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184 |
Octaviana F., Harisman J., Wiratman W., Budikayanti A. |
26029958700;57368215900;57191920526;57194713932; |
Altered mental status in moderate-severe traumatic brain injury in Indonesia: the clinical manifestation and EEG features of non-convulsive status epilepticus |
2021 |
Heliyon |
7 |
9 |
e08067 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85120866388&doi=10.1016%2fj.heliyon.2021.e08067&partnerID=40&md5=87d284823bcddaa9acf0b35b27598f23 |
Neurology Department, Faculty of Medicine, Universitas Indonesia, Indonesia; Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia |
Octaviana, F., Neurology Department, Faculty of Medicine, Universitas Indonesia, Indonesia, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Harisman, J., Neurology Department, Faculty of Medicine, Universitas Indonesia, Indonesia; Wiratman, W., Neurology Department, Faculty of Medicine, Universitas Indonesia, Indonesia, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Budikayanti, A., Neurology Department, Faculty of Medicine, Universitas Indonesia, Indonesia, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia |
Introduction: Moderate-to-severe traumatic brain injury (msTBI) can cause non-convulsive status epilepticus (NCSE). Electroencephalography (EEG) is employed as a diagnostic tool due to the non-specificity of clinical symptoms. This study aimed to identify clinical and EEG features related to NCSE in patients with msTBI. Methods: This was a cross-sectional study. Suspected NCSE in msTBI was examined using EEG data collected in consecutive patients from January 2017 to December 2019 at Dr. Cipto Mangunkusumo Hospital, Jakarta. Diagnoses of NCSE were made based on clinical manifestations and EEG features using the modified Salzburg Consensus Criteria for NCSE (mSCNC). Results: Of the 39 msTBI patients, 19 were diagnosed with NCSE; only two fulfilled the definitive criteria, and the remaining were possible NCSE. Delirium and perceptual impairment were only found in NCSE, while psychomotor agitation was higher (12.8% vs. 5.1% in NCSE vs. non-NCSE). The most common EEG feature was rhythmic activity (>0.5 Hz) without fluctuation, which improved with anti-epileptic drug administration. The Glasgow Coma Scale (GCS) score at onset and at hospitalisation discharge was significantly lower in patients with NCSE. The lesions in NCSE mostly originated from the temporal lobe. Injury to the temporal lobe had a significant relationship with NCSE occurrence (p ¼ 0.036, odds ratio 11.45 [95% confidence interval 1.17–111.6]). In this study, delirium, perceptual impairment, and psychomotor agitation were confirmed as NCSE using The most common discharge originated from the injured temporal lobe, and this site was a significant factor NCSE in patients with msTBI. in msTBI cases with clinical manifestations of altered mental status, psychomotor An injured temporal lobe was a susceptible site for the development of NCSE © 2021,Heliyon.All Rights Reserved. |
Altered mental status; Moderate-severe TBI; mSCNC; Non-convulsive status epilepticus |
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Elsevier Ltd |
24058440 |
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Article |
Q1 |
455 |
10919 |
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185 |
Kartika R.W., Alwi I., Suyatna F.D., Yunir E., Waspadji S., Immanuel S., Silalahi T., Sungkar S., Rachmat J., Reksodiputro M.H., Bardosono S. |
57223447932;15055173800;56039633100;36520254800;8678136400;57272979000;56275255400;57016857300;6507225348;35090488800;21933841000; |
The Role Of Vegf, Pdgf And Il-6 On Diabetic Foot Ulcer After Platelet Rich Fibrin Þ Hyaluronic Therapy |
2021 |
Heliyon |
7 |
9 |
e07934 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85120851420&doi=10.1016%2fj.heliyon.2021.e07934&partnerID=40&md5=0080e19d2c656e3452c7827d2fab24ba |
Doctoral Program in Medical Science, Faculty of Medicine, Universitas Indonesia, Indonesia; Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Clinical Pharmacology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Clinical Pathology, Faculty of Medicine, Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Internal Medicine, Krida Wacana Christian University, Jakarta, Indonesia; Department of Clinical Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Thorcic Cardiac and Vascular Surgery, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Facial Plastic Reconstructive Division, Department of Otorhinolaryngology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Nutrition, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Kartika, R.W., Doctoral Program in Medical Science, Faculty of Medicine, Universitas Indonesia, Indonesia; Alwi, I., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Suyatna, F.D., Department of Clinical Pharmacology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Yunir, E., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Waspadji, S., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Immanuel, S., Department of Clinical Pathology, Faculty of Medicine, Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Silalahi, T., Department of Internal Medicine, Krida Wacana Christian University, Jakarta, Indonesia; Sungkar, S., Department of Clinical Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Rachmat, J., Department of Thorcic Cardiac and Vascular Surgery, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Reksodiputro, M.H., Facial Plastic Reconstructive Division, Department of Otorhinolaryngology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Bardosono, S., Department of Nutrition, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Background: Current standard management of diabetic foot ulcers (DFUs) consists of surgical debridement followed by soak NaCl 0.9% gauzes tight infection and glycaemic control. Nowadays the use of advanced plateletrich fibrin (A-PRF) has emerged as an adjunctive method for treating DFUs. This study was conducted to demonstrate the ability of combine A-PRF þ HA as a complementary therapy in DFUs healing related with angiogenesis,inflammation and granulation index process. Methods: This open label randomized controlled trial was conducted in Koja District Hospital and Gatot Soebroto Hospital Jakarta, Indonesia on July 2019–April 2020. DFUs patients with wound duration of three months, Wagner-2, with size of ulcer less than 40 cm2 were included in the study. The number of subjects was calculated based on the rule of thumb and allocated randomly into three groups, namely topical A-PRF þ HA, A-PRF an Sodium Chloride 0.9% as a control, for each of 10 subjects. A-PRF made by 10 mL venous blood, centrifuge 200 G in 10 min, meanwhile A-PRF þ HA though mix both them with vertex machine around 5 min. Biomarker such as VEGF, PDGF and IL-6 examined from DFU taken by cotton swab and analysis using ELISA. Granulation Index was measured using ImageJ. Biomarkers and granulation index were evaluated on day 0, 3, 7 and 14. Data were analysed using SPSS version 20 with Anova and Kruskal Wallis test to compare the angiogenesis and inflammation effect between the three groups. Result: In topical dressing A-PRF þ HA, there is an increase in delta VEGF on day-3 (43.1 pg/mg protein) and day-7 (275,8 pg/mg protein) compared to A-PRF on day-3 (1.8 pg/mg protein) and day-7 (104.7 pg/mg protein), also NaCl (control) on day-3 (-4.9 pg/mg protein) and day-7 (28.3 pg/mg protein). So that the delta VEGF of A-PRF þ HA group increase significantly compared with others on day-3 (p ¼ 0.003) and day-7 (p < 0.001). Meanwhile APRF þ AH group, there is also a decrease in delta IL-6 after therapy on day-3 (-10.9 pg/mg protein) and day-7 (-18.3 pg/mg protein) compared to A-PRF in delta IL-6 on day-3 (-3.7 pg/mg protein) and on day-7 (-7.8 pg/ mg protein). In NaCl (control) group there is a increase delta IL-6 on day-3 (4.3 pg/mg protein) and on day-7 (35.5 pg/mg protein). So that the delta IL-6 of A-PRF þ HA group decrease significantly compared with others only on day-7 (p ¼ 0.015). In PDGF le level analysis, A-PRF þ HA group increase significantly (p ¼ 0.012) only in day -7 compare with other group (5.5 pg/mg protein). Conclusion: The study shows the superior role of combined A-PRF þ HA in the treatment DFU though increase angiogenesis and decrease inflammation pathway. The advantage of using A-PRF þ HA is that it accelerates wound healing by increasing granulation tissue compared to A-PRF alone © 2021 Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/) |
Diabetic foot ulcer; Hyaluronic acid; Platelet-rich fibrin |
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Elsevier Ltd |
24058440 |
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Article |
Q1 |
455 |
10919 |
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186 |
Sauriasari R., Madani R.A., Rozaliyani A., Sudiana D. |
16246507200;57367966600;57203065912;21934788800; |
The effect of repeated education using live demonstrations and videos of how to use inhalation drugs on quality of life for COPD patients |
2021 |
Heliyon |
7 |
9 |
e07870 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85120850425&doi=10.1016%2fj.heliyon.2021.e07870&partnerID=40&md5=9a57b37dd2d801600bfd6633e55ec700 |
Faculty of Pharmacy, Universitas Indonesia, Depok, West Java, Indonesia; Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Electrical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, Indonesia |
Sauriasari, R., Faculty of Pharmacy, Universitas Indonesia, Depok, West Java, Indonesia; Madani, R.A., Faculty of Pharmacy, Universitas Indonesia, Depok, West Java, Indonesia; Rozaliyani, A., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Sudiana, D., Department of Electrical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, Indonesia |
Repeated education regarding the proper use of inhalers can reduce the error rate in inhaler-using patients and improve COPD patients’ quality of life. This study investigates the effect of repeated education on the quality of life of COPD patients during the pandemic of COVID-19 from February to June 2020. Repeated education is provided using direct demonstrations to patients through educational media in the form of short videos made by the researchers for each inhaler type. This is a pre-experimental study design which was carried out prospectively at Grha Permata Ibu Hospital, Depok. The quality of life of 22 subjects was examined using the COPD assessmenttest (CAT) questionnaire. Each patient was given a direct verbal demonstration of the appropriate use of the inhaler. One month later, each patient was provided further education using less than 2 min of video sent to them online via the WhatsApp application. Final quality-of-life examination and assessment of inhaler technique were carried out three months after the initial examination. Assessment of proper inhaler technique was carried out using a specific checklist regarding the use of inhaler translated by the researcher. Before and after delivery of repeated education, the mean CAT score showed a decrease of two points, i.e., 12.8 ± 1.3 and 10.8 ± 2.0, respectively. This indicated that quality of life of the patients had significant improvement. However, as many as 63.6% of patients still made mistakes in using inhaler even though they had been educated. For DPI-type inhalers, mistake mostly happened at step “breath out gently, away from inhaler”. For pMDI-type inhalers, mistake mostly happened at step “while holding breath, remove inhaler from mouth”. It can be concluded that repeated education regarding proper inhaler technique with direct demonstrations and further maintained by videos can improve the quality of life in COPD patients. © 2021 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/bync-nd/4.0/). |
CAT (COPD Assessment test); Demonstration video; Inhaler; Repeated education |
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Elsevier Ltd |
24058440 |
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Article |
Q1 |
455 |
10919 |
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211 |
Angelin T.C., Bardosono S., Shinta D., Fahmida U. |
57235777300;21933841000;57237520500;14420783500; |
Growth, dietary intake, and vitamin D receptor (VDR) promoter genotype in Indonesian school-age children |
2021 |
Nutrients |
13 |
9 |
2904 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85113740878&doi=10.3390%2fnu13092904&partnerID=40&md5=c7a37360e57bb2d193a5b68571b677d7 |
Southeast Asian Ministers of Education Organization Regional Center for Food and Nutrition (SEAMEO RECFON)-Pusat Kajian Gizi Regional, Universitas Indonesia, Jakarta, 10430, Indonesia; Department of Nutrition, Faculty of Medicine, Universitas Indonesia—Dr. Cipto Mangunkusumo General Hospital, Jakarta, 10430, Indonesia |
Angelin, T.C., Southeast Asian Ministers of Education Organization Regional Center for Food and Nutrition (SEAMEO RECFON)-Pusat Kajian Gizi Regional, Universitas Indonesia, Jakarta, 10430, Indonesia, Department of Nutrition, Faculty of Medicine, Universitas Indonesia—Dr. Cipto Mangunkusumo General Hospital, Jakarta, 10430, Indonesia; Bardosono, S., Department of Nutrition, Faculty of Medicine, Universitas Indonesia—Dr. Cipto Mangunkusumo General Hospital, Jakarta, 10430, Indonesia; Shinta, D., Southeast Asian Ministers of Education Organization Regional Center for Food and Nutrition (SEAMEO RECFON)-Pusat Kajian Gizi Regional, Universitas Indonesia, Jakarta, 10430, Indonesia; Fahmida, U., Southeast Asian Ministers of Education Organization Regional Center for Food and Nutrition (SEAMEO RECFON)-Pusat Kajian Gizi Regional, Universitas Indonesia, Jakarta, 10430, Indonesia |
Nutrition has been known as a predominant factor associated with stunting. However, some studies have discovered a genetic contribution in calcium absorption that will affect growth, known as the VDR gene. The aim of this study was to assess the association between VDR gene polymorphism and dietary intake towards height-for-age z-score (HAZ) of elementary school children in Malang District, East Java. This study analyzed the baseline of a randomized trial in East Java, Indonesia. School children aged 8–10 years old (n = 142) were included in this study. Energy, protein, calcium, and vitamin D intakes were obtained using 4-day 24-h dietary recalls. Two SNPs located in the promoter region of VDR gene were selected (rs11568820 and rs4516035) and analyzed using Real-Time PCR. The result showed a significant correlation between energy and protein intake with HAZ of the children (p = 0.030 and p = 0.016, respectively). The association between VDR gene and HAZ was not found (p > 0.05). Adjusted by other factors, protein intake was significantly correlated with HAZ (β = 0.034, 95% CI 0.015–0.052, p < 0.001, adj. R2 = 0.089). The children in our study had a favorable VDR gene genotype, however the effect of VDR gene promoter activity might not be revealed due to very low vitamin D and calcium intake to stimulate intestinal calcium absorption which in turn affects HAZ. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
Calcium; Children; Dietary intake; Height-for-age z-score (HAZ); Indonesia; Stunting; VDR gene; Vitamin D |
calcium; DNA; protein; vitamin D; vitamin D receptor; calcitriol receptor; vitamin D; Article; body height; calcium absorption; calcium intake; caloric intake; child; child growth; controlled study; correlational study; cross-sectional study; diarrhea; dietary intake; elementary student; female; food frequency questionnaire; gene frequency; genetic variability; genotype; helminthiasis; heterozygote; human; Indonesia; macronutrient intake; male; micronutrient intake; pathogenesis; prevalence; primary school; promoter region; protein intake; randomized controlled trial; real time polymerase chain reaction; respiratory tract infection; school child; semi quantitative food frequency questionnaire; single nucleotide polymorphism; stunting; sun exposure; sunlight; vitamin intake; administration |
MDPI |
20726643 |
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34578782 |
Article |
Q1 |
1418 |
2497 |
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215 |
Dilogo I.H., Aditianingsih D., Sugiarto A., Burhan E., Damayanti T., Sitompul P.A., Mariana N., Antarianto R.D., Liem I.K., Kispa T., Mujadid F., Novialdi N., Luviah E., Kurniawati T., Lubis A.M.T., Rahmatika D. |
56161962800;56312263600;57189612291;36058554600;36058523500;57224505288;57194732286;57190862806;55802927800;56515348000;57204398571;57224555404;56114966200;55213290600;15122639800;57474077600; |
Umbilical cord mesenchymal stromal cells as critical COVID-19 adjuvant therapy: A randomized controlled trial |
2021 |
Stem Cells Translational Medicine |
10 |
9 |
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1279 |
1287 |
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8 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85107732762&doi=10.1002%2fsctm.21-0046&partnerID=40&md5=197659d90f645ca5130e69fcf16b7b4d |
Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Stem Cell and Tissue Engineering Research Cluster Indonesian Medical Education and Research Institute (IMERI) Universitas Indonesia, Jakarta, Indonesia; Department of Orthopaedic and Traumatology, Cipto Mangunkusumo General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Anesthesiology and Intensive Care Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Intensive Care Division, Universitas Indonesia Hospital, Depok, Indonesia; Department of Pulmonology and Respiratory Medicine, Faculty of Medicine Universitas Indonesia, Persahabatan General Hospital, Jakarta, Indonesia; Directorate of Medical Services, Nursing and Supporting, Sulianti Saroso Infection Disease Hospital, Jakarta, Indonesia; Directorate of Human Resources Development, Education and Operational Sulianti Saroso Infection Disease Hospital, Jakarta, Indonesia; Department of Histology, Universitas Indonesia Fakultas Kedokteran, Jakarta, Indonesia; Department of Anatomy, Universitas Indonesia Fakultas Kedokteran, Jakarta, Indonesia; Installation of Innovation Management and Intellectual Property, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Dilogo, I.H., Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Stem Cell and Tissue Engineering Research Cluster Indonesian Medical Education and Research Institute (IMERI) Universitas Indonesia, Jakarta, Indonesia, Department of Orthopaedic and Traumatology, Cipto Mangunkusumo General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Aditianingsih, D., Department of Anesthesiology and Intensive Care Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia, Intensive Care Division, Universitas Indonesia Hospital, Depok, Indonesia; Sugiarto, A., Department of Anesthesiology and Intensive Care Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Burhan, E., Department of Pulmonology and Respiratory Medicine, Faculty of Medicine Universitas Indonesia, Persahabatan General Hospital, Jakarta, Indonesia; Damayanti, T., Department of Pulmonology and Respiratory Medicine, Faculty of Medicine Universitas Indonesia, Persahabatan General Hospital, Jakarta, Indonesia; Sitompul, P.A., Directorate of Medical Services, Nursing and Supporting, Sulianti Saroso Infection Disease Hospital, Jakarta, Indonesia; Mariana, N., Directorate of Human Resources Development, Education and Operational Sulianti Saroso Infection Disease Hospital, Jakarta, Indonesia; Antarianto, R.D., Stem Cell and Tissue Engineering Research Cluster Indonesian Medical Education and Research Institute (IMERI) Universitas Indonesia, Jakarta, Indonesia, Department of Histology, Universitas Indonesia Fakultas Kedokteran, Jakarta, Indonesia; Liem, I.K., Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Stem Cell and Tissue Engineering Research Cluster Indonesian Medical Education and Research Institute (IMERI) Universitas Indonesia, Jakarta, Indonesia, Department of Anatomy, Universitas Indonesia Fakultas Kedokteran, Jakarta, Indonesia; Kispa, T., Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Mujadid, F., Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Novialdi, N., Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Luviah, E., Stem Cell and Tissue Engineering Research Cluster Indonesian Medical Education and Research Institute (IMERI) Universitas Indonesia, Jakarta, Indonesia; Kurniawati, T., Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Lubis, A.M.T., Department of Orthopaedic and Traumatology, Cipto Mangunkusumo General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Installation of Innovation Management and Intellectual Property, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rahmatika, D., Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
One of the main causes of acute respiratory distress syndrome in coronavirus disease 2019 (COVID-19) is cytokine storm, although the exact cause is still unknown. Umbilical cord mesenchymal stromal cells (UC-MSCs) influence proinflammatory T-helper 2 (Th2) cells to shift to an anti-inflammatory agent. To investigate efficacy of UC-MSC administration as adjuvant therapy in critically ill patients with COVID-19, we conducted a double-blind, multicentered, randomized controlled trial at four COVID-19 referral hospitals in Jakarta, Indonesia. This study included 40 randomly allocated critically ill patients with COVID-19; 20 patients received an intravenous infusion of 1 × 106/kg body weight UC-MSCs in 100 ml saline (0.9%) solution (SS) and 20 patients received 100 ml 0.9% SS as the control group. All patients received standard therapy. The primary outcome was measured by survival rate and/or length of ventilator usage. The secondary outcome was measured by clinical and laboratory improvement, with serious adverse events. Our study showed the survival rate in the UC-MSCs group was 2.5 times higher than that in the control group (P =.047), which is 10 patients and 4 patients in the UC-MSCs and control groups, respectively. In patients with comorbidities, UC-MSC administration increased the survival rate by 4.5 times compared with controls. The length of stay in the intensive care unit and ventilator usage were not statistically significant, and no adverse events were reported. The application of infusion UC-MSCs significantly decreased interleukin 6 in the recovered patients (P =.023). Therefore, application of intravenous UC-MSCs as adjuvant treatment for critically ill patients with COVID-19 increases the survival rate by modulating the immune system toward an anti-inflammatory state. © 2021 The Authors. STEM CELLS TRANSLATIONAL MEDICINE published by Wiley Periodicals LLC on behalf of AlphaMed Press. |
adjuvants; cord stem cell transplantation; COVID-19; cytokine release syndrome; immunology; mesenchymal stromal cells |
5' nucleotidase; azithromycin; C reactive protein; CD34 antigen; CD4 antigen; CD56 antigen; CD8 antigen; chemokine receptor CXCR3; D dimer; ferritin; fibrinogen; hemoglobin; interleukin 10; interleukin 6; lactic acid; leukemia inhibitory factor; oseltamivir; procalcitonin; Thy 1 membrane glycoprotein; vasculotropin; adjuvant therapy; adult; adult respiratory distress syndrome; Article; artificial ventilation; blood cell count; clinical article; clinical decision making; computer assisted tomography; controlled study; coronavirus disease 2019; critically ill patient; cytokine release syndrome; cytokine storm; double blind procedure; female; flow cytometry; fluid resuscitation; ground glass opacity; hematocrit; Horowitz index; human; hypotension; intensive care unit; length of stay; leukopen |
John Wiley and Sons Ltd |
21576564 |
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34102020 |
Article |
Q1 |
1781 |
1654 |
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216 |
Pawankar R., Thong B.Y.-H., Tiongco-Recto M., Wang J.-Y., Abdul Latiff A.H., Thien F., Oh J.-W., Kamchaisatian W., Rengganis I., Udwadia Z.F., Dhar R., Munkhbayarlakh S., Narantsetseg L., Le Pham D., Leung T.F., Zhang L., APAAACI COVID-19 Working Group |
7005904460;6603816215;55359899500;56499349900;55608026700;57204250177;55657464600;6505855073;8449988000;57192641184;7006700626;56800881300;8977752900;57201431490;57225672394;36068675900; |
Asia-Pacific perspectives on the COVID-19 pandemic |
2021 |
Allergy: European Journal of Allergy and Clinical Immunology |
76 |
9 |
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2998 |
2901 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85106213191&doi=10.1111%2fall.14894&partnerID=40&md5=a8dda5140c82a54f09e8a12b2804a47c |
Division of Allergy, Department of Pediatrics, Nippon Medical School, Tokyo, Japan; Department of Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, Singapore City, Singapore; Division of Allergy and Immunology, Department of Pediatrics, University of the Philippines-Philippine General Hospital, Manila, Philippines; Centre of Allergy and Clinical Immunology Research (ACIR), Department of Paediatrics, National Cheng Kung University Hospital, Tainan, Taiwan; Allergy & Immunology Centre Pantai Hospital, Kuala Lumpur, Malaysia; Department of Paediatrics, Universiti Putra Malaysia Teaching Hospital, Kuala Lumpur, Malaysia; Eastern Health, Monash University, Melbourne, Vic, Australia; Department of Pediatrics, Hanyang University Guri Hospital, Guri, Gyunggi-Do, South Korea; Pediatric Allergy and Immunology Division, Samitivej Children’s Hospital, Bangkok, Thailand; Division of Allergy and Clinical Immunology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, CiptoMangunkusumo General Hopsital, Jakarta, Indonesia; P.D. Hinduja National Hospital and Medical Research Centre and the Breach Candy Hospital, Mumbai, India; Department of Pulmonology, C K BIRLA Group of Hospitals, CMRIKolkata, India; Department of Pulmonology and Allergology, School of Medicine, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia; Department of Biochemistry, School of Biomedicine, MongolianNational University of Medical Sciences, Ulaanbaatar, Mongolia; Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Viet Nam; Department of Pediatrics, Chinese University of Hong Kong, Hong Kong; Department of Otolaryngology Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China |
Pawankar, R., Division of Allergy, Department of Pediatrics, Nippon Medical School, Tokyo, Japan; Thong, B.Y.-H., Department of Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, Singapore City, Singapore; Tiongco-Recto, M., Division of Allergy and Immunology, Department of Pediatrics, University of the Philippines-Philippine General Hospital, Manila, Philippines; Wang, J.-Y., Centre of Allergy and Clinical Immunology Research (ACIR), Department of Paediatrics, National Cheng Kung University Hospital, Tainan, Taiwan; Abdul Latiff, A.H., Allergy & Immunology Centre Pantai Hospital, Kuala Lumpur, Malaysia, Department of Paediatrics, Universiti Putra Malaysia Teaching Hospital, Kuala Lumpur, Malaysia; Thien, F., Eastern Health, Monash University, Melbourne, Vic, Australia; Oh, J.-W., Department of Pediatrics, Hanyang University Guri Hospital, Guri, Gyunggi-Do, South Korea; Kamchaisatian, W., Pediatric Allergy and Immunology Division, Samitivej Children’s Hospital, Bangkok, Thailand; Rengganis, I., Division of Allergy and Clinical Immunology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, CiptoMangunkusumo General Hopsital, Jakarta, Indonesia; Udwadia, Z.F., P.D. Hinduja National Hospital and Medical Research Centre and the Breach Candy Hospital, Mumbai, India; Dhar, R., Department of Pulmonology, C K BIRLA Group of Hospitals, CMRIKolkata, India; Munkhbayarlakh, S., Department of Pulmonology and Allergology, School of Medicine, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia; Narantsetseg, L., Department of Biochemistry, School of Biomedicine, MongolianNational University of Medical Sciences, Ulaanbaatar, Mongolia; Le Pham, D., Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Viet Nam; Leung, T.F., Department of Pediatrics, Chinese University of Hong Kong, Hong Kong; Zhang, L., Department of Otolaryngology Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China; APAAACI COVID-19 Working Group |
[No abstract available] |
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biological product; chloroquine; convalescent plasma; corticosteroid; hydroxychloroquine; immunosuppressive agent; lopinavir plus ritonavir; remdesivir; tocilizumab; asthma; chronic rhinosinusitis; coronavirus disease 2019; desensitization; device infection; eye allergy; health care access; health care policy; health care survey; human; immunosuppressive treatment; infection control; infection prevention; latex allergy; Letter; medical device complication; mutation; pandemic; phenotype; protective glasses; questionnaire; Asia; epidemiology; pandemic; Asia; COVID-19; Humans; Pandemics; SARS-CoV-2 |
John Wiley and Sons Inc |
01054538 |
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33948966 |
Letter |
Q1 |
3363 |
542 |
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217 |
Kurnia K.H., Elvioza, Sidik M., Sari T.T., Prihartono J., Sitorus R.S. |
57222405280;57205416912;56252760000;36519483600;6602605635;57221587271; |
Novel retinal findings in β-thalassemia major: older age and higher ferritin level as the risk factors |
2021 |
Graefe's Archive for Clinical and Experimental Ophthalmology |
259 |
9 |
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2633 |
2641 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102635685&doi=10.1007%2fs00417-021-05141-z&partnerID=40&md5=bf7abc1182072dd50cdf5ec7be6fa742 |
Department of Ophthalmology, Faculty of Medicine Universitas Indonesia - Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Department of Child Health, Faculty of Medicine Universitas Indonesia - Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Department of Community Medicine, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Kurnia, K.H., Department of Ophthalmology, Faculty of Medicine Universitas Indonesia - Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Elvioza, Department of Ophthalmology, Faculty of Medicine Universitas Indonesia - Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Sidik, M., Department of Ophthalmology, Faculty of Medicine Universitas Indonesia - Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Sari, T.T., Department of Child Health, Faculty of Medicine Universitas Indonesia - Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Prihartono, J., Department of Community Medicine, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Sitorus, R.S., Department of Ophthalmology, Faculty of Medicine Universitas Indonesia - Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia |
Purpose: To investigate retinal changes in β-thalassemia major patients and identify their association with systemic risk factors. Methods: In this prospective study, 120 β-thalassemia major patients received complete ophthalmic examinations (best-corrected visual acuity, contrast sensitivity, color vision, and indirect ophthalmoscopy) and retinal imaging using color fundus photography and fundus autofluorescence imaging. Patients were grouped according to the presence of thalassemia-related retinal changes. The association between systemic risk factors (age, type and duration of iron chelator use, history of splenectomy, hemoglobin level, and ferritin level) and thalassemia-related retinal changes was investigated using logistic regression analysis. Results: Thalassemia-related retinal changes were identified in 36.7% of patients. Several distinct retinal changes were observed, including retinal refractile bodies in 10% of patients and retinal hemorrhage in 5.8% of patients. Fundus autofluorescence imaging showed abnormal patterns in 36.3% of patients with thalassemia-related retinal changes and 18.4% of patients without thalassemia-related retinal changes. Age (odds ratio [OR] = 1.10, 95% confidence interval [CI] 1.03–1.18) and ferritin level (OR 1.16, 95% CI 1.01–1.33) were associated with thalassemia-related retinal changes. Conclusion: Novel retinal changes were observed in β-thalassemia major patients. This study identified older age and higher ferritin level as risk factors for thalassemia-related retinal changes. © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature. |
Ferritin; Fundus autofluorescence imaging; Iron chelator; Retinal changes; β-Thalassemia major |
deferasirox; deferiprone; deferoxamine; ferritin; hemoglobin; ferritin; adult; age; angioid streak; Article; autofluorescence imaging; best corrected visual acuity; blood transfusion; branch retinal vein occlusion; color vision; contrast sensitivity; controlled study; drusen; epithelium hyperplasia; eye fundus; eye photography; female; ferritin blood level; hemoglobin blood level; human; Indonesia; major clinical study; male; melanocytosis; observational study; ophthalmoscopy; optic disk anomaly; optical coherence tomography; papilledema; patient history of surgery; prospective study; retina disease; retina examination; retina hemorrhage; retina pigment degeneration; slit lamp microscopy; splenectomy; subretinal neovascularization; thalassemia major; treatment duration; aged; beta thalasse |
Springer Science and Business Media Deutschland GmbH |
0721832X |
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33738624 |
Article |
Q1 |
1196 |
3322 |
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219 |
Amarra M.S., Chong M.F.-F., Titapant V., Somprasit C., Rogacion J., Irwinda R., Huynh T.N.K., Nalliah S. |
26024123300;16302916300;6602085502;8440614700;6508291071;57205713130;57221814418;25422423000; |
ILSI Southeast Asia symposium: prevalence, risk factors, and actions to address gestational diabetes in selected Southeast Asian countries |
2021 |
European Journal of Clinical Nutrition |
75 |
9 |
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1303 |
1308 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100287487&doi=10.1038%2fs41430-020-00838-6&partnerID=40&md5=968eff6db95c2d745843171831db19e3 |
Department of Food Science and Nutrition, College of Home Economics, University of the Philippines Diliman, Quezon, Philippines; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore; Department of Obstetrics and Gynecology, Faculty of Medicine, Siriraj Hospital Mahidol University, Bangkok, Thailand; Department of Obstetrics and Gynecology, Faculty of Medicine, Thammasat University, Bangkok, Thailand; Department of Pediatrics, University of the Philippines, Manila, Philippines; Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Obstetrics and Gynecology, Pham Ngoc Thach University of Medicine, Ho Chi Minh, Viet Nam; Division of Obstetrics & Gynaecology, Clinical School, International Medical University, Seremban, Malaysia |
Amarra, M.S., Department of Food Science and Nutrition, College of Home Economics, University of the Philippines Diliman, Quezon, Philippines; Chong, M.F.-F., Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore; Titapant, V., Department of Obstetrics and Gynecology, Faculty of Medicine, Siriraj Hospital Mahidol University, Bangkok, Thailand; Somprasit, C., Department of Obstetrics and Gynecology, Faculty of Medicine, Thammasat University, Bangkok, Thailand; Rogacion, J., Department of Pediatrics, University of the Philippines, Manila, Philippines; Irwinda, R., Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Huynh, T.N.K., Department of Obstetrics and Gynecology, Pham Ngoc Thach University of Medicine, Ho Chi Minh, Viet Nam; Nalliah, S., Division of Obstetrics & Gynaecology, Clinical School, International Medical University, Seremban, Malaysia |
[No abstract available] |
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trace element; anthropometry; Brunei Darussalam; Cambodia; diet therapy; dietary intake; female; gestational weight gain; health care planning; human; Indonesia; Laos; Malaysia; Myanmar; nutritional assessment; Philippines; physical activity; practice guideline; pregnancy diabetes mellitus; prevalence; Review; risk factor; risk reduction; Singapore; Southeast Asian; symposium; Thailand; Viet Nam; pregnancy; pregnancy diabetes mellitus; Southeast Asia; Asia, Southeastern; Diabetes, Gestational; Female; Humans; Pregnancy; Prevalence; Risk Factors |
Springer Nature |
09543007 |
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33531635 |
Review |
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1024 |
4241 |
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220 |
Castro-Calvo J., King D.L., Stein D.J., Brand M., Carmi L., Chamberlain S.R., Demetrovics Z., Fineberg N.A., Rumpf H.-J., Yücel M., Achab S., Ambekar A., Bahar N., Blaszczynski A., Bowden-Jones H., Carbonell X., Chan E.M.L., Ko C.-H., de Timary P., Dufour M., Grall-Bronnec M., Lee H.K., Higuchi S., Jimenez-Murcia S., Király O., Kuss D.J., Long J., Müller A., Pallanti S., Potenza M.N., Rahimi-Movaghar A., Saunders J.B., Schimmenti A., Lee S.-Y., Siste K., Spritzer D.T., Starcevic V., Weinstein A.M., Wölfling K., Billieux J. |
55883443800;57214845145;55769747595;7202584047;56059576800;24723599200;55882733400;35413253200;7004528536;7006258831;43860942100;35749590300;56118752900;57220353000;15834239200;35232657000;35344453600;8716479100;25821757600;7103106444;57209334001;8600274900;7202930847;7801631922;57000322900;41762055600;57190689045;56472199900;57207496581;7006591634;8696686900;7402341830;36089370500;36760834000;55644113100;24463790800;7005374306;7201680411;23973806500;57220421868; |
Expert appraisal of criteria for assessing gaming disorder: an international Delphi study |
2021 |
Addiction |
116 |
9 |
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2463 |
2475 |
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24 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099942594&doi=10.1111%2fadd.15411&partnerID=40&md5=284445a20e0a947af8166f3091d96aea |
Department of Personality, Assessment, and Psychological Treatments, University of Valencia, Spain; College of Education, Psychology, and Social Work, Flinders University, Australia; SAMRC Unit on Risk and Resilience in Mental Disorders, Department of Psychiatry and Neuroscience Institute, University of Cape Town, Cape Town, South Africa; General Psychology: Cognition and Center for Behavioral Addiction Research (CeBAR), University Duisburg-Essen, Germany; The Data Science Institute, Inter-disciplinary Center, Herzliya, Israel; Department of Psychiatry, Faculty of Medicine, University of Southampton, Southampton, United Kingdom; Southern Health NHS Foundation Trust, Southampton, United Kingdom; Institute of Psychology, ELTE Eötvös Loránd University, Budapest, Hungary; University of Hertfordshire, Hatfield, UK, Hertfordshire Partnership University NHS Foundation Trust, Welwyn Garden City, United Kingdom; University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom; Department of Psychiatry and Psychotherapy, University of Luebeck, Luebeck, Germany; BrainPark, School of Psychological Sciences, Turner Institute for Brain and Mental Health and Monash Biomedical Imaging Facility, Monash University, Melbourne, VIC, Australia; Specialized Facility In Behavioral Addictions, ReConnecte, Department of Psychiatry, University Hospitals of Geneva, Generva, Switzerland; Faculty of Medicine, Geneva University, Geneva, Switzerland; National Drug Dependence Treatment Centre, All India Institute of Medical Sciences, New Delhi, India; Department of Psychiatry and Mental Health, Hospital Selayang, Ministry of Health, Malaysia; Faculty of Science, Brain and Mind Centre, School of Psychology, University of Sydney, Sydney, Australia; National Centre for Gaming Disorders, London, United Kingdom; University College London, London, United Kingdom; Faculty of Psychology, Education and Sports Sciences Blanquerna, Ramon Llull University, Barcelona, Spain; St John's Cathedral Counselling Service, and Division on Addiction, Hong Kong; Department of Psychiatry, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung City, Taiwan; Department of Adult Psychiatry, Institute of Neuroscience, UCLouvain and Cliniques Universitaires Saint-Luc, Brussels, Belgium; Université du Québec à Montréal, Montréal, QC, Canada; CHU Nantes, Department of Addictology and Psychiatry, Nantes, France; Universités de Nantes et Tours, UMR 1246, Nantes, France; Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, South Korea; National Hospital Organization, Kurihama Medical and Addiction Center, Japan; Department of Psychiatry, Bellvitge University Hospital-IDIBELL, Barcelona, Spain; Ciber Fisiopatología Obesidad y Nutrición (CIBERObn), Instituto de Salud Carlos III, Madrid, Spain; International Gaming Research Unit, Psychology Department, Nottingham Trent University, Nottingham, United Kingdom; Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Laboratory for Experimental Psychopathology, Psychological Science Research Institute, Université Catholique de Louvain, Louvain, Belgium; Department of Psychosomatic Medicine and Psychotherapy, Hannover Medical School, Hanover, Germany; Neuroscience Institute, University of Florence, Italy; Departments of Psychiatry and Neuroscience and the Child Study Center, Yale School of Medicine and Connecticut Mental Health Center, New Haven, CT, United States; Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran; Centre for Youth Substance Abuse Research, University of Queensland, Brisbane, QLD, Australia; Faculty of Human and Social Sciences, Kore University of Enna, Enna, Italy; Department of Psychiatry, Eunpyeong St Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea; Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Postgraduate Program in Psychiatry and Behavioral Sciences, Federal University of Rio Grande do Sul, Brazil; Faculty of Medicine and Health, Sydney Medical School, Nepean Clinical School, University of Sydney, Sydney, Australia; Department of Behavioral Science, Ariel University, Israel; Outpatient Clinic for Behavioral Addictions, Department of Psychosomatic Medicine and Psychotherapy, University Medical Center of the Johannes Gutenberg-University Mainz, Germany; Institute of Psychology, University of Lausanne, Lausanne, Switzerland; Health and Behaviour Institute, University of Luxembourg, Esch-sur-Alzette, Luxembourg |
Castro-Calvo, J., Department of Personality, Assessment, and Psychological Treatments, University of Valencia, Spain; King, D.L., College of Education, Psychology, and Social Work, Flinders University, Australia; Stein, D.J., SAMRC Unit on Risk and Resilience in Mental Disorders, Department of Psychiatry and Neuroscience Institute, University of Cape Town, Cape Town, South Africa; Brand, M., General Psychology: Cognition and Center for Behavioral Addiction Research (CeBAR), University Duisburg-Essen, Germany; Carmi, L., The Data Science Institute, Inter-disciplinary Center, Herzliya, Israel; Chamberlain, S.R., Department of Psychiatry, Faculty of Medicine, University of Southampton, Southampton, United Kingdom, Southern Health NHS Foundation Trust, Southampton, United Kingdom; Demetrovics, Z., Institute of Psychology, ELTE Eötvös Loránd University, Budapest, Hungary; Fineberg, N.A., University of Hertfordshire, Hatfield, UK, Hertfordshire Partnership University NHS Foundation Trust, Welwyn Garden City, United Kingdom, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom; Rumpf, H.-J., Department of Psychiatry and Psychotherapy, University of Luebeck, Luebeck, Germany; Yücel, M., BrainPark, School of Psychological Sciences, Turner Institute for Brain and Mental Health and Monash Biomedical Imaging Facility, Monash University, Melbourne, VIC, Australia; Achab, S., Specialized Facility In Behavioral Addictions, ReConnecte, Department of Psychiatry, University Hospitals of Geneva, Generva, Switzerland, Faculty of Medicine, Geneva University, Geneva, Switzerland; Ambekar, A., National Drug Dependence Treatment Centre, All India Institute of Medical Sciences, New Delhi, India; Bahar, N., Department of Psychiatry and Mental Health, Hospital Selayang, Ministry of Health, Malaysia; Blaszczynski, A., Faculty of Science, Brain and Mind Centre, School of Psychology, University of Sydney, Sydney, Australia; Bowden-Jones, H., National Centre for Gaming Disorders, London, United Kingdom, University College London, London, United Kingdom; Carbonell, X., Faculty of Psychology, Education and Sports Sciences Blanquerna, Ramon Llull University, Barcelona, Spain; Chan, E.M.L., St John's Cathedral Counselling Service, and Division on Addiction, Hong Kong; Ko, C.-H., Department of Psychiatry, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung City, Taiwan; de Timary, P., Department of Adult Psychiatry, Institute of Neuroscience, UCLouvain and Cliniques Universitaires Saint-Luc, Brussels, Belgium; Dufour, M., Université du Québec à Montréal, Montréal, QC, Canada; Grall-Bronnec, M., CHU Nantes, Department of Addictology and Psychiatry, Nantes, France, Universités de Nantes et Tours, UMR 1246, Nantes, France; Lee, H.K., Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, South Korea; Higuchi, S., National Hospital Organization, Kurihama Medical and Addiction Center, Japan; Jimenez-Murcia, S., Department of Psychiatry, Bellvitge University Hospital-IDIBELL, Barcelona, Spain, Ciber Fisiopatología Obesidad y Nutrición (CIBERObn), Instituto de Salud Carlos III, Madrid, Spain; Király, O., Institute of Psychology, ELTE Eötvös Loránd University, Budapest, Hungary; Kuss, D.J., International Gaming Research Unit, Psychology Department, Nottingham Trent University, Nottingham, United Kingdom; Long, J., Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China, Laboratory for Experimental Psychopathology, Psychological Science Research Institute, Université Catholique de Louvain, Louvain, Belgium; Müller, A., Department of Psychosomatic Medicine and Psychotherapy, Hannover Medical School, Hanover, Germany; Pallanti, S., Neuroscience Institute, University of Florence, Italy; Potenza, M.N., Departments of Psychiatry and Neuroscience and the Child Study Center, Yale School of Medicine and Connecticut Mental Health Center, New Haven, CT, United States; Rahimi-Movaghar, A., Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran; Saunders, J.B., Centre for Youth Substance Abuse Research, University of Queensland, Brisbane, QLD, Australia; Schimmenti, A., Faculty of Human and Social Sciences, Kore University of Enna, Enna, Italy; Lee, S.-Y., Department of Psychiatry, Eunpyeong St Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea; Siste, K., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Spritzer, D.T., Postgraduate Program in Psychiatry and Behavioral Sciences, Federal University of Rio Grande do Sul, Brazil; Starcevic, V., Faculty of Medicine and Health, Sydney Medical School, Nepean Clinical School, University of Sydney, Sydney, Australia; Weinstein, A.M., Department of Behavioral Science, Ariel University, Israel; Wölfling, K., Outpatient Clinic for Behavioral Addictions, Department of Psychosomatic Medicine and Psychotherapy, University Medical Center of the Johannes Gutenberg-University Mainz, Germany; Billieux, J., Institute of Psychology, University of Lausanne, Lausanne, Switzerland, Health and Behaviour Institute, University of Luxembourg, Esch-sur-Alzette, Luxembourg |
Background and aims: Following the recognition of ‘internet gaming disorder’ (IGD) as a condition requiring further study by the DSM-5, ‘gaming disorder’ (GD) was officially included as a diagnostic entity by the World Health Organization (WHO) in the 11th revision of the International Classification of Diseases (ICD-11). However, the proposed diagnostic criteria for gaming disorder remain the subject of debate, and there has been no systematic attempt to integrate the views of different groups of experts. To achieve a more systematic agreement on this new disorder, this study employed the Delphi expert consensus method to obtain expert agreement on the diagnostic validity, clinical utility and prognostic value of the DSM-5 criteria and ICD-11 clinical guidelines for GD. Methods: A total of 29 international experts with clinical and/or research experience in GD completed three iterative rounds of a Delphi survey. Experts rated proposed criteria in progressive rounds until a pre-determined level of agreement was achieved. Results: For DSM-5 IGD criteria, there was an agreement both that a subset had high diagnostic validity, clinical utility and prognostic value and that some (e.g. tolerance, deception) had low diagnostic validity, clinical utility and prognostic value. Crucially, some DSM-5 criteria (e.g. escapism/mood regulation, tolerance) were regarded as incapable of distinguishing between problematic and non-problematic gaming. In contrast, ICD-11 diagnostic guidelines for GD (except for the criterion relating to diminished non-gaming interests) were judged as presenting high diagnostic validity, clinical utility and prognostic value. Conclusions: This Delphi survey provides a foundation for identifying the most diagnostically valid and clinically useful criteria for GD. There was expert agreement that some DSM-5 criteria were not clinically relevant and may pathologize non-problematic patterns of gaming, whereas ICD-11 diagnostic guidelines are likely to diagnose GD adequately and avoid pathologizing. © 2021 The Authors. Addiction published by John Wiley & Sons Ltd on behalf of Society for the Study of Addiction. |
Delphi; diagnosis; DSM; gaming disorder; ICD; internet gaming disorder |
addiction; Delphi study; Diagnostic and Statistical Manual of Mental Disorders; human; impulse control disorder; Internet; video game; Behavior, Addictive; Delphi Technique; Diagnostic and Statistical Manual of Mental Disorders; Disruptive, Impulse Control, and Conduct Disorders; Humans; Internet; Video Games |
John Wiley and Sons Inc |
09652140 |
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33449441 |
Article |
Q1 |
2424 |
961 |
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221 |
Qu L.G., Perera M., Lawrentschuk N., Umbas R., Klotz L. |
57204687809;56544134500;57217501609;6602634832;55040556500; |
Scoping review: hotspots for COVID-19 urological research: what is being published and from where? |
2021 |
World Journal of Urology |
39 |
9 |
|
3151 |
3160 |
|
2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85090474581&doi=10.1007%2fs00345-020-03434-2&partnerID=40&md5=02d48bd6f6edec3e634ad6f1c71c4628 |
Olivia Newton John Cancer Research Institute, Austin Health, Melbourne, VIC, Australia; Department of Surgery, University of Melbourne, Melbourne, VIC, Australia; Department of Urology, Austin Health, Heidelberg, VIC, Australia; Department of Urology, The Royal Melbourne Hospital, Melbourne, VIC, Australia; EJ Whitten Prostate Cancer Research Centre at Epworth, Melbourne, VIC, Australia; Department of Urology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada |
Qu, L.G., Olivia Newton John Cancer Research Institute, Austin Health, Melbourne, VIC, Australia, Department of Surgery, University of Melbourne, Melbourne, VIC, Australia, Department of Urology, Austin Health, Heidelberg, VIC, Australia; Perera, M., Olivia Newton John Cancer Research Institute, Austin Health, Melbourne, VIC, Australia, Department of Surgery, University of Melbourne, Melbourne, VIC, Australia; Lawrentschuk, N., Department of Surgery, University of Melbourne, Melbourne, VIC, Australia, Department of Urology, The Royal Melbourne Hospital, Melbourne, VIC, Australia, EJ Whitten Prostate Cancer Research Centre at Epworth, Melbourne, VIC, Australia; Umbas, R., Department of Urology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Klotz, L., Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada |
Purpose: Contemporary, original research should be utilised to inform guidelines in urology relating to the COVID-19 pandemic. This comprehensive review aimed to: identify all up-to-date original publications relating to urology and COVID-19, characterise where publications were from, and outline what topics were investigated. Methods: This review utilised a search strategy that assessed five electronic databases, additional grey literature, and global trial registries. All current published, in-press, and pre-print manuscripts were included. Eligible studies were required to be original research articles of any study design, reporting on COVID-19 or urology, in any of study population, intervention, comparison, or outcomes. Included studies were reported in a narrative synthesis format. Data were summarised according to primary reported outcome topic. A world heatmap was generated to represent where included studies originated from. Results: Of the 6617 search results, 48 studies met final inclusion criteria, including 8 pre-prints and 7 ongoing studies from online registries. These studies originated from ten countries according to first author affiliation. Most studies originated from China (n = 13), followed by Italy (n = 12) and USA (n = 11). Topics of the study included pathophysiological, administrative, and clinical fields: translational (n = 14), COVID-19-related outcomes (n = 5), urology training (n = 4), telemedicine (n = 7), equipment and safety (n = 2), urology in general (n = 4), uro-oncology (n = 3), urolithiasis (n = 1), and kidney transplantation (n = 8). Conclusion: This review has outlined available original research relevant to COVID-19 and urology from the international community. This summary may serve as a guide for future research priorities in this area. © 2020, Springer-Verlag GmbH Germany, part of Springer Nature. |
COVID-19; Kidney transplantation; Telemedicine; Training; Uro-oncology; Urology |
epidemiology; global health; human; kidney transplantation; medical research; oncology; organization and management; prevention and control; procedures; publishing; telemedicine; urology; Biomedical Research; COVID-19; Global Health; Humans; Kidney Transplantation; Medical Oncology; Publishing; SARS-CoV-2; Telemedicine; Urology |
Springer Science and Business Media Deutschland GmbH |
07244983 |
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32909171 |
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Q1 |
1552 |
2143 |
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