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559 |
Kesuma Y., Sekartini R., Timan I.S., Kurniawan A., Bardosono S., Firmansyah A., Vandenplas Y. |
57209278648;57224503576;6602793366;6506883360;21933841000;6602915502;57223670656; |
Irritable bowel syndrome in Indonesian adolescents |
2021 |
Jornal de Pediatria |
97 |
2 |
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197 |
203 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85081734309&doi=10.1016%2fj.jped.2020.02.001&partnerID=40&md5=b8d2dcd5c96832dce29f4c05c71dd219 |
Sriwijaya University and Moh Hoesin Hospital, Faculty of Medicine, Department of Pediatrics, Palembang, Indonesia; University of Indonesia and Cipto Mangunkusumo Hospital, Faculty of Medicine, Department of Pediatrics, Jakarta, Indonesia; University of Indonesia Cipto Mangunkusumo Hospital, Faculty of Medicine, Department of Clinical Pathology, Jakarta, Indonesia; University of Indonesia, Faculty of Medicine, Department of Parasitology, Jakarta, Indonesia; University of Indonesia, Faculty of Medicine, Department of Nutrition, Jakarta, Indonesia; Free University of Brussels, UZ Brussel Hospital, KidZ Health Castle, Brussels, Belgium |
Kesuma, Y., Sriwijaya University and Moh Hoesin Hospital, Faculty of Medicine, Department of Pediatrics, Palembang, Indonesia; Sekartini, R., University of Indonesia and Cipto Mangunkusumo Hospital, Faculty of Medicine, Department of Pediatrics, Jakarta, Indonesia; Timan, I.S., University of Indonesia Cipto Mangunkusumo Hospital, Faculty of Medicine, Department of Clinical Pathology, Jakarta, Indonesia; Kurniawan, A., University of Indonesia, Faculty of Medicine, Department of Parasitology, Jakarta, Indonesia, University of Indonesia, Faculty of Medicine, Department of Nutrition, Jakarta, Indonesia; Bardosono, S., University of Indonesia, Faculty of Medicine, Department of Nutrition, Jakarta, Indonesia; Firmansyah, A., University of Indonesia and Cipto Mangunkusumo Hospital, Faculty of Medicine, Department of Pediatrics, Jakarta, Indonesia; Vandenplas, Y., Free University of Brussels, UZ Brussel Hospital, KidZ Health Castle, Brussels, Belgium |
Objective: Irritable bowel syndrome is a frequent functional gastrointestinal disorder. The aims of this study were to investigate its epidemiology, focusing on the role of intestinal mucosal integrity and to evaluate the impact on the quality of life. Methods: A community-based survey applying a comparative cross sectional approach was conducted in six high schools in Palembang. Subjects were recruited using multistage random sampling divided in two groups. Rome III criteria were used to establish a diagnosis of IBS in combination with a questionnaire to determine risk factors. Determination of fecal alpha-1-antitrypsin and calprotectin levels was performed to determine impaired intestinal mucosal integrity. A questionnaire was used to evaluate how quality of life was affected by irritable bowel syndrome. Results: The survey was performed in 454 14−18 years old adolescents, of whom 30.2% fulfilled the Rome III criteria for IBS, with the following subtypes: 36.5% diarrhea, 18.9% constipation, 21.9% mixed, and 22.6% unclassified. Major risk factors were female gender, bullying, age 14–16 years, history of constipation and diarrhea, eating nuts, and drinking coffee, tea, and soft drinks. There was a significant association with intestinal inflammation (p = 0.013). A significantly impaired quality of life was found (p = 0.001). Conclusions: The prevalence of irritable bowel syndrome in adolescents was high, with bullying, female gender, age 14–16 years, constipation and diarrhea, and dietary consumption of soft drinks, coffee, and tea as risk factors. A significant association with intestinal inflammation was found. © 2020 Sociedade Brasileira de Pediatria |
Adolescent; Intestinal integrity; Irritable bowel syndrome; Quality of life |
alpha 1 antitrypsin; calgranulin; adolescent; adult; age; Article; avoidance behavior; body image; bullying; clinical evaluation; coffee consumption; comparative study; constipation; controlled study; cross-sectional study; data analysis software; diarrhea; digestive system disease assessment; disease association; dysphoria; enteritis; feces level; female; gender; high school; human; human activities; human relation; Indonesia; Indonesian; intestine mucosa; Irritable Bowel Syndrome Quality of Life questionnaire; irritable colon; major clinical study; male; nut; patient worry; pediatric patient; prevalence; quality of life; quality of life assessment; risk factor; Rome III criteria; sexual behavior; social behavior; soft drink; tea consumption; constipation; irritable colon; questionnaire; |
Elsevier Editora Ltda |
00217557 |
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