No records
|
853 |
|
7004321762;56149516300;56515300800;56684773900;55744046400;57223591064;55936658000;57200168576;57201460776;8711007700;10738770400;7006103707;56178997200;9839434600;36463148800;7005725866;7401480415;35375758200;7005330161;7003326894;7003577835;57204756458;7005046768;8317854400;57214522941;55581203700;23468829600;35588798700;56294857000;14629925700;57211485705;18233418700;57201154049;57193680596;57207604930;7005187370;36996933500;7007130955;57214142644;57222430080;55910683600;55916025400;56069691500;35425144600;7402478507;7102787520;8782813000;7004964440;7203082725;36626985200;57205643903;55596003100;13605511400;6507487028;55200177800;55813699000;12774189200;57193933353;55290533200;56367717300;12801878400;55551294400;35878929600;7004172232;7006817448;57192991516;57208022691;55694172500;6602686928;57076987400;25930262700;57207538791;8340842300;57201329249;57196546306;8062915000;8967238700;25630585200;8119243000;7006055205;6603206164;7201899612;6507579168;7101773025;55556979000;57200299365;14032698500;16303413000;38361057600;6507479058;6603280645;57205127726;7006089061;57206183278;6506304660;7102991067;23090279300;7006572335;6701838629;7005179997;6602750571;55908358200;56681167700;20435413800;16052066600;23392080000;57220441667;35336030100;7801623093;57192096576;7402885410;35597544800;22950230300;55798182000;57211327735;7202714682;7003401481;55856276500;55550365300;56329994900;7004714937;6507049473;57203045694;35290703600;56704122000;7402570674;35236104200;55875636000;55607151100;7007006986;7004017904;7102874628;57222423611;24472869500;6603112044;6603278141;7404545907;7404545093;55252404400;57222422912;25638539200;6603935912;35167743500;36898273300;6602998309;7103051417;7004111795;7005260014;15123723100;7103077558;7003940149;25627334700;57193926849;6602345929;6603860927;35402464100;57202200403;6603112752;57220809847;57225819403;57202560465;6701734979;9744154400;6603853278;55974377700;24464088800;7202764058;7006309340;7004230524;6506663131;7004990405;6701373204;36102352700;37025474200;7005462362;36627992600;6507768219;22033455700;6602449519;57191377468;56087499100;57200423829;55803547900;7003574538;57188590143;13608163100;57191096172;57160208100;7006698151;35758360000;6603436969;22936794800;7006567136;6507993481;6602267994;55672197200;6603663599;6508232103;7801623963;8245259400;7005325142;6506474236;16174162900;26657184800;57203176429;10040772800;57194029653;15833829500;14010303900;7004648537;7102242981;57200377257;8080068200;57188980475;7003306900;6601994339;6508019002;6602346677;7102664019;21833331400;7005003395;6506383516;7005347938;7401777415;55572079900;14070076100;7004249609;8836917200;7005330750;6508143023;7004075507;56419862800;15761932900;57204346948;54683500300;7005607814;6504349124;36778567400;6508302243;6508201450;12142144800;7401626489;7004586008;7005312089;7006599024;56827216300;55647724000;57223862853;53867898300;24174144200;6602475905;6701915677;44460924300;35089975600;23990157200;6603751860;26540761500;7005253917;45160893200;26431245800;6602378572;6508379996;57201196385;7003861055;7003419958;57220508828;7102026527;8896319000;7103191825;57201157686;7406363066;35598683100;7003269347;56251549600;57222424528;6507924982;7006847998;7003363257;7102774279;24576256200;36702435900;7003378355;20733295200;37025632700;8681535200;22333614900;6602108550;23501185400;14059573000;6701729490;8977254300;14028040000;56364284600;57210517469;36536607500;57222429422;8623408400;55540198300;26643127400;37116407700;57189985796;7004323423;7101759051;7103214591;14321173500;36787471200;8562829600;57222423107;6701760127;7006395298;7003938143;7003987654;57209870082;6506921124;6506658593;22936695200;37760945100;55178458700;7004109937;57216429464;7003351671;7003577988;6603423681;6603046439;55177537100;7003977238;8594051200;6506883072;36052256500;7003841618;7004368559;7102228036;7005059352;26436362200;57208079658;6701512008;14833837700;7004874401;55861380700;57201399856;23468631300;55212537400;55199727100;55637012000;7402910122;55194180800;55215100000;7006142795;35517325300;56548892600;36001158200;22953200100;6508267909;57197035497;22833426900;7402832206;6506579216;35739829200;6602470623;57204340417;6602740949;25121394000;7102295830;6701804811;57222431349;57222425114;55962068500;7005947086;6603127232;6602357797;21742150700;6602386286;6603875390;6602974144;24830456300;24334132900;13604675800;8676551100;57141777400;6701797769;55946425400;57224599697;57200424492;7003650444;9432663300;26533900600;12789310800;7401993822;57219356750;57222423637;56892506300;56049927100;57219724854;9940361100;56469924600;57205471495;55486354000;57197852892;34876303700;57189230909;6508115873;14828589800;6701827497;23972620900;10144314800;55903774100;35478289800;57204676942;57154865000;36988410800;57203334765;55574215994;55125549800;57192613076;57189069436;8428112400;35114530700;8275861900;36061588000;55733375900;57087450700;36077391500;26643378000;34970836400;57188873962;57211010679;55972143800;57193201870;35326139500;57022072800;8161796000;56283020500;36067468100;55705683800;7409487227;57211739037;7404285047;34976376600;7404684682;57196416185;55205682600;56898305700;7404914782;57211683185;7409491627;8612699600;24390784300;7007068344;7102783779;57222429311;26657804700;57222423761;56273345500;8363054200;7101623534;26664094200;50761024500;7101962941;57056480800;57211464807;7003700245;56725088700;55175602400;23049348800;35093684400;7101751727;7103351022;7402094032;55519703500;57203901405;7404345449;55987410700;35083342100;57191447230;56967412600;34767959400;8983355200;7404387261;55006049100;6507858554;7007166025;56526610300;16303137000;7004592650;26643206100;56551716900;7101959716;57202570842;7006404323;56842128500;55477525100;22134170500;57196357192;54790578000;6603672377;20933591700;15519173300;12776641200;7203013829;6507134111;6603423845;57192170309;6701454413;6701683827;56742835300;7102919773;56203158700;7006533543;57222470097;6604095394;7003971612;57209384252;55898268000;57189448178;57203900559;55321345300;7003577067;6602549202;6602479944;7201639444;22233483400;16237813400;55632576000;57218296139;7005588564;55436494000;55233269400;55428291100;55787711900;6602893473;6602435466;7005715704;57204300546;7103129480;57207310850;57219823481;57208624479;57191170791;57216250781;57203006403;57199180909;7801604828;35366034600;6602560687;7201696609;7401512993;56539128600;57220091891;6603176757;57220006681;36195511100;15847493900;26029298300;41861300500;6604061652;56511513500;7101681565;7004903769;35739898300;35450206700;6508041227;55376967300;56918641000;57193518685;24533453400;56377885400;55951401900;6507013291;6602964131;55316015400;7004851347;36096500400;56527345900;7005384908;6603720229;6602296464;8692287800;14824635500;56208382000;8281716700;57202571610;13406489700;36553970600;57202112955;8281285600;7004345457;6504824701;55989756500;37080385200;35510393200;24724046500;6506511166;6602711134;36971192900;57207303624;8855963700;56921114200;57202553907;7102148976;24586622500;7006752944;35597766000;7005961557;7003409065;54383201800;37030758500;56994324400;6603410452;56380605600;30467506200;57191827009;6602478847;26323071000;25421265700;6505760042;36860870100;6602821473;57156322900;30467544400;7004537195;57192363321;6603322255;6603754037;8510264400;6602898063;6701694858;26431307300;57002813700;6508070358;7006551228;7401542858;21639299500;7006426287;53986060400;57191052264;57202678916;57222431597;7005411651;35586143100;7005826945;56270568100;7003715886;6603322371;23024624700;7102629950;57222324574;7007130340;6506067347;35315547600;22333640200;55605766668;7103123723;7004513623;8399860000;23469051600;25640965900;57220762426;7003437032;7006264034;7202172511;7201727799;36120055500;56321083100;56459818800;7102435144;55672763800;19337156800;9844966400;57203241823;26025611500;7101718241;35452100300;35191518900;36551097300;6602953330;57205252508;7005243974;8613979100;57202824158;7005815791;9273846200;57205700292;7006818781;46661817500;14630384900;8382760600;23992261400;7006598166;57200042305;55046823400;7003973196;55133500800;26026890100;7005909792;57194560495;36961880600;8108325500;36888531200;57204787722;7004364572;56444383700;57222210841;7003834413;6603014795;6602912576;7004629537;57204699105;39161190100;7003421807;6701667825;7006342793;6604018654;57032186000;35605675900;15055777000;57202568328;14420866800;8778017400;16505918800;57204871977;56224905600;56519550700;12803894400;57222431966;6602227252;26433344700;8249239000;26423671400;16549616200;57203070093;55261665800;10138966500;38561256800;24467969600;57204717386;36127407400;57222425206;7202319690;57219138746;7006683009;6507474832;7004871138;8756770500;57192072556;57221950687;24168328300;7007180586;35548797500;55250051400;6506198461;57210854589;6506285028;57210095446;7003380926;57200398864;7004508339;7401996221;7402666976;7004036825;7003520802;6603625885;57191279836;6508344275;7006489035;55805783500;9846091700;6602316769;6603962479;7006011445;7004095523;56392936400;57204348625;7004397014;7402656898;7005875504;16306952400;57226214410;7003836678;57223800651;57201013446;7101704422;24281266400;57202568656;8875129500;57205552366;6506514680;7103017890;24722682900;17343413200;56815020500;57195549562;57052990300;55971677900;57216912434;23396694200;6603460714;8695882700;8714612600;6507268479;57207047201;57193724290;56714545700;57222424943;57222431149;57216453888;57222426232;6506184866;35175934800;7102206720;7003613789;6507797157;56013600500;57202363063;14051912800;57210820683;36466414300;35490172600;57218095539;6603761545;7102213066;36608022500;54779603000;57203567401;56625537600;8044086900;7005211977;57204252025;9637693400;55348806500;55240990300;57214113804;57193070957;7005990445;55774503400;9732937200;24067048900;57209634704;22133928800;8937578200;7005604719;53464889100;57201960462;23484838900;6603849613;24390419400;6602311580;6602157821;57211952056;24279369200;7006419894;6603388699;25959086700;14630296200;6505782767;25630363600;7003950005;6505920337;25929961000;24767633500;57219101235;35749664800;57189583307;16444023600;57202555075;7101800543;26643339500;7004492913;57218613674;7003277534;57204452464;57202326657;6507985932;7005166209;57193684292;41761731800;13606279500;57205252690;56018049500;7102840865;7005501700;6507315780;14626301200;6602499751;39761586300;7102880171;57191664897;57199425198;57208456692;57225829929;57200032476;7005747524;57216494781;7005307014;57191967929;7006592133;57202595622;57211164608;56146984600;7201449627;26655578100;6603156811;35223068400;7005397465;26031359500;7006674107;8392377900;35476981500;6701338351;57205253240;55936903900;8967146400;7402496825;55626843000;7404404604;8389277300;55732400800;57205675549;56350180800;57208022952;8763162600;35073936800;57212029637;12805792300;57222425405;7801319908;23496434600;57215380219;7004728052;24402759900;57212756353;7401720519;7005639008;14028289100;57202554603;7006462157;56415556800;7401874111;7202060623;57197782449;56517474200;6507652139;24281198400;26024812600;36079095200;7404174623;36645928100;55884001300;57205571606;57207843968;7006167912;7102589231;6508326397;35596369500;15728981300;7402118353;26422899900;7404942201;7404942218;36707642700;57192007478;56785589800;57202560999;57195974616;56065994500;6603634936;6602403479;7401831302;55259364400;57191419578;26025104700;8615817100;7006748286;56125229000;6504344115;57203026087;6701790107;10939015100;6603207635;55557121100;6603591654;8592206600;56861805100;25027612100;25959633500;57206596771;57188762988;26643419800;7005776723;57202564099;7102688767;57042416300;35952896300;35368696600;55567018400;7004803849;57204716620;36162783500;24597037700;8122092000;16245425400;57204934120;57208769299;35261859600;7402639173;36854408100;56491887400;57219969981;57202558227;9249058700;13007990000;35179620300;23496469800;23027565600;56832994900;55257070900;55988653700;35204939500;57206831542;57201927109;56999574300;55531243000;55251003000;56925618000;57221553704;7103351974;55290553500;34770485900;7402137537;57217503864;49461141600;7006163675;7202996998;7403344587;56266005100;7007150704;57196482749;57193953788;7404626305;26021273500;57208460622;23479983300;56658211800;6603438635;7102778634;7101824269;6603949556;7007107464;35511430300;7102706668;6508093846;6701520075;57197557529;57222426293;56483304300;57202557445;55376306900;6507671335;6602185657;55413938800;56973853700;36935728700;24329481200;8641978400;35583020800;57205857274;56034690500;57203698537;6504197123;36518749600;55204775700;49961552400;14043600600;6505787994;56043234400;7005158360;6507938917;7005260889;57203258271;24332218200;6603794479;57188659150;57226218003;23990763300;6602912807;35561488800;35511536800;6603036900;24341233700;55103704300;57220864200;56597511100;7403475889;57214500274;57222423145;55332022700;55783760700;55733599700;35082061200;34570037700;26633775700;24577511700;57211148209;57208772643;55252373800;16506684100;7003663754;55935566900;57217550125;7405720496;15839283200;6603491822;55906762400;7006881064;7402672765;7101763837;7005382465;7202751145;7202751154;6701631718;55070011800;57219106011;8775569000;15834712300;57008539100;35358575000;7006738404;36105937100;8966469300;6603445254;7005630758;8332986700;6701555878;6603004120;7005022107;6602168910;8325978200;14054198300;10739712300;23982437900;35774260500;7004561085;9276742000;12344914100;57200747577;20734354200;7005234267;34770079100;56277951400;7006704933;12775370900;14037160900;7004026936;7003759426;16068646300;7003421864;54787915800;57206512545;8576581300;36134627100;57213978358;23980321000;7005147380;12809523100;57222430600;6701565491;36723484800;8706090000;56611919200;7005076525;16199442900;15850800300;7005896334;15750897600;57202553986;6602752409;7103061576;6603482374;34876736200;56289487400;35738922700;22953812300;8363214300;35750126400;14054295400;57188565048;56815036900;55538487500;15055970100;57156619800;57215002302;57202561465;36830464200;7409761789;57194632567;35073782800;8632085200;55761799200;57222430431;8886002800;57214428258;57226210464;7601388139;57188860308;7409325415;24776060900;57206876439;7102738946;7005076591;6603239610;57199363473;57104249300;13605341200;6603292662;6507447772;7004050253;57222428122;7102539885;7005205663;7101900613;8622298400;7003793631;7102315993;6603375977;7402598214;6603746477;6603201965;57202558936;16643504800;7102833927;36632427200;7402678479;36192770700;55703085200;7006792171;7202942404;57223412211;6701358510;57203901398;35324880500;7003518239;57191667743;57219932759;55914242300;7202775358;41561551500;8620943000;55015217900;6508125619;36907588200;37085338400;26421679100;7006342832;7102218104;25936382500;7006443207;55671415200;57191517220;57197127203;57226234416;6506181901;26663023500;6603131861;7202692093;36739120600;6603119634;35380287000;7003359642;6701382949;24781257300;23004581200;6602442843;57218181502;57203774832;57202477853;57220768524;57195288915;8605328100;26642587400;6602388770;7102095833;14630663000;57213668350;6701762071;35728685000;57037986000;55665471000;7202206857;7403459177;14068721900;7004175995;6507854410;24067164300;24824907200;7004359623;8410326600;57193382137;24469644800;36876157300;8605487200;6602773646;55436061100;24173303700;57203229916;7401532380;7402002412;7202366755;57226209678;8964920200;34971558000;57226261891;35391955800;6603353572;57195576019;7004854649;7003675930;55811019000;57215758445;7003825057;7004266745;6603492153;57201292804;57222997714;57209509377;56037052400;56582957100;7410160199;57202974838;7406969176;7406966094;7404852882;35280136100;52365588500;57211002757;56414414100;35337365000;44361836000;57201264896;55716905400;56584917000;57200031611;7409119483;57222430195;7601417921;7601414588;57192503364;57220108259;8552515800;56424219700;57203798733;57196847419;6602492426;57201972164;57208900636;57225364943;6603432097;57140263300;8571315000;25225593500;26643193800;57213724980;7005584650;55953045200;8407733400;56323771300;56446881100;13405981900;57208326213;57211728866;25638822000;7402296091;57202910151;26643072100;57129071200;35278554700;57205480625;57207835390;35277037900;57045029800;55807645300;56955898900;37009057700;57250213300;57210097277;55293564700;7404773769;35725555100;57208664270;56056384900;55807349700;56706750100;35741086500;57192490774;57246506000;56604709500;52663832100;57129208600;57202324688;28267766900;14033353800;7102360431;57222427512;55479395700;57200032901;57222428616;11440657800;37031403200;7403027016;55255381600;15839862700;7102099018;55200410600;57210366662;6602874182;56349458900;8541032400;7403692655;57199290159;7501722648;7403967862;7403967446;7404130809;13907342900;57223114799;57188564553;57222429176;55586202400;36768281700;56479446000;57222423840;57211505558;57214232692;7102701262;57208460116;57217002560;7102949426;8879250900;35609639500;57212874148;55053532000;6505833952;56939118400;57188651778;28767739400;37122181000;57091051900;57279881400;56113243500;57202192996;27170235100;56801542200;57210953685;57222427051;57199087668;56471005300;16233590900;55747058200;56739368600;55353457100;56144688800;55635116900;55577932500;57202564424;36077436800;36993952000;55992302400;57203675298;56311720000;7410222218;56333960000;7005328338;57217348857;57208414205;6603581854;54380373000;7005195319;57195483347;56523293400;55206651700;57226208220;57204349429;55240356200;35237632400;8781471300;56089142600;56562876700;57079129900;56336556700;15136008600;12806890800;56041908300;6602220944;7004364721;57209788526;35364781500;56754038800;56141084700;56020727400;57188662075;56962968600;35332392100;7402820975;57202568189;24468250300;7004937006;6602415839;57221797357;56404549800;57413156100;7005329395;57195990523;35513958700;16178208400;6602147668;54941025900;57221580399;57045317800;57202553994;8418167100;57225349322;57208011171;57222431844;7003719722;8884397300;55972196600;56902599300;15849157500;8669618600;57193088923;35731661400;49662079000;57212575721;24778717200;57220045396;7003871202;6602488683;6603167552;6603881796;57204253550;6507247250;26643417600;6603917576;8366932900;57226214445;7201779510;7005032815;6602583044;25422610600;54414535800;35546043800;22135401700;6506604201;6603824898;16492242800;6602545498;22135625400;36604815400;7006064798;6507590295;57189255584;16837168200;57223032437;57202568702;57218261888;57202568208;35478751500;6602443263;8455042900;16025174000;23995351100;25639817100;12775007400;56637208500;7003899981;7102946237;57202561875;56228120200;6602542861;12803767800;6505685876;57204253630;6603859954;57196349635;57202998140;6602345691;36019262100;7003612273;22934831500;57208282442;37077638300;57225842354;57212400057;56990050400;57206904500;6603596955;56841673800;57196054763;6602105053;57202555377;56532913900;56507779900;14010397000;57226211733;25229017300;6505950559;35170622100;11940856200;57202296252;56578563800;6506978724;55507316300;12042560200;35248463800;6701628384;6701419539;55363980700;6603345787;6602813329;6508281360;7004646038;8060210500;7004363088;7103360560;36673325700;23501977200;24781128800;57086647900;37052411100;35105510700;6603195311;23970996500;57222427328;6603848797;56229244600;6505552789;7003635831;9845494000;36464001600;57211993903;35618623400;24765352400;35594792500;56545432400;57204716894;56708477400;57204716532;6603794381;57204645120;7003606185;35496106100;56269393600;55892485800;8833710300;7003907936;6701385062;54383568800;7102443487;55588597300;57221928190;57203763101;10340035200;57202561134;25422321000;57201589494;7004531835;35501091500;57215280910;57190088984;6603284622;57222430044;57212111326;55619312293;7404226820;24341743600;23470029300;36797408600;16402446200;35242985300;55314279400;55588828400;55413407900;7406290033;57222426937;7006620728;57223952906;57217457900;37034594600;57218466685;35975058600;57214220793;57190124353;14066618900;35332620200;7003786486;35776846400;23501748900;7402386495;24824806600;35449589100;7402876712;57222425707;7402094700;55559759300;57208450343;7006933381;7006816473;57208450542;57205609490;57195918724;57222431526;19435505300;6603156033;6506448361;56986753100;7004202353;57203868144;7004266593;57194327910;6602579087;57226205850;55358195400;7102700434;7003797796;56652458100;57190977458;57188971988;56617027800;7404471229;8677868300;7102775305;57193076465;35148038500;7004238296;57202252338;56972645200;57221237227;57189032411;9839069000;25825519000;57192977071;12796040000;55658118800;6701581292;11840418600;57214211749;6508355042;24338705300;55535260300;57204307693;6602332720;39262401200;57195905627;6701611153;16550243700;57191475440;57222429053;55794077300;55911314100;56070407600;55500343900;36673529800;6701563312;7003919683;55164681200;57226200184;55211690100;6507420371;7402698214;55809207900;7102236010;26646883000;6507498358;56242626700;55621554100;6603220523;7202146678;36894024100;6602875797;7102713833;55789294700;6602563944;8337876100;57203704573;56611569000;16245914100;6603382595;57196263269;8605149500;7007044186;21834414500;7006471717;56379808700;14520719800;57200814289;57202844800;6602163840;36515310600;57203745023;57196980063;23486672400;7005413542;35378641700;57189021997;35376235400;7202067341;8911840400;56769002700;7006051880;6507247697;57222429264;57218336396;25123509600;56587365700;8414744700;46062251900;57213906081;55240364700;57073053300;24385391500;7202850330;7006148623;36523779300;6603341244;14034745300;7102746041;55776621300;24473454000;7402500250;57190284281;55736757100;57210922447;8637424300;7003712969;55106936600;57204338438;55646570700;6602765251;57210391706;57204550887;57216429164;57216934875;57199844120;6701360547;24462445900;35273307900;7004819803;23029028400;7003716875;7007056663;7404103233;57216555148;9235700400;7403229808;6508125545;56428844500;57202564971;7403904799;7005392847;7005419880;6507628443;26321752500;6701781359;6507190476;8843282300;57212263398;57194691493;57172268300;57222422810;55840385800;16417422400;36892113200;56324007400;26030541600;6506621611;57211793163;7006537951;7202452886;6701826869;7003514088;7005456155;55324964200;8105991000;35293245600;6507801380;55109213000;7102665889;41762122900;57189106913;56850147000;6602377502;35488909100;6603272811;8692047100;57196601765;35912423800;7006106186;16302045500;55811329100;35752476600;57222422719;35285977200;34877480900;22234651200;7006379715;57203082700;15766207800;55175013400;6506921126;57203025267;11339375000;55791118200;8525592400;26026041200;57211768525;56176517500;57223193486;57193653008;57226200581;57191674610;7501832226;7006174482;56464373300;56086360200;57000071300;8514343200;55575722800;7201451563;57204059919;6506521012;6603408167;7007015511;9042283100;57218666033;7103299061;6507770610;56136926300;55708770400;7005552423;57203353711;56249903500;57207806670;55897284500;35467863000;57222641286;50162140900;55600528200;7005988619;56088311400;27467782400;10939510100;14629192800;24481938000;7004626121;57201656356;57203561030;7007144223;57205295682;57204887138;57205295603;14825770000;37361475000;8719498800;55643146900;55347340900;24482104800;57189902034;6701827394;6602114306;8058298400;6603201503;57195718086;57204538162;6602849305;7003742774;57203833094;57221435562;7004083405;57218096035;7003366639;55349706300;24067351600;35597536700;35094404400;57204674259;35273059900;6701815819;8837168500;57203606367;35551105600;26533077300;57202571306;23668630800;6701411451;7006039454;15760830500;55212090500;57226204442;55989684500;56801074300;57189327456;7201351734;10044553500;35476433300;57202642902;6602675035;25825436400;7007112965;57204901419;55974281000;57202595853;6603128353;7006929886;6603688572;57202595337;6506394583;36509017500;12041563600;57218125712;57222429847;24172704600;57218118740;23035927500;57200709657;6508390740;6602144137;7005083571;57202568526;57211501630;57210397215;7004402909;15061646700;6701536124;23668342500;6603650460;56906085600;57202846025;57211074975;7102612805;6701576100;23393885200;35311870000;9845809100;57195235358;35249229600;36599178400;56892756600;6701411802;24341605300;54929860200;57203743295;6701632965;37038328000;6602133625;6603885445;35557757100;6507600092;15021428500;57209054753;6602623536;36994065800;36464211300;57211729940;56660723900;7005610377;56428966400;7005427326;6506945686;57211868023;57210225043;56429558100;35556435200;7103409088;57207306560;57213427131;57218184972;7004110913;8511467500;57202572390;55351780600;7005289262;57217067093;57219816673;57193804154;6701653499;7006192678;6602729201;57201060203;57217064300;8510061300;15840545200;6602191975;56013600800;7005566715;57222429666;35976808200;7005764407;7004016032;23012667500;7101824161;36188495500;36785454500;57195723226;6602419075;24462293600;56912924400;6602557695;6508365316;55259853000;57225390900;7005864634;57200693799;56437903500;7402433182;57208764500;16048120500;7103057927;24069085200;57145839200;6506696165;7004208746;7201740644;6701396024;56024481800;9237176700;57211212021;57202561036;23019844600;55350355800;8964506700;57225825577;57226218407;57214815557;8600540600;57222993977;7201820903;7202685370;57191862269;14052955700;7005064608;57205016765;57191894113;35370679900;55360329300;7003424909;35084317100;25960364400;26639699900;35916636300;16175956300;52464404100;55987640100;55233483500;15758262300;57214321480;7403476299;25926132100;7003280106;7005243249;56971443500;26026482100;7006777497;16204129000;8266997600;55408004100;55607247200;13611914400;57202355226;7006653510;22981730000;57209855807;39561545200;57219190031;36868342700;7102001749;57203214290;6508083352;22136421100;57215985586;8635745600;57211794466;57208494471;55986083800;57222422975;6508073684;56497964400;57222429333;6505686544;57205372589;57226228770;6603243029;57202572414;7102634392;8765404500;7004486352;7006536447;7003369158;24825305600;7003323304;6602582130;7005198391;7003594224;16053215200;7201439267;8966965800;57220100510;36186064200;7402385294;16025287800;57198433168;9435662900;57190740913;57223018270;55536838900;7004475293;57196232596;57204594132;57214590668;6603410568;57202843193;26041151700;9535214700;57161891200;57219190707;7006237300;9743302900;57192085535;56370214300;56074360100;57202594829;8870626000;57209639732;56018401600;57215692681;57202595308;7003935450;7102013428;6505914322;57206332025;12545373100;57200035853;54968898300;6508233291;6603068109;6504691421;8619095100;7003889076;56346402100;57204578003;55107372900;57195914548;7102817023;57200846304;26030668200;22938928200;55435535500;57208426712;7402096678;57202573033;55588702100;56404761400;57207825891;7404929947;55258119100;23487035900;56430243800;7005472757;55598477700;7202787527;13808169500;9334781100;36124042300;55355312500;57225085472;14833233900;7403432610;57027783700;7102999102;26531914500;56060914900;7006636332;15760855300;55407870200;55220384300;7203086832;57193704088;55574205762;55257279800;56521225300;7201954853;56211615300;57193616419;41961862500;56276434500;57224875679;36451325800;57203806970;57202560450;7005155732;18042899100;57208849868;7201538823;57202380075;7202268448;8320879800;57206711797;35241320700;8093458600;57208796804;35238845500;57200693533;14036392300;57202564009;7004158254;57226214299;7006108935;6505977427;8987563900;6602583688;6701699185;56173046800;57173366200;57209054705;57222432428;57193196069;7006081443;7003724048;6507584200;7005803942;6603341737;16417750700;57205232177;12243092000;7404037299;57212404443;13103999700;55614665300;23502273000;7004337251;6701770003;34875742300;55654449000;57222431748;57220877421;56920290800;8610075900;8069222600;6507949155;56209127200;56481706500;23101365600;6508123582;57222425181;57202289820;57202963715;57204366050;7006799065;57215471576;8559438900;57211248593;57203078630;6701595022;15926509000;16025646900;57202595493;6701350974;16317750200;55255669500;55019255100;57191629208;7004247427;12795503900;57194214707;23487247900;7006682075;57224870762;57193848308;57193165289;57284898700;55845419074;55541960000;55231749800;57227815900;7404239815;55189524900;7003495988;6602464922;7005070026;57218118213;57222424537;7102740079;23482617000;6507210517;25927523600;24492392800;6602670880;57197791014;57209726516;7005854418;57189024051;7006613318;55628561761;55756575000;25932332600;57195313915;57193488434;6506248323;36093620600;56457100900;57222429302;56844151200;7406340423;55502217500;8414610300;35365464900;7401988863;56922504400;57200856202;7004207770;6506172002;20035582600;7405892475;14520055300;24482187000;6507870162;6603874946;7003818981;6508226147;7006354794;57205252201;55014397500;6506386892;6602925840;7005619431;6701764930;57200906584;6603769366;24175264100;57211206819;6603960408;54994151700;57193551879;7404654081;26036861700;57226204196;16064985200;57225726426;57207896602;36991419100;12040738200;7003806282;7005701652;35581944100;6506052249;8316455400;7005701629;57189617828;55262078800;6506521126;36057468900;57109953200;7202716216;36708779100;57206834640;6602617647;7201965582;57205463885;6701387914;56485488700;6701662650;7004288600;7004516866;7003839205;57199391897;7006342801;57207829313;57200958877;57202379480;7005956550;57223024840;7006070805;55118582000;57222643653;26424467100;9275641000;55988721700;7003383220;6701327333;7007002599;7007025347;7401858661;6603164134;7202101465;36761888300;56922430500;46462235200;7004612677;55372420800;12793129300;57212334378;7003458646;57223118665;6602677258;57170709400;36574397300;7005768480;6603645752;7005869334;57210808951;57202561885;57205522465;36553581600;55550397800;7102885592;57215741522;57211464143;35207035500;7006402578;14833515300;8577923700;6603186020;8546362100;6701740203;23669417000;55188659100;15749629800;57079961200;57219956383;56216015900;57216575008;57193925684;6602696654;57207943932;57194558034;7006478965;57189996037;6602976996;7102102458;6701380393;7005406744;24072644900;6603326982;6701641490;57197167733;6602697545;54891603500;6505759335;55030597000;55256134800;57217322974;56176991200;57225361429;57208766754;57222423380;6602829836;56640911000;57210732447;7004431206;34573906500;7006140105;57191835167;7007150708;57205685014;24353921800;57205490307;6701444514;6506463691;6602315726;22636235400;6603569792;7801582270;7006874326;25655476600;57192368240;57205254042;6602835614;7004168416;35333082000;6603463193;7004181533;57189003725;7005226476;57201929616;34974875300;7403745422;57207902741;7004250810;57216234813;57133939300;55778098800;9845836100;57205371196;57210083425;57211761927;56537154400;57208612551;57209624032;23494114200;56259412600;55863432900;57222431635;35231432500;57224552032;35331263700;37108687700;56184960100;57071987800;13410389100;57192089816;55596673500;57218664689;57188965524;56141652900;56230335900;57221237519;57226066623;15077601500;57210072740;57222432737;55925703800;55625167500;37103075800;37084642900;35235510300;55991788600;7601510564;57219360353;56389498500;37118069300;57207001349;18234405600;56004292500;57192244543;57225088568;47861528800;17636798000;56806876600;57084394800;10045073600;57195338514;8618136100;35476293400;7005212676;8912981500;7402516910;35774505000;7202664519;8449342800;6602976119;6602306881;8917866100;7004155039;7202097826;57008762500;57199840632;57189727404;57188855429;7004330121;55666474000;8592831600;36520238700;24464498500;7004081585;57173661900;7004563027;36090521300;57203074071;56922656500;7203003437;7501535354;6603255079;56798211200;7102589252;6602254642;12140970200;57212669723;57193163639;34874358200;13007985800;8541929000;56535537000;49864723900;7501665750;57202555203;57221514090;7404512056;57198542876;56018221600;57206257932;55533104300;7407184569;18345422600;57222665159;55715080200;15137345100;55883095700;7006636647;8941692200;57222422451;7402151748;55577346500;57200903801;7004985186;7102629470;55633139100;7201917080;57210071644;30567976200;56673268600;57222423109;57215026464;35222605100;57196354575;57202571562;35312960300;56325480500;57218613989;7402267200;12781377100;55965394000;57222430583;7407449714;57191164987;7408553914;57188646143;57221719949;57203374258;57202521756;56274538300;35473744200;55712028800;7403509382;7005763172;55928095100;7401745087;7402519624;57226263441;55992110000;7404800601;57219829416;35249587600;57209055653;12445064900;57212326313;55719585400;55732894600;57216807882;57200826079;56402003700;57209626994;57141315700;56379207500;7408518510;55501058100;55501081100;7406497958;55147781500;57212539570;57206630280;56496093900;7402471873;57195659515;36062099400;55588377000;55279661300;26665153800;7201991060;55194826600;57217002087;7403273786;57193903631;57189323801;17136606400;14038535500;7101665539;57205073455;57219366435;34877874000;56498694300;7006810223;55661388000;57222424335;57188969739;57226895324;57211813320;23487437700;7404272543;7405732354;57193984455;57203966468;16053881600;56991716400;57201137908;9942981700;57222432698;7403272971;36919510400;12545498400;7101875828;56364893100;9238000400;7005594279;57209240490;57004888400;24082112300;6701889077;7003942649;6507791461;25423464300;7004137343;22837329300;26535357300;55200686700;7005839455;57189902371;57195572210;7003562086;24460757000;57200629519;74 |
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 |
2021 |
Autophagy |
17 |
1 |
|
1 |
382 |
|
312 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102619204&doi=10.1080%2f15548627.2020.1797280&partnerID=40&md5=32bc24d3ffd8e3f626d0d619cf3a8fc8 |
|
|
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field. © 2020 Informa UK Limited, trading as Taylor & Francis Group. |
Autophagosome; cancer; flux; LC3; lysosome; macroautophagy; neurodegeneration; phagophore; stress; vacuole |
adenylate kinase; atg16l1 protein; autophagy related protein; autophagy related protein 14; autophagy related protein 18; autophagy related protein 5; autophagy related protein 8 family; beclin 1; biological marker; dfcp1 protein; DNA; gamma interferon; green fluorescent protein; mammalian target of rapamycin; nanoparticle; phosphatidylinositol 3 kinase; protein; RNA; sequestosome 1; serine threonine protein kinase ULK1; SNARE protein; sphingolipid; stx17 protein; tecpr1 protein; ubiquitin; unclassified drug; aggrephagy; apicoplast; assay; autophagosome; autophagy (cellular); bimolecular fluorescence complementation; Caenorhabditis elegans; cell death; cell nucleus; cell stress; cell vacuole; chlorophagy; chromatophagy; clockophagy; crinophagy; data base; doryphagy; Drosophila melanogaster |
Taylor and Francis Ltd. |
15548627 |
|
33634751 |
Review |
Q1 |
3934 |
400 |
|
|
855 |
Syahrul S., Maliga H.A., Ilmawan M., Fahriani M., Mamada S.S., Fajar J.K., Frediansyah A., Syahrul F.N., Imran I., Haris S., Rambe A.S., Emran T.B., Rabaan A.A., Tiwari R., Dhama K., Nainu F., Mutiawati E., Harapan H. |
57216064819;57222334227;57217182580;57219947648;57211891425;56156139600;56897210000;57222337525;56589826700;57222343545;57193757980;55325267100;56049830800;55314856100;6507396956;57120069200;56652288600;55844857500; |
Hemorrhagic and ischemic stroke in patients with coronavirus disease 2019: Incidence, risk factors, and pathogenesis - a systematic review and meta-analysis |
2021 |
F1000Research |
10 |
|
34 |
|
|
|
12 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102340647&doi=10.12688%2ff1000research.42308.1&partnerID=40&md5=8cfb8151ce9b8e51bb3ec5847e7a2ca5 |
Department of Neurology, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, 23111, Indonesia; Department of Neurology, Dr. Zainoel Abidin Hospital, Banda Aceh, Aceh, 23111, Indonesia; Faculty of Medicine, Universitas Brawijaya, Malang, East Java, 65117, Indonesia; Medical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, 23111, Indonesia; Faculty of Pharmacy, Hasanuddin University, Makassar, South Sulawesi, 90245, Indonesia; Brawijaya Internal Medicine Research Center, Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, East Java, 65145, Indonesia; Research Division for Natural Product Technology (BPTBA), Indonesian Institute of Sciences (LIPI), Wonosari, 55861, Indonesia; Department of Neurology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Department of Neurology, Faculty of Medicine, Universitas Sumatera Utara, Medan, North Sumatra, 20155, Indonesia; Department of Pharmacy, BGC Trust University Bangladesh, Chittagong, 4381, Bangladesh; Molecular Diagnostic Laboratory, Johns Hopkins Aramco Healthcare, Dhahran, 31311, Saudi Arabia; Department of Veterinary Microbiology and Immunology, College of Veterinary Sciences, UP Pandit Deen Upadhayay Pashu Chikitsa Vigyan Vishwavidyalay Evum Go-Anusandhan Sansthan (DUVASU), Mathura, Uttar Pradesh, 281 001, India; Division of Pathology, ICAR-Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh, 243122, India; Department of Microbiology, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, 23111, Indonesia; Tropical Disease Centre, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, 23111, Indonesia |
Syahrul, S., Department of Neurology, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, 23111, Indonesia, Department of Neurology, Dr. Zainoel Abidin Hospital, Banda Aceh, Aceh, 23111, Indonesia; Maliga, H.A., Faculty of Medicine, Universitas Brawijaya, Malang, East Java, 65117, Indonesia; Ilmawan, M., Faculty of Medicine, Universitas Brawijaya, Malang, East Java, 65117, Indonesia; Fahriani, M., Medical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, 23111, Indonesia; Mamada, S.S., Faculty of Pharmacy, Hasanuddin University, Makassar, South Sulawesi, 90245, Indonesia; Fajar, J.K., Faculty of Medicine, Universitas Brawijaya, Malang, East Java, 65117, Indonesia, Brawijaya Internal Medicine Research Center, Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, East Java, 65145, Indonesia; Frediansyah, A., Research Division for Natural Product Technology (BPTBA), Indonesian Institute of Sciences (LIPI), Wonosari, 55861, Indonesia; Syahrul, F.N., Department of Neurology, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, 23111, Indonesia; Imran, I., Department of Neurology, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, 23111, Indonesia, Department of Neurology, Dr. Zainoel Abidin Hospital, Banda Aceh, Aceh, 23111, Indonesia; Haris, S., Department of Neurology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Rambe, A.S., Department of Neurology, Faculty of Medicine, Universitas Sumatera Utara, Medan, North Sumatra, 20155, Indonesia; Emran, T.B., Department of Pharmacy, BGC Trust University Bangladesh, Chittagong, 4381, Bangladesh; Rabaan, A.A., Molecular Diagnostic Laboratory, Johns Hopkins Aramco Healthcare, Dhahran, 31311, Saudi Arabia; Tiwari, R., Department of Veterinary Microbiology and Immunology, College of Veterinary Sciences, UP Pandit Deen Upadhayay Pashu Chikitsa Vigyan Vishwavidyalay Evum Go-Anusandhan Sansthan (DUVASU), Mathura, Uttar Pradesh, 281 001, India; Dhama, K., Division of Pathology, ICAR-Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh, 243122, India; Nainu, F., Faculty of Pharmacy, Hasanuddin University, Makassar, South Sulawesi, 90245, Indonesia; Mutiawati, E., Department of Neurology, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, 23111, Indonesia, Department of Neurology, Dr. Zainoel Abidin Hospital, Banda Aceh, Aceh, 23111, Indonesia; Harapan, H., Medical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, 23111, Indonesia, Department of Microbiology, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, 23111, Indonesia, Tropical Disease Centre, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, 23111, Indonesia |
Background: In this study, we aimed to determine the global prevalence, chronological order of symptom appearance, and mortality rates with regard to hemorrhagic and ischemic stroke in patients with coronavirus disease 2019 (COVID-19) and to discuss possible pathogeneses of hemorrhagic and ischemic stroke in individuals with the disease. Methods: We searched the PubMed, Scopus, and Web of Science databases for relevant articles published up to November 8, 2020. Data regarding study characteristics, hemorrhagic stroke, ischemic stroke, and COVID-19 were retrieved in accordance with the PRISMA guidelines. The Newcastle-Ottawa scale was used to assess the quality of the eligible studies. The pooled prevalence and mortality rate of hemorrhagic and ischemic stroke were calculated. Results: The pooled estimate of prevalence of hemorrhagic stroke was 0.46% (95% CI 0.40%-0.53%; I 2 =89.81%) among 67,155 COVID-19 patients and that of ischemic stroke was 1.11% (95% CI 1.03%-1.22%; I 2 =94.07%) among 58,104 COVID-19 patients. Ischemic stroke was more predominant (incidence: 71.58%) than hemorrhagic stroke (incidence: 28.42%) in COVID-19 patients who experienced a stroke. In COVID-19 patients who experienced a stroke, hospital admission with respiratory symptoms was more commonly reported than that with neurological symptoms (20.83% for hemorrhagic stroke and 5.51% for ischemic stroke versus 6.94% for hemorrhagic stroke and 5.33% for ischemic stroke, respectively). The pooled mortality rate of COVID-19 patients who experienced a hemorrhagic and ischemic stroke was 44.72% (95% CI 36.73%-52.98%) and 36.23% (95% CI 30.63%-42.24%), respectively. Conclusions: Although the occurrence of hemorrhagic and ischemic stroke is low, the mortality rates of both stroke types in patients with COVID-19 are concerning, and therefore, despite several potential pathogeneses that have been proposed, studies aimed at definitively elucidating the mechanisms of hemorrhagic and ischemic stroke in individuals with COVID-19 are warranted. PROSPERO registration: CRD42020224470 (04/12/20) © 2021 Syahrul S et al. |
COVID-19; Haemorrhagic stroke; Ischemic stroke; Meta-analysis; Pathogenesis; SARS-CoV-2; Systematic review |
Article; brain hemorrhage; clinical feature; clinical outcome; coronavirus disease 2019; hospital admission; human; incidence; ischemic stroke; meta analysis (topic); mortality rate; neurologic disease; Newcastle-Ottawa scale; pathogenesis; pooled analysis; Preferred Reporting Items for Systematic Reviews and Meta-Analyses; publication bias; respiratory tract disease; risk factor; statistical analysis; symptom; systematic review; brain ischemia; complication; incidence; meta analysis; prospective study; retrospective study; risk factor; Brain Ischemia; COVID-19; Humans; Incidence; Ischemic Stroke; Prospective Studies; Retrospective Studies; Risk Factors |
F1000 Research Ltd |
20461402 |
|
33708378 |
Article |
Q1 |
1099 |
3793 |
|
|
883 |
Harimurti K., Saldi S.R.F., Dewiasty E., Alfarizi T., Dharmayuli M., Khoeri M.M., Paramaiswari W.T., Salsabila K., Tafroji W., Halim C., Jiang Q., Gamil A., Safari D. |
23473513200;55201904000;55257705500;57221853325;57221841113;55994827400;57221097580;57192272141;57118271600;57221850899;36028184700;57202388319;23493586700; |
Streptococcus pneumoniae carriage and antibiotic susceptibility among Indonesian pilgrims during the Hajj pilgrimage in 2015 |
2021 |
PLoS ONE |
16 |
1 January |
e0246122 |
|
|
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100423019&doi=10.1371%2fjournal.pone.0246122&partnerID=40&md5=49970f6f2918134dc220f4fd13977bed |
Clinical Epidemiology and Evidence-Based Medicine (CEEBM) Unit, Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Internal Medicine, Faculty of Medicine Universitas Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Center of Hajj Health, Ministry of Health, Jakarta, Indonesia; Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Pfizer Indonesia, Jakarta, Indonesia; Pfizer Inc., Collegeville, PA, United States; Pfizer Inc., Emerging Markets Medical and Scientific Affairs, Dubai, United Arab Emirates |
Harimurti, K., Clinical Epidemiology and Evidence-Based Medicine (CEEBM) Unit, Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Saldi, S.R.F., Clinical Epidemiology and Evidence-Based Medicine (CEEBM) Unit, Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Dewiasty, E., Clinical Epidemiology and Evidence-Based Medicine (CEEBM) Unit, Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Alfarizi, T., Center of Hajj Health, Ministry of Health, Jakarta, Indonesia; Dharmayuli, M., Center of Hajj Health, Ministry of Health, Jakarta, Indonesia; Khoeri, M.M., Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Paramaiswari, W.T., Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Salsabila, K., Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Tafroji, W., Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Halim, C., Pfizer Indonesia, Jakarta, Indonesia; Jiang, Q., Pfizer Inc., Collegeville, PA, United States; Gamil, A., Pfizer Inc., Emerging Markets Medical and Scientific Affairs, Dubai, United Arab Emirates; Safari, D., Eijkman Institute for Molecular Biology, Jakarta, Indonesia |
The Hajj is an annual pilgrimage to Mecca and one of the largest gathering of people in the world. Most Indonesian pilgrims are senior adults and elderly adults, who are more prone to acquire infections during the Hajj ritual. The aims of this study are to investigate the dynamics of Streptococcus pneumoniae colonization and to investigate antibiotic susceptibility of pneumococcal strains in Indonesian pilgrims. This was a prospective multi-site longitudinal study in Indonesian hajj pilgrims aged >18 years old in the year 2015. Nasopharyngeal swabs were collected from the same subject before departure and upon arrival at the airport. S. pneumoniae was identified using conventional and molecular approach, while antibiotic susceptibility was determined using a disk diffusion method. Among 813 Hajj pilgrims who were enrolled from five sites in this study, the prevalence of S. pneumoniae carriage rates before- and after-the Hajj were 8.6% (95% CI 6.7–10.5%) and 8.2% (95% CI 6.4–10.1%), (p value: 0.844) respectively. Serotype 16F, 6A/6B, 3, 18, and 23F were the five most prevalent serotypes before Hajj, whereas serotypes 3, 34, 13, 4, and 23F were the most prevalent serotypes after Hajj. Serotype 3 was identified as most acquired serotype during Hajj in Indonesian pilgrim. There was an increase in the percentage of isolates susceptible to co-trimoxazole after Hajj (42.9% versus 57.4%). The study provided an overview of the change of dynamics of S. pneumoniae serotype acquisition in Indonesian Hajj Pilgrims. Along with data of vaccination serotypes coverage and antimicrobial susceptibility, these findings may contribute to recommendation of vaccination and treatment policies in the future. © 2021 Harimurti et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
|
chloramphenicol; clindamycin; cotrimoxazole; erythromycin; penicillin derivative; tetracycline; antiinfective agent; adult; airport; antibiotic sensitivity; Article; bacterial colonization; bacterial strain; bacterium isolate; controlled study; disk diffusion; female; human; Indonesian; longitudinal study; male; nasopharyngeal swab; nonhuman; prospective study; serotype; Streptococcus pneumoniae; adolescent; antibiotic resistance; clinical trial; crowding (area); growth, development and aging; heterozygote; Indonesia; isolation and purification; microbial sensitivity test; microbiology; middle aged; multicenter study; nasopharynx; pneumococcal infection; Streptococcus pneumoniae; Adolescent; Adult; Anti-Bacterial Agents; Carrier State; Crowding; Drug Resistance, Bacterial; Female; Humans; |
Public Library of Science |
19326203 |
|
33497410 |
Article |
Q1 |
990 |
4434 |
|
|
885 |
Prayitno A., Supriyatno B., Munasir Z., Karuniawati A., Hadinegoro S.R.S., Prihartono J., Safari D., Sundoro J., Khoeri M.M. |
57193342301;37068046400;7801694370;54886816200;57226218772;6602605635;23493586700;49762130000;55994827400; |
Pneumococcal nasopharyngeal carriage in Indonesia infants and toddlers post-PCV13 vaccination in a 2+1 schedule: A prospective cohort study |
2021 |
PLoS ONE |
16 |
1 January |
e0245789 |
|
|
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100392996&doi=10.1371%2fjournal.pone.0245789&partnerID=40&md5=cb78eb658b86a8f3be7a35fe8b7fd3cc |
Department of Pediatrics, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Microbiology, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Community Medicine, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Molecular Bacteriology, Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Indonesian Technical Advisory Group on Immunization, Jakarta, Indonesia |
Prayitno, A., Department of Pediatrics, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Supriyatno, B., Department of Pediatrics, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Munasir, Z., Department of Pediatrics, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Karuniawati, A., Department of Microbiology, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Hadinegoro, S.R.S., Department of Pediatrics, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Prihartono, J., Department of Community Medicine, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Safari, D., Molecular Bacteriology, Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Sundoro, J., Indonesian Technical Advisory Group on Immunization, Jakarta, Indonesia; Khoeri, M.M., Molecular Bacteriology, Eijkman Institute for Molecular Biology, Jakarta, Indonesia |
Background The PCV13 immunization demonstration program began in October 2017 in Indonesia. The aim of this study is to assess the dynamic changes of pneumococcal serotype before and after PCV13 administration, with two primary and one booster doses. Methods The prospective cohort study was conducted as a follow up study measuring the impact of PCV13 demonstration program by the Indonesian Ministry of Health in Lombok Island, West Nusa Tenggara, Indonesia, from March 2018 to June 2019. The subjects were two-month-old healthy infants who were brought to the primary care facility for routine vaccination and followed until 18 months of age. We use convenience sampling method. There were 115 infants in the control group and 118 infants in the vaccine group, and the PCV immunization was given on a 2+1 schedule. Nasopharyngeal (NP) swabs were collected four times during the vaccination periods by trained medical staff. Specimens were analyzed by culture methods to detect S. pneumonia colonization and multiplex polymerase chain reaction (mPCR) to determine serotype. The most frequently detected serotypes will be named as dominant serotypes. Descriptive analysis of demographic characteristics, the prevalence of overall and serotype colonization, and the distribution of serotypes were performed. The prevalence of both cohort groups were compared using chi-square test. Statistical significance was set at p < 0.05. Results Two hundred and thirty three infants age two months old were recruited, with 48.9% of the subjects were male and 51.1% of the subjects were female. Sociodemographic data in both cohort groups were relatively equal. Nasopharyngeal pneumococcal colonization before PCV13 administration occurred in 19.1% of the control and 22.9% of the vaccine group. The prevalence increased with increasing age in both groups. The prevalence of VT serotypes in control groups aged 2 months, 4 months, 12 months, and 18 months was 40.9%, 44.2%, 53.8%, and 54.3%, respectively, and in the vaccine group, 25.9%, 40.4%, 38.0%, and 22.6%, respectively. The most common VT serotypes in both groups were 6A/6B, 19F, 23F, and 14. The prevalence of VT serotypes decreased significantly compared to non-vaccine type serotypes after three doses of the PCV13 vaccine (p < 0.001). Another notable change was the decline in prevalence of serotype 6A/6B after PCV13 administration using the 2+1 schedule. Conclusions This study shows lower prevalence of VT and 6A/6B serotypes in the nasopharynx among children who were PCV13 vaccinated compared with those who were unvaccinated. The result from this study will be the beginning of future vaccine evaluation in larger population and longer period of study. © 2021 Prayitno et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
|
Pneumococcus vaccine; 13-valent pneumococcal vaccine; Pneumococcus vaccine; Article; bacterial colonization; bacterium carrier; cohort analysis; controlled study; demography; female; follow up; human; human experiment; Indonesia; infant; male; multiplex polymerase chain reaction; nasopharynx; normal human; population research; prevalence; primary medical care; serotype; sex ratio; social status; Streptococcus pneumoniae; toddler; trend study; vaccination; immunology; isolation and purification; microbiology; nose mucosa; pathogenicity; pneumococcal infection; preschool child; procedures; Streptococcus pneumoniae; Child, Preschool; Female; Humans; Indonesia; Infant; Male; Nasal Mucosa; Pneumococcal Infections; Pneumococcal Vaccines; Streptococcus pneumoniae; Vaccination |
Public Library of Science |
19326203 |
|
33497405 |
Article |
Q1 |
990 |
4434 |
|
|
888 |
Subekti I., Kartiko G.J., Suhardi Z.F., Muhadi, Wisnu W. |
24336854300;57221818935;57221814580;57189615533;57200425452; |
Serum TSH level as predictor of Graves' disease recurrence following antithyroid drug withdrawal: A systematic review |
2021 |
PLoS ONE |
16 |
1 January |
e0245978 |
|
|
|
1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100298149&doi=10.1371%2fjournal.pone.0245978&partnerID=40&md5=68971152ed2933aff2d374d62012a231 |
Faculty of Medicine, Division of Endocrinology and Metabolism, Department of Internal Medicine, Dr. Cipto Mangunkusumo General Hospital, Universitas Indonesia, Jakarta, Indonesia; Faculty of Medicine, Department of Internal Medicine, Dr. Cipto Mangunkusumo General Hospital, Universitas Indonesia, Jakarta, Indonesia; Faculty of Medicine, Division of Cardiology, Department of Internal Medicine, Dr. Cipto Mangunkusumo General Hospital, Universitas Indonesia, Jakarta, Indonesia |
Subekti, I., Faculty of Medicine, Division of Endocrinology and Metabolism, Department of Internal Medicine, Dr. Cipto Mangunkusumo General Hospital, Universitas Indonesia, Jakarta, Indonesia; Kartiko, G.J., Faculty of Medicine, Department of Internal Medicine, Dr. Cipto Mangunkusumo General Hospital, Universitas Indonesia, Jakarta, Indonesia; Suhardi, Z.F., Faculty of Medicine, Department of Internal Medicine, Dr. Cipto Mangunkusumo General Hospital, Universitas Indonesia, Jakarta, Indonesia; Muhadi, Faculty of Medicine, Division of Cardiology, Department of Internal Medicine, Dr. Cipto Mangunkusumo General Hospital, Universitas Indonesia, Jakarta, Indonesia; Wisnu, W., Faculty of Medicine, Division of Endocrinology and Metabolism, Department of Internal Medicine, Dr. Cipto Mangunkusumo General Hospital, Universitas Indonesia, Jakarta, Indonesia |
Graves' disease (GD) has a high recurrence rate despite various and adequate treatment. Numerous studies have been performed to identify the predictor of disease recurrence. This report aims to investigate the role of thyroid stimulating hormone (TSH) level as a thyrotropin in predicting the recurrence of Graves' disease within 1 to 2 years following antithyroid drug (ATD) withdrawal. Literature searching was conducted on PubMed, Scopus, Cochrane, Proquest, EBSCO in August 2019 and Google Scholar in October 2020. The study criteria include the study that evaluates TSH level 4 weeks following ATD withdrawal, with subjects ≥18 years old who are retrospectively or prospectively followed up after 1 to 2 years following ATD withdrawal. Four eligible studies were selected based on inclusion/exclusion criteria, all of which measured TSH level at 4 weeks following ATD withdrawal. All studies had 1 to 2 years follow up. One study was an RCT, two studies were done in prospective cohort and another in retrospective cohort. All studies had comparable validity and applicability. Three out of four studies suggested that low TSH level measured 4 weeks following treatment withdrawal was associated with higher risk of disease recurrence. In conclusion, low TSH level obtained 4 weeks after ATD withdrawal was associated with higher rate of recurrence rate in GD. Copyright: © 2021 Subekti et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
|
antithyroid agent; thyrotropin; antithyroid agent; thyrotropin; Article; clinical evaluation; clinical outcome; disease association; drug withdrawal; follow up; Graves disease; human; prospective study; recurrence risk; recurrent disease; risk factor; systematic review; thyrotropin blood level; blood; Graves disease; recurrent disease; treatment withdrawal; Antithyroid Agents; Graves Disease; Humans; Recurrence; Thyrotropin; Withholding Treatment |
Public Library of Science |
19326203 |
|
33513181 |
Article |
Q1 |
990 |
4434 |
|
|
889 |
Irdam G.A., Sutojo B., Raharja P.A.R. |
57194729795;57218247988;57201013616; |
Risk Factors of Ureteral Stenosis in Kidney Transplant Recipients: A Retrospective Study in National Referral Hospital in Indonesia |
2021 |
Advances in Urology |
2021 |
|
2410951 |
|
|
|
1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100218047&doi=10.1155%2f2021%2f2410951&partnerID=40&md5=8c80f4380c17c32aba39dc8572cc7807 |
Department of Urology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia |
Irdam, G.A., Department of Urology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia; Sutojo, B., Department of Urology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia; Raharja, P.A.R., Department of Urology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia |
Ureteral stenosis is one of the most common urological complications following kidney transplantations. It is occurred in 2-10% of patients and poses a significant problem to the patients as it may lead to permanent damage to renal damage. Identification of risk factors is important to prevent the incidence of ureteral stenosis. Thus, we aim to determine the risk factors of ureteral stenosis in the Indonesian population. This is a retrospective analysis of 487 kidney transplant patients performed in Cipto Mangunkusumo Hospital between 2014 and 2018. We collected and compared donor and recipient demography data in recipients who developed ureteral stenosis and recipients who did not develop ureteral stenosis. Ureteral stenosis was defined as the presence of hydronephrosis from ultrasound and increased number of serum creatinine. The overall incidence of ureteral stenosis post-kidney transplantation in our center is 6.6% (32 from 487 patients) from January 2014 until June 2018. We found that older donor and recipient age more frequent in developing ureteral stenosis post-kidney transplantation (p < 0.001). We also found that donors with number of arteries more than 2 (p < 0.001) and prolonged warm ischemic time (p < 0.05) are more frequently to develop ureteral stenosis post-kidney transplantation. There is no association between type II diabetes mellitus and hypertension with ureteral stenosis in this study. Donor age, recipient age, donor number of arteries more than 2, and prolonged warm ischemia time are associated with ureteral stenosis after kidney transplantation. © 2021 Gampo A. Irdam et al. |
|
creatinine; adolescent; adult; age; aged; allograft; Article; child; creatinine blood level; disease association; female; graft recipient; human; hydronephrosis; hypertension; Indonesia; ischemia time; kidney donor; kidney graft; kidney transplantation; major clinical study; male; medical history; neurogenic bladder; non insulin dependent diabetes mellitus; postoperative period; retrospective study; risk factor; ureter obstruction; warm ischemia time |
Hindawi Limited |
16876369 |
|
|
Article |
Q1 |
1180 |
3392 |
|
|
897 |
Oshima T., Siah K.T.H., Kim Y.S., Patcharatrakul T., Chen C.-L., Mahadeva S., Park H., Chen M.-H., Lu C.-L., Hou X., Quach D.T., Syam A.F., Rahman M.M., Xiao Y., Jinsong L., Chua A.S.B., Miwa H. |
7401663152;35757936600;57196171210;8549899200;23495616400;6602694336;56255219600;57216452428;7404805612;57210061408;37099075800;8443384400;57216556340;23500436000;57221693058;7004518894;56921458500; |
Knowledge, attitude, and practice survey of gastroparesis in asia by asian neurogastroenterology and motility association |
2021 |
Journal of Neurogastroenterology and Motility |
27 |
1 |
|
46 |
54 |
|
5 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099728456&doi=10.5056%2fJNM20117&partnerID=40&md5=49d79381fdad1a0dca816161fd54b8e0 |
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Division of Gastroenterology and Hepatology, Department of Medicine, National University Hospital, Singapore, Singapore; Digestive Disease Research Institute, School of Medicine, Wonkwang University, Iksan, Jeollabuk-do, South Korea; Center of Excellence in Neurogastroenterology and Motility, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; Division of Gastroenterology, Department of Medicine, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand; Department of Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Tzu Chi University, Hualien, Taiwan; Institute of Medical Sciences, College of Medicine, Tzu Chi University, Hualien, Taiwan; Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia; Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University, Seoul, South Korea; Department of Gastroenterology and Hepatology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; Endoscopy Center for Diagnosis and Treatment, Taipei Veterans General Hospital, Taipei, Taiwan; Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Department of Internal Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh, Viet Nam; Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta Pusat, Indonesia; Department of Gastroenterology, Sheikh Russel National Gastroliver Institute and Hospital, Dhaka, Bangladesh; Gastro Center Ipoh, Ipoh, Malaysia |
Oshima, T., Division of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan; Siah, K.T.H., Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, Division of Gastroenterology and Hepatology, Department of Medicine, National University Hospital, Singapore, Singapore; Kim, Y.S., Digestive Disease Research Institute, School of Medicine, Wonkwang University, Iksan, Jeollabuk-do, South Korea; Patcharatrakul, T., Center of Excellence in Neurogastroenterology and Motility, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand, Division of Gastroenterology, Department of Medicine, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand; Chen, C.-L., Department of Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Tzu Chi University, Hualien, Taiwan, Institute of Medical Sciences, College of Medicine, Tzu Chi University, Hualien, Taiwan; Mahadeva, S., Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia; Park, H., Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University, Seoul, South Korea; Chen, M.-H., Department of Gastroenterology and Hepatology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; Lu, C.-L., Endoscopy Center for Diagnosis and Treatment, Taipei Veterans General Hospital, Taipei, Taiwan; Hou, X., Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Quach, D.T., Department of Internal Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh, Viet Nam; Syam, A.F., Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta Pusat, Indonesia; Rahman, M.M., Department of Gastroenterology, Sheikh Russel National Gastroliver Institute and Hospital, Dhaka, Bangladesh; Xiao, Y., Department of Gastroenterology and Hepatology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; Jinsong, L., Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Chua, A.S.B., Gastro Center Ipoh, Ipoh, Malaysia; Miwa, H., Division of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan |
Background/Aims Gastroparesis is identified as a subject that is understudied in Asia. The scientific committee of the Asian Neurogastroenterology and Motility Association performed a Knowledge, Attitude, and Practices survey on gastroparesis among doctors in Asia. Methods The questionnaire was created and developed through a literature review of current gastroparesis works of literature by the scientific committee of Asian Neurogastroenterology and Motility Association. Results A total of 490 doctors from across Asia (including Bangladesh, China, Hong Kong, Indonesia, Japan, Malaysia, Myanmar, the Philippines, Singapore, South Korea, Taiwan, Thailand, and Vietnam) participated in the survey. Gastroparesis is a significant gastrointestinal condition. However, a substantial proportion of respondents was unable to give the correct definition and accurate diagnostic test. The main reason for lack of interest in diagnosing gastroparesis was "the lack of reliable diagnostic tests"(46.8%) or "a lack of effective treatment"(41.5%). Only 41.7% of respondents had access to gastric emptying scintigraphy. Most doctors had never diagnosed gastroparesis at all (25.2%) or diagnosed fewer than 5 patients a year (52.1%). Conclusions Gastroparesis can be challenging to diagnose due to the lack of instrument, standardized method, and paucity of research data on normative value, risk factors, and treatment studies in Asian patients. Future strategies should concentrate on how to disseminate the latest knowledge of gastroparesis in Asia. In particular, there is an urgent need to estimate the magnitude of the problems in high risk and idiopathic patients as well as a standardized diagnostic procedure in Asia. © 2021 The Korean Society of Neurogastroenterology and Motility. |
Asia; Dyspepsia; Gastroparesis; Health care surveys; Health education |
Article; Asia; Bangladesh; China; demography; diagnostic test; female; Hong Kong; human; Indonesia; Japan; knowledge; Malaysia; male; medical society; Myanmar; Philippines; physician attitude; questionnaire; scintigraphy; Singapore; South Korea; stomach emptying; stomach paresis; Taiwan; test meal; Thailand; Viet Nam |
Korean Society of Neurogastroenterology and Motility |
20930879 |
|
|
Article |
Q1 |
1345 |
2715 |
|
|
901 |
Kadosh K.C., Muhardi L., Parikh P., Basso M., Mohamed H.J.J., Prawitasari T., Samuel F., Ma G., Geurts J.M.W. |
12243251700;57216729101;35269493300;57221482131;41861368100;57190686255;14421774000;57199673360;57197926057; |
Nutritional support of neurodevelopment and cognitive function in infants and young children—an update and novel insights |
2021 |
Nutrients |
13 |
1 |
199 |
1 |
26 |
|
4 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099415887&doi=10.3390%2fnu13010199&partnerID=40&md5=9754b1ffd94e454fc9ae27ba058537af |
School of Psychology, University of Surrey, Guildford, GU2 7XH, United Kingdom; FrieslandCampina AMEA, Singapore, 039190, Singapore; Department of General Psychology, University of Padova, Padova, 35131, Italy; Nutrition and Dietetics Programme, School of Health Sciences, Universiti Sains Malaysia, Kubang Kerian, 16150, Malaysia; Nutrition and Metabolic Diseases Working Group, Indonesian Pediatric Society, Jakarta, 10310, Indonesia; Department of Pediatrics, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusomo National Referral Hospital Jakarta, Jakarta, 10430, Indonesia; Department of Human Nutrition, University of Ibadan, Ibadan, 200284, Nigeria; Department of Nutrition and Food Hygiene, School of Public Health, Peking University, 38 Xue Yuan Road, Haidian District, Beijing, 10019, China; Laboratory of Toxicological Research and Risk assessment for Food Safety, Peking University, 38 Xue Yuan Road, Haidian District, Beijing, 100191, China; FrieslandCampina, Amersfoort, 3818 LE, Netherlands |
Kadosh, K.C., School of Psychology, University of Surrey, Guildford, GU2 7XH, United Kingdom; Muhardi, L., FrieslandCampina AMEA, Singapore, 039190, Singapore; Parikh, P., FrieslandCampina AMEA, Singapore, 039190, Singapore; Basso, M., School of Psychology, University of Surrey, Guildford, GU2 7XH, United Kingdom, Department of General Psychology, University of Padova, Padova, 35131, Italy; Mohamed, H.J.J., Nutrition and Dietetics Programme, School of Health Sciences, Universiti Sains Malaysia, Kubang Kerian, 16150, Malaysia; Prawitasari, T., Nutrition and Metabolic Diseases Working Group, Indonesian Pediatric Society, Jakarta, 10310, Indonesia, Department of Pediatrics, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusomo National Referral Hospital Jakarta, Jakarta, 10430, Indonesia; Samuel, F., Department of Human Nutrition, University of Ibadan, Ibadan, 200284, Nigeria; Ma, G., Department of Nutrition and Food Hygiene, School of Public Health, Peking University, 38 Xue Yuan Road, Haidian District, Beijing, 10019, China, Laboratory of Toxicological Research and Risk assessment for Food Safety, Peking University, 38 Xue Yuan Road, Haidian District, Beijing, 100191, China; Geurts, J.M.W., FrieslandCampina, Amersfoort, 3818 LE, Netherlands |
Proper nutrition is crucial for normal brain and neurocognitive development. Failure to optimize neurodevelopment early in life can have profound long-term implications for both mental health and quality of life. Although the first 1000 days of life represent the most critical period of neurodevelopment, the central and peripheral nervous systems continue to develop and change throughout life. All this time, development and functioning depend on many factors, including adequate nutrition. In this review, we outline the role of nutrients in cognitive, emotional, and neural development in infants and young children with special attention to the emerging roles of polar lipids and high quality (available) protein. Furthermore, we discuss the dynamic nature of the gut-brain axis and the importance of microbial diversity in relation to a variety of outcomes, including brain maturation/function and behavior are discussed. Finally, the promising therapeutic potential of psychobiotics to modify gut microbial ecology in order to improve mental well-being is presented. Here, we show that the individual contribution of nutrients, their interaction with other micro-and macronutrients and the way in which they are organized in the food matrix are of crucial importance for normal neurocognitive development. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
Brain; Childhood; Gut-brain axis; Kynurenine; Minerals; Neurodevelopment; Polar lipids; Polyunsaturated fatty acids; Prebiotics; Probiotics; Protein quality; Tryptophan; Tyrosine; Vitamins |
amino acid; branched chain amino acid; cyanocobalamin; iodine; iron; lipid; long chain fatty acid; mammalian target of rapamycin complex 1; phenylalanine; polar lipid; polyunsaturated fatty acid; prebiotic agent; probiotic agent; retinol; trace element; tryptophan; tyrosine; unclassified drug; vitamin D; zinc; fatty acid; kynurenine; mineral; brain development; child; cognition; emotion; human; infant; infant nutrition; intestine flora; macronutrient; nerve cell differentiation; nonhuman; nutritional support; protein intake; protein quality; Review; brain; cognitive aging; food; growth, development and aging; preschool child; quality of life; Brain; Child, Preschool; Cognition; Cognitive Aging; Emotions; Fatty Acids; Food; Gastrointestinal Microbiome; Humans; Infant; Kynurenine; Minerals; |
MDPI AG |
20726643 |
|
33435231 |
Review |
Q1 |
1418 |
2497 |
|
|
908 |
Lazarus G., Audrey J., Wangsaputra V.K., Tamara A., Tahapary D.L. |
57214599425;57217634074;57215576000;57205305387;55944492500; |
High admission blood glucose independently predicts poor prognosis in COVID-19 patients: A systematic review and dose-response meta-analysis |
2021 |
Diabetes Research and Clinical Practice |
171 |
|
108561 |
|
|
|
20 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85098602441&doi=10.1016%2fj.diabres.2020.108561&partnerID=40&md5=16a5cb07b3f5de39c14a9eb1370dcd17 |
Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Metabolic, Cardiovascular and Aging Cluster, The Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Division of Endocrinology and Metabolism, Department of Internal Medicine, Dr. Cipto Mangunkusumo General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Lazarus, G., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Audrey, J., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Wangsaputra, V.K., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Tamara, A., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Metabolic, Cardiovascular and Aging Cluster, The Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Tahapary, D.L., Metabolic, Cardiovascular and Aging Cluster, The Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Division of Endocrinology and Metabolism, Department of Internal Medicine, Dr. Cipto Mangunkusumo General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Aims: To investigate the prognostic value of admission blood glucose (BG) in predicting COVID-19 outcomes, including poor composite outcomes (mortality/severity), mortality, and severity. Methods: Eligible studies evaluating the association between admission fasting BG (FBG) and random BG (RBG) levels with COVID-19 outcomes were included and assessed for risk of bias with the Quality in Prognosis Studies tool. Random-effects dose-response meta-analysis was conducted to investigate potential linear or non-linear exposure-response gradient. Results: The search yielded 35 studies involving a total of 14,502 patients. We discovered independent association between admission FBG and poor COVID-19 prognosis. Furthermore, we demonstrated non-linear relationship between admission FBG and severity (Pnon-linearity < 0.001), where each 1 mmol/L increase augmented the risk of severity by 33% (risk ratio 1.33 [95% CI: 1.26–1.40]). Albeit exhibiting similar trends, study scarcity limited the evidence strength on the independent prognostic value of admission RBG. GRADE assessment yielded high-quality evidence for the association between admission FBG and COVID-19 severity, and moderate-quality evidence for its association with mortality and poor outcomes. Conclusion: High admission FBG level independently predicted poor COVID-19 prognosis. Further research to confirm the prognostic value of admission RBG and to ascertain the estimated dose-response risk between admission FBG and COVID-19 severity are required. © 2020 Elsevier B.V. |
Blood glucose; COVID-19; Fasting; Patient admission; Prognosis |
glucose; Article; coronavirus disease 2019; diabetes mellitus; disease association; disease severity; evidence based medicine; glucose blood level; high risk population; hospital admission; human; hyperglycemia; intensive care unit; meta analysis; mortality; outcome assessment; prognosis; risk assessment; systematic review; complication; diabetes mellitus; hyperglycemia; isolation and purification; metabolism; mortality; pathophysiology; prognosis; risk factor; survival rate; virology; Blood Glucose; COVID-19; Diabetes Mellitus; Humans; Hyperglycemia; Prognosis; Risk Factors; SARS-CoV-2; Survival Rate |
Elsevier Ireland Ltd |
01688227 |
|
33310127 |
Article |
Q1 |
1605 |
2008 |
|
|
909 |
Sugianto J.A., Hadipranata T., Lazarus G., Amrullah A.H. |
57221192052;57221199976;57214599425;57221196528; |
Proximal fibular osteotomy for the management of medial compartment knee osteoarthritis: A systematic review and meta-analysis |
2021 |
Knee |
28 |
|
|
169 |
185 |
|
3 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85098481652&doi=10.1016%2fj.knee.2020.11.020&partnerID=40&md5=3036d47b70bc39dabc84ff7ada033e00 |
Ngimbang General Hospital, LamonganEast Java, Indonesia; Faculty of Medicine, Universitas IndonesiaJakarta, Indonesia; Orthopaedic and Traumatology Surgeon, Ngimbang General HospitalEast Java, Indonesia |
Sugianto, J.A., Ngimbang General Hospital, LamonganEast Java, Indonesia; Hadipranata, T., Ngimbang General Hospital, LamonganEast Java, Indonesia; Lazarus, G., Faculty of Medicine, Universitas IndonesiaJakarta, Indonesia; Amrullah, A.H., Orthopaedic and Traumatology Surgeon, Ngimbang General HospitalEast Java, Indonesia |
Background: The promising prospects of proximal fibular osteotomy (PFO) as an alternative treatment of knee osteoarthritis (KOA), which has gained popularity in recent years, has yet to be systematically evaluated. Hence, this meta-analysis aims to critically assess the clinical and radiological outcome of PFO in the management of medial compartment KOA. Methods: Literature searches through PubMed, Scopus, CENTRAL, CINAHL, Google Scholar, and ProQuest databases were conducted, searching for eligible studies published from inception up to April 2020. Risk of bias assessments of randomized trials were performed via Cochrane RoB 2, while those of non-randomized studies with ROBINS-I tool. Random-effects model was utilized to estimate effect sizes. Results: A total of 907 patients and 1012 knees were included in this meta-analysis. PFO successfully ameliorated patients’ knee function (Hedges’ g 1.90; 95% confidence interval (CI) 1.62–2.18; I2 = 67%) and pain (visual analog scale: mean difference (MD) −4.13; 95% CI: −5.29 to −2.97), and also resulted in minimal complication rates, with peroneal nerve paresthesia being the most prevalent adverse event (5.93%; 95% CI: 2.15–11.25%), followed by peroneal nerve palsy (2.25%; 95% CI: 0.14–6.14%), fracture (0.56%; 95% CI: 0–1.74%), and recurrent deformity (0.54%; 95% CI: 0–1.74%). Furthermore, PFO was also associated with improved medial/lateral joint space ratio (MD 0.17; 95% CI: 0.15–0.19). Conclusion: PFO yielded promising prospects in the management of medial compartment KOA, as shown by substantial improvements in clinical and radiological outcomes. However, considering the low quality of evidence, further studies with more diverse populations and higher quality of body evidence are required to confirm these findings. © 2020 Elsevier B.V. |
High fibular osteotomy; Knee osteoarthritis; Osteotomy; Proximal fibular osteotomy; Upper partial fibulectomy |
anthropometric parameters; bone malformation; fracture; human; joint cavity; knee function; knee osteoarthritis; knee pain; lateral joint space; medial joint space; meta analysis; osteotomy; peroneus nerve paralysis; postoperative complication; prevalence; priority journal; proximal fibular osteotomy; radiological procedures; randomized controlled trial (topic); recurrent disease; Review; systematic review; treatment outcome; visual analog scale; adverse event; fibula; knee osteoarthritis; osteotomy; postoperative complication; procedures; Fibula; Humans; Osteoarthritis, Knee; Osteotomy; Postoperative Complications; Visual Analog Scale |
Elsevier B.V. |
09680160 |
|
33387808 |
Review |
Q1 |
1012 |
4317 |
|
|