonesia; Cahyo, R.D., Stem Cells & Tissue Engineering Research Cluster, Indonesian Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, 10430, Indonesia, Department of Biotechnology, Faculty of Engineering, 2-1 Yamadaoka, Suita, Osaka, 565-0871, Japan; Pratama, G., Department of Obstetric and Gynecology, Faculty of Medicine, Universitas Indonesia—Dr. Cipto Mangunkusumo General Hospital, Jl. Diponegoro No. 71, Central Jakarta, 10430, Indonesia, Integrated Service Unit of Stem Cell Medical Technology (IPT TK Sel Punca), Dr. Cipto Mangunkusumo General Hospital (RSCM), Jl. Diponegoro No. 71, Salemba, Central Jakarta, 10430, Indonesia; Anggraini, D., Stem Cells & Tissue Engineering Research Cluster, Indonesian Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, 10430, Indonesia, Division of Materials Science, Graduate School of Science and Technology, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, 630-0192, Japan; Mubarok, W., Stem Cells & Tissue Engineering Research Cluster, Indonesian Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, 10430, Indonesia, Division of Chemical Engineering, Department of Materials Engineering Science, Graduate School of Engineering Science, Osaka University, 1-3 Machikaneyama-cho, Toyonaka, Osaka, 560-8531, Japan; Kobayashi, M., Division of Biological Science, Graduate School of Science and Technology, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, 630-0192, Japan; Antarianto, R.D., Stem Cells & Tissue Engineering Research Cluster, Indonesian Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, 10430, Indonesia, Department of Histology, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Central Jakarta, 10430, Indonesia |
Protocols for isolation, characterization, and transplantation of hematopoietic stem cells (HSCs) have been well established. However, difficulty in finding human leucocyte antigens (HLA)-matched donors and scarcity of HSCs are still the major obstacles of allogeneic transplanta-tion. In this study, we developed a double-layered microcapsule to deliver paracrine factors from non-matched or low-matched HSCs to other cells. The umbilical cord blood-derived hematopoietic progenitor cells, identified as CD34+ cells, were entrapped in alginate polymer and further protected by chitosan coating. The microcapsules showed no toxicity for surrounding CD34+ cells. When CD34+ cells-loaded microcapsules were co-cultured with bare CD34+ cells that have been collected from unrelated donors, the microcapsules affected surrounding cells and increased the percentage of CD34+ cell population. This study is the first to report the potency of alginate-chitosan microcap-sules containing non-HLA-matched cells for improving proliferation and progenitor maintenance of CD34+ cells. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
Alginate; CD34; Chitosan; Hematopoietic; Megakaryocyte; Microencapsulation; Progenitor; Proliferation; Stem cells |
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MDPI |
20763417 |
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Article |
Q2 |
435 |
11324 |
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211 |
Angelin T.C., Bardosono S., Shinta D., Fahmida U. |
57235777300;21933841000;57237520500;14420783500; |
Growth, dietary intake, and vitamin D receptor (VDR) promoter genotype in Indonesian school-age children |
2021 |
Nutrients |
13 |
9 |
2904 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85113740878&doi=10.3390%2fnu13092904&partnerID=40&md5=c7a37360e57bb2d193a5b68571b677d7 |
Southeast Asian Ministers of Education Organization Regional Center for Food and Nutrition (SEAMEO RECFON)-Pusat Kajian Gizi Regional, Universitas Indonesia, Jakarta, 10430, Indonesia; Department of Nutrition, Faculty of Medicine, Universitas Indonesia—Dr. Cipto Mangunkusumo General Hospital, Jakarta, 10430, Indonesia |
Angelin, T.C., Southeast Asian Ministers of Education Organization Regional Center for Food and Nutrition (SEAMEO RECFON)-Pusat Kajian Gizi Regional, Universitas Indonesia, Jakarta, 10430, Indonesia, Department of Nutrition, Faculty of Medicine, Universitas Indonesia—Dr. Cipto Mangunkusumo General Hospital, Jakarta, 10430, Indonesia; Bardosono, S., Department of Nutrition, Faculty of Medicine, Universitas Indonesia—Dr. Cipto Mangunkusumo General Hospital, Jakarta, 10430, Indonesia; Shinta, D., Southeast Asian Ministers of Education Organization Regional Center for Food and Nutrition (SEAMEO RECFON)-Pusat Kajian Gizi Regional, Universitas Indonesia, Jakarta, 10430, Indonesia; Fahmida, U., Southeast Asian Ministers of Education Organization Regional Center for Food and Nutrition (SEAMEO RECFON)-Pusat Kajian Gizi Regional, Universitas Indonesia, Jakarta, 10430, Indonesia |
Nutrition has been known as a predominant factor associated with stunting. However, some studies have discovered a genetic contribution in calcium absorption that will affect growth, known as the VDR gene. The aim of this study was to assess the association between VDR gene polymorphism and dietary intake towards height-for-age z-score (HAZ) of elementary school children in Malang District, East Java. This study analyzed the baseline of a randomized trial in East Java, Indonesia. School children aged 8–10 years old (n = 142) were included in this study. Energy, protein, calcium, and vitamin D intakes were obtained using 4-day 24-h dietary recalls. Two SNPs located in the promoter region of VDR gene were selected (rs11568820 and rs4516035) and analyzed using Real-Time PCR. The result showed a significant correlation between energy and protein intake with HAZ of the children (p = 0.030 and p = 0.016, respectively). The association between VDR gene and HAZ was not found (p > 0.05). Adjusted by other factors, protein intake was significantly correlated with HAZ (β = 0.034, 95% CI 0.015–0.052, p < 0.001, adj. R2 = 0.089). The children in our study had a favorable VDR gene genotype, however the effect of VDR gene promoter activity might not be revealed due to very low vitamin D and calcium intake to stimulate intestinal calcium absorption which in turn affects HAZ. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
Calcium; Children; Dietary intake; Height-for-age z-score (HAZ); Indonesia; Stunting; VDR gene; Vitamin D |
calcium; DNA; protein; vitamin D; vitamin D receptor; calcitriol receptor; vitamin D; Article; body height; calcium absorption; calcium intake; caloric intake; child; child growth; controlled study; correlational study; cross-sectional study; diarrhea; dietary intake; elementary student; female; food frequency questionnaire; gene frequency; genetic variability; genotype; helminthiasis; heterozygote; human; Indonesia; macronutrient intake; male; micronutrient intake; pathogenesis; prevalence; primary school; promoter region; protein intake; randomized controlled trial; real time polymerase chain reaction; respiratory tract infection; school child; semi quantitative food frequency questionnaire; single nucleotide polymorphism; stunting; sun exposure; sunlight; vitamin intake; administration |
MDPI |
20726643 |
|
34578782 |
Article |
Q1 |
1418 |
2497 |
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283 |
Meilia P.D.I., Zeegers M.P., Herkutanto, Freeman M.D. |
57204065074;7003691618;57204069374;34769701500; |
Medicolegal causation investigation of bacterial endocarditis associated with an oral surgery practice using the INFERENCE approach |
2021 |
International Journal of Environmental Research and Public Health |
18 |
14 |
7530 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85110118162&doi=10.3390%2fijerph18147530&partnerID=40&md5=c18a2f743bdf484bc116e962d9bb593b |
Care and Public Health Research Institute (CAPHRI), Maastricht University Medical Center+, Universiteitssingel 40, Maastricht, 6229 ER, Netherlands; Department of Forensic Medicine and Medicolegal Studies, Faculty of Medicine, University of Indonesia, Jl. Salemba Raya No. 4, Salemba, Jakarta Pusat, 10430, Indonesia |
Meilia, P.D.I., Care and Public Health Research Institute (CAPHRI), Maastricht University Medical Center+, Universiteitssingel 40, Maastricht, 6229 ER, Netherlands; Zeegers, M.P., Care and Public Health Research Institute (CAPHRI), Maastricht University Medical Center+, Universiteitssingel 40, Maastricht, 6229 ER, Netherlands; Herkutanto, Department of Forensic Medicine and Medicolegal Studies, Faculty of Medicine, University of Indonesia, Jl. Salemba Raya No. 4, Salemba, Jakarta Pusat, 10430, Indonesia; Freeman, M.D., Care and Public Health Research Institute (CAPHRI), Maastricht University Medical Center+, Universiteitssingel 40, Maastricht, 6229 ER, Netherlands |
Investigating causation is a primary goal in forensic/legal medicine, aiming to establish the connection between an unlawful/negligent act and an adverse outcome. In malpractice litigation involving a healthcare-associated infection due to a failure of infection prevention and control prac-tices, the medicolegal causal analysis needs to quantify the individual causal probabilities to meet the evidentiary requirements of the court. In this paper, we present the investigation of the most probable cause of bacterial endocarditis in a patient who underwent an invasive procedure at a dental/oral surgical practice where an outbreak of bacterial endocarditis had already been identified by the state Department of Health. We assessed the probability that the patient’s endocarditis was part of the outbreak versus that it was an unrelated sporadic infection using the INFERENCE (Integration of Forensic Epidemiology and the Rigorous Evaluation of Causation Elements) approach to medicolegal causation analysis. This paper describes the step-by-step application of the INFERENCE approach to demonstrate its utility in quantifying the probability of causation. The use of INFERENCE provides the court with an evidence-based, transparent, and reliable guide to determine liability, causation, and damages. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
Bacterial endocarditis; Infection prevention and control practices; INFERENCE approach; Malpractice litigation; Medicolegal causal analysis; Quantification of causation |
bacterium; disease control; forensic science; health care; infectious disease; medicine; oral health; quantitative analysis; adult; aged; aortic regurgitation; Article; bacteremia; bacterial endocarditis; cardiomegaly; dizziness; dyspnea; electrocardiography; emergency ward; Enterococcus faecalis; female; fever; follow up; hospitalization; human; infection prevention; legal epidemiology; lumpectomy; male; malpractice; night sweat; nuclear magnetic resonance imaging; oral surgery; public health; transesophageal echocardiography; bacterial endocarditis; causality; forensic medicine; malpractice; Bacteria (microorganisms); Causality; Endocarditis, Bacterial; Forensic Medicine; Humans; Malpractice; Oral Surgical Procedures |
MDPI |
16617827 |
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34299979 |
Article |
Q2 |
747 |
6560 |
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315 |
Purnomo G.A., Mitchell K.J., O’connor S., Kealy S., Taufik L., Schiller S., Rohrlach A., Cooper A., Llamas B., Sudoyo H., Teixeira J.C., Tobler R. |
56262110300;55937278100;57192065848;57016654100;57225108034;57225091129;56674549200;57225849511;8695218700;6603548824;56290678400;55780763900; |
Mitogenomes reveal two major influxes of papuan ancestry across wallacea following the last glacial maximum and austronesian contact |
2021 |
Genes |
12 |
7 |
965 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85109185551&doi=10.3390%2fgenes12070965&partnerID=40&md5=046fa96fdfa7683fb4a23714ea942197 |
Australian Centre for Ancient DNA, School of Biological Sciences, University of Adelaide, Adelaide, 5005, Australia; Genome Diversity and Diseases Laboratory, Eijkman Institute of Molecular Biology, Jakarta, 10430, Indonesia; ARC Centre of Excellence for Australian Biodiversity and Heritage, University of Adelaide, Adelaide, 5005, Australia; Archaeology and Natural History, School of Culture, History and Language, College of Asia and the Pacific, Australian National University, Canberra, 2601, Australia; ARC Centre of Excellence for Australian Biodiversity and Heritage, Australian National University, Canberra, 2601, Australia; Evolution of Cultural Diversity Initiative, Australian National University, Canberra, 2601, Australia; ARC Centre of Excellence for Mathematical and Statistical Frontiers, School of Mathematical Sciences, The University of Adelaide, Adelaide, 5005, Australia; Department of Archaeogenetics, Max Planck Institute for the Science of Human History, Jena, 07745, Germany; Blue Sky Genetics, P.O. Box 287, Adelaide, 5137, Australia; South Australian Museum, Adelaide, 5000, Australia; Environment Institute, University of Adelaide, Adelaide, 5005, Australia; National Centre for Indigenous Genomics, Australian National University, Canberra, 2601, Australia; Department of Medical Biology, Faculty of Medicine, University of Indonesia, Jakarta, 10430, Indonesia; Sydney Medical School, University of Sydney, Sydney, 2050, Australia |
Purnomo, G.A., Australian Centre for Ancient DNA, School of Biological Sciences, University of Adelaide, Adelaide, 5005, Australia, Genome Diversity and Diseases Laboratory, Eijkman Institute of Molecular Biology, Jakarta, 10430, Indonesia; Mitchell, K.J., Australian Centre for Ancient DNA, School of Biological Sciences, University of Adelaide, Adelaide, 5005, Australia, ARC Centre of Excellence for Australian Biodiversity and Heritage, University of Adelaide, Adelaide, 5005, Australia; O’connor, S., Archaeology and Natural History, School of Culture, History and Language, College of Asia and the Pacific, Australian National University, Canberra, 2601, Australia, ARC Centre of Excellence for Australian Biodiversity and Heritage, Australian National University, Canberra, 2601, Australia; Kealy, S., Archaeology and Natural History, School of Culture, History and Language, College of Asia and the Pacific, Australian National University, Canberra, 2601, Australia, ARC Centre of Excellence for Australian Biodiversity and Heritage, Australian National University, Canberra, 2601, Australia, Evolution of Cultural Diversity Initiative, Australian National University, Canberra, 2601, Australia; Taufik, L., Genome Diversity and Diseases Laboratory, Eijkman Institute of Molecular Biology, Jakarta, 10430, Indonesia; Schiller, S., ARC Centre of Excellence for Mathematical and Statistical Frontiers, School of Mathematical Sciences, The University of Adelaide, Adelaide, 5005, Australia; Rohrlach, A., ARC Centre of Excellence for Mathematical and Statistical Frontiers, School of Mathematical Sciences, The University of Adelaide, Adelaide, 5005, Australia, Department of Archaeogenetics, Max Planck Institute for the Science of Human History, Jena, 07745, Germany; Cooper, A., Blue Sky Genetics, P.O. Box 287, Adelaide, 5137, Australia, South Australian Museum, Adelaide, 5000, Australia; Llamas, B., Australian Centre for Ancient DNA, School of Biological Sciences, University of Adelaide, Adelaide, 5005, Australia, ARC Centre of Excellence for Australian Biodiversity and Heritage, University of Adelaide, Adelaide, 5005, Australia, Environment Institute, University of Adelaide, Adelaide, 5005, Australia, National Centre for Indigenous Genomics, Australian National University, Canberra, 2601, Australia; Sudoyo, H., Genome Diversity and Diseases Laboratory, Eijkman Institute of Molecular Biology, Jakarta, 10430, Indonesia, Department of Medical Biology, Faculty of Medicine, University of Indonesia, Jakarta, 10430, Indonesia, Sydney Medical School, University of Sydney, Sydney, 2050, Australia; Teixeira, J.C., Australian Centre for Ancient DNA, School of Biological Sciences, University of Adelaide, Adelaide, 5005, Australia, ARC Centre of Excellence for Australian Biodiversity and Heritage, University of Adelaide, Adelaide, 5005, Australia, Evolution of Cultural Diversity Initiative, Australian National University, Canberra, 2601, Australia; Tobler, R., Australian Centre for Ancient DNA, School of Biological Sciences, University of Adelaide, Adelaide, 5005, Australia, ARC Centre of Excellence for Australian Biodiversity and Heritage, University of Adelaide, Adelaide, 5005, Australia, Evolution of Cultural Diversity Initiative, Australian National University, Canberra, 2601, Australia |
The tropical archipelago of Wallacea contains thousands of individual islands interspersed between mainland Asia and Near Oceania, and marks the location of a series of ancient oceanic voyages leading to the peopling of Sahul—i.e., the former continent that joined Australia and New Guinea at a time of lowered sea level—by 50,000 years ago. Despite the apparent deep antiquity of human presence in Wallacea, prior population history research in this region has been hampered by patchy archaeological and genetic records and is largely concentrated upon more recent history that follows the arrival of Austronesian seafarers ~3000–4000 years ago (3–4 ka). To shed light on the deeper history of Wallacea and its connections with New Guinea and Australia, we performed phylogeographic analyses on 656 whole mitogenomes from these three regions, including 186 new samples from eight Wallacean islands and three West Papuan populations. Our results point to a surprisingly dynamic population history in Wallacea, marked by two periods of extensive demographic change concentrated around the Last Glacial Maximum ~15 ka and post-Austronesian contact ~3 ka. These changes appear to have greatly diminished genetic signals informative about the original peopling of Sahul, and have important implications for our current understanding of the population history of the region. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
Human migrations; Mitochondria; MtDNA; Phylogeography; Sahul |
mitochondrial DNA; ancestry group; Article; Asia; Australia; Austronesian people; biogeographic region; gene sequence; haplotype; human; last glacial maximum; migration; mitochondrial genome; Papua New Guinea; Philippines; phylogeny; phylogeography; polymerase chain reaction; population size; population structure; sailor; sequence alignment; simulation; Wallacea; animal; archeology; beetle; female; genetics; history; male; mitochondrial genome; Pacific islands; phylogeny; phylogeography; population genetics; Animals; Archaeology; Asia; Australia; Coleoptera; Female; Genetics, Population; Genome, Mitochondrial; Haplotypes; History, Ancient; Humans; Male; New Guinea; Oceania; Phylogeny; Phylogeography |
MDPI |
20734425 |
|
34202821 |
Article |
Q2 |
1337 |
2737 |
|
|
335 |
Anurogo D., Budi N.Y.P., Ngo M.-H.T., Huang Y.-H., Pawitan J.A. |
57224408026;57200656694;57222023578;57154840200;6508348067; |
Cell and gene therapy for anemia: Hematopoietic stem cells and gene editing |
2021 |
International Journal of Molecular Sciences |
22 |
12 |
6275 |
|
|
|
1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85107482996&doi=10.3390%2fijms22126275&partnerID=40&md5=fea16158471961b74a29fcf9cb158461 |
International PhD Program for Cell Therapy and Regeneration Medicine, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan; Department of Biochemistry and Molecular Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan; Faculty of Medicine and Health Sciences, Universitas Muhammadiyah Makassar, Makassar, 90221, Indonesia; Research Center of Cell Therapy and Regeneration Medicine, Taipei Medical University, Taipei, 11031, Taiwan; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan; Center for Reproductive Medicine, Taipei Medical University Hospital, Taipei, 11031, Taiwan; Comprehensive Cancer Center, Taipei Medical University, Taipei, 11031, Taiwan; Research Center of Cancer Translational Medicine, Taipei Medical University, Taipei, 11031, Taiwan; PhD Program for Translational Medicine, College of Medical Science and Technology, Taipei Medical University, Taipei, 11031, Taiwan; Department of Histology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Stem Cell and Tissue Engineering Research Center, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia |
Anurogo, D., International PhD Program for Cell Therapy and Regeneration Medicine, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan, Department of Biochemistry and Molecular Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan, Faculty of Medicine and Health Sciences, Universitas Muhammadiyah Makassar, Makassar, 90221, Indonesia; Budi, N.Y.P., International PhD Program for Cell Therapy and Regeneration Medicine, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan, Department of Biochemistry and Molecular Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan; Ngo, M.-H.T., International PhD Program for Cell Therapy and Regeneration Medicine, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan, Department of Biochemistry and Molecular Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan; Huang, Y.-H., International PhD Program for Cell Therapy and Regeneration Medicine, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan, Department of Biochemistry and Molecular Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan, Research Center of Cell Therapy and Regeneration Medicine, Taipei Medical University, Taipei, 11031, Taiwan, Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan, Center for Reproductive Medicine, Taipei Medical University Hospital, Taipei, 11031, Taiwan, Comprehensive Cancer Center, Taipei Medical University, Taipei, 11031, Taiwan, Research Center of Cancer Translational Medicine, Taipei Medical University, Taipei, 11031, Taiwan, PhD Program for Translational Medicine, College of Medical Science and Technology, Taipei Medical University, Taipei, 11031, Taiwan; Pawitan, J.A., Department of Histology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Stem Cell and Tissue Engineering Research Center, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia |
Hereditary anemia has various manifestations, such as sickle cell disease (SCD), Fanconi anemia, glucoseā6āphosphate dehydrogenase deficiency (G6PDD), and thalassemia. The available management strategies for these disorders are still unsatisfactory and do not eliminate the main causes. As genetic aberrations are the main causes of all forms of hereditary anemia, the optimal approach involves repairing the defective gene, possibly through the transplantation of normal hematopoietic stem cells (HSCs) from a normal matching donor or through gene therapy approaches (either in vivo or ex vivo) to correct the patient’s HSCs. To clearly illustrate the importance of cell and gene therapy in hereditary anemia, this paper provides a review of the genetic aberration, epidemiology, clinical features, current management, and cell and gene therapy en-deavors related to SCD, thalassemia, Fanconi anemia, and G6PDD. Moreover, we expound the future research direction of HSC derivation from induced pluripotent stem cells (iPSCs), strategies to edit HSCs, gene therapy risk mitigation, and their clinical perspectives. In conclusion, geneācorrected hematopoietic stem cell transplantation has promising outcomes for SCD, Fanconi anemia, and thalassemia, and it may overcome the limitation of the source of allogenic bone marrow transplantation. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
Anemia; Cell therapy; Gene editing; Gene therapy; Hematopoietic stem cells |
antisickling agent; BRCA1 protein; BRCA2 protein; Fanconi anemia group A protein; Fanconi anemia group b protein; Fanconi anemia group C protein; Fanconi anemia group D2 protein; Fanconi anemia group E protein; Fanconi anemia group F protein; Fanconi anemia group G protein; Fanconi anemia group i protein; Fanconi anemia group j protein; Fanconi anemia group L protein; hematologic agent; hemoglobin beta chain; hemoglobin F; nuclear protein; partner and localizer of BRCA2; Rad51 protein; Rad51c protein; unclassified drug; acute chest syndrome; anemia; aplastic anemia; arm malformation; Article; asplenia; blood transfusion; cafe au lait spot; cell therapy; cerebrovascular accident; chromosome aberration; chronic nonspherocytic hemolytic anemia; clinical feature; clinical outcome; congenital d |
MDPI |
16616596 |
|
34200975 |
Article |
Q1 |
1455 |
2384 |
|
|
365 |
Duc N.T.M., Loc L.Q., Alhady S.T.M., Sabir D.M.E., Mai L.N., Dumre S.P., Hassan A.K., Giang T.V., Thach P.N., Truong L.V., Ravikulan R., Raut A., Dayyab F.M., Trang V.T.T., Huy N.T., Imoto A., Dumre R.B., Ranabhat K., Sharma G.N., Habaj N.A., Elnoamany S., Aziz J.M.A., Crispino K.T., Alsuwiyah S., Hussein R.M., Hama D.J., Morena G.J.V., Aritonang R.S., Rocha I.C.N., Pavlenko D., Kareem H.F.H., Antora R.J., Lopez A.S.E., Gubari M.I.M., Koonrungsesomboon N., Takuathung M.N., Ruengorn C., Nochaiwong S., Kanjanarat P., Elhassan S.M., Dzhemiliev A., Olvera B.P.G., Haque M.A., Ullah I., Dajti I., Kërpaçi J., Vrapi E., Venkatesh U., Hassan Z., Ahmed Z.S., Alrahman M.F., Khanh T.T., Qarawi A.T.A., Kudlatska-Tyshko I., Ali I., Ng S.J., Nghia P.T., Pavlenko M., Abbas K.S., Omran H.A.M., Rezq C.S., Ibrahim M.I.A., Ragheb M.S., Monib F.A., Said A.E., Ahmed S.F., Hamed Z.H., Nageh M.A., Sayed E., Shibani M., Ismail A.H., Alzabibi M.A., Sawaf B., Chuah J., Lim Y.L., Jee Y.S., Hamed A.H.M., Miranda A.V., Kubota K., Aoki K., Gyanwali P., Dhimal M., Koirala P., Adhikari K., Lucas F., Ordóñez J.N.P., Aburto J.T.O., Chong L.C., Younes B., Pavlenko R., Iqtadar S., Ghani U., Mumtaz S.U., Khan A.A., TMGH-Global COVID-19 Collaborative |
57199622107;57218120041;57224078312;57224082661;57224089160;35321918400;57220065688;57224091973;57224072368;57224082619;57224095725;57218407158;56580399700;57224073089;57209480434;56216340000;57224070842;56622984700;57225749183;57224068325;57223975589;57224097004;57224087649;57222960525;57224071699;57224073174;57224086154;57224080363;57223283646;57204158719;57224068925;57224089935;57224081202;57210795029;56288783600;57224077120;53878308600;57189848094;22992871700;57224069299;57220175050;57224091480;57218448682;57211152020;57218993911;57224092581;57221615805;57218892210;57215818914;57225670959;57224080553;57224086420;57224096129;57224087241;57223368799;57223195386;57224069007;57224069023;57223185385;57224095939;57224089287;57224086484;57224099028;57219123965;57222138764;57224098010;57224076675;57224090223;57224097163;57219773848;57224091545;57219774505;57195679503;57224073773;57224092806;57224072085;57224070356;57222664687;57201680054;57224094037;57194476849;54941157300;57224089702;56339701500;57224080691;57224090794;57224082163;57224092414;57224079470;56594973400;37661545300;57224097377;57224079051;57224093195; |
Psychological impacts and post-traumatic stress disorder among people under COVID-19 quarantine and isolation: A global survey |
2021 |
International Journal of Environmental Research and Public Health |
18 |
11 |
5719 |
|
|
|
4 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85106936924&doi=10.3390%2fijerph18115719&partnerID=40&md5=843d98405f6225b81732a50db6f59ae0 |
Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Viet Nam; Faculty of Medicine, University of Gezira, Wad Medani, Sudan; Department of Internal Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Viet Nam; Central Department of Microbiology, Tribhuvan University, Kathmandu, Nepal; Faculty of Medicine, South Valley University, Qena, Egypt; Department of Infectious Disease, Hanoi Medical University, Hanoi, Viet Nam; Traditional Medicine Hospital, Ministry of the Public Security, Hanoi, Viet Nam; Southern Adelaide Local Health Network, Adelaide, Australia; Rajarshee Chhatrapati Shahu Maharaj Govt Medical College, Kolhapur, India; Infectious Disease Hospital, Kano, Nigeria; National Hospital of Traditional Medicine, Hanoi, Viet Nam; School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan; Ministry of Health and Population, Kathmandu, Nepal; Institute of Medicine, Tribhuvan University, Kathmandu, Nepal; Faculty of medicine, University of Tours, Tours, France; Faculty of Medicine, Menoufia University, Menoufia, Egypt; Medical Laboratory Science, College of Health Sciences, University of Human Development, Sulaymaniyah, Kurdistan region, Iraq; Baxshin Research Center, Baxshin Hospital, Sulaymaniyah, Kurdistan Region, Iraq; Health Emergency Management Bureau, Department of Health, Manila, Philippines; Faculty of Medicine, University of Tripoli, Tripoli, Libyan Arab Jamahiriya; Baxshin Research Center, Baxshin Hospital, Sulaymaniyah, Kurdistan region, Iraq; Faculty of Medicine, Trisakti University, Jakarta, Indonesia; America Evangelical University, Los Angeles, CA, United States; Yadika General Hospital, Jakarta, Indonesia; School of Medicine, Centro Escolar University, Manila, Philippines; Department of Ophthalmology, Bogomolets National Medical University, Kyiv, Ukraine; Department of Psychiatry, Mental Health Center, Awesar Medical Building Sulaymaniyah, Kurdistan region, Iraq; Qilu Hospital, Shandong University, Jinan, Shandong, China; Faculty of Medicine, Pontificia Universidad Católica del Ecuador, Quito, Ecuador; Department of Family and Community Medicine, College of Medicine, University of Sulaimaniyah, Sulaimaniyah, Kurdistan Region, Iraq; Department of Pharmacology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; Department of Pharmaceutical Care, Faculty of Pharmacy, Chiang Mai University, Chiang Mai, Thailand; Faculty of Medicine, Alneelain University, Khartoum, Sudan; Shalimov National Institute of Surgery and Transplantology, Kyiv, Ukraine; Autonomous University of Mexico State, Toluca, Mexico; Department of Orthopedic Surgery, Yan an hospital affiliated to Kunming Medical University, Kunming, Yunnan, China; Kabir Medical College, Gandhara University, Peshawar, Pakistan; UHOG ‘Koço Gliozheni’, Tirana, Albania; Department of Community Medicine, Vardhman Mahavir Medical College & Safdarjung Hospital, New Delhi, India; Cardiology department, Lady Reading Hospital, Peshawar, Pakistan; Faculty of Medicine, Cairo University, Egypt; University of Bakhat alruda, Ed Dueim, Sudan; Faculty of Medicine, School of Medicine and Pharmacy, Da Nang University, Da Nang City, Viet Nam; Lower Westchester Medical Associates, P.C., Mount Vernon, NY, United States; Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine; Paraplegic Center, Hayatabad Peshawar, Pakistan; Department of Medicine, Crozer-Chester Medical Center, Upland, PA, United States; Faculty of Medicine, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Viet Nam; Kyiv City Pediatric Diagnostic Center, Kyiv, Ukraine; Faculty of Medicine, Alexandria University, Alexandria, Egypt; Faculty of Medicine, Assiut University, Assiut, Egypt; Faculty of Medicine, Syrian Private University, Damascus, Syrian Arab Republic; School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia; Faculty of Medicine, Cairo University, Cairo, Egypt; Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Department of Biostatistics, Yokohama City University, Yokohama, Japan; Graduate School of Nursing, Chiba University, Chiba, Japan; Nepal Health Research Council, Kathmandu, Nepal; Faculty of Medicine, University of Lisbon, Lisbon, Portugal; Faculty of Medicine, Catholic University of Honduras, Honduras; Faculty of Medicine, Universidad de La Frontera, Temuco, Chile; School of Data Sciences, Perdana University, Kuala Lumpur, Malaysia; Faculty of Medicine and Pharmacy, Cadi Ayyad University, Marrakesh, Morocco; Bogomolets National Medical University, Kyiv, Ukraine; King Edward Medical University, Lahore, Pakistan; Directorate General Health Services, Lahore, Pakistan; North Medical Ward, KEMU/Mayo Hospital, Lahore, Pakistan; Khyber Teaching Hospital, Peshawar, Pakistan |
Duc, N.T.M., Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Viet Nam; Loc, L.Q., Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Viet Nam; Alhady, S.T.M., Faculty of Medicine, University of Gezira, Wad Medani, Sudan; Sabir, D.M.E., Faculty of Medicine, University of Gezira, Wad Medani, Sudan; Mai, L.N., Department of Internal Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Viet Nam; Dumre, S.P., Central Department of Microbiology, Tribhuvan University, Kathmandu, Nepal; Hassan, A.K., Faculty of Medicine, South Valley University, Qena, Egypt; Giang, T.V., Department of Infectious Disease, Hanoi Medical University, Hanoi, Viet Nam; Thach, P.N., Department of Infectious Disease, Hanoi Medical University, Hanoi, Viet Nam; Truong, L.V., Traditional Medicine Hospital, Ministry of the Public Security, Hanoi, Viet Nam; Ravikulan, R., Southern Adelaide Local Health Network, Adelaide, Australia; Raut, A., Rajarshee Chhatrapati Shahu Maharaj Govt Medical College, Kolhapur, India; Dayyab, F.M., Infectious Disease Hospital, Kano, Nigeria; Trang, V.T.T., National Hospital of Traditional Medicine, Hanoi, Viet Nam; Huy, N.T., School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan; Imoto, A., School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan; Dumre, R.B., School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan; Ranabhat, K., Ministry of Health and Population, Kathmandu, Nepal, Institute of Medicine, Tribhuvan University, Kathmandu, Nepal; Sharma, G.N., Ministry of Health and Population, Kathmandu, Nepal; Habaj, N.A., Faculty of medicine, University of Tours, Tours, France; Elnoamany, S., Faculty of Medicine, Menoufia University, Menoufia, Egypt; Aziz, J.M.A., Medical Laboratory Science, College of Health Sciences, University of Human Development, Sulaymaniyah, Kurdistan region, Iraq, Baxshin Research Center, Baxshin Hospital, Sulaymaniyah, Kurdistan Region, Iraq; Crispino, K.T., Health Emergency Management Bureau, Department of Health, Manila, Philippines; Alsuwiyah, S., Faculty of Medicine, University of Tripoli, Tripoli, Libyan Arab Jamahiriya; Hussein, R.M., Baxshin Research Center, Baxshin Hospital, Sulaymaniyah, Kurdistan region, Iraq; Hama, D.J., Baxshin Research Center, Baxshin Hospital, Sulaymaniyah, Kurdistan region, Iraq; Morena, G.J.V., Faculty of Medicine, Trisakti University, Jakarta, Indonesia, America Evangelical University, Los Angeles, CA, United States; Aritonang, R.S., Faculty of Medicine, Trisakti University, Jakarta, Indonesia, Yadika General Hospital, Jakarta, Indonesia; Rocha, I.C.N., School of Medicine, Centro Escolar University, Manila, Philippines; Pavlenko, D., Department of Ophthalmology, Bogomolets National Medical University, Kyiv, Ukraine; Kareem, H.F.H., Department of Psychiatry, Mental Health Center, Awesar Medical Building Sulaymaniyah, Kurdistan region, Iraq; Antora, R.J., Qilu Hospital, Shandong University, Jinan, Shandong, China; Lopez, A.S.E., Faculty of Medicine, Pontificia Universidad Católica del Ecuador, Quito, Ecuador; Gubari, M.I.M., Department of Family and Community Medicine, College of Medicine, University of Sulaimaniyah, Sulaimaniyah, Kurdistan Region, Iraq; Koonrungsesomboon, N., Department of Pharmacology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; Takuathung, M.N., Department of Pharmacology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; Ruengorn, C., Department of Pharmaceutical Care, Faculty of Pharmacy, Chiang Mai University, Chiang Mai, Thailand; Nochaiwong, S., Department of Pharmaceutical Care, Faculty of Pharmacy, Chiang Mai University, Chiang Mai, Thailand; Kanjanarat, P., Department of Pharmaceutical Care, Faculty of Pharmacy, Chiang Mai University, Chiang Mai, Thailand; Elhassan, S.M., Faculty of Medicine, Alneelain University, Khartoum, Sudan; Dzhemiliev, A., Shalimov National Institute of Surgery and Transplantology, Kyiv, Ukraine; Olvera, B.P.G., Autonomous University of Mexico State, Toluca, Mexico; Haque, M.A., Department of Orthopedic Surgery, Yan an hospital affiliated to Kunming Medical University, Kunming, Yunnan, China; Ullah, I., Kabir Medical College, Gandhara University, Peshawar, Pakistan; Dajti, I., UHOG ‘Koço Gliozheni’, Tirana, Albania; Kërpaçi, J., UHOG ‘Koço Gliozheni’, Tirana, Albania; Vrapi, E., UHOG ‘Koço Gliozheni’, Tirana, Albania; Venkatesh, U., Department of Community Medicine, Vardhman Mahavir Medical College & Safdarjung Hospital, New Delhi, India; Hassan, Z., Cardiology department, Lady Reading Hospital, Peshawar, Pakistan; Ahmed, Z.S., Faculty of Medicine, Cairo University, Egypt; Alrahman, M.F., University of Bakhat alruda, Ed Dueim, Sudan; Khanh, T.T., Faculty of Medicine, School of Medicine and Pharmacy, Da Nang University, Da Nang City, Viet Nam; Qarawi, A.T.A., Lower Westchester Medical Associates, P.C., Mount Vernon, NY, United States; Kudlatska-Tyshko, I., Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine; Ali, I., Paraplegic Center, Hayatabad Peshawar, Pakistan; Ng, S.J., Department of Medicine, Crozer-Chester Medical Center, Upland, PA, United States; Nghia, P.T., Faculty of Medicine, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Viet Nam; Pavlenko, M., Kyiv City Pediatric Diagnostic Center, Kyiv, Ukraine; Abbas, K.S., Faculty of Medicine, Alexandria University, Alexandria, Egypt; Omran, H.A.M., Faculty of Medicine, Alexandria University, Alexandria, Egypt; Rezq, C.S., Faculty of Medicine, Alexandria University, Alexandria, Egypt; Ibrahim, M.I.A., Faculty of Medicine, Alexandria University, Alexandria, Egypt; Ragheb, M.S., Faculty of Medicine, Alexandria University, Alexandria, Egypt; Monib, F.A., Faculty of Medicine, Assiut University, Assiut, Egypt; Said, A.E., Faculty of Medicine, Assiut University, Assiut, Egypt; Ahmed, S.F., Faculty of Medicine, Assiut University, Assiut, Egypt; Hamed, Z.H., Faculty of Medicine, Assiut University, Assiut, Egypt; Nageh, M.A., Faculty of Medicine, Assiut University, Assiut, Egypt; Sayed, E., Faculty of Medicine, Assiut University, Assiut, Egypt; Shibani, M., Faculty of Medicine, Syrian Private University, Damascus, Syrian Arab Republic; Ismail, A.H., Faculty of Medicine, Syrian Private University, Damascus, Syrian Arab Republic; Alzabibi, M.A., Faculty of Medicine, Syrian Private University, Damascus, Syrian Arab Republic; Sawaf, B., Faculty of Medicine, Syrian Private University, Damascus, Syrian Arab Republic; Chuah, J., School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia; Lim, Y.L., School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia; Jee, Y.S., School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia; Hamed, A.H.M., Faculty of Medicine, Cairo University, Cairo, Egypt; Miranda, A.V., Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Kubota, K., Department of Biostatistics, Yokohama City University, Yokohama, Japan; Aoki, K., Graduate School of Nursing, Chiba University, Chiba, Japan; Gyanwali, P., Nepal Health Research Council, Kathmandu, Nepal; Dhimal, M., Nepal Health Research Council, Kathmandu, Nepal; Koirala, P., Nepal Health Research Council, Kathmandu, Nepal; Adhikari, K., Nepal Health Research Council, Kathmandu, Nepal; Lucas, F., Faculty of Medicine, University of Lisbon, Lisbon, Portugal; Ordóñez, J.N.P., Faculty of Medicine, Catholic University of Honduras, Honduras; Aburto, J.T.O., Faculty of Medicine, Universidad de La Frontera, Temuco, Chile; Chong, L.C., School of Data Sciences, Perdana University, Kuala Lumpur, Malaysia; Younes, B., Faculty of Medicine and Pharmacy, Cadi Ayyad University, Marrakesh, Morocco; Pavlenko, R., Bogomolets National Medical University, Kyiv, Ukraine; Iqtadar, S., King Edward Medical University, Lahore, Pakistan; Ghani, U., Directorate General Health Services, Lahore, Pakistan; Mumtaz, S.U., North Medical Ward, KEMU/Mayo Hospital, Lahore, Pakistan; Khan, A.A., Khyber Teaching Hospital, Peshawar, Pakistan; TMGH-Global COVID-19 Collaborative |
Understanding the presence of post-traumatic stress disorder (PTSD) symptoms in quarantined/ isolated individuals is essential for decreasing morbidity and mortality caused by the COVID-19 pandemic. However, there is a paucity of evidence quantifying PTSD status globally during confinement in quarantine/isolation facilities during COVID-19. Therefore, we aimed to assess the PTSD status and factors contributing to PTSD development in quarantined/isolated people during pandemic. Using the Impact of Event Scale-Revised (IES-R) scale, our multicentre, multinational, and cross-sectional online survey assessed the psychological impacts on the quarantine/isolation experience of participants suspected or confirmed to have COVID-19, their PTSD status, and various correlates with developing PTSD. We had 944 (35.33%) valid responses (51.1% from females), mostly from Asian countries (635, 71.4%), and 33.9% were healthcare workers. The number of quarantine days in the PTSD symptoms group (using the IES-R cutoff of 24 for symptomatic or full PTSD) was significantly shorter compared to the non-PTSD group (14 (range 14-40) vs. 14 (14-23.75), p = 0.031). Lower rates of PTSD symptoms were observed in participants practicing Buddhist religion than in participants having no religion (OR: 0.30; 95% CI: 0.13-0.68; p = 0.005); individuals with vocational training had a higher risk of developing PTSD symptoms (OR: 2.28 (1.04-5.15); p = 0.043) compared to university graduates. Individuals forced to be quarantined/isolated had higher odds of developing PTSD symptoms than those voluntarily quarantined/isolated (OR: 2.92 (1.84-4.74); p < 0.001). We identified several PTSD correlations among individuals quarantined/isolated during the COVID-19 pandemic, including religious practice, reason for quarantine/isolation, education level, and being a case of the infection. These findings can inform worldwide policies to minimize the adverse effects of such social control measures. © 2021 by the author. |
COVID-19; Global survey; Impact of event-scale; Isolation; Mental health; Pandemic; PTSD; Quarantine |
COVID-19; developing world; epidemiology; health worker; mental disorder; psychology; religion; survey method; adult; Article; Asian; controlled study; coronavirus disease 2019; cross-sectional study; female; health care personnel; health survey; human; Impact of Events Scale; major clinical study; male; mental health; multicenter study; pandemic; patient isolation; posttraumatic stress disorder; psychological aspect; quarantine; questionnaire; religion; symptom; vocational education |
MDPI |
16617827 |
|
34073524 |
Article |
Q2 |
747 |
6560 |
|
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