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211 |
Angelin T.C., Bardosono S., Shinta D., Fahmida U. |
57235777300;21933841000;57237520500;14420783500; |
Growth, dietary intake, and vitamin D receptor (VDR) promoter genotype in Indonesian school-age children |
2021 |
Nutrients |
13 |
9 |
2904 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85113740878&doi=10.3390%2fnu13092904&partnerID=40&md5=c7a37360e57bb2d193a5b68571b677d7 |
Southeast Asian Ministers of Education Organization Regional Center for Food and Nutrition (SEAMEO RECFON)-Pusat Kajian Gizi Regional, Universitas Indonesia, Jakarta, 10430, Indonesia; Department of Nutrition, Faculty of Medicine, Universitas Indonesia—Dr. Cipto Mangunkusumo General Hospital, Jakarta, 10430, Indonesia |
Angelin, T.C., Southeast Asian Ministers of Education Organization Regional Center for Food and Nutrition (SEAMEO RECFON)-Pusat Kajian Gizi Regional, Universitas Indonesia, Jakarta, 10430, Indonesia, Department of Nutrition, Faculty of Medicine, Universitas Indonesia—Dr. Cipto Mangunkusumo General Hospital, Jakarta, 10430, Indonesia; Bardosono, S., Department of Nutrition, Faculty of Medicine, Universitas Indonesia—Dr. Cipto Mangunkusumo General Hospital, Jakarta, 10430, Indonesia; Shinta, D., Southeast Asian Ministers of Education Organization Regional Center for Food and Nutrition (SEAMEO RECFON)-Pusat Kajian Gizi Regional, Universitas Indonesia, Jakarta, 10430, Indonesia; Fahmida, U., Southeast Asian Ministers of Education Organization Regional Center for Food and Nutrition (SEAMEO RECFON)-Pusat Kajian Gizi Regional, Universitas Indonesia, Jakarta, 10430, Indonesia |
Nutrition has been known as a predominant factor associated with stunting. However, some studies have discovered a genetic contribution in calcium absorption that will affect growth, known as the VDR gene. The aim of this study was to assess the association between VDR gene polymorphism and dietary intake towards height-for-age z-score (HAZ) of elementary school children in Malang District, East Java. This study analyzed the baseline of a randomized trial in East Java, Indonesia. School children aged 8–10 years old (n = 142) were included in this study. Energy, protein, calcium, and vitamin D intakes were obtained using 4-day 24-h dietary recalls. Two SNPs located in the promoter region of VDR gene were selected (rs11568820 and rs4516035) and analyzed using Real-Time PCR. The result showed a significant correlation between energy and protein intake with HAZ of the children (p = 0.030 and p = 0.016, respectively). The association between VDR gene and HAZ was not found (p > 0.05). Adjusted by other factors, protein intake was significantly correlated with HAZ (β = 0.034, 95% CI 0.015–0.052, p < 0.001, adj. R2 = 0.089). The children in our study had a favorable VDR gene genotype, however the effect of VDR gene promoter activity might not be revealed due to very low vitamin D and calcium intake to stimulate intestinal calcium absorption which in turn affects HAZ. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
Calcium; Children; Dietary intake; Height-for-age z-score (HAZ); Indonesia; Stunting; VDR gene; Vitamin D |
calcium; DNA; protein; vitamin D; vitamin D receptor; calcitriol receptor; vitamin D; Article; body height; calcium absorption; calcium intake; caloric intake; child; child growth; controlled study; correlational study; cross-sectional study; diarrhea; dietary intake; elementary student; female; food frequency questionnaire; gene frequency; genetic variability; genotype; helminthiasis; heterozygote; human; Indonesia; macronutrient intake; male; micronutrient intake; pathogenesis; prevalence; primary school; promoter region; protein intake; randomized controlled trial; real time polymerase chain reaction; respiratory tract infection; school child; semi quantitative food frequency questionnaire; single nucleotide polymorphism; stunting; sun exposure; sunlight; vitamin intake; administration |
MDPI |
20726643 |
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34578782 |
Article |
Q1 |
1418 |
2497 |
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212 |
Librianto D., Aprilya D. |
57192894799;57193710642; |
Cantilever method for severe kyphotic deformity correction in spondylitis tuberculosis: A technical note and literature review |
2021 |
Annals of Medicine and Surgery |
69 |
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102764 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85113387050&doi=10.1016%2fj.amsu.2021.102764&partnerID=40&md5=65a7cd7e9c389e8ea978726e602d9fe3 |
Department of Orthopedic and Traumatology, Faculty of Medicine Universitas Indonesia, Fatmawati General Hospital, Jakarta, Indonesia; Department of Orthopedic and Traumatology, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Librianto, D., Department of Orthopedic and Traumatology, Faculty of Medicine Universitas Indonesia, Fatmawati General Hospital, Jakarta, Indonesia; Aprilya, D., Department of Orthopedic and Traumatology, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Background: The kyphotic deformity is more than just a cosmetic disfigurement. It is potentially life-threatening and disturbs the quality of life by causing cardiopulmonary dysfunction, spinal imbalance, and other associated problems. Corrective surgery is challenging but it is needed to bring the spinal balance back thus halting the progressiveness of the deformity. The cantilever technique is a gold standard to correct the sagittal plane deformity. Methods: This is a review article with some case illustrations from Author's experience. Objective: We aim to review the cantilever technique for kyphotic correction in spondylitis tuberculosis patients. Conclusion: The cantilever technique is the standard for sagittal plane deformity correction that can be applied for kyphotic deformity correction in spondylitis tuberculosis cases. Developing the safest techniques and instrumentation is crucial to achieving spinal balance with minimal risk of morbidities. © 2021 |
Cantilever method; Deformity correction; Kyphotic deformity; Spondylitis tuberculosis |
cosmetic; backache; biopsy; bone graft; cardiopulmonary insufficiency; comorbidity; decortication; deformity; follow up; gold standard; graft failure; human; kyphosis; laminectomy; morbidity; nerve injury; nuclear magnetic resonance imaging; osteotomy; pain; quality of life; Review; screw loosening; spinal cord decompression; spinal cord lesion; spine malformation; systematic review; tissue culture; tuberculous spondylitis; vascularization |
Elsevier Ltd |
20490801 |
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Review |
Q3 |
391 |
12334 |
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213 |
La Distia Nora R., Putera I., Khalisha D.F., Septiana I., Sitompul R. |
56001881000;56485949000;57219417896;57219417256;8312163900; |
The diagnostic value of polymerase chain reaction for ocular tuberculosis diagnosis in relation to antitubercular therapy response: a meta-analysis |
2021 |
International Journal of Infectious Diseases |
110 |
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394 |
402 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85113172042&doi=10.1016%2fj.ijid.2021.07.075&partnerID=40&md5=2517c80887d20c78446a294388261c14 |
Department of Ophthalmology, Faculty of Medicine, University of Indonesia – Cipto Mangunkusumo Kirana Eye HospitalJakarta, Indonesia; Department of Immunology, Erasmus Medical Center, Rotterdam, Netherlands; University of Indonesia Hospital (RSUI), Depok, West Java, Indonesia |
La Distia Nora, R., Department of Ophthalmology, Faculty of Medicine, University of Indonesia – Cipto Mangunkusumo Kirana Eye HospitalJakarta, Indonesia, Department of Immunology, Erasmus Medical Center, Rotterdam, Netherlands, University of Indonesia Hospital (RSUI), Depok, West Java, Indonesia; Putera, I., Department of Ophthalmology, Faculty of Medicine, University of Indonesia – Cipto Mangunkusumo Kirana Eye HospitalJakarta, Indonesia; Khalisha, D.F., Department of Ophthalmology, Faculty of Medicine, University of Indonesia – Cipto Mangunkusumo Kirana Eye HospitalJakarta, Indonesia; Septiana, I., Department of Ophthalmology, Faculty of Medicine, University of Indonesia – Cipto Mangunkusumo Kirana Eye HospitalJakarta, Indonesia; Sitompul, R., Department of Ophthalmology, Faculty of Medicine, University of Indonesia – Cipto Mangunkusumo Kirana Eye HospitalJakarta, Indonesia |
Background: Polymerase chain reaction (PCR) is currently considered the method of choice for diagnosing ocular tuberculosis. However, the sensitivity and specificity of PCR using ocular samples remain uncertain. Our meta-analysis aimed to review the diagnostic accuracy of PCR testing in confirming ocular tuberculosis, with responses to antitubercular therapy (ATT) as reference indices. Methods: A systematic literature search of the PubMed, EBSCOHost, Scopus, and Google Scholar databases was performed using the standardized PRISMA guideline. Observational studies reporting both PCR MTb positivity and ATT response were included. Meta-analysis was performed to estimate the pooled positivity rate, sensitivity, specificity, positive and negative likelihood ratios, diagnostic odds ratios (DOR), and summary receiver operating curves (SROC). Results: The pooled positivity rate for PCR MTb was 0.55 (95% CI 0.44–0.67). The overall sensitivity and specificity were 88% (95% CI 83–92) and 71% (95% CI 60–80), respectively. The pooled DOR was 12.15 (95% CI 5.55–26.62). The area under the SROC was 0.83. Conclusions: The diagnostic accuracy of PCR Mtb is not sufficient for use as a benchmark for ocular TB diagnosis routinely based on ATT response. A negative result may help avoid prescribing unnecessary ATT in dilemmatic cases. © 2021 The Author(s) |
Diagnostic accuracy; Mycobacterium tuberculosis; polymerase chain reaction; uveitis |
ethambutol; ethambutol plus isoniazid plus pyrazinamide plus rifampicin; isoniazid; isoniazid plus rifampicin; pyrazinamide; rifampicin; steroid; tuberculostatic agent; tuberculostatic agent; antibiotic therapy; Article; controlled study; diagnostic accuracy; diagnostic test accuracy study; diagnostic value; false negative result; false positive result; human; inflammation; meta analysis; nonhuman; ocular tuberculosis; polymerase chain reaction; quantitative analysis; receiver operating characteristic; recurrent disease; regression analysis; sensitivity and specificity; serpiginous choroiditis; steroid therapy; systematic review; treatment duration; treatment response; genetics; Mycobacterium tuberculosis; polymerase chain reaction; tuberculosis; Antitubercular Agents; Humans; Mycobacteriu |
Elsevier B.V. |
12019712 |
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34364996 |
Article |
Q1 |
1278 |
2980 |
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214 |
Mecheva M.D.V., Rieger M., Sparrow R., Prafiantini E., Agustina R. |
57226430480;57205307158;57205017055;57193088368;57214141404; |
Snacks, nudges and asymmetric peer influence: Evidence from food choice experiments with children in Indonesia |
2021 |
Journal of Health Economics |
79 |
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102508 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111538660&doi=10.1016%2fj.jhealeco.2021.102508&partnerID=40&md5=652b5bd03857b33eba09516d04a40e6d |
The International Institute of Social Studies (ISS) of Erasmus University Rotterdam, Netherlands; Development Economics Group, Wageningen University, Netherlands; Department of Nutrition, Faculty of Medicine, Universitas Indonesia – Dr Cipto Mangunkusumo General HospitalJakarta, Indonesia; Human Nutrition Research Center, Indonesian Medical Education and Research Institute (HNRC-IMERI), Faculty of Medicine, Universitas Indonesia, Indonesia |
Mecheva, M.D.V., The International Institute of Social Studies (ISS) of Erasmus University Rotterdam, Netherlands; Rieger, M., The International Institute of Social Studies (ISS) of Erasmus University Rotterdam, Netherlands; Sparrow, R., The International Institute of Social Studies (ISS) of Erasmus University Rotterdam, Netherlands, Development Economics Group, Wageningen University, Netherlands; Prafiantini, E., Department of Nutrition, Faculty of Medicine, Universitas Indonesia – Dr Cipto Mangunkusumo General HospitalJakarta, Indonesia, Human Nutrition Research Center, Indonesian Medical Education and Research Institute (HNRC-IMERI), Faculty of Medicine, Universitas Indonesia, Indonesia; Agustina, R., Department of Nutrition, Faculty of Medicine, Universitas Indonesia – Dr Cipto Mangunkusumo General HospitalJakarta, Indonesia, Human Nutrition Research Center, Indonesian Medical Education and Research Institute (HNRC-IMERI), Faculty of Medicine, Universitas Indonesia, Indonesia |
Many children in low- and middle-income countries are growing up during a rapid nutrition transition. Experimental evidence on food choice in developing countries is scarce, while it is unclear to what extent evidence from high-income countries can be generalized. Children participated in a snack choice experiment. We expose some children to emoji labels encouraging healthy snacks, while others observe healthy or unhealthy snacking by peers. While emoji labels moderately promote healthy snacking, the adverse effect of observing a peer eating the unhealthy snack is very large. The effect associated with observing a healthy peer is insignificant. Additionally, cross-randomized blocks of children watched a nutrition video to study the interaction of information provision and nudging. The video independently improves healthy choices but does not aid the emoji nudge and cannot counter the strong negative peer effect. We compare our findings to studies conducted in developed countries and discuss policy implications. © 2021 The Author(s) |
Food choice; Indonesia; Nudges; Overweight; Peer effects |
body mass; child health; food policy; food preference; health expenditure; obesity; public health; adolescent; Article; child; child nutrition; controlled study; decision making; descriptive research; encouragement; fast food; female; human; human experiment; Indonesia; male; nutrition policy; obesity; peer pressure; pilot study; unhealthy diet; feeding behavior; food preference; nutritional status; Indonesia; Child; Feeding Behavior; Food Preferences; Humans; Indonesia; Nutritional Status; Peer Influence; Snacks |
Elsevier B.V. |
01676296 |
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34333202 |
Article |
Q1 |
2676 |
794 |
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215 |
Dilogo I.H., Aditianingsih D., Sugiarto A., Burhan E., Damayanti T., Sitompul P.A., Mariana N., Antarianto R.D., Liem I.K., Kispa T., Mujadid F., Novialdi N., Luviah E., Kurniawati T., Lubis A.M.T., Rahmatika D. |
56161962800;56312263600;57189612291;36058554600;36058523500;57224505288;57194732286;57190862806;55802927800;56515348000;57204398571;57224555404;56114966200;55213290600;15122639800;57474077600; |
Umbilical cord mesenchymal stromal cells as critical COVID-19 adjuvant therapy: A randomized controlled trial |
2021 |
Stem Cells Translational Medicine |
10 |
9 |
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1279 |
1287 |
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8 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85107732762&doi=10.1002%2fsctm.21-0046&partnerID=40&md5=197659d90f645ca5130e69fcf16b7b4d |
Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Stem Cell and Tissue Engineering Research Cluster Indonesian Medical Education and Research Institute (IMERI) Universitas Indonesia, Jakarta, Indonesia; Department of Orthopaedic and Traumatology, Cipto Mangunkusumo General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Anesthesiology and Intensive Care Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Intensive Care Division, Universitas Indonesia Hospital, Depok, Indonesia; Department of Pulmonology and Respiratory Medicine, Faculty of Medicine Universitas Indonesia, Persahabatan General Hospital, Jakarta, Indonesia; Directorate of Medical Services, Nursing and Supporting, Sulianti Saroso Infection Disease Hospital, Jakarta, Indonesia; Directorate of Human Resources Development, Education and Operational Sulianti Saroso Infection Disease Hospital, Jakarta, Indonesia; Department of Histology, Universitas Indonesia Fakultas Kedokteran, Jakarta, Indonesia; Department of Anatomy, Universitas Indonesia Fakultas Kedokteran, Jakarta, Indonesia; Installation of Innovation Management and Intellectual Property, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Dilogo, I.H., Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Stem Cell and Tissue Engineering Research Cluster Indonesian Medical Education and Research Institute (IMERI) Universitas Indonesia, Jakarta, Indonesia, Department of Orthopaedic and Traumatology, Cipto Mangunkusumo General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Aditianingsih, D., Department of Anesthesiology and Intensive Care Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia, Intensive Care Division, Universitas Indonesia Hospital, Depok, Indonesia; Sugiarto, A., Department of Anesthesiology and Intensive Care Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Burhan, E., Department of Pulmonology and Respiratory Medicine, Faculty of Medicine Universitas Indonesia, Persahabatan General Hospital, Jakarta, Indonesia; Damayanti, T., Department of Pulmonology and Respiratory Medicine, Faculty of Medicine Universitas Indonesia, Persahabatan General Hospital, Jakarta, Indonesia; Sitompul, P.A., Directorate of Medical Services, Nursing and Supporting, Sulianti Saroso Infection Disease Hospital, Jakarta, Indonesia; Mariana, N., Directorate of Human Resources Development, Education and Operational Sulianti Saroso Infection Disease Hospital, Jakarta, Indonesia; Antarianto, R.D., Stem Cell and Tissue Engineering Research Cluster Indonesian Medical Education and Research Institute (IMERI) Universitas Indonesia, Jakarta, Indonesia, Department of Histology, Universitas Indonesia Fakultas Kedokteran, Jakarta, Indonesia; Liem, I.K., Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Stem Cell and Tissue Engineering Research Cluster Indonesian Medical Education and Research Institute (IMERI) Universitas Indonesia, Jakarta, Indonesia, Department of Anatomy, Universitas Indonesia Fakultas Kedokteran, Jakarta, Indonesia; Kispa, T., Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Mujadid, F., Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Novialdi, N., Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Luviah, E., Stem Cell and Tissue Engineering Research Cluster Indonesian Medical Education and Research Institute (IMERI) Universitas Indonesia, Jakarta, Indonesia; Kurniawati, T., Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Lubis, A.M.T., Department of Orthopaedic and Traumatology, Cipto Mangunkusumo General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Installation of Innovation Management and Intellectual Property, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rahmatika, D., Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
One of the main causes of acute respiratory distress syndrome in coronavirus disease 2019 (COVID-19) is cytokine storm, although the exact cause is still unknown. Umbilical cord mesenchymal stromal cells (UC-MSCs) influence proinflammatory T-helper 2 (Th2) cells to shift to an anti-inflammatory agent. To investigate efficacy of UC-MSC administration as adjuvant therapy in critically ill patients with COVID-19, we conducted a double-blind, multicentered, randomized controlled trial at four COVID-19 referral hospitals in Jakarta, Indonesia. This study included 40 randomly allocated critically ill patients with COVID-19; 20 patients received an intravenous infusion of 1 × 106/kg body weight UC-MSCs in 100 ml saline (0.9%) solution (SS) and 20 patients received 100 ml 0.9% SS as the control group. All patients received standard therapy. The primary outcome was measured by survival rate and/or length of ventilator usage. The secondary outcome was measured by clinical and laboratory improvement, with serious adverse events. Our study showed the survival rate in the UC-MSCs group was 2.5 times higher than that in the control group (P =.047), which is 10 patients and 4 patients in the UC-MSCs and control groups, respectively. In patients with comorbidities, UC-MSC administration increased the survival rate by 4.5 times compared with controls. The length of stay in the intensive care unit and ventilator usage were not statistically significant, and no adverse events were reported. The application of infusion UC-MSCs significantly decreased interleukin 6 in the recovered patients (P =.023). Therefore, application of intravenous UC-MSCs as adjuvant treatment for critically ill patients with COVID-19 increases the survival rate by modulating the immune system toward an anti-inflammatory state. © 2021 The Authors. STEM CELLS TRANSLATIONAL MEDICINE published by Wiley Periodicals LLC on behalf of AlphaMed Press. |
adjuvants; cord stem cell transplantation; COVID-19; cytokine release syndrome; immunology; mesenchymal stromal cells |
5' nucleotidase; azithromycin; C reactive protein; CD34 antigen; CD4 antigen; CD56 antigen; CD8 antigen; chemokine receptor CXCR3; D dimer; ferritin; fibrinogen; hemoglobin; interleukin 10; interleukin 6; lactic acid; leukemia inhibitory factor; oseltamivir; procalcitonin; Thy 1 membrane glycoprotein; vasculotropin; adjuvant therapy; adult; adult respiratory distress syndrome; Article; artificial ventilation; blood cell count; clinical article; clinical decision making; computer assisted tomography; controlled study; coronavirus disease 2019; critically ill patient; cytokine release syndrome; cytokine storm; double blind procedure; female; flow cytometry; fluid resuscitation; ground glass opacity; hematocrit; Horowitz index; human; hypotension; intensive care unit; length of stay; leukopen |
John Wiley and Sons Ltd |
21576564 |
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34102020 |
Article |
Q1 |
1781 |
1654 |
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216 |
Pawankar R., Thong B.Y.-H., Tiongco-Recto M., Wang J.-Y., Abdul Latiff A.H., Thien F., Oh J.-W., Kamchaisatian W., Rengganis I., Udwadia Z.F., Dhar R., Munkhbayarlakh S., Narantsetseg L., Le Pham D., Leung T.F., Zhang L., APAAACI COVID-19 Working Group |
7005904460;6603816215;55359899500;56499349900;55608026700;57204250177;55657464600;6505855073;8449988000;57192641184;7006700626;56800881300;8977752900;57201431490;57225672394;36068675900; |
Asia-Pacific perspectives on the COVID-19 pandemic |
2021 |
Allergy: European Journal of Allergy and Clinical Immunology |
76 |
9 |
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2998 |
2901 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85106213191&doi=10.1111%2fall.14894&partnerID=40&md5=a8dda5140c82a54f09e8a12b2804a47c |
Division of Allergy, Department of Pediatrics, Nippon Medical School, Tokyo, Japan; Department of Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, Singapore City, Singapore; Division of Allergy and Immunology, Department of Pediatrics, University of the Philippines-Philippine General Hospital, Manila, Philippines; Centre of Allergy and Clinical Immunology Research (ACIR), Department of Paediatrics, National Cheng Kung University Hospital, Tainan, Taiwan; Allergy & Immunology Centre Pantai Hospital, Kuala Lumpur, Malaysia; Department of Paediatrics, Universiti Putra Malaysia Teaching Hospital, Kuala Lumpur, Malaysia; Eastern Health, Monash University, Melbourne, Vic, Australia; Department of Pediatrics, Hanyang University Guri Hospital, Guri, Gyunggi-Do, South Korea; Pediatric Allergy and Immunology Division, Samitivej Children’s Hospital, Bangkok, Thailand; Division of Allergy and Clinical Immunology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, CiptoMangunkusumo General Hopsital, Jakarta, Indonesia; P.D. Hinduja National Hospital and Medical Research Centre and the Breach Candy Hospital, Mumbai, India; Department of Pulmonology, C K BIRLA Group of Hospitals, CMRIKolkata, India; Department of Pulmonology and Allergology, School of Medicine, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia; Department of Biochemistry, School of Biomedicine, MongolianNational University of Medical Sciences, Ulaanbaatar, Mongolia; Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Viet Nam; Department of Pediatrics, Chinese University of Hong Kong, Hong Kong; Department of Otolaryngology Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China |
Pawankar, R., Division of Allergy, Department of Pediatrics, Nippon Medical School, Tokyo, Japan; Thong, B.Y.-H., Department of Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, Singapore City, Singapore; Tiongco-Recto, M., Division of Allergy and Immunology, Department of Pediatrics, University of the Philippines-Philippine General Hospital, Manila, Philippines; Wang, J.-Y., Centre of Allergy and Clinical Immunology Research (ACIR), Department of Paediatrics, National Cheng Kung University Hospital, Tainan, Taiwan; Abdul Latiff, A.H., Allergy & Immunology Centre Pantai Hospital, Kuala Lumpur, Malaysia, Department of Paediatrics, Universiti Putra Malaysia Teaching Hospital, Kuala Lumpur, Malaysia; Thien, F., Eastern Health, Monash University, Melbourne, Vic, Australia; Oh, J.-W., Department of Pediatrics, Hanyang University Guri Hospital, Guri, Gyunggi-Do, South Korea; Kamchaisatian, W., Pediatric Allergy and Immunology Division, Samitivej Children’s Hospital, Bangkok, Thailand; Rengganis, I., Division of Allergy and Clinical Immunology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, CiptoMangunkusumo General Hopsital, Jakarta, Indonesia; Udwadia, Z.F., P.D. Hinduja National Hospital and Medical Research Centre and the Breach Candy Hospital, Mumbai, India; Dhar, R., Department of Pulmonology, C K BIRLA Group of Hospitals, CMRIKolkata, India; Munkhbayarlakh, S., Department of Pulmonology and Allergology, School of Medicine, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia; Narantsetseg, L., Department of Biochemistry, School of Biomedicine, MongolianNational University of Medical Sciences, Ulaanbaatar, Mongolia; Le Pham, D., Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Viet Nam; Leung, T.F., Department of Pediatrics, Chinese University of Hong Kong, Hong Kong; Zhang, L., Department of Otolaryngology Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China; APAAACI COVID-19 Working Group |
[No abstract available] |
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biological product; chloroquine; convalescent plasma; corticosteroid; hydroxychloroquine; immunosuppressive agent; lopinavir plus ritonavir; remdesivir; tocilizumab; asthma; chronic rhinosinusitis; coronavirus disease 2019; desensitization; device infection; eye allergy; health care access; health care policy; health care survey; human; immunosuppressive treatment; infection control; infection prevention; latex allergy; Letter; medical device complication; mutation; pandemic; phenotype; protective glasses; questionnaire; Asia; epidemiology; pandemic; Asia; COVID-19; Humans; Pandemics; SARS-CoV-2 |
John Wiley and Sons Inc |
01054538 |
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33948966 |
Letter |
Q1 |
3363 |
542 |
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217 |
Kurnia K.H., Elvioza, Sidik M., Sari T.T., Prihartono J., Sitorus R.S. |
57222405280;57205416912;56252760000;36519483600;6602605635;57221587271; |
Novel retinal findings in β-thalassemia major: older age and higher ferritin level as the risk factors |
2021 |
Graefe's Archive for Clinical and Experimental Ophthalmology |
259 |
9 |
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2633 |
2641 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102635685&doi=10.1007%2fs00417-021-05141-z&partnerID=40&md5=bf7abc1182072dd50cdf5ec7be6fa742 |
Department of Ophthalmology, Faculty of Medicine Universitas Indonesia - Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Department of Child Health, Faculty of Medicine Universitas Indonesia - Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Department of Community Medicine, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Kurnia, K.H., Department of Ophthalmology, Faculty of Medicine Universitas Indonesia - Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Elvioza, Department of Ophthalmology, Faculty of Medicine Universitas Indonesia - Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Sidik, M., Department of Ophthalmology, Faculty of Medicine Universitas Indonesia - Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Sari, T.T., Department of Child Health, Faculty of Medicine Universitas Indonesia - Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Prihartono, J., Department of Community Medicine, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Sitorus, R.S., Department of Ophthalmology, Faculty of Medicine Universitas Indonesia - Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia |
Purpose: To investigate retinal changes in β-thalassemia major patients and identify their association with systemic risk factors. Methods: In this prospective study, 120 β-thalassemia major patients received complete ophthalmic examinations (best-corrected visual acuity, contrast sensitivity, color vision, and indirect ophthalmoscopy) and retinal imaging using color fundus photography and fundus autofluorescence imaging. Patients were grouped according to the presence of thalassemia-related retinal changes. The association between systemic risk factors (age, type and duration of iron chelator use, history of splenectomy, hemoglobin level, and ferritin level) and thalassemia-related retinal changes was investigated using logistic regression analysis. Results: Thalassemia-related retinal changes were identified in 36.7% of patients. Several distinct retinal changes were observed, including retinal refractile bodies in 10% of patients and retinal hemorrhage in 5.8% of patients. Fundus autofluorescence imaging showed abnormal patterns in 36.3% of patients with thalassemia-related retinal changes and 18.4% of patients without thalassemia-related retinal changes. Age (odds ratio [OR] = 1.10, 95% confidence interval [CI] 1.03–1.18) and ferritin level (OR 1.16, 95% CI 1.01–1.33) were associated with thalassemia-related retinal changes. Conclusion: Novel retinal changes were observed in β-thalassemia major patients. This study identified older age and higher ferritin level as risk factors for thalassemia-related retinal changes. © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature. |
Ferritin; Fundus autofluorescence imaging; Iron chelator; Retinal changes; β-Thalassemia major |
deferasirox; deferiprone; deferoxamine; ferritin; hemoglobin; ferritin; adult; age; angioid streak; Article; autofluorescence imaging; best corrected visual acuity; blood transfusion; branch retinal vein occlusion; color vision; contrast sensitivity; controlled study; drusen; epithelium hyperplasia; eye fundus; eye photography; female; ferritin blood level; hemoglobin blood level; human; Indonesia; major clinical study; male; melanocytosis; observational study; ophthalmoscopy; optic disk anomaly; optical coherence tomography; papilledema; patient history of surgery; prospective study; retina disease; retina examination; retina hemorrhage; retina pigment degeneration; slit lamp microscopy; splenectomy; subretinal neovascularization; thalassemia major; treatment duration; aged; beta thalasse |
Springer Science and Business Media Deutschland GmbH |
0721832X |
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33738624 |
Article |
Q1 |
1196 |
3322 |
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218 |
Fachniadin A., Widi Nugroho S., Ananda Aman R., Ichwan S., Tandian D., Susanto E., Watanabe K., Nonaka Y. |
57222123314;57219659664;57222125502;57192906639;57192891173;57204423225;55704851200;36344004800; |
A Dumbbell-shaped hypoglossal schwannoma managed by a combination of open surgery and endoscopic assistance |
2021 |
Interdisciplinary Neurosurgery: Advanced Techniques and Case Management |
25 |
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101102 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101531664&doi=10.1016%2fj.inat.2021.101102&partnerID=40&md5=aa132c91fdc36c35a156948ab70bdf91 |
Department of Neurosurgery, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Department of Anatomic Pathology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Department of Neurosurgery, Tokyo Jikei University School of Medicine, Tokyo, Japan; Department of Neurosurgery, Tokai University School of Medicine, Tokyo, Japan |
Fachniadin, A., Department of Neurosurgery, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Widi Nugroho, S., Department of Neurosurgery, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Ananda Aman, R., Department of Neurosurgery, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Ichwan, S., Department of Neurosurgery, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Tandian, D., Department of Neurosurgery, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Susanto, E., Department of Anatomic Pathology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Watanabe, K., Department of Neurosurgery, Tokyo Jikei University School of Medicine, Tokyo, Japan; Nonaka, Y., Department of Neurosurgery, Tokai University School of Medicine, Tokyo, Japan |
Background: Hypoglossal schwannoma is a rare benign tumor that comprises about 5% of all intracranial schwannoma. Surgical management for hypoglossal schwannoma is still evolving along with our understanding of neuroanatomy and surgical equipment improvement, especially endoscopy. The far lateral transcondylar approach is commonly used for hypoglossal schwannomas. This traditional approach requires great effort and is considered a lengthy procedure. The use of endoscopy gives an additional advantage to microscopic surgery in managing this tumor, making surgery less complicated and faster. Combining the microscope and endoscope is an effective way to operate in small corridors. Case: In a stepwise fashion, we present a case of a 53-year-old female with hypoglossal schwannoma, which was successfully resected using a retrosigmoid transcondylar approach with endoscopic assistance. Conclusion: A retrosigmoid transcondylar approach with endoscopic assistance is an excellent option in surgical management for hypoglossal schwannoma. Both microscopic and endoscopic approaches will be gaining more usefulness in managing skull base tumors and should be used collaboratively. © 2021 The Authors |
Dumbbell-shaped; Endoscopic; Hypoglossal schwannoma; Retrosigmoid transcondylar |
corticosteroid; fibrin glue; accessory nerve; adult; Article; brain stem; breathing exercise; cancer surgery; case report; cerebral revascularization; chemodectoma; chondroma; clinical article; clinical examination; cranial nerve; craniotomy; differential diagnosis; Doppler flowmetry; drinking; dysphagia; eating; female; histopathology; hoarseness; hospital discharge; human; hypoglossal nerve; intraoperative monitoring; intraoperative neurophysiological monitoring; jugular foramen; liquorrhea; mastoid; medulla oblongata; meningioma; middle aged; mitosis rate; muscle atrophy; neurilemoma; neuroanatomy; neuroendoscopy; neuroimaging; neuromonitoring; neurorehabilitation; nuclear magnetic resonance imaging; open surgery; paraganglioma; paralysis; parapharyngeal space; periosteum; physical exam |
Elsevier B.V. |
22147519 |
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Article |
Q4 |
202 |
19207 |
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219 |
Amarra M.S., Chong M.F.-F., Titapant V., Somprasit C., Rogacion J., Irwinda R., Huynh T.N.K., Nalliah S. |
26024123300;16302916300;6602085502;8440614700;6508291071;57205713130;57221814418;25422423000; |
ILSI Southeast Asia symposium: prevalence, risk factors, and actions to address gestational diabetes in selected Southeast Asian countries |
2021 |
European Journal of Clinical Nutrition |
75 |
9 |
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1303 |
1308 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100287487&doi=10.1038%2fs41430-020-00838-6&partnerID=40&md5=968eff6db95c2d745843171831db19e3 |
Department of Food Science and Nutrition, College of Home Economics, University of the Philippines Diliman, Quezon, Philippines; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore; Department of Obstetrics and Gynecology, Faculty of Medicine, Siriraj Hospital Mahidol University, Bangkok, Thailand; Department of Obstetrics and Gynecology, Faculty of Medicine, Thammasat University, Bangkok, Thailand; Department of Pediatrics, University of the Philippines, Manila, Philippines; Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Obstetrics and Gynecology, Pham Ngoc Thach University of Medicine, Ho Chi Minh, Viet Nam; Division of Obstetrics & Gynaecology, Clinical School, International Medical University, Seremban, Malaysia |
Amarra, M.S., Department of Food Science and Nutrition, College of Home Economics, University of the Philippines Diliman, Quezon, Philippines; Chong, M.F.-F., Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore; Titapant, V., Department of Obstetrics and Gynecology, Faculty of Medicine, Siriraj Hospital Mahidol University, Bangkok, Thailand; Somprasit, C., Department of Obstetrics and Gynecology, Faculty of Medicine, Thammasat University, Bangkok, Thailand; Rogacion, J., Department of Pediatrics, University of the Philippines, Manila, Philippines; Irwinda, R., Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Huynh, T.N.K., Department of Obstetrics and Gynecology, Pham Ngoc Thach University of Medicine, Ho Chi Minh, Viet Nam; Nalliah, S., Division of Obstetrics & Gynaecology, Clinical School, International Medical University, Seremban, Malaysia |
[No abstract available] |
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trace element; anthropometry; Brunei Darussalam; Cambodia; diet therapy; dietary intake; female; gestational weight gain; health care planning; human; Indonesia; Laos; Malaysia; Myanmar; nutritional assessment; Philippines; physical activity; practice guideline; pregnancy diabetes mellitus; prevalence; Review; risk factor; risk reduction; Singapore; Southeast Asian; symposium; Thailand; Viet Nam; pregnancy; pregnancy diabetes mellitus; Southeast Asia; Asia, Southeastern; Diabetes, Gestational; Female; Humans; Pregnancy; Prevalence; Risk Factors |
Springer Nature |
09543007 |
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33531635 |
Review |
Q1 |
1024 |
4241 |
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220 |
Castro-Calvo J., King D.L., Stein D.J., Brand M., Carmi L., Chamberlain S.R., Demetrovics Z., Fineberg N.A., Rumpf H.-J., Yücel M., Achab S., Ambekar A., Bahar N., Blaszczynski A., Bowden-Jones H., Carbonell X., Chan E.M.L., Ko C.-H., de Timary P., Dufour M., Grall-Bronnec M., Lee H.K., Higuchi S., Jimenez-Murcia S., Király O., Kuss D.J., Long J., Müller A., Pallanti S., Potenza M.N., Rahimi-Movaghar A., Saunders J.B., Schimmenti A., Lee S.-Y., Siste K., Spritzer D.T., Starcevic V., Weinstein A.M., Wölfling K., Billieux J. |
55883443800;57214845145;55769747595;7202584047;56059576800;24723599200;55882733400;35413253200;7004528536;7006258831;43860942100;35749590300;56118752900;57220353000;15834239200;35232657000;35344453600;8716479100;25821757600;7103106444;57209334001;8600274900;7202930847;7801631922;57000322900;41762055600;57190689045;56472199900;57207496581;7006591634;8696686900;7402341830;36089370500;36760834000;55644113100;24463790800;7005374306;7201680411;23973806500;57220421868; |
Expert appraisal of criteria for assessing gaming disorder: an international Delphi study |
2021 |
Addiction |
116 |
9 |
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2463 |
2475 |
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24 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099942594&doi=10.1111%2fadd.15411&partnerID=40&md5=284445a20e0a947af8166f3091d96aea |
Department of Personality, Assessment, and Psychological Treatments, University of Valencia, Spain; College of Education, Psychology, and Social Work, Flinders University, Australia; SAMRC Unit on Risk and Resilience in Mental Disorders, Department of Psychiatry and Neuroscience Institute, University of Cape Town, Cape Town, South Africa; General Psychology: Cognition and Center for Behavioral Addiction Research (CeBAR), University Duisburg-Essen, Germany; The Data Science Institute, Inter-disciplinary Center, Herzliya, Israel; Department of Psychiatry, Faculty of Medicine, University of Southampton, Southampton, United Kingdom; Southern Health NHS Foundation Trust, Southampton, United Kingdom; Institute of Psychology, ELTE Eötvös Loránd University, Budapest, Hungary; University of Hertfordshire, Hatfield, UK, Hertfordshire Partnership University NHS Foundation Trust, Welwyn Garden City, United Kingdom; University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom; Department of Psychiatry and Psychotherapy, University of Luebeck, Luebeck, Germany; BrainPark, School of Psychological Sciences, Turner Institute for Brain and Mental Health and Monash Biomedical Imaging Facility, Monash University, Melbourne, VIC, Australia; Specialized Facility In Behavioral Addictions, ReConnecte, Department of Psychiatry, University Hospitals of Geneva, Generva, Switzerland; Faculty of Medicine, Geneva University, Geneva, Switzerland; National Drug Dependence Treatment Centre, All India Institute of Medical Sciences, New Delhi, India; Department of Psychiatry and Mental Health, Hospital Selayang, Ministry of Health, Malaysia; Faculty of Science, Brain and Mind Centre, School of Psychology, University of Sydney, Sydney, Australia; National Centre for Gaming Disorders, London, United Kingdom; University College London, London, United Kingdom; Faculty of Psychology, Education and Sports Sciences Blanquerna, Ramon Llull University, Barcelona, Spain; St John's Cathedral Counselling Service, and Division on Addiction, Hong Kong; Department of Psychiatry, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung City, Taiwan; Department of Adult Psychiatry, Institute of Neuroscience, UCLouvain and Cliniques Universitaires Saint-Luc, Brussels, Belgium; Université du Québec à Montréal, Montréal, QC, Canada; CHU Nantes, Department of Addictology and Psychiatry, Nantes, France; Universités de Nantes et Tours, UMR 1246, Nantes, France; Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, South Korea; National Hospital Organization, Kurihama Medical and Addiction Center, Japan; Department of Psychiatry, Bellvitge University Hospital-IDIBELL, Barcelona, Spain; Ciber Fisiopatología Obesidad y Nutrición (CIBERObn), Instituto de Salud Carlos III, Madrid, Spain; International Gaming Research Unit, Psychology Department, Nottingham Trent University, Nottingham, United Kingdom; Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Laboratory for Experimental Psychopathology, Psychological Science Research Institute, Université Catholique de Louvain, Louvain, Belgium; Department of Psychosomatic Medicine and Psychotherapy, Hannover Medical School, Hanover, Germany; Neuroscience Institute, University of Florence, Italy; Departments of Psychiatry and Neuroscience and the Child Study Center, Yale School of Medicine and Connecticut Mental Health Center, New Haven, CT, United States; Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran; Centre for Youth Substance Abuse Research, University of Queensland, Brisbane, QLD, Australia; Faculty of Human and Social Sciences, Kore University of Enna, Enna, Italy; Department of Psychiatry, Eunpyeong St Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea; Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Postgraduate Program in Psychiatry and Behavioral Sciences, Federal University of Rio Grande do Sul, Brazil; Faculty of Medicine and Health, Sydney Medical School, Nepean Clinical School, University of Sydney, Sydney, Australia; Department of Behavioral Science, Ariel University, Israel; Outpatient Clinic for Behavioral Addictions, Department of Psychosomatic Medicine and Psychotherapy, University Medical Center of the Johannes Gutenberg-University Mainz, Germany; Institute of Psychology, University of Lausanne, Lausanne, Switzerland; Health and Behaviour Institute, University of Luxembourg, Esch-sur-Alzette, Luxembourg |
Castro-Calvo, J., Department of Personality, Assessment, and Psychological Treatments, University of Valencia, Spain; King, D.L., College of Education, Psychology, and Social Work, Flinders University, Australia; Stein, D.J., SAMRC Unit on Risk and Resilience in Mental Disorders, Department of Psychiatry and Neuroscience Institute, University of Cape Town, Cape Town, South Africa; Brand, M., General Psychology: Cognition and Center for Behavioral Addiction Research (CeBAR), University Duisburg-Essen, Germany; Carmi, L., The Data Science Institute, Inter-disciplinary Center, Herzliya, Israel; Chamberlain, S.R., Department of Psychiatry, Faculty of Medicine, University of Southampton, Southampton, United Kingdom, Southern Health NHS Foundation Trust, Southampton, United Kingdom; Demetrovics, Z., Institute of Psychology, ELTE Eötvös Loránd University, Budapest, Hungary; Fineberg, N.A., University of Hertfordshire, Hatfield, UK, Hertfordshire Partnership University NHS Foundation Trust, Welwyn Garden City, United Kingdom, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom; Rumpf, H.-J., Department of Psychiatry and Psychotherapy, University of Luebeck, Luebeck, Germany; Yücel, M., BrainPark, School of Psychological Sciences, Turner Institute for Brain and Mental Health and Monash Biomedical Imaging Facility, Monash University, Melbourne, VIC, Australia; Achab, S., Specialized Facility In Behavioral Addictions, ReConnecte, Department of Psychiatry, University Hospitals of Geneva, Generva, Switzerland, Faculty of Medicine, Geneva University, Geneva, Switzerland; Ambekar, A., National Drug Dependence Treatment Centre, All India Institute of Medical Sciences, New Delhi, India; Bahar, N., Department of Psychiatry and Mental Health, Hospital Selayang, Ministry of Health, Malaysia; Blaszczynski, A., Faculty of Science, Brain and Mind Centre, School of Psychology, University of Sydney, Sydney, Australia; Bowden-Jones, H., National Centre for Gaming Disorders, London, United Kingdom, University College London, London, United Kingdom; Carbonell, X., Faculty of Psychology, Education and Sports Sciences Blanquerna, Ramon Llull University, Barcelona, Spain; Chan, E.M.L., St John's Cathedral Counselling Service, and Division on Addiction, Hong Kong; Ko, C.-H., Department of Psychiatry, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung City, Taiwan; de Timary, P., Department of Adult Psychiatry, Institute of Neuroscience, UCLouvain and Cliniques Universitaires Saint-Luc, Brussels, Belgium; Dufour, M., Université du Québec à Montréal, Montréal, QC, Canada; Grall-Bronnec, M., CHU Nantes, Department of Addictology and Psychiatry, Nantes, France, Universités de Nantes et Tours, UMR 1246, Nantes, France; Lee, H.K., Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, South Korea; Higuchi, S., National Hospital Organization, Kurihama Medical and Addiction Center, Japan; Jimenez-Murcia, S., Department of Psychiatry, Bellvitge University Hospital-IDIBELL, Barcelona, Spain, Ciber Fisiopatología Obesidad y Nutrición (CIBERObn), Instituto de Salud Carlos III, Madrid, Spain; Király, O., Institute of Psychology, ELTE Eötvös Loránd University, Budapest, Hungary; Kuss, D.J., International Gaming Research Unit, Psychology Department, Nottingham Trent University, Nottingham, United Kingdom; Long, J., Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China, Laboratory for Experimental Psychopathology, Psychological Science Research Institute, Université Catholique de Louvain, Louvain, Belgium; Müller, A., Department of Psychosomatic Medicine and Psychotherapy, Hannover Medical School, Hanover, Germany; Pallanti, S., Neuroscience Institute, University of Florence, Italy; Potenza, M.N., Departments of Psychiatry and Neuroscience and the Child Study Center, Yale School of Medicine and Connecticut Mental Health Center, New Haven, CT, United States; Rahimi-Movaghar, A., Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran; Saunders, J.B., Centre for Youth Substance Abuse Research, University of Queensland, Brisbane, QLD, Australia; Schimmenti, A., Faculty of Human and Social Sciences, Kore University of Enna, Enna, Italy; Lee, S.-Y., Department of Psychiatry, Eunpyeong St Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea; Siste, K., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Spritzer, D.T., Postgraduate Program in Psychiatry and Behavioral Sciences, Federal University of Rio Grande do Sul, Brazil; Starcevic, V., Faculty of Medicine and Health, Sydney Medical School, Nepean Clinical School, University of Sydney, Sydney, Australia; Weinstein, A.M., Department of Behavioral Science, Ariel University, Israel; Wölfling, K., Outpatient Clinic for Behavioral Addictions, Department of Psychosomatic Medicine and Psychotherapy, University Medical Center of the Johannes Gutenberg-University Mainz, Germany; Billieux, J., Institute of Psychology, University of Lausanne, Lausanne, Switzerland, Health and Behaviour Institute, University of Luxembourg, Esch-sur-Alzette, Luxembourg |
Background and aims: Following the recognition of ‘internet gaming disorder’ (IGD) as a condition requiring further study by the DSM-5, ‘gaming disorder’ (GD) was officially included as a diagnostic entity by the World Health Organization (WHO) in the 11th revision of the International Classification of Diseases (ICD-11). However, the proposed diagnostic criteria for gaming disorder remain the subject of debate, and there has been no systematic attempt to integrate the views of different groups of experts. To achieve a more systematic agreement on this new disorder, this study employed the Delphi expert consensus method to obtain expert agreement on the diagnostic validity, clinical utility and prognostic value of the DSM-5 criteria and ICD-11 clinical guidelines for GD. Methods: A total of 29 international experts with clinical and/or research experience in GD completed three iterative rounds of a Delphi survey. Experts rated proposed criteria in progressive rounds until a pre-determined level of agreement was achieved. Results: For DSM-5 IGD criteria, there was an agreement both that a subset had high diagnostic validity, clinical utility and prognostic value and that some (e.g. tolerance, deception) had low diagnostic validity, clinical utility and prognostic value. Crucially, some DSM-5 criteria (e.g. escapism/mood regulation, tolerance) were regarded as incapable of distinguishing between problematic and non-problematic gaming. In contrast, ICD-11 diagnostic guidelines for GD (except for the criterion relating to diminished non-gaming interests) were judged as presenting high diagnostic validity, clinical utility and prognostic value. Conclusions: This Delphi survey provides a foundation for identifying the most diagnostically valid and clinically useful criteria for GD. There was expert agreement that some DSM-5 criteria were not clinically relevant and may pathologize non-problematic patterns of gaming, whereas ICD-11 diagnostic guidelines are likely to diagnose GD adequately and avoid pathologizing. © 2021 The Authors. Addiction published by John Wiley & Sons Ltd on behalf of Society for the Study of Addiction. |
Delphi; diagnosis; DSM; gaming disorder; ICD; internet gaming disorder |
addiction; Delphi study; Diagnostic and Statistical Manual of Mental Disorders; human; impulse control disorder; Internet; video game; Behavior, Addictive; Delphi Technique; Diagnostic and Statistical Manual of Mental Disorders; Disruptive, Impulse Control, and Conduct Disorders; Humans; Internet; Video Games |
John Wiley and Sons Inc |
09652140 |
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33449441 |
Article |
Q1 |
2424 |
961 |
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