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564 |
Ahlam Syakirah W.N., Shafie W.M., Mansyur M., Nor N.Md. |
57223025872;57223022488;37085506800;57209597416; |
A Systematic Review on Precision Nutrition for Prevention and Management of Obesity during COVID-19 |
2021 |
Pakistan Journal of Medical and Health Sciences |
15 |
2 |
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223 |
230 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85104525366&partnerID=40&md5=abe25d87c69c1fb5f8ba0283e4701cc2 |
Centre of Nutrition and Dietetics Studies, Faculty of Health Sciences, Universiti Teknologi MARA, Malaysia; Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Indonesia; Maternal, Infant & Young Child Nutrition (MiChild) Research Group, Faculty of Health Sciences, Universiti Teknologi MARA, Malaysia |
Ahlam Syakirah, W.N.; Shafie, W.M., Centre of Nutrition and Dietetics Studies, Faculty of Health Sciences, Universiti Teknologi MARA, Malaysia; Mansyur, M., Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Indonesia; Nor, N.Md., Centre of Nutrition and Dietetics Studies, Faculty of Health Sciences, Universiti Teknologi MARA, Malaysia, Maternal, Infant & Young Child Nutrition (MiChild) Research Group, Faculty of Health Sciences, Universiti Teknologi MARA, Malaysia |
The COVID-19 pandemic is now catching the country by surprise. The disease has had a huge influence worldwide, and the nation has been put in lockdown by this health crisis. The psychological health, physical health and economic condition of individuals are adversely impacted by quarantine and lockdown. As mobility is reduced, there will be a dramatic shift in the population's lifestyle, where the people's physical activity level will decrease. Low levels of physical exercise can lead to a large number of obesity cases. Therefore, steps for obesity prevention and management need to be taken. One approach is to administer nutrition with accuracy through precision nutrition. Therefore, this research aims to review articles on precision nutrition for the treatment and control of obesity towards a restricted movement order during the COVID-19 health crisis. The literature search was conducted from May 2020 until January 2021 using Scopus and Science Direct as the main databases. The articles included follow the inclusion criteria published in English language, including nutrition intervention for prevention and management of obesity, focus on health crisis, and no restriction of time and study design. Various studies show that precision nutrition has a potential benefit in preventing or controlling obesity prevalence due to restricted movement order or quarantine upon health crisis. © 2021 Lahore Medical And Dental College. All rights reserved. |
COVID-19; Lockdown; Obesity; Precision nutrition; Quarantine |
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Lahore Medical And Dental College |
19967195 |
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Review |
Q4 |
114 |
27922 |
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640 |
Yulia D.E., Pambudy I.M., Amanda L. |
57225947931;57327482000;57225929959; |
Review of Corticosteroid Use in Pediatric Cataract Surgery |
2021 |
Open Ophthalmology Journal |
15 |
1 |
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251 |
257 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85122381840&doi=10.2174%2f1874364102115010251&partnerID=40&md5=443070a1878e6bcf97e1132e3d5f8357 |
Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Yulia, D.E., Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Pambudy, I.M., Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Amanda, L., Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Introduction: Following pediatric cataract surgery, an intense inflammatory response is related to various complications, including posterior capsule opacification (PCO), which is a visually threatening incidence that can lead to visual axis opacification (VAO). Although corticosteroids are essentially effective in reducing inflammation, potential ocular side effects are a remaining concern. Objective: This study aimed to review the efficacy and safety of corticosteroid drugs and their administration routes in pediatric patients who underwent cataract surgery Methods: A literature search was conducted from four electronic databases using keywords selected a priori. Identified articles were sorted according to the type of corticosteroid used, route of administration, and outcome measures, including inflammatory response and ocular side effects. Results: Five studies were included with one case series, one retrospective case-control, and three clinical trials. The total number of subjects was 311 patients, with an age range of six weeks to 15 years old. Four studies analyzed the use of triamcinolone acetonide intracamerally, which was superior to topical steroids. Most of the studies reported a decrease in inflammatory parameters. The outcome of PCO and VAO varied between studies. Nearly all the studies observed elevated intraocular pressure (IOP) as an ocular side effect. Conclusion: Various corticosteroids and different delivery routes can be used to ameliorate inflammation in pediatric cataract surgery. However, there is promising evidence suggesting intracameral steroids as substantially beneficial in reducing inflammatory parameters. Due to the limited number of studies reviewed, no firm conclusion regarding the superior steroid preparation or route of administration can be inferred. This review highlights the need for further studies. © 2021 Yulia et al. |
Corticosteroid; Drug administration; Inflammation; Ocular side effect; Pediatric cataract surgery; Posterior capsular opacification |
corticosteroid; cataract; cataract extraction; drug administration route; drug safety; human; inflammation; intraocular pressure; outcome assessment; pediatric patient; pediatric surgery; Review; side effect; topical drug administration |
Bentham Science Publishers |
18743641 |
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Review |
Q2 |
670 |
7468 |
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648 |
Sungkar A. |
55110453800; |
Preterm birth in low-resource setting |
2021 |
Donald School Journal of Ultrasound in Obstetrics and Gynecology |
15 |
2 |
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175 |
178 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85121540929&doi=10.5005%2fjp-journals-10009-1695&partnerID=40&md5=6bdfb4b0abc69737097e5332647cdcc6 |
Fetomaternal Division, Department of Obstetrics and Gynecology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Cipto Mangunkusumo National Hospital, Jakarta, Indonesia |
Sungkar, A., Fetomaternal Division, Department of Obstetrics and Gynecology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia, Cipto Mangunkusumo National Hospital, Jakarta, Indonesia |
Preterm labor (PTL) is a global problem which is a complex disease with a high rate of morbidity and mortality, also has long-term consequences for the baby and the family. The well-known morbidities related to PTL are respiratory distress syndrome, necrotizing enterocolitis, intraventricular hemorrhage, retinopathy of prematurity, and anemia of prematurity. In a developing country, the management of PTL is limited by poor health systems, low education level of the mother, poor financial support, lack of facility and trained health personnel, and demographic barriers. This limitation leads to high morbidity and mortality of preterm birth, especially in developing countries. It is important to reduce the rate of preterm birth by preventing the event. Several risk factors have been identified and are avoidable and preventable, such as smoking, bacterial infection, poor nutritional status, and malnourished mothers. Strategies to prevent PTL have been proposed in primary, secondary, and tertiary interventions to reduce the morbidity and mortality of preterm birth. © Jaypee Brothers Medical Publishers. 2021. |
Management; Morbidity and mortality; Preterm labor; Risk factor |
fibronectin; folic acid; homocysteine; iron; trace element; zinc; allergy; body mass; cigarette smoking; early diagnosis; endocrine disease; gestational weight gain; graft rejection; human; hyperhomocysteinemia; hypertension; infertility therapy; intrauterine growth retardation; intrauterine infection; ischemia; macronutrient; morbidity; mortality; multiple pregnancy; non communicable disease; nutritional deficiency; preeclampsia; pregnancy diabetes mellitus; premature labor; prepregnancy care; Review; risk factor; transvaginal echography; uterine cervix carcinoma in situ; uterine cervix incompetence; vascular disease |
Jaypee Brothers Medical Publishers (P) Ltd |
0973614X |
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Review |
Q4 |
162 |
22036 |
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673 |
Kaaffah S., Soewondo P., Riyadina W., Renaldi F.S., Sauriasari R. |
57331465300;23475336100;57208470391;57331465400;16246507200; |
Adherence to treatment and glycemic control in patients with type 2 diabetes mellitus: A 4-year follow-up ptm bogor cohort study, indonesia |
2021 |
Patient Preference and Adherence |
15 |
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2467 |
2477 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118951660&doi=10.2147%2fPPA.S318790&partnerID=40&md5=079f3b92c2c91638e7785757da719eff |
Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia; Division of Endocrinology, Department of Internal Medicine, Dr.Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Metabolic, Cardiovascular and Aging Cluster, The Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; National Institute of Health Research and Development, Ministry of Health Republic of Indonesia, Jakarta, Indonesia |
Kaaffah, S., Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia; Soewondo, P., Division of Endocrinology, Department of Internal Medicine, Dr.Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Metabolic, Cardiovascular and Aging Cluster, The Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Riyadina, W., National Institute of Health Research and Development, Ministry of Health Republic of Indonesia, Jakarta, Indonesia; Renaldi, F.S., Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia; Sauriasari, R., Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia |
Purpose: Large-scale evaluation of the treatment adherence in patients with type 2 diabetes mellitus (DM) in Indonesian is limited. We aim to evaluate the treatment adherence of Indonesian type 2 DM patients using national “big data” and investigate its association with glycemic parameters. Patients and Methods: We analyzed baseline and fourth-year data sets from 2011 to 2018 obtained from the Indonesian Ministry of Health Cohort Study of Non-Communicable Disease Risk Factors in Bogor, West Java (the PTM Bogor Cohort Study). This was a retrospective cohort study in which the sample was divided into two groups. One group adhered to treatment from primary health centers and followed the prescribed medicine/ treatment regimen (treated group), while the other did not follow the treatment (untreated group). We evaluated changes in fasting blood glucose (FBG) and post-prandial blood glucose (PPBG) by controlling for other variables. Results: From 5690 subjects, 593 were type 2 DM diagnosed and 342 were eligible at the baseline. At 4-year observation, 212 eligible patients remained, consisting of 62 subjects who adhered to treatment, and more than double that number who were untreated (150 subjects). More significant decreases in FBG and PPBG were found in the treated group (FBG 80.6%, PPBG 90.3%) than in the untreated group (FBG 42.0%, PPBG 67.3%). The results of the multivariate analysis showed that after 4 years observation, treated patients have reduced FBG 3.304 times more and PPBG 3.064 times more than untreated patients, with control factors such as decrease in LDL levels and use of oral drugs. Conclusion: There were less than half as many treated patients as untreated patients involved in the PTM Bogor Study Group. At the fourth-year follow-up, treated patients experienced three times more significant decreases in FBG and PPBG than those who were untreated, even after being controlled by several confounding factors. Given the importance of these findings, it is suggested that immediate strategic action be taken to improve Indonesian patients’ adherence to treatment. © 2021 Kaaffah et al. |
Cohort; Diabetes mellitus; Fasting blood glucose; Post-prandial blood glucose; Treatment adherence |
glibenclamide; glimepiride; glucose; insulin; low density lipoprotein; metformin; sulfonylurea; adult; Article; big data; cohort analysis; controlled study; fasting; female; follow up; glucose blood level; glycemic control; human; Indonesia; major clinical study; male; medication compliance; middle aged; non insulin dependent diabetes mellitus; patient compliance; prescription; primary health care; retrospective study |
Dove Medical Press Ltd |
1177889X |
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Article |
Q1 |
885 |
5263 |
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763 |
Gunardi W.D., Timotius K.H., Natasha A., Evriarti P.R. |
57222314683;24299781600;57211428938;57226004232; |
Biofilm targeting strategy in the eradication of burkholderia infections: A mini-review |
2021 |
Open Microbiology Journal |
15 |
1 |
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51 |
57 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85110074931&doi=10.2174%2f1874285802115010051&partnerID=40&md5=70632c812ea82598129daf4afdd465df |
Department of Microbiology, Faculty of Medicine, Krida Wacana Christian University (UKRIDA), Jakarta, Indonesia; Program in Biomedical Science, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Microbiolgy, Health Labortory of Makassar (BBLK Makassar), Makassar, Indonesia |
Gunardi, W.D., Department of Microbiology, Faculty of Medicine, Krida Wacana Christian University (UKRIDA), Jakarta, Indonesia; Timotius, K.H., Department of Microbiology, Faculty of Medicine, Krida Wacana Christian University (UKRIDA), Jakarta, Indonesia; Natasha, A., Program in Biomedical Science, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Evriarti, P.R., Program in Biomedical Science, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Microbiolgy, Health Labortory of Makassar (BBLK Makassar), Makassar, Indonesia |
Burkholderia are intracellular pathogenic bacteria which can produce biofilm. This biofilm protects the intracellular pathogenic bacteria from antibiotic treatment and the immunological system of the host. Therefore, this review aims to describe the capacity of Burkholderia to form a biofilm, the regulation of its biofilm formation, the efficacy of antibiotics to eradicate biofilm, and the novel therapy which targets its biofilm. Burkholderia's biofilm is characterized by its lipopolysaccharides, exopolysaccharides (EPSs), biofilm-associated proteins, and eDNA. Its regulation is made by quorum sensing, c-di-AMP, sRNA, and two component systems. Many antibiotics have been used as sole or mixture agents; however, they are not always effective in eradicating the biofilm-forming Burkholderia. Inhibitors of quorum sensing and other non-conventional antibiotic approaches are promising to discover effective treatment of Burkholderia infections. © 2021, Bentham Science Publishers. All rights reserved. |
Antibiotic; Biofilm; Burkholderia; Exopolysaccharide; Lipid A; Quorum sensing |
acetazolamide; amoxicillin; antibiotic agent; cefepime; ceftazidime; colistin; echinocandin; exopolysaccharide; gentamicin; imipenem; indisulam; lipopolysaccharide; macrolide; meropenem; piperacillin plus tazobactam; polymyxin B; RANTES; saccharin; sulpiride; tobramycin; topiramate; transcriptome; vancomycin; virulence factor; Acinetobacter baumannii; antibiofilm activity; antibiotic resistance; antibiotic sensitivity; antibiotic therapy; apoptosis; Article; autolysis; bacteremia; bacterial arthritis; bacterial colonization; bacterial gene; bacterial growth; bacterial virulence; Betaproteobacteria; biofilm; Burkholderia cenocepacia; Burkholderia infection; Burkholderia pseudomallei; cell aggregation; DNA damage; Enterococcus faecalis; extracellular matrix; gene; gene expression; Helicobact |
Bentham Science Publishers |
18742858 |
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Article |
Q3 |
502 |
10043 |
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768 |
Midoen Y.H., Suryandari D.A., Yunaini L., Susworo R., Auerkari E.I., Freisleben H.-J. |
57197805109;6505763338;57192911515;8438653400;10139113000;7003437337; |
Epstein-Barr virus nuclear antigen-1 is useful as therapeutic efficacy marker in serum but not in saliva of nasopharyngeal cancer patients who underwent radiotherapy |
2021 |
ecancermedicalscience |
15 |
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1254 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85109546581&doi=10.3332%2fECANCER.2021.1254&partnerID=40&md5=debd5ca3a84a84eabb9d16f1bf92fc2d |
Department of Medical Biology, Faculty of Medicine, Universitas Indonesia, Jalan Salemba Raya 6, Jakarta, 10430, Indonesia; Department of Radiotherapy, Faculty of Medicine, Universitas Indonesia and Cipto Mangunkusumo Hospital, Jalan Pangeran Diponegoro 71, Jakarta, 10430, Indonesia; Department of Oral Biology, Faculty of Dentistry, Universitas Indonesia, Jalan Salemba Raya 4, Jakarta, 10430, Indonesia; Medical Research Unit, Faculty of Medicine, Universitas Indonesia, Jalan Salemba Raya 4, Jakarta, 10430, Indonesia |
Midoen, Y.H., Department of Medical Biology, Faculty of Medicine, Universitas Indonesia, Jalan Salemba Raya 6, Jakarta, 10430, Indonesia; Suryandari, D.A., Department of Medical Biology, Faculty of Medicine, Universitas Indonesia, Jalan Salemba Raya 6, Jakarta, 10430, Indonesia; Yunaini, L., Department of Medical Biology, Faculty of Medicine, Universitas Indonesia, Jalan Salemba Raya 6, Jakarta, 10430, Indonesia; Susworo, R., Department of Radiotherapy, Faculty of Medicine, Universitas Indonesia and Cipto Mangunkusumo Hospital, Jalan Pangeran Diponegoro 71, Jakarta, 10430, Indonesia; Auerkari, E.I., Department of Oral Biology, Faculty of Dentistry, Universitas Indonesia, Jalan Salemba Raya 4, Jakarta, 10430, Indonesia; Freisleben, H.-J., Medical Research Unit, Faculty of Medicine, Universitas Indonesia, Jalan Salemba Raya 4, Jakarta, 10430, Indonesia |
Introduction: Nasopharyngeal carcinoma (NPC) is a multifactorial disease with genetic, viral, environmental and lifestyle-related risk factors. Epstein-Barr virus (EBV) can promote the oncogenic transformation of an infected cell into malignant. EBV encodes many stimulating products including Epstein-Barr virus nuclear antigen-1 (EBNA-1) which plays a key role in the regulation of gene expression and replication of the genome in the latent period of infection. EBNA-1 in serum and tumour tissue of NPC patients correlates with NPC prognosis. Moreover, the presence of EBV DNA in serum samples from NPC patients' blood circulation can be used as an early marker in the diagnosis of NPC. Objective: The objective of this study was to find effective methods for monitoring the progress of NPC patients undergoing radiotherapy and therapeutic efficacy by observing the changes in EBV DNA in serum and saliva. Methodology: The pre-experimental design compared blood and saliva taken from a pretest and post-test group of NPC patients before and after radiation therapy. The concentration of EBV DNA was measured in the serum and saliva after amplification using quantitative polymerase chain reaction (qPCR) with compatible primers for the EBNA-1 gene. The data were statistically analysed by paired T-test. Results: Highly significant (p = 0.0001) increase in cycle threshold qPCR and decrease in the mean concentration of EBV DNA (p = 0.0001) were observed in serum samples, but no significant changes were observed in saliva. Conclusions: The results suggest that EBV DNA in serum can be used as the gold standard and a marker for monitoring the response to radiation therapy in NPC patients, whereas the examination of EBV DNA from saliva samples is not accurate and thus, not appropriate. © 2021 ecancer Global Foundation. All rights reserved. |
CT; EBNA-1; EBV DNA; NPC; QPCR |
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ecancer Global Foundation |
17546605 |
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Article |
Q3 |
708 |
7022 |
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772 |
Maryam R.S., Sahar J., Hastono S.P., Harimurti K. |
57209730009;6508226729;57211434645;23473513200; |
Common symptoms of alzheimer’s dementia that are easily recognizable by families [Sintomas comuns da demência de alzheimer facilmente reconhecíveis pelas famílias] |
2021 |
Dementia e Neuropsychologia |
15 |
2 |
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186 |
191 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85109080999&doi=10.1590%2f1980-57642021dn15-020005&partnerID=40&md5=7d8636011b9ebdb60c6dd608e999cc16 |
Faculty of Nursing, Universitas Indonesia, Jawa Barat, Indonesia; Faculty of Medicine, Universitas Indonesia, Jawa Barat, Indonesia; Faculty of Public Health, Universitas Indonesia, Jawa Barat, Indonesia |
Maryam, R.S., Faculty of Nursing, Universitas Indonesia, Jawa Barat, Indonesia; Sahar, J., Faculty of Nursing, Universitas Indonesia, Jawa Barat, Indonesia; Hastono, S.P., Faculty of Medicine, Universitas Indonesia, Jawa Barat, Indonesia; Harimurti, K., Faculty of Public Health, Universitas Indonesia, Jawa Barat, Indonesia |
The increase in dementia incidence among the elderly is directly related to aging, which is associated with changes in bodily functions and other health-related risk factors. Alzheimer’s dementia is the most prevalent form of dementia, and individuals in the late stages are predominantly dependent on other family members. Therefore, it is important for families, as the closest support group, to recognize common symptoms early. Objective: To provide a family-friendly guide to the ten common symptoms of Alzheimer’s dementia. Methods: This is a descriptive survey-based research that included 354 families comprising elderly people (≥60 years) residing in Jakarta. The instrument aimed at identifying ten common Alzheimer’s dementia symptoms in Indonesia. Descriptive statistical analysis based on frequency tables was used. Results: The participant’s major characteristics were age ≥66 years (52.3%), female sex (70.3%) and primary school education (87.3%). The predominant symptoms experienced by 42.4% of the elderly included forgetting recent events and asking questions and narrating a particular detail repeatedly. The remaining 35.6% demonstrated signs of forgetting where an item was placed and frequently suspecting others of theft and concealment of personal items. Conclusion: The symptoms of frequently forgetting new events and the location of personal belongings are of particular concern for families, as they have a propensity to progress and interfere with daily activities. Therefore, the families of affected individuals are expected to identify this symptom early on and present the affected individual for screening or examination at a health care facility. © 2021, Associacao Arquivos de Neuro-Psiquiatria. All rights reserved. |
Alzheimer disease; Dementia; Family; Memory disorders |
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Associacao Arquivos de Neuro-Psiquiatria |
19805764 |
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Article |
Q3 |
540 |
9365 |
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866 |
Lesmana C.R.A., Herjuningtyas C., Inggriani S., Pratiwi Y.E., Lesmana L.A. |
8977683000;57222165389;35329838800;57222163306;55920139300; |
Bedside Percutaneous Approach in a Critically Ill ICU Patient with Complex Pancreatobiliary Disorder Followed by Endoscopic Approach: Lessons Learnt from a Tertiary Referral Center |
2021 |
Case Reports in Gastroenterology |
15 |
1 |
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210 |
217 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101734257&doi=10.1159%2f000513282&partnerID=40&md5=b06514b9ba8afa5ed7ce24173ab5b336 |
Hepatobiliary Division, Department of Internal Medicine, Dr. Cipto Mangunkusumo National General Hospital, Medical Faculty University of Indonesia, Jakarta, Indonesia; Digestive Disease and GI Oncology Center, Medistra Hospital, Jakarta, Indonesia; Department of Anesthesiology, Medistra Hospital, Jakarta, Indonesia; Department of Radiology, Medistra Hospital, Jakarta, Indonesia |
Lesmana, C.R.A., Hepatobiliary Division, Department of Internal Medicine, Dr. Cipto Mangunkusumo National General Hospital, Medical Faculty University of Indonesia, Jakarta, Indonesia, Digestive Disease and GI Oncology Center, Medistra Hospital, Jakarta, Indonesia; Herjuningtyas, C., Department of Anesthesiology, Medistra Hospital, Jakarta, Indonesia; Inggriani, S., Department of Radiology, Medistra Hospital, Jakarta, Indonesia; Pratiwi, Y.E., Digestive Disease and GI Oncology Center, Medistra Hospital, Jakarta, Indonesia; Lesmana, L.A., Digestive Disease and GI Oncology Center, Medistra Hospital, Jakarta, Indonesia |
Pancreatobiliary disorder is a challenging clinical condition, especially when this condition is causing severe infection or biliary sepsis, and sometimes it requires intensive care unit (ICU) treatment. Biliary drainage is the mainstay of therapy; however, the choice of the drainage method is dependent on the patient's clinical condition and the disease itself. A 79-year-old female was transferred on a ventilator to our ICU from another hospital due to biliary sepsis, a large common bile duct stone, and an infected pancreatic pseudocyst. The patient also has other comorbidities such as heart problems, hypothyroidism, and diabetes mellitus. Bedside percutaneous transhepatic biliary drainage without fluoroscopy and percutaneous cyst aspiration was successfully performed, which improved the patient's condition; this was followed by an endoscopic approach, i.e., endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic ultrasound-guided pancreatic pseudocyst drainage. The clinical improvement showed itself in the change of the patient's respiratory status and ventilator mode. In conclusion, the percutaneous approach has a big role in managing critically ill patients in the ICU setting. However, expertise, training experience, and a multidisciplinary team approach are very important for successful management and patient outcome. © 2021 The Author(s). Published by S. Karger AG, Basel. |
Biliary sepsis; Common bile duct stone; Pancreatic pseudocyst; Percutaneous approach |
amikacin; antibiotic agent; bilirubin; C reactive protein; carcinoembryonic antigen; insulin; levothyroxine; piperacillin plus tazobactam; triacylglycerol lipase; aged; Article; artificial ventilation; biliary tract drainage; biliary tract endoscopy; case report; clinical article; common bile duct stone; comorbidity; continuous positive airway pressure; critically ill patient; cyst aspiration; diabetes mellitus; echography; endoscopic retrograde cholangiopancreatography; female; fluoroscopy; human; hypothyroidism; intensive care unit; jaundice; magnetic resonance cholangiopancreatography; pancreas disease; pancreas pseudocyst; sepsis |
S. Karger AG |
16620631 |
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Article |
Q3 |
247 |
16829 |
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922 |
Aman A.T., Wibawa T., Kosasih H., Asdie R.H., Safitri I., Intansari U.S., Mawarti Y., Sudarmono P., Arif M., Puspitasari D., Alisjahbana B., Parwati K.T.M., Gasem M.H., Lokida D., Lukman N., Hartono T.S., Mardian Y., Liang C.J., Siddiqui S., Karyana M., Lau C.-Y. |
6701594071;6507271804;6507043017;23494913500;26647011700;55326687600;57194392139;6507855437;56740206600;37001098000;6506944516;57211545843;6508371601;57190663838;57190737414;57210165041;57196189278;57201642191;8707129300;24449083500;16245242000; |
Etiologies of severe acute respiratory infection (SARI) and misdiagnosis of influenza in Indonesia, 2013-2016 |
2021 |
Influenza and other Respiratory Viruses |
15 |
1 |
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34 |
44 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85087868865&doi=10.1111%2firv.12781&partnerID=40&md5=d277f265cec13ab0a49fac5153d6d8ed |
Department of Microbiology, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada / Dr. Sardjito Hospital, Yogyakarta, Indonesia; Indonesia Research Partnership on Infectious Diseases (INA-RESPOND), Jakarta, Indonesia; Department of Internal Medicine, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada / Dr. Sardjito Hospital, Yogyakarta, Indonesia; Department of Pediatric, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada / Dr. Sardjito Hospital, Yogyakarta, Indonesia; Department of Clinical Pathology, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada / Dr. Sardjito Hospital, Yogyakarta, Indonesia; Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Faculty of Medicine, Universitas Hasanudin / Dr. Wahidin Sudirohusodo Hospital, Makassar, Indonesia; Dr. Soetomo Academic General Hospital, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; Faculty of Medicine, Universitas Padjadjaran / Dr. Hasan Sadikin Hospital, Sumedang, Indonesia; Medical Faculty, Udayana University and Sanglah General Hospital, Denpasar, Indonesia; Dr. Kariadi Hospital / Diponegoro University, Semarang, Indonesia; Tangerang District Hospital, Tangerang, Indonesia; Sulianti Saroso Hospital, Jakarta, Indonesia; National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD, United States; National Institute of Health Research and Development (NIHRD), Ministry of Health, Jakarta, Indonesia |
Aman, A.T., Department of Microbiology, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada / Dr. Sardjito Hospital, Yogyakarta, Indonesia, Indonesia Research Partnership on Infectious Diseases (INA-RESPOND), Jakarta, Indonesia; Wibawa, T., Department of Microbiology, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada / Dr. Sardjito Hospital, Yogyakarta, Indonesia, Indonesia Research Partnership on Infectious Diseases (INA-RESPOND), Jakarta, Indonesia; Kosasih, H., Indonesia Research Partnership on Infectious Diseases (INA-RESPOND), Jakarta, Indonesia; Asdie, R.H., Indonesia Research Partnership on Infectious Diseases (INA-RESPOND), Jakarta, Indonesia, Department of Internal Medicine, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada / Dr. Sardjito Hospital, Yogyakarta, Indonesia; Safitri, I., Indonesia Research Partnership on Infectious Diseases (INA-RESPOND), Jakarta, Indonesia, Department of Pediatric, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada / Dr. Sardjito Hospital, Yogyakarta, Indonesia; Intansari, U.S., Indonesia Research Partnership on Infectious Diseases (INA-RESPOND), Jakarta, Indonesia, Department of Clinical Pathology, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada / Dr. Sardjito Hospital, Yogyakarta, Indonesia; Mawarti, Y., Department of Microbiology, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada / Dr. Sardjito Hospital, Yogyakarta, Indonesia, Indonesia Research Partnership on Infectious Diseases (INA-RESPOND), Jakarta, Indonesia; Sudarmono, P., Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Arif, M., Faculty of Medicine, Universitas Hasanudin / Dr. Wahidin Sudirohusodo Hospital, Makassar, Indonesia; Puspitasari, D., Dr. Soetomo Academic General Hospital, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; Alisjahbana, B., Faculty of Medicine, Universitas Padjadjaran / Dr. Hasan Sadikin Hospital, Sumedang, Indonesia; Parwati, K.T.M., Medical Faculty, Udayana University and Sanglah General Hospital, Denpasar, Indonesia; Gasem, M.H., Dr. Kariadi Hospital / Diponegoro University, Semarang, Indonesia; Lokida, D., Tangerang District Hospital, Tangerang, Indonesia; Lukman, N., Indonesia Research Partnership on Infectious Diseases (INA-RESPOND), Jakarta, Indonesia; Hartono, T.S., Indonesia Research Partnership on Infectious Diseases (INA-RESPOND), Jakarta, Indonesia, Sulianti Saroso Hospital, Jakarta, Indonesia; Mardian, Y., Indonesia Research Partnership on Infectious Diseases (INA-RESPOND), Jakarta, Indonesia; Liang, C.J., National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD, United States; Siddiqui, S., Indonesia Research Partnership on Infectious Diseases (INA-RESPOND), Jakarta, Indonesia, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD, United States; Karyana, M., Indonesia Research Partnership on Infectious Diseases (INA-RESPOND), Jakarta, Indonesia, National Institute of Health Research and Development (NIHRD), Ministry of Health, Jakarta, Indonesia; Lau, C.-Y., Indonesia Research Partnership on Infectious Diseases (INA-RESPOND), Jakarta, Indonesia, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD, United States |
Background: Severe acute respiratory infection (SARI) accounts for a large burden of illness in Indonesia. However, epidemiology of SARI in tertiary hospitals in Indonesia is unknown. This study sought to assess the burden, clinical characteristics, and etiologies of SARI and concordance of clinical diagnosis with confirmed etiology. Methods: Data and samples were collected from subjects presenting with SARI as part of the acute febrile Illness requiring hospitalization study (AFIRE). In tertiary hospitals, clinical diagnosis was ascertained from chart review. Samples were analyzed to determine the “true” etiology of SARI at hospitals and Indonesia Research Partnership on Infectious Diseases (INA-RESPOND) laboratory. Distribution and characteristics of SARI by true etiology and accuracy of clinical diagnosis were assessed. Results: Four hundred and twenty of 1464 AFIRE subjects presented with SARI; etiology was identified in 242 (57.6%), including 121 (28.8%) viruses and bacteria associated with systemic infections, 70 (16.7%) respiratory bacteria and viruses other than influenza virus, and 51 (12.1%) influenza virus cases. None of these influenza patients were accurately diagnosed as having influenza during hospitalization. Conclusions: Influenza was misdiagnosed among all patients presenting with SARI to Indonesian tertiary hospitals in the AFIRE study. Diagnostic approaches and empiric management should be guided by known epidemiology. Public health strategies to address the high burden of influenza should include broad implementation of SARI screening, vaccination programs, clinician education and awareness campaigns, improved diagnostic capacity, and support for effective point-of-care tests. © 2020 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd. |
diagnostic accuracy; etiology; Indonesia; influenza; severe acute respiratory infection |
adolescent; adult; Article; child; demography; diagnostic accuracy; diagnostic error; disease burden; female; hospitalization; human; Indonesia; influenza; information processing; major clinical study; male; measurement accuracy; medical record review; middle aged; priority journal; severe acute respiratory syndrome; tertiary care center; diagnostic error; infant; influenza; Orthomyxoviridae; respiratory tract infection; Diagnostic Errors; Hospitalization; Humans; Indonesia; Infant; Influenza, Human; Orthomyxoviridae; Respiratory Tract Infections |
Blackwell Publishing Ltd |
17502640 |
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32666619 |
Article |
Q1 |
1743 |
1724 |
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