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46 |
Martika W., Dilogo I.H., Setyawan R. |
57221741247;56161962800;57206249736; |
Functional outcome in scapular fracture treatment evaluation with 2-year follow-up in Cipto Mangunkusumo Hospital |
2021 |
International Journal of Surgery Open |
37 |
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100425 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85119256972&doi=10.1016%2fj.ijso.2021.100425&partnerID=40&md5=b50a45ce664d7aea0b7dc9549bdde380 |
Department of Orthopaedics and Traumatology, Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Adult Reconstruction, Hip, and Knee Division, Department of Orthopaedics and Traumatology, Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Martika, W., Department of Orthopaedics and Traumatology, Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Dilogo, I.H., Adult Reconstruction, Hip, and Knee Division, Department of Orthopaedics and Traumatology, Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Setyawan, R., Department of Orthopaedics and Traumatology, Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Background: Standard treatment of scapular fractures is still controversial. There was no consensus for the best indication in surgical management and therapeutic choice of the scapular fracture. This study aim is to evaluate both radiological characteristics and functional outcomes between patients with scapular fracture treated with conservative and operative management. Methods: We did a case series study of 19 patients with scapular fractures between 2012 and 2017. Nine patients were treated with open reduction internal fixation and 10 patients were treated conservatively. We evaluated radiological outcome using degree of Glenopolar Angle (GPA), angulation, and medialization through anteroposterior, lateral, and scapular Y projection, functional outcome using DASH scores, and complications in 2-year follow-up. Result: The mean patient age was 46.3 ± 18.4 years in the conservative group and 42.7 ± 11.5 years in the operative group. Fracture pattern was classified using Zdravkovic and Damholt (ZD) classification. DASH Score was excellent with 9.5 ± 2.1 points in conservative group and 6.0 ± 2.5 points in operative group with insignificant difference. There was significant difference in GPA and medialization. This is supported by functional outcome of operative group which is higher compared to conservative treatment insignificantly. Conclusion: Operative treatment resulted high functional outcome and minimal complications compared to the conservative group. Operative treatment was recommended for scapular fractures that are displaced more than 9 mm and/or angulated more than 40°. Level of evidence: II, therapeutic study. © 2021 The Authors |
Conservative treatment; DASH score; Glenopolar angle; Scapular fracture; Surgical treatment; Zdravkovic and damholt classification |
adult; clinical article; clinical outcome; conservative treatment; controlled study; Disabilities of the Arm, Shoulder and Hand (score); female; follow up; functional status; human; intermethod comparison; intraoperative period; male; open reduction (procedure); orthopedic surgery; osteosynthesis; outcome assessment; preoperative evaluation; scapula fracture; Short Survey; shoulder radiography; treatment indication; x-ray computed tomography |
Elsevier Ltd |
24058572 |
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Short Survey |
Q4 |
187 |
20224 |
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47 |
Craddock N., Garbett K.M., Haywood S., Nasution K., White P., Saraswati L.A., Rizkiah C., Medise B.E., Diedrichs P.C. |
57204036842;56901034200;57339654700;57339654800;55730025700;55842541900;57339370700;57194679894;6504448191; |
‘Dove Confident Me Indonesia: Single Session’: study protocol for a randomised controlled trial to evaluate a school-based body image intervention among Indonesian adolescents |
2021 |
BMC Public Health |
21 |
1 |
2102 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85119148188&doi=10.1186%2fs12889-021-11770-0&partnerID=40&md5=081ebeb058ffd74b7c5312132c820642 |
Centre for Appearance Research, University of the West of England, Coldharbour Lane, Bristol, BS16 1QY, United Kingdom; Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; University of Hawaiʻi at Mānoa, Honolulu, United States; Lazuardi Al Falah Depok Junior High School Indonesia, Kota Depok, Indonesia |
Craddock, N., Centre for Appearance Research, University of the West of England, Coldharbour Lane, Bristol, BS16 1QY, United Kingdom; Garbett, K.M., Centre for Appearance Research, University of the West of England, Coldharbour Lane, Bristol, BS16 1QY, United Kingdom; Haywood, S., Centre for Appearance Research, University of the West of England, Coldharbour Lane, Bristol, BS16 1QY, United Kingdom; Nasution, K., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; White, P., Centre for Appearance Research, University of the West of England, Coldharbour Lane, Bristol, BS16 1QY, United Kingdom; Saraswati, L.A., University of Hawaiʻi at Mānoa, Honolulu, United States; Rizkiah, C., Lazuardi Al Falah Depok Junior High School Indonesia, Kota Depok, Indonesia; Medise, B.E., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Diedrichs, P.C., Centre for Appearance Research, University of the West of England, Coldharbour Lane, Bristol, BS16 1QY, United Kingdom |
Background: Due to the prevalence and associated adverse health consequences of negative body image among adolescents globally, there is a need to develop acceptable, effective, and scalable interventions. School-based body image interventions delivered by trained teachers show promise in reducing negative body image in adolescents. However, there is currently a lack of evidenced-based body image interventions for use in low- and middle-income countries (LMICs). This paper outlines a protocol for the development and evaluation of Dove Confident Me Indonesia: Single Session, a single-session, teacher-led body image intervention for Indonesian adolescents. Method: The effectiveness of the intervention will be evaluated using a cluster randomised controlled trial design. Due to the COVID-19 pandemic, the trial will be conducted online. Trained teachers or school guidance counsellors will deliver the intervention. Self-report questionnaires will be collected at three time points: baseline, post-intervention, and two-month follow-up. The primary outcome is body esteem. Secondary outcomes are internalisation of appearance ideals, mood, engagement in life activities, tendency to engage in appearance comparisons, and skin shade satisfaction. A minimum of 1000 participants will provide 95% power to detect small-to-medium intervention effects. To account for attrition and potential internet issues, the sample will comprise of 2000 Indonesian adolescents in grades 7–9, attending state junior high schools in Surabaya, East Java. Quantitative and qualitative data on acceptability of the intervention will also be collected from teachers and students. Additionally, fidelity of lesson implementation will be assessed. This project received ethical approval from the Universitas Indonesia and the University of the West of England. The intervention will be disseminated in junior high schools throughout Indonesia via UNICEF’s Life Skills Education (LSE) programme, which will be freely available for teachers to download. Discussion: This paper presents Dove Confident Me Indonesia: Single Session, a culturally adapted school-based intervention designed to improve Indonesian adolescents’ body image. It details the plan for evaluation, highlighting the strengths and limitations of the proposed study design. It will be informative for others aiming to adapt evidence-based school curricula to promote well-being among adolescents in LMICs. Trial registration: NCT04665557. Registered 11th December 2020. © 2021, The Author(s). |
Adolescent mental health; Body image; Indonesia; Life skills education; Low- and middle-income countries; Randomised controlled trial; School-based intervention; Single-session intervention; Southeast Asia; Study protocol |
adolescent; body image; human; Indonesia; pandemic; randomized controlled trial (topic); school; school health service; Adolescent; Body Image; COVID-19; Humans; Indonesia; Pandemics; Randomized Controlled Trials as Topic; SARS-CoV-2; School Health Services; Schools |
BioMed Central Ltd |
14712458 |
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34784916 |
Article |
Q1 |
1230 |
3166 |
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48 |
Wijaya I.P., Karim B., Azizi M.S., Ariyanto I., Mansjoer A., Yunihastuti E., Harimurti K., Alwi I., Lee S., Price P. |
57193731572;57192910797;57209578916;57193538110;24335647800;57221273925;23473513200;15055173800;56272877300;57201814264; |
Cytomegalovirus may influence vascular endothelial health in Indonesian HIV-infected patients after 5 years on ART |
2021 |
AIDS Research and Therapy |
18 |
1 |
83 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85119002384&doi=10.1186%2fs12981-021-00410-7&partnerID=40&md5=9b7b4701ffbdd4086f464a8411ac8de3 |
Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Virology and Cancer Pathobiology Research Centre, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; School of Medicine, Curtin University, Bentley, 6102, Australia |
Wijaya, I.P., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Karim, B., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Azizi, M.S., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Ariyanto, I., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Virology and Cancer Pathobiology Research Centre, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Mansjoer, A., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Yunihastuti, E., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Harimurti, K., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Alwi, I., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Lee, S., School of Medicine, Curtin University, Bentley, 6102, Australia; Price, P., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, School of Medicine, Curtin University, Bentley, 6102, Australia |
Objectives: Accelerated atherosclerosis in older HIV-infected patients has been attributed to persistent immune activation and high burden cytomegalovirus (CMV), as demonstrated in transplant recipients and the general population. Here we assess CMV and inflammatory markers linked with vascular health in young adult patients treated in Indonesia. Study design: HIV-infected adults (n = 32) were examined when they began antiretroviral therapy (ART) with < 200 CD4 T-cells/µl (V0) and after 60 months (V60). Age-matched healthy controls (HC, n = 32) were assessed once. Methods: Flow Mediated Dilatation (FMD) was assessed by ultrasound on brachial arteries at V60 and in HC. Plasma markers of immune activation and endothelial activation, and CMV antibodies (lysate, gB, IE-1) were assessed in all samples. Results were assessed using bivariate (non-parametric) and multivariable analyses. Results: Levels of inflammatory biomarkers and CMV antibodies declined on ART, but the antibodies remained higher than in HC. FMD values were similar in patients and HC at V60. In HIV patients, levels of CMV lysate antibody correlated inversely (r = − 0.37) with FMD. The optimal model predicting lower FMD values (adjusted R2 = 0.214, p = 0.012) included CMV lysate antibodies and chondroitin sulphate. In HC, levels of sTNFR correlated inversely with FMD (r = − 0.41) and remained as a risk factor in the optimal multivariable model, with CMV glycoprotein-B (gB) antibody predicting a healthier FMD (adjusted R2 = 0.248, p = 0.013). Conclusions: Higher levels CMV antibodies optimally predict vascular health measured by FMD in HIV patients. However in healthy controls, sTNFR marks risk and CMV gB antibody may be protective. © 2021, The Author(s). |
CMV; Endothelial function; HIV; Inflammatory biomarkers |
virus antibody; aged; Cytomegalovirus; cytomegalovirus infection; human; Human immunodeficiency virus infection; Indonesia; Aged; Antibodies, Viral; Cytomegalovirus; Cytomegalovirus Infections; HIV Infections; Humans; Indonesia |
BioMed Central Ltd |
17426405 |
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34763708 |
Article |
Q1 |
1102 |
3778 |
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49 |
Al-Jawadi A.A., Priliani L., Oktavianthi S., Febinia C.A., Daya M., Artika I.M., Malik S.G. |
57327931000;57203360168;38361976900;55195897900;57208032155;57194561825;7402973374; |
Association of FTO rs1421085 single nucleotide polymorphism with fat and fatty acid intake in Indonesian adults |
2021 |
BMC Research Notes |
14 |
1 |
411 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118749881&doi=10.1186%2fs13104-021-05823-1&partnerID=40&md5=c2e5f8f0c5b077d184062624f315d2dc |
Department of Biochemistry, Faculty of Mathematics and Natural Sciences, Bogor Agricultural University, Kampus IPB Dramaga, Jl. Raya Dramaga, Bogor, West Java 16680, Indonesia; Eijkman Institute for Molecular Biology, Ministry of Research and Technology/National Research and Innovation Agency, Jl. Diponegoro No. 69, Jakarta, 10430, Indonesia; Department of Nutrition, Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia |
Al-Jawadi, A.A., Department of Biochemistry, Faculty of Mathematics and Natural Sciences, Bogor Agricultural University, Kampus IPB Dramaga, Jl. Raya Dramaga, Bogor, West Java 16680, Indonesia; Priliani, L., Eijkman Institute for Molecular Biology, Ministry of Research and Technology/National Research and Innovation Agency, Jl. Diponegoro No. 69, Jakarta, 10430, Indonesia; Oktavianthi, S., Eijkman Institute for Molecular Biology, Ministry of Research and Technology/National Research and Innovation Agency, Jl. Diponegoro No. 69, Jakarta, 10430, Indonesia; Febinia, C.A., Eijkman Institute for Molecular Biology, Ministry of Research and Technology/National Research and Innovation Agency, Jl. Diponegoro No. 69, Jakarta, 10430, Indonesia; Daya, M., Department of Nutrition, Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Artika, I.M., Department of Biochemistry, Faculty of Mathematics and Natural Sciences, Bogor Agricultural University, Kampus IPB Dramaga, Jl. Raya Dramaga, Bogor, West Java 16680, Indonesia, Eijkman Institute for Molecular Biology, Ministry of Research and Technology/National Research and Innovation Agency, Jl. Diponegoro No. 69, Jakarta, 10430, Indonesia; Malik, S.G., Eijkman Institute for Molecular Biology, Ministry of Research and Technology/National Research and Innovation Agency, Jl. Diponegoro No. 69, Jakarta, 10430, Indonesia |
Objective: Recent studies showed that genetic polymorphisms in the fat mass and obesity-associated gene (FTO) were associated with obesity and dietary intake. In this study of 71 adults in Jakarta, Indonesia, we investigated FTO rs1421085 association with body mass index (BMI), macronutrient intake, and fatty acid intake. The association was evaluated using linear regression analyses assuming co-dominant, dominant, recessive, over-dominant, and additive genetic models. Results: Only individuals with the CC genotype had a considerably higher BMI (p < 0.001), which indicates a recessive genetic trait, but the incidence for this genotype is low (68 TT + TC vs. 3 CC). Individuals with the minor C allele had an estimated increase of fat intake by 3.45–4.06% across various genetic models (dominant: p < 0.010, over-dominant: p < 0.030, additive: p < 0.010). Subjects with TC/CC genotypes had increased dietary monounsaturated fatty acid (MUFA; 1.14%, p = 0.046) and saturated fatty acid (SAFA; 2.06%, p = 0.023) intakes, compared to those with the TT genotype. In conclusion, our study provided evidence for the association between FTO rs1421085 risk allele with higher BMI and individual preferences for consuming more fat, MUFA, and SAFA. This study highlights the important role of FTO gene in food preference, and its influence on body weight. © 2021, The Author(s). |
Fat intake; Fatty acid; FTO; Indonesia; Obesity; rs1421085 |
alpha ketoglutarate dependent dioxygenase FTO; fatty acid; FTO protein, human; adult; body mass; genetic predisposition; genetics; genotype; human; Indonesia; single nucleotide polymorphism; Adult; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Body Mass Index; Fatty Acids; Genetic Predisposition to Disease; Genotype; Humans; Indonesia; Polymorphism, Single Nucleotide |
BioMed Central Ltd |
17560500 |
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34743743 |
Article |
Q2 |
608 |
8303 |
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50 |
Sitorus R.S., Pambudy I.M., Rohsiswatmo R., Barliana J.D., Yulia D.E., Widyahening I.S. |
57221587271;57327482000;55533574600;57200964187;57225947931;54893154400; |
Retinal abnormalities in universal eye screening of healthy, full-term newborn infants in Jakarta. The incidence and its risk factors: a pilot study |
2021 |
International Journal of Retina and Vitreous |
7 |
1 |
67 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118713835&doi=10.1186%2fs40942-021-00337-1&partnerID=40&md5=e2db9f11d6ce04fd383ce64dbf98b9fa |
Department of Ophthalmology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo National Referral Hospital, Jalan Kimia No. 8-10, Jakarta, 10320, Indonesia; Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo National Referral Hospital, Jakarta, Indonesia; Department of Community Medicine, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Sitorus, R.S., Department of Ophthalmology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo National Referral Hospital, Jalan Kimia No. 8-10, Jakarta, 10320, Indonesia; Pambudy, I.M., Department of Ophthalmology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo National Referral Hospital, Jalan Kimia No. 8-10, Jakarta, 10320, Indonesia; Rohsiswatmo, R., Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo National Referral Hospital, Jakarta, Indonesia; Barliana, J.D., Department of Ophthalmology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo National Referral Hospital, Jalan Kimia No. 8-10, Jakarta, 10320, Indonesia; Yulia, D.E., Department of Ophthalmology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo National Referral Hospital, Jalan Kimia No. 8-10, Jakarta, 10320, Indonesia; Widyahening, I.S., Department of Community Medicine, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Aim: To screen for ocular abnormalities in healthy full-term newborn infants using wide-field digital imaging and to analyze factors associated with the findings. Methods: A total of 1208 full-term newborn infants at a tertiary eye hospital (Cipto Mangunkusumo National Referral Hospital) and a district hospital in Jakarta (Koja Hospital) were enrolled to the study. All eligible newborns underwent fundus examination within 48 h after birth using the RetCam shuttle (Natus Medical Incorporated, USA). Retinal findings were documented and analyzed according to obstetric and neonatal risk factors. Results: Of the 1208 newborn infants enrolled, ocular abnormalities were found in 150 infants (12.4%). Retinal hemorrhage (RH) was the most common finding (88%) in which 2.67% involved the macula, followed by chorioretinitis (4.67%). Univariate analysis showed caesarean section (C-section) (OR 0.27, 95% CI 0.18–0.41, p < 0.001) was a protective factor against RH, while prolonged labor increased the risk of developing RH (OR 1.84, 95% CI 1.24–2.72, p = 0.002). Further multivariate analysis showed similar protective association between C-section and risk of RH (OR 0.29, 95% CI 0.19–0.44, p < 0.001), while other risk factors were not. Conclusions: Our study showed that universal eye screening in healthy neonates is beneficial in the early diagnosis, monitoring and treatment of ocular abnormalities such as retinal hemorrhage, chorioretinitis and retinoblastoma. Retinal hemorrhage is the most common ocular abnormality and is associated with the delivery method and the duration of labor. Universal eye screening is visual-saving and life-saving for neonates with chorioretinitis, retinoblastoma as well as other abnormalities and should be mandatory in newborn screening. © 2021, The Author(s). |
Delivery; Healthy newborn; Hemorrhage; Universal eye screening |
antibiotic agent; local anesthetic agent; phenylephrine; tropicamide; Article; cesarean section; chorioretinitis; coloboma; controlled study; cross-sectional study; digital imaging; early diagnosis; eye examination; female; human; incidence; intraocular tumor; macular degeneration; major clinical study; male; newborn; newborn screening; optic nerve disease; patient referral; pediatric patient; pilot study; retina disease; retina hemorrhage; retina macula hemorrhage; retina macula lutea; retina maculopathy; retinoblastoma; risk factor; vitreous hemorrhage |
BioMed Central Ltd |
20569920 |
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Article |
Q1 |
1617 |
1984 |
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51 |
Viswanathan S., Hiew F.L., Siritho S., Apiwattanakul M., Tan K., Quek A.M.L., Estiasari R., Remli R., Bhaskar S., Islam B.M., Aye S.M.M., Ohnmar O., Umapathi T., Keosodsay S.S., Hoang N.T.T., Yeo T., Pasco P.M. |
56372225400;56520422700;15519966800;57195288799;37032197900;13605538000;55240204000;6504090091;57226417398;57194464797;55644071900;57201460031;6602092493;57201460833;57310352700;57310352800;6506559205; |
Impact of Covid-19 on the therapeutic plasma exchange service within the South East Asian region: Consensus recommendations and global perspectives |
2021 |
Journal of Clinical Apheresis |
36 |
6 |
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849 |
863 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117763064&doi=10.1002%2fjca.21937&partnerID=40&md5=3fb4e2326e829716a437226b18f33390 |
Department of Neurology, Kuala Lumpur Hospital, Kuala Lumpur, Malaysia; Department of Neurology, Bumrungrad International Hospital and Siriraj Hospital, Mahidol University, Bangkok, Thailand; Department of Neurology, Neurological Institute of Thailand, Bangkok, Thailand; Department of Neurology, National Neuroscience Institute, Singapore; Division of Neurology, Department of Medicine, National University Health System, Singapore; Department of Neurology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Neurology, National University of Malaysia, Kuala Lumpur, Malaysia; Department of Medicine, Universiti Teknologi MARA, Sg Buloh, Selangor, Malaysia; Department of Laboratory Sciences and Services Division, The International Center for Diarrhoeal Disease Research, Dhaka, Bangladesh; Department of Neurology, Aryu International Hospital, Yangon, Myanmar; Department of Neurology, Yangon General Hospital, Yangon, Myanmar; Department of Neurology, Laos General Hospital, Vientiane, Laos; Department of Neurology, Military Hospital 175, Ho Chi Minh City, Viet Nam; Department of Neurosciences, Philippine General Hospital, Manila, Philippines |
Viswanathan, S., Department of Neurology, Kuala Lumpur Hospital, Kuala Lumpur, Malaysia; Hiew, F.L., Department of Neurology, Kuala Lumpur Hospital, Kuala Lumpur, Malaysia; Siritho, S., Department of Neurology, Bumrungrad International Hospital and Siriraj Hospital, Mahidol University, Bangkok, Thailand; Apiwattanakul, M., Department of Neurology, Neurological Institute of Thailand, Bangkok, Thailand; Tan, K., Department of Neurology, National Neuroscience Institute, Singapore; Quek, A.M.L., Division of Neurology, Department of Medicine, National University Health System, Singapore; Estiasari, R., Department of Neurology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Remli, R., Department of Neurology, National University of Malaysia, Kuala Lumpur, Malaysia; Bhaskar, S., Department of Medicine, Universiti Teknologi MARA, Sg Buloh, Selangor, Malaysia; Islam, B.M., Department of Laboratory Sciences and Services Division, The International Center for Diarrhoeal Disease Research, Dhaka, Bangladesh; Aye, S.M.M., Department of Neurology, Aryu International Hospital, Yangon, Myanmar; Ohnmar, O., Department of Neurology, Yangon General Hospital, Yangon, Myanmar; Umapathi, T., Department of Neurology, National Neuroscience Institute, Singapore; Keosodsay, S.S., Department of Neurology, Laos General Hospital, Vientiane, Laos; Hoang, N.T.T., Department of Neurology, Military Hospital 175, Ho Chi Minh City, Viet Nam; Yeo, T., Department of Neurology, National Neuroscience Institute, Singapore; Pasco, P.M., Department of Neurosciences, Philippine General Hospital, Manila, Philippines |
Introduction: Therapeutic plasma exchange (TPE) for neuroimmunological disorders has played an increasingly important role within the Southeast Asian (SEA) region. The South East Asian Therapeutic Plasma exchange Consortium (SEATPEC) was formed in 2018 to promote education and research on TPE within the region. The advent of the Covid-19 pandemic has produced challenges for the development and expansion of this service. Methodology: A qualitative and semi-quantitative questionnaire-based survey was conducted by SEATPEC member countries from January to June 2020 (Phase 1) and then from July 2020 to January 2021 in (Phase 2) to assess the impact of Covid-19 on regional TPE. Objectives: The study's main objectives were to explore the challenges experienced and adaptations/adjustments taken by SEATPEC countries in order to continue safe and efficient TPE during the Covid-19 pandemic. Results: The pandemic was found to disrupt the delivery of TPE services in all SEATPEC countries. Contributing factors were multifactorial due to overstretched medical services, staff shortages, quarantines and redeployments, fear of acquiring Covid-19, movement restriction orders, and patient's psychological fear of attending hospitals/testing for Covid-19. All SEATPEC countries practiced careful stratification of cases for TPE (electives vs emergencies, Covid-19 vs non-Covid-19 cases). SEATPEC countries had to modify TPE treatment protocols to include careful preprocedure screening of patient's for Covid-19, use of personal protective equipment (PPE) and post-TPE sanitization of machines and TPE suites. Conclusion: Based on the responses of the survey, SEATPEC countries produced a consensus statement with five recommendations for safe and effective TPE within the region. © 2021 Wiley Periodicals LLC. |
Covid-19; impact; South East Asia; therapeutic plasma exchange |
complication; consensus; epidemiology; human; neurologic disease; neurologist; pandemic; plasma exchange; procedures; questionnaire; Southeast Asia; Asia, Southeastern; Consensus; COVID-19; Humans; Nervous System Diseases; Neurologists; Pandemics; Plasma Exchange; SARS-CoV-2; Surveys and Questionnaires |
John Wiley and Sons Inc |
07332459 |
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34694652 |
Article |
Q2 |
697 |
7146 |
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52 |
Nababan S.H.H., Mansjoer A., Fauzi A., Gani R.A. |
57205443199;24335647800;36518523000;23495930300; |
Predictive scoring systems for in-hospital mortality due to acutely decompensated liver cirrhosis in Indonesia |
2021 |
BMC Gastroenterology |
21 |
1 |
392 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117564939&doi=10.1186%2fs12876-021-01972-6&partnerID=40&md5=8028251c29a052e830e58ba7b4786ff1 |
Hepatobiliary Division, Internal Medicine Department, Cipto Mangunkusumo National General Hospital, Faculty of Medicine, Universitas Indonesia, Jl. Diponegoro No. 71, Jakarta, 10430, Indonesia; Clinical Epidemiology Unit, Internal Medicine Department, Cipto Mangunkusumo National General Hospital, Faculty of Medicine, Universitas Indonesia, Jl. Diponegoro No.71, Jakarta, 10430, Indonesia; Gastroenterology Division, Internal Medicine Department, Cipto Mangunkusumo National General Hospital, Faculty of Medicine, Universitas Indonesia, Jl. Diponegoro No.71, Jakarta, 10430, Indonesia |
Nababan, S.H.H., Hepatobiliary Division, Internal Medicine Department, Cipto Mangunkusumo National General Hospital, Faculty of Medicine, Universitas Indonesia, Jl. Diponegoro No. 71, Jakarta, 10430, Indonesia; Mansjoer, A., Clinical Epidemiology Unit, Internal Medicine Department, Cipto Mangunkusumo National General Hospital, Faculty of Medicine, Universitas Indonesia, Jl. Diponegoro No.71, Jakarta, 10430, Indonesia; Fauzi, A., Gastroenterology Division, Internal Medicine Department, Cipto Mangunkusumo National General Hospital, Faculty of Medicine, Universitas Indonesia, Jl. Diponegoro No.71, Jakarta, 10430, Indonesia; Gani, R.A., Hepatobiliary Division, Internal Medicine Department, Cipto Mangunkusumo National General Hospital, Faculty of Medicine, Universitas Indonesia, Jl. Diponegoro No. 71, Jakarta, 10430, Indonesia |
Background: Acutely decompensated liver cirrhosis is associated with high medical costs and negatively affects productivity and quality of life. Data on factors associated with in-hospital mortality due to acutely decompensated liver cirrhosis in Indonesia are scarce. This study aims to identify predictors of in-hospital mortality and develop predictive scoring systems for clinical application in acutely decompensated liver cirrhosis patients. Methods: This was a retrospective cohort study using a hospital database of acutely decompensated liver cirrhosis data at Cipto Mangunkusumo National General Hospital, Jakarta (2016–2019). Bivariate and multivariate logistic regression analyses were performed to identify the predictors of in-hospital mortality. Two scoring systems were developed based on the identified predictors. Results: A total of 241 patients were analysed; patients were predominantly male (74.3%), had hepatitis B (38.6%), and had Child–Pugh class B or C cirrhosis (40% and 38%, respectively). Gastrointestinal bleeding was observed in 171 patients (70.9%), and 29 patients (12.03%) died during hospitalization. The independent predictors of in-hospital mortality were age (adjusted OR: 1.09 [1.03–1.14]; p = 0.001), bacterial infection (adjusted OR: 6.25 [2.31–16.92]; p < 0.001), total bilirubin level (adjusted OR: 3.01 [1.85–4.89]; p < 0.001) and creatinine level (adjusted OR: 2.70 [1.20–6.05]; p = 0.016). The logistic and additive scoring systems, which were developed based on the identified predictors, had AUROC values of 0.899 and 0.868, respectively. Conclusion: The in-hospital mortality rate of acutely decompensated liver cirrhosis in Indonesia is high. We have developed two predictive scoring systems for in-hospital mortality in acutely decompensated liver cirrhosis patients. © 2021, The Author(s). |
Acute decompensation; In-hospital mortality; Liver cirrhosis; Prognosis; Scoring system |
epidemiology; hospital mortality; human; Indonesia; liver cirrhosis; male; prognosis; quality of life; retrospective study; Hospital Mortality; Humans; Indonesia; Liver Cirrhosis; Male; Prognosis; Quality of Life; Retrospective Studies |
BioMed Central Ltd |
1471230X |
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34670501 |
Article |
Q2 |
935 |
4832 |
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53 |
Goenarjo R., Dupuy O., Fraser S., Berryman N., Perrochon A., Bosquet L. |
57192916469;55250097700;56214500000;35602918000;55628941600;6602849323; |
Cardiorespiratory fitness and prefrontal cortex oxygenation during Stroop task in older males |
2021 |
Physiology and Behavior |
242 |
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113621 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117564635&doi=10.1016%2fj.physbeh.2021.113621&partnerID=40&md5=ac7c0401817c51ece69279b94bfe1755 |
Laboratoire MOVE (EA 6314), Faculté des Sciences du Sport, Université de Poitiers, Poitiers, France; Department of Medical Physiology, Faculty of Medicine, Universitas Indonesia, Depok, Indonesia; Interdisciplinary School of Health Sciences, Faculty of Health Sciences, University of Ottawa, Ottawa (Ontario), Canada; Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montréal, Canada; Laboratoire HAVAE (EA 6310), Université de Limoges, Limoges, France; Ecole de Kinésiologie et des Sciences de l'Activité Physique (EKSAP), Faculté de Médecine, Université de Montreal, Montreal, Canada; Département des Sciences de l'activité physique, Université du Québec à Montréal (UQAM), Montréal, Canada |
Goenarjo, R., Laboratoire MOVE (EA 6314), Faculté des Sciences du Sport, Université de Poitiers, Poitiers, France, Department of Medical Physiology, Faculty of Medicine, Universitas Indonesia, Depok, Indonesia; Dupuy, O., Laboratoire MOVE (EA 6314), Faculté des Sciences du Sport, Université de Poitiers, Poitiers, France, Ecole de Kinésiologie et des Sciences de l'Activité Physique (EKSAP), Faculté de Médecine, Université de Montreal, Montreal, Canada; Fraser, S., Interdisciplinary School of Health Sciences, Faculty of Health Sciences, University of Ottawa, Ottawa (Ontario), Canada; Berryman, N., Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montréal, Canada, Département des Sciences de l'activité physique, Université du Québec à Montréal (UQAM), Montréal, Canada; Perrochon, A., Laboratoire HAVAE (EA 6310), Université de Limoges, Limoges, France; Bosquet, L., Laboratoire MOVE (EA 6314), Faculté des Sciences du Sport, Université de Poitiers, Poitiers, France, Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montréal, Canada, Ecole de Kinésiologie et des Sciences de l'Activité Physique (EKSAP), Faculté de Médecine, Université de Montreal, Montreal, Canada |
Aim: The aim of the current study was to assess whether executive function and prefrontal oxygenation are dependent on fitness level and age in older adults. Methods: Twenty-four healthy males aged between 55 and 69 years old were recruited for this study. They were stratified by age, leading to the creation of two groups: 55–60 years old and 61–69 years old. A median split based on CRF created higher- and lower-fit categories of participants. Cerebral oxygenation was assessed using functional near-infrared spectroscopy (fNIRS) during a computerized Stroop task. Accuracy (% of correct responses) and reaction times (ms) were used as behavioural indicators of cognitive performances. Changes in oxygenated (∆[HbO2]) and deoxygenated (∆[HHb]) hemoglobin were measured to capture neural changes. Repeated measures ANOVAs (CRF × Age × Stroop conditions) were performed to test the null hypothesis of an absence of interaction between CRF, Age and executive performance. Results: We also found an interaction between CRF and age on reaction times (p = .001), in which higher fitness levels were related to faster reaction times in the 61–69 year olds but not in the 55–60 year olds. Regarding ΔHHb, the ANOVA revealed a main effect of CRF in the right PFC (p = .04), in which higher-fit participants had a greater Δ[HHb] than the lower-fit (d = 1.5). We also found fitness by age interaction for Δ[HHb] in the right PFC (p = .04). Conclusion: Our results support the positive association of CRF on cerebral oxygenation and Stroop performance in healthy older males. They indicated that high-fit individuals performed better in the 61–69 year olds group, but not in the 55–60 years old group. We also observed a greater PFC oxygenation change (as measured by Δ[HHb]) in the high-fit individuals. © 2021 |
Cardiorespiratory fitness; Cerebral oxygenation; Older adults; Prefrontal cortex; Stroop |
hemoglobin; oxyhemoglobin; adult; age; aged; Article; blood oxygenation; brain oxygen consumption; brain radiography; cardiorespiratory fitness; controlled study; deoxygenation; executive function; functional near-infrared spectroscopy; hemoglobin blood level; human; human experiment; male; measurement accuracy; normal human; peak oxygen uptake; prefrontal cortex; reaction time; Stroop test; executive function; metabolism; middle aged; prefrontal cortex; Stroop test; Aged; Cardiorespiratory Fitness; Executive Function; Humans; Male; Middle Aged; Oxyhemoglobins; Prefrontal Cortex; Stroop Test |
Elsevier Inc. |
00319384 |
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34648819 |
Article |
Q1 |
960 |
4644 |
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54 |
Harefa, Wijaya I.P., Muhadi, Rumende C.M., Nasution S.A., Koesnoe S., Marbun M.B., Shatri H. |
57298868100;57193731572;57189615533;14325966300;57189373134;26028015000;57195201827;28767986500; |
The association between 24-h blood pressure variability and major adverse cardiac events (MACE) in hospitalized patients with acute myocardial infarction: a retrospective cohort study |
2021 |
Egyptian Heart Journal |
73 |
1 |
88 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117340121&doi=10.1186%2fs43044-021-00213-1&partnerID=40&md5=c9f1acb17b55e567ab93cb770f13356a |
Department of Internal Medicine, Faculty of Medicine, University of Indonesia/Dr, CiptoMangunkusumo National Hospital Jakarta, Jakarta, Indonesia |
Harefa, Department of Internal Medicine, Faculty of Medicine, University of Indonesia/Dr, CiptoMangunkusumo National Hospital Jakarta, Jakarta, Indonesia; Wijaya, I.P., Department of Internal Medicine, Faculty of Medicine, University of Indonesia/Dr, CiptoMangunkusumo National Hospital Jakarta, Jakarta, Indonesia; Muhadi, Department of Internal Medicine, Faculty of Medicine, University of Indonesia/Dr, CiptoMangunkusumo National Hospital Jakarta, Jakarta, Indonesia; Rumende, C.M., Department of Internal Medicine, Faculty of Medicine, University of Indonesia/Dr, CiptoMangunkusumo National Hospital Jakarta, Jakarta, Indonesia; Nasution, S.A., Department of Internal Medicine, Faculty of Medicine, University of Indonesia/Dr, CiptoMangunkusumo National Hospital Jakarta, Jakarta, Indonesia; Koesnoe, S., Department of Internal Medicine, Faculty of Medicine, University of Indonesia/Dr, CiptoMangunkusumo National Hospital Jakarta, Jakarta, Indonesia; Marbun, M.B., Department of Internal Medicine, Faculty of Medicine, University of Indonesia/Dr, CiptoMangunkusumo National Hospital Jakarta, Jakarta, Indonesia; Shatri, H., Department of Internal Medicine, Faculty of Medicine, University of Indonesia/Dr, CiptoMangunkusumo National Hospital Jakarta, Jakarta, Indonesia |
Background: Acute myocardial infarction (AMI) is major cardiovascular disease that causes high morbidity and mortality. In AMI, ischemia and necrosis affected some cardiomyocytes leading to a decrease in myocardial contractility which is followed by an acute proinflammation reaction and increased sympathetic tone. Meanwhile, high blood pressure variability (BPV) causing an increased left ventricular workload, heart rate, myocardial oxygen demand and induces proinflamations and endothelial dysfunction. Therefore a high BPV and its associated pathological effects are likely to aggravate the physiological function of the heart and affect the emergence of acute cardiac complications in AMI patients. This study aims to investigate the association’s between short-term BPV and major adverse cardiac events (MACE) in AMI patients. This retrospective cohort study used simple random sampling to identify AMI patients who were hospitalized at Cipto Mangunkusumo National Hospital between January 2018 and December 2019. Mann Withney was performed to investigate the association between BPV and MACE. Results: The average systolic BPV value which was calculated as standard deviation (SD) and average real variability (ARV) was higher in the MACE group than in the non-MACE group. Systolic SD and systolic ARV in the MACE group were 13.28 ± 5.41 mmHg and 9.88 ± 3.81 mmHg respectively. In the non-MACE group, systolic SD and systolic ARV were 10.76 (4.59–26.17) mmHg and 8.65 (3.22–19.35) mmHg respectively. There was no significant association between BPV and MACE. However, there were significant differences between systolic SD and systolic ARV in patients with hypertension who experienced MACE and patients without hypertension who experienced MACE. Conclusions: The BPV of AMI patients who experience MACE was higher than that of non-MACE AMI patients. There was no significant association between BPV and MACE during the acute phase of AMI. © 2021, The Author(s). |
Acute myocardial infarction; Average real variability; Blood pressure variability; Major adverse cardiac events |
acute heart infarction; adult; aged; Article; blood pressure monitoring; blood pressure variability; cohort analysis; controlled study; diastolic blood pressure; female; heart function; hospital patient; human; hypertension; major adverse cardiac event; major clinical study; male; retrospective study; systolic blood pressure |
Springer Science and Business Media Deutschland GmbH |
11102608 |
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Article |
Q3 |
212 |
18617 |
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55 |
Mansyur M., Sagitasari R., Wangge G., Sulistomo A.B., Kekalih A. |
37085506800;57290722900;36497482500;57024018500;55633562200; |
Long working hours, poor sleep quality, and work-family conflict: determinant factors of fatigue among Indonesian tugboat crewmembers |
2021 |
BMC Public Health |
21 |
1 |
1832 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85116761265&doi=10.1186%2fs12889-021-11883-6&partnerID=40&md5=4563534bbfe5b850aae54955a11550c5 |
Occupational Medicine Division, Community Medicine Department, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; South East Asian Ministers Education Organization, Regional Center for Food and Nutrition/SEAMEO-RECFON, Pusat Kajian Gizi Regional Universitas Indonesia, Jakarta, Indonesia; Occupational Medicine Post Graduate Study Program, Community Medicine Department, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Mansyur, M., Occupational Medicine Division, Community Medicine Department, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, South East Asian Ministers Education Organization, Regional Center for Food and Nutrition/SEAMEO-RECFON, Pusat Kajian Gizi Regional Universitas Indonesia, Jakarta, Indonesia; Sagitasari, R., Occupational Medicine Post Graduate Study Program, Community Medicine Department, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Wangge, G., South East Asian Ministers Education Organization, Regional Center for Food and Nutrition/SEAMEO-RECFON, Pusat Kajian Gizi Regional Universitas Indonesia, Jakarta, Indonesia; Sulistomo, A.B., Occupational Medicine Division, Community Medicine Department, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Kekalih, A., Occupational Medicine Division, Community Medicine Department, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Background: Tugboat crewmembers are susceptible to fatigue during their 24-h work shifts, despite the availability of rest time. The fatigue experienced by seafarers contributes to marine accidents and metabolic and cardiovascular diseases, which have long-term effects. This study aimed to analyse the association between working hours and fatigue and other possibly related factors in tugboat crewmembers. Method: This comparative cross-sectional study included 127 tugboat crew members from 15 randomly chosen tugboats in Samarinda Harbor, Indonesia. Their fatigue levels while at work were measured using a reaction timer and standardised questionnaire. Personal and occupational data of crewmembers, including age, marital status, rating (job ranking), duration on board, length of seafaring experience, watch system, smoking status, coffee and alcohol consumption, and working hours, were collected. Moreover, sleep quality and stress levels related to work-family conflict were measured and analysed using the Pittsburgh Sleep Quality Index (PSQI) and Work-Family Conflict Scale (WCFS), respectively. Results: The study found that 40.2% of the subjects were classified as having fatigue. The determinant factors were long working hours (> 72 h/week), poor sleep quality, and work-family conflict [adj. OR = 13.32; 95%-CI (4.78–31.23)] and p < 0.001, [adj. OR = 4.49 (1.39–14.52)] and p = 0.012, [adj. OR = 2.87 (1.12–7.33)] and p = 0.028, respectively. However, personal and occupational factors, including age, marital status, duration on board, length of seafaring experience, smoking status, and coffee and alcohol consumption, were not significantly associated with crewmember fatigue. Conclusion: The incidence of fatigue among Indonesian tugboat crewmembers operating on the Mahakam River was considerably high. Working hours, sleep quality, and work-family conflict were strongly associated with fatigue in tugboat crewmembers; therefore, the working hours of tugboat crewmembers need to be improved. Crewmember lifestyle variables need to be studied further. © 2021, The Author(s). |
Fatigue; Seafarer; Sleep quality; Tugboat crewmembers; Work-family conflict; Working hours |
cross-sectional study; family conflict; fatigue; human; Indonesia; sleep; work schedule; Cross-Sectional Studies; Family Conflict; Fatigue; Humans; Indonesia; Sleep; Work Schedule Tolerance |
BioMed Central Ltd |
14712458 |
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34627227 |
Article |
Q1 |
1230 |
3166 |
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