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    Publikasi Scopus 926 artikel (Per 14 Maret 2022)

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    395 Dilogo I.H., Pawitan J.A., Tobing J.F.L., Fiolin J., Luviah E. 56161962800;6508348067;36167767600;57194498274;56114966200; Amount of bone morphogenetic protein-2, epidermal growth factor, and vascular endothelial growth factor in adipose tissue, umbilical cord, and bone marrow mesenchymal stem cell derived secretome: An in-vitro study 2021 Stem Cells in Disease Pathogenesis 187 206 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85114959444&partnerID=40&md5=456465470c35e0929cc2d9166da2405e Department of Orthopaedic and Traumatology, Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas Indonesia, Indonesia; Department of Histology, Faculty of Medicine Universitas Indonesia, Indonesia; Stem Cell and Tissue Engineering Research Center, Indonesian Medical Education and Research Institute (IMERI), Universitas Indonesia, Indonesia Dilogo, I.H., Department of Orthopaedic and Traumatology, Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas Indonesia, Indonesia; Pawitan, J.A., Department of Histology, Faculty of Medicine Universitas Indonesia, Indonesia; Tobing, J.F.L., Department of Orthopaedic and Traumatology, Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas Indonesia, Indonesia; Fiolin, J., Department of Orthopaedic and Traumatology, Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas Indonesia, Indonesia; Luviah, E., Stem Cell and Tissue Engineering Research Center, Indonesian Medical Education and Research Institute (IMERI), Universitas Indonesia, Indonesia [No abstract available] Nova Science Publishers, Inc. 9781536196580; 9781536196306 Book Chapter #N/A #N/A #N/A
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    628 Paradisa R.H., Bustamam A., Victor A.A., Yudantha A.R., Sarwinda D. 57221562575;36815737800;57191055282;55489644900;56119401500; Diabetic Retinopathy Detection using Deep Convolutional Neural Network with Visualization of Guided Grad-CA 2021 Proceedings - 2021 4th International Conference on Computer and Informatics Engineering: IT-Based Digital Industrial Innovation for the Welfare of Society, IC2IE 2021 19 24 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85124286346&doi=10.1109%2fIC2IE53219.2021.9649326&partnerID=40&md5=e35e1e6e90a4eda5a153a1a2f916ec18 Universitas Indonesia, Faculty of Mathematics and Natural Science, Department of Mathematics, Depok, Indonesia; Universitas Indonesia Cipto Mangunkusumo National General Hospital, Faculty of Medicine, Department of Ophthalmology, Jakarta, Indonesia Paradisa, R.H., Universitas Indonesia, Faculty of Mathematics and Natural Science, Department of Mathematics, Depok, Indonesia; Bustamam, A., Universitas Indonesia, Faculty of Mathematics and Natural Science, Department of Mathematics, Depok, Indonesia; Victor, A.A., Universitas Indonesia Cipto Mangunkusumo National General Hospital, Faculty of Medicine, Department of Ophthalmology, Jakarta, Indonesia; Yudantha, A.R., Universitas Indonesia, Faculty of Mathematics and Natural Science, Department of Mathematics, Depok, Indonesia; Sarwinda, D., Universitas Indonesia, Faculty of Mathematics and Natural Science, Department of Mathematics, Depok, Indonesia One of the complications of diabetes that represents a serious threat to world health is Diabetic Retinopathy (DR). High blood sugar levels in people with diabetes can damage the blood vessels in the retina and causing blindness. DR can be detected by examining the fundus image by an ophthalmologist. However, the limited number of ophthalmologists who can analyze fundus image is an obstacle because the number of DR sufferers continues to increase. Therefore, an automated system is needed to help doctors diagnose the disease. Researchers have developed deep learning techniques as Artificial Intelligence (AI) approach to finding DR in fundus images. In this research, we use the Deep Convolutional Neural Networks method with InceptionV3 structure and various optimizers such as the Stochastic Gradient Descent with Momentum (SGDM), Root Mean Square Propagation (RMSprop), and Adaptive Moment Estimation (Adam). The fundus image dataset previously through the augmentation and preprocessing steps to make it easier for the model to recognize the image. The InceptionV3 model with the Adam optimizer gave the best results in detecting DR lesions from the Kaggle dataset with 96% accuracy. This paper also presents a Grad-CAM guided activation map that can describe the position of the suspicious lesion to explain the results of DR detection. © 2021 IEEE. deep convolutional neural network; diabetic retinopathy; guided grad-cam Backpropagation; Blood vessels; Convolution; Convolutional neural networks; Eye protection; Gradient methods; Health risks; Image segmentation; Optimization; Stochastic systems; Automated systems; Blood sugar levels; Diabetic retinopathy; Fundus image; Guided grad-cam; Learning techniques; Moment estimation; Neural network method; Optimizers; Stochastic gradient descent; Deep neural networks Institute of Electrical and Electronics Engineers Inc. 9781665442886 Conference Paper #N/A #N/A #N/A
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    00015385(1)
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    926 Pranata R., Tondas A.E., Yonas E., Vania R., Yamin M., Chandra A., Siswanto B.B. 57201973901;57211111907;57201987097;57208328436;23475706300;37025699200;14422648800; Differences in clinical characteristics and outcome of de novo heart failure compared to acutely decompensated chronic heart failure–systematic review and meta-analysis 2021 Acta Cardiologica 76 4 410 420 4 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85083567065&doi=10.1080%2f00015385.2020.1747178&partnerID=40&md5=e965cfa89cbc748fb0b3f9ae692b173b Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia; Department of Cardiology and Vascular Medicine, Faculty of Medicine Universitas Sriwijaya, Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia; Faculty of Medicine, Universitas YARSI, Jakarta, Indonesia; Division of Cardiology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Cardiology Division, University of Texas Southwestern Medical Center, Dallas, TX, United States; Department of Cardiology and Vascular Medicine, Faculty of Medicine Universitas Indonesia, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia Pranata, R., Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia; Tondas, A.E., Department of Cardiology and Vascular Medicine, Faculty of Medicine Universitas Sriwijaya, Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia; Yonas, E., Faculty of Medicine, Universitas YARSI, Jakarta, Indonesia; Vania, R., Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia; Yamin, M., Division of Cardiology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Chandra, A., Cardiology Division, University of Texas Southwestern Medical Center, Dallas, TX, United States; Siswanto, B.B., Department of Cardiology and Vascular Medicine, Faculty of Medicine Universitas Indonesia, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia Background: Recent evidence showed that the characteristics and outcome of those with de novo heart failure (HF) and acutely decompensated chronic heart failure (ADCHF) were different. We aimed to perform a comprehensive search on the clinical characteristics and outcome of patients with de novo HF and ADCHF. Methods: We performed a comprehensive search on de novo/new onset acute HF vs ADCHF from inception up until December 2019. Results: There were 38320 patients from 15 studies. De novo HF were younger and, had less prevalent hypertension, diabetes mellitus, ischaemic heart disease, chronic obstructive pulmonary disease, atrial fibrillation, and history of stroke/transient ischaemic attack compared to ADCHF. Five studies showed a lower NT-proBNP in de novo HF patients, while one study showed no difference. Valvular heart disease as aetiology of heart failure was less frequent in de novo HF, and upon sensitivity analysis, hypertensive heart disease was more frequent in de novo HF. As for precipitating factors, ACS (OR 2.42; I2:89%) was more frequently seen in de novo HF, whereas infection was less frequently (OR 0.69; I2:32%) in ADCHF. De novo HF was associated with a significantly lower 3-month mortality (OR 0.63; I2:91%) and 1-year (OR 0.59; I2:59%) mortality. Meta-regression showed that 1-year mortality did not significantly vary with age (p =.106), baseline ejection fraction (p =.703), or HF reduced ejection fraction (p =.262). Conclusion: Risk factors, aetiology, and precipitating factors of HF in de novo and ADCHF differ. De novo HF also had lower 1-year mortality and 3-month mortality compared to ADCHF. © 2020 Belgian Society of Cardiology. acute decompensated heart failure; acute heart failure; characteristics; De novo heart failure; mortality; new onset heart failure amino terminal pro brain natriuretic peptide; creatinine; hemoglobin; acute coronary syndrome; acutely decompensated chronic heart failure; Article; atrial fibrillation; cardiovascular infection; cardiovascular mortality; cerebrovascular accident; Charlson Comorbidity Index; chronic obstructive lung disease; clinical feature; clinical outcome; coronary artery disease; de novo heart failure; diabetes mellitus; estimated glomerular filtration rate; heart arrhythmia; heart ejection fraction; heart failure; heart failure with reduced ejection fraction; hospital mortality; human; hypertension; ischemic heart disease; meta analysis; mortality rate; prevalence; risk factor; sensitivity analysis; smoking; systematic review; transient ischemic attack; valvular heart disease Taylor and Francis Ltd. 00015385 32252602 Article Q3 348 13410
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    00016071(3)
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    194 Mansyur M. 37085506800; Occupational health, productivity and evidence-based workplace health intervention 2021 Acta Medica Philippina 55 6 602 603 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85116680924&doi=10.47895%2fAMP.V55I6.4273&partnerID=40&md5=e8cf11e83c91edd4e2dccb08e749b070 Department of Community Medicine, Faculty of Medicine, Universitas Indonesia Mansyur, M., Department of Community Medicine, Faculty of Medicine, Universitas Indonesia [No abstract available] University of the Philippines Manila 00016071 Editorial Q4 128 25603
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    195 Habiburrahman M., Lesmana E., Harmen F., Gratia N., Mirtha L.T. 57320844200;57208440285;57288593800;57288763400;57193201450; The impact of sleep deprivation on work performance towards night-shift healthcare workers: An evidence-based case report 2021 Acta Medica Philippina 55 6 650 664 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85116676334&doi=10.47895%2fAMP.V55I6.3157&partnerID=40&md5=279c9c6f812ba7d9e6cf09363847268d Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Hospital of Universitas Indonesia, Depok, Indonesia Habiburrahman, M., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Lesmana, E., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Harmen, F., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Gratia, N., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Mirtha, L.T., Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Hospital of Universitas Indonesia, Depok, Indonesia Background. Poor sleep and excessive fatigue among workers can reduce well-being and physical fitness. However, not many studies have mentioned how sleeping deprivation among night-shift healthcare workers impacted their work performance in multiple aspects. Method. We conducted an evidence-based case report (EBCR) of a night shift nurse who was worried about the impact of her sleep deprivation on her work performance in the future due to prior history of needle-stick injuries. We aimed to determine whether sleeping deprivation caused by regular night shifts leads to decreased work performance among night-shift healthcare workers by formulating a clinical question. Evidence was searched systematically using five major journal databases (Proquest, EBSCO-Host, PubMed, ScienceDirect, and Cochrane) and was assessed thoroughly using inclusion and exclusion criteria. Results. Eleven eligible studies were obtained with a medium level of evidence (III-IV), three systematic reviews with meta-analyses (SR-MA), three SR without MA, and five observational studies. All of them were analyzed and critically appraised using Oxford Evidence-Based Medicine and Joanna Briggs Institute tools. We found that reduced quantity and quality of sleep impacted all dimensions of work performance among healthcare professionals, be it in task performance (e.g., skill proficiency), contextual performance (e.g., communication skill and mental health issues), and patient and health worker safety (accident and medication error). It could also encourage counterproductive work behavior, such as absenteeism. Furthermore, sleep deprivation changes circadian rhythms, causing decreased information processing and affective recognition functions in some vital brain areas, ultimately affecting several work dimensions. Conclusion. In conclusion, stakeholders need to adjust proper shift scheduling for health care workers, practice sleep hygiene, maintain physical fitness, and consume nutritional food, positively correlated to health and productivity. © 2021 University of the Philippines Manila. All rights reserved. Evidence-based medicine; Healthcare worker; Night shift; Sleep deprivation; Work performance University of the Philippines Manila 00016071 Article Q4 128 25603
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    196 Alie I.R., Andriantoro H., Timan I.S., Sulistomo A.W., Illyas E.I., Mansyur M. 57288933200;55037171500;6602793366;57024018500;57288423500;37085506800; Potency biomarker effect of endothelial microparticles (emps) for early prediction of cardiovascular risk in shift worker nurses 2021 Acta Medica Philippina 55 6 616 620 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85116671512&doi=10.47895%2fAMP.V55I6.3142&partnerID=40&md5=10ceaf9c58aabc0ce93083d831644fe1 Program of Universitas Indonesia; Department of Cardiology and Vascular Faculty of Medicine, Universitas Indonesia; Department of Pathology Clinic, Faculty of Medicine, Universitas Indonesia; Department of Community Medicine, Faculty of Medicine, Universitas Indonesia; Department of Physiology, Faculty of Medicine, Universitas Indonesia Alie, I.R., Program of Universitas Indonesia; Andriantoro, H., Department of Cardiology and Vascular Faculty of Medicine, Universitas Indonesia; Timan, I.S., Department of Pathology Clinic, Faculty of Medicine, Universitas Indonesia; Sulistomo, A.W., Department of Community Medicine, Faculty of Medicine, Universitas Indonesia; Illyas, E.I., Department of Physiology, Faculty of Medicine, Universitas Indonesia; Mansyur, M., Department of Community Medicine, Faculty of Medicine, Universitas Indonesia Objectives. Shift work results in changing worker's behavior, food, and sleep patterns, which can cause circadian rhythm disturbance, which is a cardiovascular risk. Until now, a biomarker of early prediction of cardiovascular risk on shift workers is still not developed. This study aimed to assess the cardiovascular risk of shift worker nurses by detecting endothelial microparticles (EMPs). Methods. This longitudinal study compared six shift nurses and five non-shift nurses by measuring the EMPs using antigen CD31+ flow cytometry. All met the inclusion criteria consisting of 28 blood samples followed in one week shift. Results. EMPs among non-shift nurses were below 200 μL. However, shift nurses' EMPs increased above 200 μL with Man-Whitney U p = 0.000 on days 4 and 7 following a one shift per week schedule. Conclusion. There was an increase in shift workers' endothelial microparticles (EMP) which was a sign of cardiovascular risk. © 2021 University of the Philippines Manila. All rights reserved. Cardiovascular risk; CD31+; Endothelial microparticles (EMPs); Nurse; Shift work University of the Philippines Manila 00016071 Article Q4 128 25603
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    00016489(1)
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    919 Adham M., Aldino N., Zahra S., Rachmadi L., Bardosono S. 14024202100;57219533691;57219536231;55062422000;21933841000; Feasibility of p16 surrogate biomarker as adjunct diagnosis of oral and oropharyngeal malignancy in a resource-constrained country 2021 Acta Oto-Laryngologica 141 1 106 110 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85093677891&doi=10.1080%2f00016489.2020.1821915&partnerID=40&md5=eb216333808982b0694f8695f96c5a55 Head and Neck Oncology Division, Department of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Nutrition, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia Adham, M., Head and Neck Oncology Division, Department of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Aldino, N., Department of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Zahra, S., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Rachmadi, L., Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Bardosono, S., Department of Nutrition, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia Background: Cases of Human papillomavirus (HPV)-associated oral and oropharyngeal cancer are increasing. Proper diagnostic tools are required to detect HPV among patients, especially in areas where high technology is lacking. Aims: To provide mapping of HPV prevalence in Southeast Asia and to determine the effectivity of p16 as a surrogate biomarker for HPV infection in oral and oropharyngeal cancer. Methods: Medical records of 56 patients diagnosed with oral and oropharyngeal squamous cell carcinomas (SCC) were reviewed. HPV PCR DNA and p16 immunohistochemistry (IHC) examination were performed to detect HPV positivity. Results: HPV PCR prevalence in oropharyngeal SCC is 42.9% and 28.6% in oral SCC. P16 IHC has 67% sensitivity and 75% specificity in detecting HPV in oropharyngeal cancer, and 33% and 72% in oral cancer. Conclusion: We conclude that p16 IHC with a 5% cut-off can be used as a surrogate biomarker for oropharyngeal SCC, but not oral SCC, in areas where resources are restricted. However, further diagnostic tools may be needed. © 2020 Acta Oto-Laryngologica AB (Ltd). HPV; Oral cancer; oropharyngeal cancer; p16 protein p16; virus DNA; cyclin dependent kinase inhibitor 2A; tumor marker; adult; aged; Article; awareness; controlled study; diagnostic test accuracy study; female; human; human tissue; immunohistochemistry; Indonesian; major clinical study; male; medical record; mouth squamous cell carcinoma; oropharynx squamous cell carcinoma; papillomavirus infection; polymerase chain reaction; prevalence; priority journal; sensitivity and specificity; Southeast Asia; feasibility study; head and neck tumor; metabolism; middle aged; oropharynx tumor; Adult; Aged; Biomarkers, Tumor; Cyclin-Dependent Kinase Inhibitor p16; Feasibility Studies; Female; Head and Neck Neoplasms; Humans; Immunohistochemistry; Male; Middle Aged; Oropharyngeal Neoplasms; Squamous Cell Carcinoma of Head and Neck Taylor and Francis Ltd. 00016489 33085553 Article Q2 609 8285
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    00029637(3)
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    97 Miranda A.V., Wiyono L., Rocha I.C.N., Cedeño T.D.D., Lucero-Prisno D.E., III 57222664687;57207889054;57223283646;57224097138;56051373800; Strengthening virology research in the association of Southeast Asian nations: Preparing for future pandemics 2021 American Journal of Tropical Medicine and Hygiene 105 5 1141 1143 1 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85119604704&doi=10.4269%2fajtmh.21-0589&partnerID=40&md5=98ad7364acccdc95ee57ef0ea9e65ed9 Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; School of Medicine, Centro Escolar University, Manila, Philippines; Department of Global Health and Development, London School of Hygiene and Tropical Medicine, London, United Kingdom; Faculty of Management and Development Studies, University of the Philippines Open University, Los Baños, Laguna, Philippines Miranda, A.V., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Wiyono, L., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Rocha, I.C.N., School of Medicine, Centro Escolar University, Manila, Philippines; Cedeño, T.D.D., School of Medicine, Centro Escolar University, Manila, Philippines; Lucero-Prisno, D.E., III, Department of Global Health and Development, London School of Hygiene and Tropical Medicine, London, United Kingdom, Faculty of Management and Development Studies, University of the Philippines Open University, Los Baños, Laguna, Philippines The Association of Southeast Asian Nations (ASEAN) region is known to be a global hotspot to viral outbreaks because of many factors. To limit the impact of future outbreaks, it is crucial for the ASEAN governments to strengthen regional virology research capacity. The ASEAN governments have collaborated in several virology initiatives, with the most recent being the establishment of the ASEAN Regional Center for Public Health Emergencies and Emerging Diseases. However, several challenges, including technology disparities, nationalistic tendencies, and the lack of public acceptance toward virus sharing, need to be addressed to maximize the region’s collaboration potential in virology research. We recommend the governments to 1) prioritize the strengthening of research capacities; 2) develop stronger cooperation and possible centralization of efforts on top of national capacities; 3) develop an equitable and secure research framework; and 4) improve the public awareness regarding the importance of regional public health responses. Copyright © 2021 by The American Society of Tropical Medicine and Hygiene epidemic; human; medical research; organization and management; pandemic; Southeast Asia; virology; Asia, Southeastern; Biomedical Research; Disease Outbreaks; Humans; Pandemics; Virology American Society of Tropical Medicine and Hygiene 00029637 34506300 Article Q1 1015 4298
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    147 Merati T.P., Karyana M., Tjitra E., Kosasih H., Aman A.T., Alisjahbana B., Lokida D., Arlinda D., Maldarelli F., Neal A., Arif M., Gasem M.H., Lukman N., Sudarmono P., Lau C.-Y., Hadi U., Lisdawati V., Wulan W.N., Lane H.C., Siddiqui S. 57203678680;24449083500;57204151009;6507043017;6701594071;6506944516;57190663838;57218444330;57210198407;57220466230;56740206600;6508371601;57190737414;6507855437;16245242000;55804160500;56786334300;57204491118;57197596240;8707129300; Prevalence of HIV infection and resistance mutations in patients hospitalized for febrile illness in Indonesia 2021 American Journal of Tropical Medicine and Hygiene 105 4 960 965 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117017901&doi=10.4269%2fajtmh.20-1595&partnerID=40&md5=f52639e32eebbadb71cd505b119b26d4 Faculty of Medicine, Universitas Udayana, Denpasar, Indonesia; National Institute of Health Research and Development, Ministry of Health, Republic of Indonesia, Jakarta, Indonesia; Indonesia Research Partnership on Infectious Disease (INA-RESPOND), Jakarta, Indonesia; Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia; Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia; Department of Clinical Pathology, Tangerang District Hospital, Tangerang, Indonesia; National Cancer Institute, National Institutes of Health, Bethesda, MD, United States; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States; Faculty of Medicine, Universitas Hasanudin, Makassar, Indonesia; Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia; Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; Sulianti Saroso, Infectious Disease Hospital, Jakarta, Indonesia; Indonesia Research Partnership on Infections Disease, Jalan Percetakan Negara No. 29, Jakarta, 10560, Indonesia Merati, T.P., Faculty of Medicine, Universitas Udayana, Denpasar, Indonesia; Karyana, M., National Institute of Health Research and Development, Ministry of Health, Republic of Indonesia, Jakarta, Indonesia, Indonesia Research Partnership on Infectious Disease (INA-RESPOND), Jakarta, Indonesia; Tjitra, E., National Institute of Health Research and Development, Ministry of Health, Republic of Indonesia, Jakarta, Indonesia; Kosasih, H., Indonesia Research Partnership on Infectious Disease (INA-RESPOND), Jakarta, Indonesia, Indonesia Research Partnership on Infections Disease, Jalan Percetakan Negara No. 29, Jakarta, 10560, Indonesia; Aman, A.T., Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia; Alisjahbana, B., Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia; Lokida, D., Department of Clinical Pathology, Tangerang District Hospital, Tangerang, Indonesia; Arlinda, D., National Institute of Health Research and Development, Ministry of Health, Republic of Indonesia, Jakarta, Indonesia, Indonesia Research Partnership on Infectious Disease (INA-RESPOND), Jakarta, Indonesia; Maldarelli, F., National Cancer Institute, National Institutes of Health, Bethesda, MD, United States; Neal, A., National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States; Arif, M., Faculty of Medicine, Universitas Hasanudin, Makassar, Indonesia; Gasem, M.H., Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia; Lukman, N., Indonesia Research Partnership on Infectious Disease (INA-RESPOND), Jakarta, Indonesia; Sudarmono, P., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Lau, C.-Y., National Cancer Institute, National Institutes of Health, Bethesda, MD, United States; Hadi, U., Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; Lisdawati, V., Sulianti Saroso, Infectious Disease Hospital, Jakarta, Indonesia; Wulan, W.N., Indonesia Research Partnership on Infectious Disease (INA-RESPOND), Jakarta, Indonesia; Lane, H.C., National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States; Siddiqui, S., National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States HIV prevalence in Indonesia is increasing, and only 64% of infected individuals know their status. In a prospective cohort of 1,453 hospitalized patients with unexplained fever, 46 (3.2%) had HIV, including 15 (1.1%) patients without a prior HIV diagnosis. Among 31 subjects previously known to have HIV, 21 (68%) had been receiving combination antiretroviral therapy (cART) at the time of enrollment. Of 39 HIV cases with HIV RNA levels $ 100 copies/mL, sequencing for genotype analysis and resistance testing was successful in 30 (77%) subjects. The most common HIV subtypes were AE (90%) and B (10%). Five (16.7%) subjects had resistance mutations to nucleoside and non-nucleoside reverse transcriptase inhibitors, and all of them were on cART. No evidence of transmitted drug resistance was found in newly diagnosed individuals. Hospital-based screening may be an efficient method to expand HIV testing and identify a significant number of new cases. Access to care, close monitoring, expansion of anti-retroviral options, and ensuring availability of CD4 determinations, viral load testing, and genotyping are crucial to control of the epidemic in Indonesia. © 2021 by The American Society of Tropical Medicine and Hygiene nonnucleoside reverse transcriptase inhibitor; RNA directed DNA polymerase inhibitor; virus RNA; anti human immunodeficiency virus agent; adolescent; adult; aged; antiretroviral therapy; Article; child; cohort analysis; combination drug therapy; female; fever; genotype; hospital patient; hospitalization; human; Human immunodeficiency virus infection; Indonesia; major clinical study; male; nonhuman; prevalence; prospective study; virus mutation; virus resistance; antiviral resistance; drug effect; genetics; Human immunodeficiency virus 1; Human immunodeficiency virus infection; infant; middle aged; mutation; preschool child; very elderly; virology; young adult; Adolescent; Adult; Aged; Aged, 80 and over; Anti-HIV Agents; Child; Child, Preschool; Drug Resistance, Viral; Female; HIV Infection American Society of Tropical Medicine and Hygiene 00029637 34460416 Article Q1 1015 4298
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    203 Sasmono R.T., Johar E., Yohan B., Ma’Roef C.N., Soebandrio A., Myint K.S.A., Pronyk P., Hadinegoro S.R., Soepardi E.J., Bouckenooghe A., Hawley W., Rosenberg R., Powers A.M. 57245712300;57204001174;55843037500;6507740388;8602893200;7003758970;6602466584;57226218772;57191174412;18233281300;7004280510;35578810900;7005770718; In Response: Stability of zika virus antibodies in specimens from a retrospective serological study 2021 American Journal of Tropical Medicine and Hygiene 105 3 853 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115293744&doi=10.4269%2fajtmh.21-0564b&partnerID=40&md5=4b5e07961e6006f21355f4fdf73c7fa8 Eijkman Institute for Molecular Biology, Jakarta, Indonesia; UNICEF Indonesia, Jakarta, Indonesia; Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia; Ministry of Health of the Republic of Indonesia, Jakarta, Indonesia; Sanofi Pasteur Lyon, Rhone-Alpes, France; Centers for Disease Control and Prevention, Atlanta, GA, United States; Centers for Disease Control and Prevention Fort, Collins, CO, United States Sasmono, R.T., Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Johar, E., Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Yohan, B., Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Ma’Roef, C.N., Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Soebandrio, A., Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Myint, K.S.A., Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Pronyk, P., UNICEF Indonesia, Jakarta, Indonesia; Hadinegoro, S.R., Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia; Soepardi, E.J., Ministry of Health of the Republic of Indonesia, Jakarta, Indonesia; Bouckenooghe, A., Sanofi Pasteur Lyon, Rhone-Alpes, France; Hawley, W., Centers for Disease Control and Prevention, Atlanta, GA, United States; Rosenberg, R., Centers for Disease Control and Prevention Fort, Collins, CO, United States; Powers, A.M., Centers for Disease Control and Prevention Fort, Collins, CO, United States [No abstract available] immunoglobulin G antibody; virus antibody; enzyme linked immunosorbent assay; freezing; Letter; plaque reduction neutralization test; serology; storage; Zika virus; human; retrospective study; serodiagnosis; Zika fever; Humans; Neutralization Tests; Retrospective Studies; Zika Virus; Zika Virus Infection American Society of Tropical Medicine and Hygiene 00029637 34314374 Letter Q1 1015 4298
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