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119 |
Parikesit D., Adityagama M., Atmoko W., Birowo P., Taher A., Rasyid N. |
57163830300;57328473300;57193125664;6504153311;7005269743;56245069300; |
Reliability and validity of the Indonesian version of the aging males’ symptoms |
2021 |
Medical Journal of Indonesia |
30 |
3 |
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211 |
214 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118800087&doi=10.13181%2fmji.oa.215314&partnerID=40&md5=de2f7f19ff7768cc59e6ab7817803329 |
Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Urology, Faculty of Medicine, Universitas Indonesia, Universitas Indonesia Hospital, Depok, Indonesia |
Parikesit, D., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia, Department of Urology, Faculty of Medicine, Universitas Indonesia, Universitas Indonesia Hospital, Depok, Indonesia; Adityagama, M., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Atmoko, W., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia, Department of Urology, Faculty of Medicine, Universitas Indonesia, Universitas Indonesia Hospital, Depok, Indonesia; Birowo, P., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Taher, A., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rasyid, N., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
BACKGROUND Aging males’ symptoms (AMS) scale was developed to study the problems of aging males, especially related to the quality of life. Currently, there is no valid and reliable Indonesian version of the AMS scale. This study was aimed to translate and evaluate the validity and reliability of the Indonesian version of the AMS scale. METHODS This cross-sectional study translated the existing AMS scale into Indonesian, which was tested in 40 years old males from May to August 2020. Cross-cultural validation of the AMS scale was conducted by translating the questionnaire from English to Indonesian by two independent-certified translators. The validity of the Indonesian version of the AMS scale was measured by conducting a Pearson correlation (r) analysis. The reliability of this questionnaire was tested and retested in 118 participants with a 2-week interval. In addition, Cronbach’s alpha value was measured and used as a reference. The first test was conducted in a corporate blood donor event in Matraman, East Jakarta, and the retest was conducted in Cipto Mangunkusumo Hospital. RESULTS The Indonesian version of the AMS scale was valid and had a good internal consistency with a Cronbach’s alpha value of 0.74. The test-retest reliability showed good reliability with an r-value of 0.981. Pearson correlation test showed that all questions in the questionnaire were valid (p<0.05) and correlated positively. CONCLUSIONS The Indonesian version of the AMS scale derived from this study is valid and has good reliability. © 2021, Faculty of Medicine, Universitas Indonesia. All rights reserved. |
Aging males’ symptoms scale; Indonesian; Reliability and validity |
adult; aging; article; blood donor; Cronbach alpha coefficient; cross-sectional study; human; human experiment; internal consistency; language; major clinical study; male; questionnaire; test retest reliability; validity |
Faculty of Medicine, Universitas Indonesia |
08531773 |
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Article |
Q4 |
164 |
21905 |
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120 |
Soedarman S., Rahardjo H.E. |
57220581938;37762030000; |
Potential predictors of detrusor underactivity in a urology outpatient clinic: A 5-year single center experience study |
2021 |
Medical Journal of Indonesia |
30 |
3 |
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207 |
210 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118768336&doi=10.13181%2fmji.oa.215102&partnerID=40&md5=8286bb60fbc23a9907af0545c3ad23c0 |
Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Soedarman, S., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rahardjo, H.E., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
BACKGROUND Detrusor underactivity (DU) is diagnosed using urodynamics, which caused by a combination of strength and duration of the bladder muscle and resulted in prolonged bladder emptying. Invasive urodynamics, which are limited in many clinical settings, should be performed efficiently in high-risk patients to reduce the risk of emerging complications during and after the procedure. Therefore, this study was aimed to identify the potential predictors of DU for limited clinical settings. METHODS This retrospective study was retrieved from the medical records of patients who underwent urodynamics in the Department of Urology, Cipto Mangunkusumo Hospital from 2015 to 2020. Age, sex, bladder capacity, bladder compliance, bladder outlet obstruction, history of stroke, diabetes mellitus (DM) status, and neurological abnormalities were analyzed using chi-square and Mann–Whitney to examine the potential predictors of DU. The odds ratio (OR) of each factor was also calculated. Logistic regression was furtherly used for the analysis. RESULTS A total of 649 patients were included in this study. Male (OR = 1.74, 95% CI = 1.28–2.38) and DM patients (OR = 2.06, 95% CI = 1.36–3.11) had a higher risk of DU, while bladder outlet obstruction (OR = 0.54, 95% CI = 0.39–0.76) was the protective factor of DU. Furthermore, multivariate analysis showed that the potential predictors of DU were male (OR = 1.903, 95% CI = 1.37–2.64), DM (OR= 1.899, 95% CI = 1.22–2.95), and bladder outlet obstruction (OR = 0.32, 95% CI = 0.32–0.65). CONCLUSIONS Age, sex, bladder outlet obstruction, and history of DM could become the predictors of DU. © 2021, Faculty of Medicine, Universitas Indonesia. All rights reserved. |
Detrusor underactivity; Urinary bladder; Urodynamics |
adolescent; adult; age; aged; Article; bladder capacity; bladder compliance; bladder pressure; child; diabetes mellitus; diabetic patient; human; hypotonic bladder; major clinical study; male; neurologic disease; overactive bladder; sex; software; urodynamics |
Faculty of Medicine, Universitas Indonesia |
08531773 |
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Article |
Q4 |
164 |
21905 |
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121 |
Sutojo B., Irdam G.A. |
57218247988;57194729795; |
Safety of augmentation cystoplasty in patients with bladder abnormalities undergoing renal transplantation: A systematic review |
2021 |
Medical Journal of Indonesia |
30 |
3 |
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198 |
206 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118766468&doi=10.13181%2fmji.oa.204358&partnerID=40&md5=c0ca75b4e475d11f04014befaa03201a |
Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Sutojo, B., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Irdam, G.A., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
BACKGROUND Augmentation cystoplasty (AC) has been recently proposed to improve a bladder condition before or after a renal transplantation for an optimal allograft function. Until now, AC in adults with end-stage renal disease (ESRD) is uncommon and rarely practiced. This study aimed to investigate the safety of AC in patients with bladder abnormalities who required renal transplantation. METHODS Studies of patients with ESRD and abnormal bladder who underwent AC were searched in ProQuest, PubMed, EBSCO, and Cochrane Library online databases. Only studies published in English from January 1985 to May 2020 were included. The keywords used were renal transplantation, bladder dysfunction, cystoplasty, and their synonyms. Data were extracted by two independent authors who selected, screened, and assessed the articles’ eligibility and quality. The outcomes were graft survival rate and complications of AC. RESULTS A total of 19 articles were included. AC improved an intravesical pressure, a bladder capacity, and a compliance in patients with ESRD and bladder abnormalities, allowing patients to undergo the renal transplantation. Even though AC in patients with renal transplantation resulted in a significantly higher urinary tract infection rate than patients who underwent renal transplantation only, performing AC after renal transplantation was considered safe. CONCLUSIONS AC was considered safe for patients with bladder abnormalities who underwent renal transplantation. © 2021, Faculty of Medicine, Universitas Indonesia. All rights reserved. |
Cystoplasty; Efficacy; Renal transplantation; Safety |
Article; bladder pressure; bladder reconstruction; bladder rupture; colonoscopy; graft survival; kidney transplantation; nephrolithiasis; nonhuman; systematic review; ureter obstruction; urinary tract infection; urodynamics; urolithiasis; vesicoureteral reflux; wound healing |
Faculty of Medicine, Universitas Indonesia |
08531773 |
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Article |
Q4 |
164 |
21905 |
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123 |
Hapsari P.W., Februhartanty J., Bardosono S. |
57211782261;54962283200;21933841000; |
Students’ interests and learning venues as enablers for school-based nutrition education among adolescents in Jakarta |
2021 |
Nutrition and Food Science |
51 |
8 |
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1245 |
1257 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85107899113&doi=10.1108%2fNFS-12-2020-0475&partnerID=40&md5=b45b1711d6c37301cd7a37b8fbd2c4c5 |
Department of Nutrition, Faculty of Medicine, Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Southeast Asian Ministers of Education Organization Regional Centre for Food and Nutrition (SEAMEO RECFON)/Pusat Kajian Gizi Regional Universitas Indonesia, Jakarta, Indonesia; Department of Nutrition, Faculty of Medicine, Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Southeast Asian Ministers of Education Organization Regional Centre for Food and Nutrition (SEAMEO RECFON), Pusat Kajian Gizi Regional Universitas Indonesia, Department of Nutrition Science, Universitas Jenderal Soedirman, Jakarta, Purwokerto, Indonesia |
Hapsari, P.W., Department of Nutrition, Faculty of Medicine, Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia, Southeast Asian Ministers of Education Organization Regional Centre for Food and Nutrition (SEAMEO RECFON), Pusat Kajian Gizi Regional Universitas Indonesia, Department of Nutrition Science, Universitas Jenderal Soedirman, Jakarta, Purwokerto, Indonesia; Februhartanty, J., Southeast Asian Ministers of Education Organization Regional Centre for Food and Nutrition (SEAMEO RECFON)/Pusat Kajian Gizi Regional Universitas Indonesia, Jakarta, Indonesia; Bardosono, S., Department of Nutrition, Faculty of Medicine, Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Purpose: This study aims to explore potential enablers for school-based nutrition education (SBNE) through adolescent students’ perceptions in Jakarta, Indonesia. Design/methodology/approach: The study conducted 15 focus group discussions (FGDs) with 6–8 students per group to gather the main data, supported by six in-depth interviews with junior high school officials and content analysis of selected schoolbooks among five schools. The FGDs were conducted to explore students’ interest in nutrition information and their exposure to nutrition education and learning experiences. To analyze the FGD responses, three steps were used: coding, categorizing and determining themes. Findings: Students’ interest in nutrition and potential learning venues for interactive nutrition education were potential enablers for SBNE. The students’ interest in nutrition information comprised eight topics, with some different patterns by gender. Nutrition information not represented in the school books included: food fads, women’s nutrition, halal-certified food establishments and cooking. To complement the nutrition information that was not provided in school books, student club activities and school special programs were suitable settings as potential learning venues for SBNE. Originality/value: This study is the first study exploring SBNE facilitators from students’ perspectives among adolescents in Jakarta. © 2021, Emerald Publishing Limited. |
Adolescents; Indonesia; Nutrition education |
adolescent; article; clinical article; content analysis; cooking; female; food fads; gender; human; human experiment; Indonesia; interview; learning; male; middle school; nutrition education; perception |
Emerald Group Holdings Ltd. |
00346659 |
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Article |
Q3 |
318 |
14272 |
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124 |
Bartlett A.W., Sudjaritruk T., Mohamed T.J., Anugulruengkit S., Kumarasamy N., Phongsamart W., Ly P.S., Truong K.H., Van Nguyen L., Do V.C., Ounchanum P., Puthanakit T., Chokephaibulkit K., Lumbiganon P., Kurniati N., Nik Yusoff N.K., Wati D.K., Sohn A.H., Kariminia A. |
56511395900;36538198800;46961185600;57209773680;7003549856;8885235300;9743902800;35811540200;54396225800;56732729400;57200558813;8071686900;7003974471;35564244800;36473260300;6504631866;55816676300;7006405275;6602745222; |
Identification, Management, and Outcomes of Combination Antiretroviral Treatment Failure in Adolescents With Perinatal Human Immunodeficiency Virus Infection in Asia |
2021 |
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America |
73 |
7 |
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e1919 |
e1926 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118283335&doi=10.1093%2fcid%2fciaa872&partnerID=40&md5=7af8cf47bd95718a30d3277b5797f9ba |
Kirby Institute, University of New South Wales, Sydney, Australia; Department of Pediatrics, Faculty of Medicine, Research Institute for Health Sciences, Chiang Mai UniversityChiang Mai, Thailand; Women and Children Hospital Kuala LumpurKuala Lumpur, Malaysia; Department of Pediatrics, Faculty of Medicine, Chulalongkorn UniversityBangkok, Thailand; Center of Excellence for Pediatric Infectious Diseases and Vaccines, Faculty of Medicine, Chulalongkorn UniversityBangkok, Thailand; Chennai Antiviral Research and Treatment Clinical Research Site, VHS-Infectious Diseases Medical Centre, Voluntary Health Services, Chennai, India; Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol UniversityBangkok, Thailand; National Centre for HIV/AIDS, Dermatology and Sexually Transmitted DiseasesPhnom Penh, Cambodia; Children's Hospital 1, Ho Chi Minh City, Viet Nam; National Hospital of PediatricsHanoi, Viet Nam; Children's Hospital 2, Ho Chi Minh City, Viet Nam; Chiangrai Prachanukroh HospitalChiang Rai, Thailand; Department of Pediatrics, Faculty of Medicine, Khon Kaen UniversityKhon Kaen, Thailand; Cipto Mangunkusumo-Faculty of Medicine Universitas IndonesiaJakarta, Indonesia; Hospital Raja Perempuan Zainab IIKelantan, Malaysia; Sanglah Hospital, Udayana UniversityBali, Indonesia; TREAT Asia, amfAR-the Foundation for AIDS ResearchBangkok, Thailand |
Bartlett, A.W., Kirby Institute, University of New South Wales, Sydney, Australia; Sudjaritruk, T., Department of Pediatrics, Faculty of Medicine, Research Institute for Health Sciences, Chiang Mai UniversityChiang Mai, Thailand; Mohamed, T.J., Women and Children Hospital Kuala LumpurKuala Lumpur, Malaysia; Anugulruengkit, S., Department of Pediatrics, Faculty of Medicine, Chulalongkorn UniversityBangkok, Thailand, Center of Excellence for Pediatric Infectious Diseases and Vaccines, Faculty of Medicine, Chulalongkorn UniversityBangkok, Thailand; Kumarasamy, N., Chennai Antiviral Research and Treatment Clinical Research Site, VHS-Infectious Diseases Medical Centre, Voluntary Health Services, Chennai, India; Phongsamart, W., Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol UniversityBangkok, Thailand; Ly, P.S., National Centre for HIV/AIDS, Dermatology and Sexually Transmitted DiseasesPhnom Penh, Cambodia; Truong, K.H., Children's Hospital 1, Ho Chi Minh City, Viet Nam; Van Nguyen, L., National Hospital of PediatricsHanoi, Viet Nam; Do, V.C., Children's Hospital 2, Ho Chi Minh City, Viet Nam; Ounchanum, P., Chiangrai Prachanukroh HospitalChiang Rai, Thailand; Puthanakit, T., Department of Pediatrics, Faculty of Medicine, Chulalongkorn UniversityBangkok, Thailand, Center of Excellence for Pediatric Infectious Diseases and Vaccines, Faculty of Medicine, Chulalongkorn UniversityBangkok, Thailand; Chokephaibulkit, K., Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol UniversityBangkok, Thailand; Lumbiganon, P., Department of Pediatrics, Faculty of Medicine, Khon Kaen UniversityKhon Kaen, Thailand; Kurniati, N., Cipto Mangunkusumo-Faculty of Medicine Universitas IndonesiaJakarta, Indonesia; Nik Yusoff, N.K., Hospital Raja Perempuan Zainab IIKelantan, Malaysia; Wati, D.K., Sanglah Hospital, Udayana UniversityBali, Indonesia; Sohn, A.H., TREAT Asia, amfAR-the Foundation for AIDS ResearchBangkok, Thailand; Kariminia, A., Kirby Institute, University of New South Wales, Sydney, Australia |
BACKGROUND: Combination antiretroviral therapy (cART) failure is a major threat to human immunodeficiency virus (HIV) programs, with implications for individual- and population-level outcomes. Adolescents with perinatally acquired HIV infection (PHIVA) should be a focus for treatment failure given their poorer outcomes compared to children and adults. METHODS: Data (2014-2018) from a regional cohort of Asian PHIVA who received at least 6 months of continuous cART were analyzed. Treatment failure was defined according to World Health Organization criteria. Descriptive analyses were used to report treatment failure and subsequent management and evaluate postfailure CD4 count and viral load trends. Kaplan-Meier survival analyses were used to compare the cumulative incidence of death and loss to follow-up (LTFU) by treatment failure status. RESULTS: A total 3196 PHIVA were included in the analysis with a median follow-up period of 3.0 years, of whom 230 (7.2%) had experienced 292 treatment failure events (161 virologic, 128 immunologic, 11 clinical) at a rate of 3.78 per 100 person-years. Of the 292 treatment failure events, 31 (10.6%) had a subsequent cART switch within 6 months, which resulted in better immunologic and virologic outcomes compared to those who did not switch cART. The 5-year cumulative incidence of death and LTFU following treatment failure was 18.5% compared to 10.1% without treatment failure. CONCLUSIONS: Improved implementation of virologic monitoring is required to realize the benefits of virologic determination of cART failure. There is a need to address issues related to accessibility to subsequent cART regimens, poor adherence limiting scope to switch regimens, and the role of antiretroviral resistance testing. © The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com. |
adolescent; antiretroviral therapy; HIV; treatment failure |
anti human immunodeficiency virus agent; adolescent; adult; Asia; CD4 lymphocyte count; child; female; human; Human immunodeficiency virus infection; pregnancy; treatment failure; virus load; Adolescent; Adult; Anti-HIV Agents; Asia; CD4 Lymphocyte Count; Child; Female; HIV Infections; Humans; Pregnancy; Treatment Failure; Viral Load |
NLM (Medline) |
15376591 |
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32589711 |
Article |
Q1 |
3440 |
518 |
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125 |
Hermansyah T.A., Ginanjar E., Putri V.H. |
57428569000;23472616600;57428569100; |
Elevation of Cardiac Biomarkers in COVID-19 As a Major Determinant for Mortality: A Systematic Review |
2021 |
Acta medica Indonesiana |
53 |
4 |
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385 |
396 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85123568570&partnerID=40&md5=0047595d5dd32380033c242e7c79fe4c |
Faculty of Medicine Universitas IndonesiaJakarta, Indonesia |
Hermansyah, T.A., Faculty of Medicine Universitas IndonesiaJakarta, Indonesia; Ginanjar, E.; Putri, V.H. |
BACKGROUND: This study aimed to summarize the prognosis of Corona Virus Disease 2019 (COVID-19) patients with elevated troponin and N-terminal pro brain natriuretic peptide (NT-proBNP) levels and demonstrate the involvement of myocardial injury as a complication in COVID-19. METHODS: A systematic literature search was performed using several databases (PubMed, MEDLINE, PROQUEST and SCOPUS ) for studies published up to August 2020. Observational studies about the mortality outcome of COVID-19 patients who experienced cardiac injury, as defined by the elevation of serum levels of troponin, brain natriuretic peptide (BNP), with NT-proBNP or only BNP or only NT-proBNP, were included. In addition, a critical appraisal was conducted for all included studies using the Critical Appraisal for Prognostic Studies checklist published by the Centre for Evidence-Based Medicine by the University of Oxford. RESULTS: Seven retrospective observational studies fulfilled the inclusion criteria. This study found that there is a higher risk of death in COVID 19 patients with higher levels of troponin and NT-proBNP, indicating the importance of these biomarkers as determinant factors to predict in-hospital deaths. CONCLUSION: Based on the analysis, elevation of troponin and NT-proBNP levels plays an essential role in determining the patient prognosis because it is shown to be associated with in-hospital mortality. This also supports the involvement of myocardial injury as a prominent fatal complication in COVID-19. |
BNP; COVID-19; myocardial injury; NT-proBNP; prognostic factors; troponin |
biological marker; brain natriuretic peptide; peptide fragment; pro-brain natriuretic peptide (1-76); troponin; blood; human; mortality; observational study; prognosis; retrospective study; Biomarkers; COVID-19; Humans; Natriuretic Peptide, Brain; Observational Studies as Topic; Peptide Fragments; Prognosis; Retrospective Studies; SARS-CoV-2; Troponin |
NLM (Medline) |
01259326 |
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35027485 |
Article |
Q3 |
321 |
14162 |
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126 |
Saldi S.R.F., Safitri E.D., Setiati S., Ranakusuma R.W., Marsigit J., Azwar M.K., Astuti P., Sari C.Y.I., Istanti R., Yulianti M., Rumende C.M., Yunihastuti E., Susilo A., Harimurti K., Liastuti L.D., Trimartani T., Restuti R.D., Syam A.F. |
55201904000;57195934356;14325991900;57189729404;57218912589;57202798959;57436688300;57218292263;23496653300;57216405885;14325966300;57221273925;57217867079;23473513200;57204676441;57428529000;55261428300;8443384400; |
Prognostic Scoring System for Mortality of Hospitalized COVID-19 Patients in Resource-Limited Settings: A Multicenter Study from COVID-19 Referral Hospitals |
2021 |
Acta medica Indonesiana |
53 |
4 |
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407 |
415 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85123568238&partnerID=40&md5=e5654832599ee37e6d1d6dad0e5cc30c |
Clinical Epidemiology and Evidence-Based Medicine, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo HospitalJakarta, Indonesia |
Saldi, S.R.F., Clinical Epidemiology and Evidence-Based Medicine, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo HospitalJakarta, Indonesia; Safitri, E.D.; Setiati, S.; Ranakusuma, R.W.; Marsigit, J.; Azwar, M.K.; Astuti, P.; Sari, C.Y.I.; Istanti, R.; Yulianti, M.; Rumende, C.M.; Yunihastuti, E.; Susilo, A.; Harimurti, K.; Liastuti, L.D.; Trimartani, T.; Restuti, R.D.; Syam, A.F. |
BACKGROUND: Many studies identified the risk factors and prognostic factors related to in-hospital COVID-19 mortality using sophisticated laboratory tests. Cost and the availability of supporting blood tests may be problematic in resource-limited settings. This multicenter cohort study was conducted to assess the factors associated with mortality of COVID-19 patients aged 18 years and older, based on history taking, physical examination, and simple blood tests to be used in resource-limited settings. METHODS: The study was conducted between July 2020 and January 2021 in five COVID-19 referral hospitals in Indonesia. Among 1048 confirmed cases of COVID-19, 160 (15%) died during hospitalization. RESULTS: Multivariate analysis showed eight predictors of in-hospital mortality, namely increased age, chronic kidney disease, chronic obstructive pulmonary disease, fatigue, dyspnea, altered mental status, neutrophil-lymphocyte ratio (NLR) ≥ 5.8, and severe-critical condition. This scoring system had an Area-under-the-curve (AUC) of 84.7%. With cut-off score of 6, the sensitivity was 76.3% and the specificity was 78.2%. CONCLUSION: The result of this practical prognostic scoring system may be a guide to decision making of physicians and help in the education of family members related to the possible outcome. |
COVID-19; mortality; predictive score; prognostic; resource-limited settings |
clinical trial; comorbidity; health care planning; hospital; hospital mortality; human; mortality; multicenter study; patient referral; prognosis; retrospective study; sensitivity and specificity; Comorbidity; COVID-19; Health Resources; Hospital Mortality; Hospitals; Humans; Prognosis; Referral and Consultation; Retrospective Studies; SARS-CoV-2; Sensitivity and Specificity |
NLM (Medline) |
01259326 |
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35027487 |
Article |
Q3 |
321 |
14162 |
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127 |
Yunihastuti E. |
57221273925; |
Prioritizing Health Care Workers Safety: The International Year of Health and Care Workers 2021 |
2021 |
Acta medica Indonesiana |
53 |
4 |
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371 |
373 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85123567858&partnerID=40&md5=6b031d0156ba2c68eb828650dd45d00d |
Division of Allergy and Clinical Immunology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo HospitalJakarta, Indonesia |
Yunihastuti, E., Division of Allergy and Clinical Immunology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo HospitalJakarta, Indonesia |
Healthcare workers pose a substantial risk of acquiring COVID-19 infection during their daily works. We have seen various conditions during the pandemic, such as limited adequate personal protective equipment (PPE), accurate diagnostic tests, lack of information regarding disease management, unsupportive work environment, and excessive workload, increased the number of HCWs-infected COVID-19. Compared to the general population, the risk of COVID-19 infection was several-fold higher in HCWs.Employers and health care workers both should share the responsibility to prevent occupationally acquired infections and avoid causing harm to patients by taking reasonable precautions to prevent vaccine-preventable disease transmission.This year, WHO has launched a year-long campaign under the theme -protect, invest, together'. It highlights the urgent need to invest in health care workers, not only during COVID-19. We need to ensure that all health care workers are supported, protected, motivated, and equipped to deliver safe health care at all times, to provide a high-quality standard of care to the patients. |
COVID-19; healthcare workers; personal protective equipment; safety; vaccination |
health care personnel; human; occupational health; pandemic; protective equipment; World Health Organization; COVID-19; Health Personnel; Humans; Occupational Health; Pandemics; Personal Protective Equipment; World Health Organization |
NLM (Medline) |
01259326 |
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35027483 |
Article |
Q3 |
321 |
14162 |
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128 |
Fadrian F., Chen K., Kumalawati J., Rumende C.M., Shatri H., Nelwan E.J. |
57268114000;57428620500;6504406695;14325966300;28767986500;14527452900; |
The Validation of Drug Resistance in Pneumonia (DRIP) Score in Predicting Infections due to Drug-Resistant Pathogens in Community-acquired Pneumonia at Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
2021 |
Acta medica Indonesiana |
53 |
4 |
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416 |
422 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85123567110&partnerID=40&md5=9488cfa84614808f64df6510f7925f6d |
1. Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Indonesia. 2. Division of Tropical Medicine and Infectious Disease, Department of Internal Medicine, Faculty of Medicine, alas University - M. Djamil Hospital, Padang, Jakarta, Indonesia |
Fadrian, F., 1. Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Indonesia. 2. Division of Tropical Medicine and Infectious Disease, Department of Internal Medicine, Faculty of Medicine, alas University - M. Djamil Hospital, Padang, Jakarta, Indonesia; Chen, K.; Kumalawati, J.; Rumende, C.M.; Shatri, H.; Nelwan, E.J. |
BACKGROUND: The emergence of drug-resistant pathogens (DRP) in recent years possibly contributes to the common problems associated with community-acquired pneumonia. However, to predict the risk of the ailment, the DRIP score is mainly applied, although no validation study has been reported in Indonesia. Therefore, the score prediction accuracy in the population, patient characteristics and germ patterns appears indefinite, particularly for Cipto Mangunkusumo Hospital, Jakarta. The purpose of this study is to determine the DRIP performance as an instrument in predicting infections due to drug-resistant pathogens (DRP) in community-acquired pneumonia at Cipto Mangunkusumo Hospital. METHODS: This research employed a cross-sectional design, where the subjects were community-acquired pneumonia patients treated between January 2019 and June 2020. In addition, adequate medical records of the participants were obtained. The condition is defined as DRP when the sputum culture results show resistance to non-pseudomonal β-lactam antibiotics, macrolides, and respiratory fluoroquinolones. Furthermore, the score performance was analyzed by determining the calibration and discrimination values, using the Hosmer-Lemeshow test and AUROC, respectively. RESULTS: A total of 254 subjects were known to have satisfied the selection criteria. These participants were categorized into DRP and non-DRP groups, with 103 (40.6%) and 151 (59.4%) patients, correspondingly. The DRIP calibration analysis using the Hosmer-Lemeshow test obtained p-value = 0.001 (p <0.05), while an AUC value of 0.759 (CI 95%, 0.702-0.810) was derived from the ROC curve. However, at a score of ≥ 4, the DRIP showed sensitivity, specificity, positive and negative predictive values of 70.9, 92.7, 86.9, and 82.3%, respectively. CONCLUSION: The DRIP score demonstrated a significant performance in predicting infections due to DRP in community-acquired pneumonia. |
community-acquired pneumonia; DRIP score; resistant pathogens |
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NLM (Medline) |
01259326 |
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35027488 |
Article |
Q3 |
321 |
14162 |
|
|
|
129 |
Nelwan E.J., Guterres H., Pasaribu A.I., Shakinah S., Limato R., Widodo D. |
14527452900;57223285438;57428543800;57428569400;57196224631;8231822900; |
The Comparison of Point Prevalence Survey (PPS) and Gyssens Flowchart Approach on Antimicrobial Use Surveillance in Indonesian National Referral Hospital |
2021 |
Acta medica Indonesiana |
53 |
4 |
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505 |
511 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85123566730&partnerID=40&md5=0eb0821dbbca8a19666af97b0fdd062d |
1. Division of Tropical and Infectious Disease, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Indonesia 2. Infection and Immunology Research Cluster, Indonesian Medical Research Institute Faculty of Medicine Universitas Indonesia, Indonesia 3. Member of Antimicrobial Resistance Control Cipto Mangunkusumo HospitalJakarta, Indonesia |
Nelwan, E.J., 1. Division of Tropical and Infectious Disease, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Indonesia 2. Infection and Immunology Research Cluster, Indonesian Medical Research Institute Faculty of Medicine Universitas Indonesia, Indonesia 3. Member of Antimicrobial Resistance Control Cipto Mangunkusumo HospitalJakarta, Indonesia; Guterres, H.; Pasaribu, A.I.; Shakinah, S.; Limato, R.; Widodo, D. |
The antimicrobial resistance (AMR) rate in Indonesia is steadily rising, despite the existing national action plan in 2014. In line with the Global Action Plan on AMR, proper surveillance on antimicrobial usage and resistance are needed. At present, antimicrobial surveillance (AMS) data in Indonesia is heterogeneous, fragmented, and localized. The common method of antimicrobial surveillance (AMS) in referral hospitals is by implementing Gyssens flowchart during Antimicrobial Resistance Control Program Committee clinical rounds. However, the recent method of AMS with Point Prevalence Survey (PPS) offers many advantages include its concise and simple protocol, large data collection, shorter required time, comprehensive data outcomes, real-time data, and standardized parameters. In low-middle income countries such as Indonesia with its restricted resources in AMS, PPS is superior compared to the 'traditional' hospital clinical round in generating representative and homogenous outcomes that can be compared to data from other centers worldwide. |
antimicrobial; Gyssens Flowchart; Indonesia; Point Prevalence Survey |
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NLM (Medline) |
01259326 |
|
35027501 |
Article |
Q3 |
321 |
14162 |
|
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