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Id	Authors	Full Names	Author S Id	Title	Year	Source Title	Volume	Issue	Art No	Page Start	Page End	Page Count	Cited By	Link	Affiliations	Authors With Affiliations	Abstract	Author Keywords	Index Keywords	Funding Details	Funding Text	Publisher	Issn	Isbn	Pubmed Id	Document Type	Sjr Best Quartile	Sjr	Sjr Rank
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304	Ambarsari C.G.; Tandri C.C.; Situmorang G.R.	Ambarsari, Cahyani Gita (57211850895); Tandri, Chika Carnation (58612308600); Situmorang, Gerhard Reinaldi (57190001213)	57211850895; 58612308600; 57190001213	Urinary extracellular vesicles: Potential biomarkers for vesicoureteral reflux	2024	Vesicoureteral Reflux: From Diagnosis to Treatment				1	31	30	0	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85188558589&partnerID=40&md5=8a9d50d7da10ee591511aac119604866	Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Child Health, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; University of Nottingham, Nottingham, United Kingdom; Medical Technology Cluster, Indonesian Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Urology, Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Ambarsari C.G., Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Department of Child Health, Cipto Mangunkusumo Hospital, Jakarta, Indonesia, University of Nottingham, Nottingham, United Kingdom, Medical Technology Cluster, Indonesian Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Tandri C.C., Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Situmorang G.R., Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Department of Urology, Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Vesicoureteral reflux (VUR) is characterized by the backward flow of urine from the bladder to the upper urinary tract, causing kidney damage if left untreated. However, the current diagnostic method, voiding cystourethrography (VCUG), is invasive, potentially risky, and may cause anxiety, especially for young patients and their caregivers. Urinary extracellular vesicles (uEVs) are small vesicles originating from the renal tubular system that carry lipids, proteins, and RNAs for intercellular communication and regulation. uEVs have emerged as promising human biofluid-derived biomarkers in various kidney diseases. This chapter explores the potential of uEVs as noninvasive biomarkers for diagnosing VUR, monitoring its progression, and determining the extent of kidney damage. Previously, serum inflammatory markers have been identified as factors associated with kidney fibrosis in reflux nephropathy, but these may simply be a reflection of systemic inflammation rather than of a specific condition. Meanwhile, current research on uEVs in VUR remains limited. One study has identified vitronectin, a uEV-derived protein, as a predictor of VUR induced by spinal cord injury (sensitivity = 80%, specificity = 82.9%, area under the curve (AUC) = 0.795). Another study, focusing on pediatric VUR, showed that patients with kidney fibrosis had significantly higher urinary neutrophil gelatinaseassociated lipocalin (uNGAL) values than those without kidney fibrosis (1.49 ng/mL vs. 0.58 ng/mL, p < 0.001). However, apart from kidney fibrosis, uNGAL also increases in the contexts of AKI and pediatric urinary tract infections, indicating that uNGAL is not specific as a single marker for VUR. These findings highlight the importance of identifying biomarkers derived from entities, such as uEVs, that are specific to the urinary system and are not affected by systemic factors In summary, uEVs offer crucial insights into urinary tract processes and have broad potential for diagnosing, treating, and forecasting kidney and urinary tract diseases, including VUR. Future studies to test their role should encompass larger sample sizes, standardized protocols, and rigorous validation. © 2024 Nova Science Publishers, Inc. All rights reserved.	Diagnostic; Fibrosis; Invasive; Kidney damage; Urinary tract				Nova Science Publishers, Inc.		979-889113505-5; 979-889113444-7		Book chapter	#N/A	#N/A	#N/A	View
320	Laurentius A.; Siagian S.N.	Laurentius, Andrea (57213147353); Siagian, Sisca Natalia (57214134720)	57213147353; 57214134720	Management of arrhythmia in chronic heart failure	2024	Pathophysiology, Risk Factors, and Management of Chronic Heart Failure				295	309	14	0	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85198408116&doi=10.1016%2fB978-0-12-822972-9.00040-7&partnerID=40&md5=396514226b291e19c64371b1addc7ae4	Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; National Cardiovascular Center Harapan Kita, Jakarta, Indonesia	Laurentius A., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Siagian S.N., National Cardiovascular Center Harapan Kita, Jakarta, Indonesia	Management of chronic heart failure has been much more complex due to emergence of challenge in the treatment of heart failure and the underlying etiology simultaneously. The presence of arrhythmia may have adverse effects on long-term cardiac remodeling. Arrhythmia in chronic heart failure is exacerbated by overstimulation of neurohormonal system, which causes oxidative stress, inflammation, electrolyte imbalance, aggravating risk of increased arrhythmogenesis. As increase in QRS and QT prolongation predispose arrhythmogenesis, various types of tachyarrhythmia require guideline in the management to be specifically tailored to heart failure patients, such as adenosine in terminating supraventricular tachycardia, beta blocker for atrial fibrillation in heart failure, or class 1C antiarrhythmic medication for stable ventricular tachycardia. Furthermore, dysfunction of pacemaker nodes favors and needs arrhythmia complication. Patients with heart failure who developed arrhythmias present major artificial pacemaker installed with resynchronization mode, resolving conduction block in strained heart tissues. Understanding pathophysiology of arrhythmia classification in heart failure may assist in choosing appropriate management for patients, with increase in quality of life in these patients and reducing rate of morbidity and mortality. © 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.	Arrhythmia; cardiac remodeling; chronic heart failure; electrocardiographic features; management; pathophysiology; sudden cardiac death				Elsevier		978-012822972-9; 978-012823111-1		Book chapter	#N/A	#N/A	#N/A	View
347	Mendel B.	Mendel, Brian (57221914088)	57221914088	Congenital heart diseases	2024	Pathophysiology, Risk Factors, and Management of Chronic Heart Failure				235	241	6	0	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85198448113&doi=10.1016%2fB978-0-12-822972-9.00008-0&partnerID=40&md5=48038dbfbb12ec5abee34bb259721448	Department of Cardiology and Vascular Medicine, Sultan Sulaiman Government Hospital, North Sumatera, Indonesia; Faculty of Medicine, University of Indonesia, Jakarta, Indonesia	Mendel B., Department of Cardiology and Vascular Medicine, Sultan Sulaiman Government Hospital, North Sumatera, Indonesia, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia	Heart failure (HF) is the final common pathway of all cardiac pathologies. However, conventional description of HF spectrum is always within the settings of ischemic, hypertensive, valvular, and myopathic diseases presented to the underappreciation of the essential subgroups of patients with HF, those with corrected or uncorrected congenital heart diseases (CHDs). Moreover, increasing research recognition of HF in patients with CHD in the shifting epidemiology from pediatric to adult in the CHD populations due to the advance in surgical and medical management had not been balanced with adequate expansion in both research and public health practices. Thus, the objective of this chapter was to focus on how the pathophysiology of patients with CHD progresses into HF with the intention of highlighting important gaps in the knowledge.; HF can develop early in life prior to one or more residual substrates from underlying or surgically corrected cardiac defect result in accumulated cardiac pressure and volume overload. Understanding of complex cardiac and respiratory physiology in CHD pathophysiology is extremely essential in managing these patients. © 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.	Congenital heart disease; heart failure; pressure overload; systemic right ventricle; volume overload				Elsevier		978-012822972-9; 978-012823111-1		Book chapter	#N/A	#N/A	#N/A	View
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493	Purwoto G.; Aprilia B.; Kayika I.P.G.; Elvira S.D.; Rahardjo H.E.; Nuranna L.	Purwoto, Gatot (14720170400); Aprilia, Bella (57210283261); Kayika, I. Putu Gede (57224684808); Elvira, Sylvia D. (57192888533); Rahardjo, Harrina E. (37762030000); Nuranna, Laila (55301184300)	14720170400; 57210283261; 57224684808; 57192888533; 37762030000; 55301184300	Surveillance of Indonesian female sexual function after hysterectomy	2024	Indian Journal of Cancer	61	1		98	104	6	0	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85193014722&doi=10.4103%2fijc.IJC_269_21&partnerID=40&md5=bda539257ee3474b176f1c696e93fcec	Department of Obstetrics and Gynecology, Faculty of Medicine, Dr. Cipto Mangunkusumo Hospital, University of Indonesia, Jakarta, Indonesia; Department of Psychiatry, Faculty of Medicine, Dr. Cipto Mangunkusumo Hospital, University of Indonesia, Jakarta, Indonesia; Department of Urology, Faculty of Medicine, Dr. Cipto Mangunkusumo Hospital, University of Indonesia, Jakarta, Indonesia	Purwoto G., Department of Obstetrics and Gynecology, Faculty of Medicine, Dr. Cipto Mangunkusumo Hospital, University of Indonesia, Jakarta, Indonesia; Aprilia B., Department of Obstetrics and Gynecology, Faculty of Medicine, Dr. Cipto Mangunkusumo Hospital, University of Indonesia, Jakarta, Indonesia; Kayika I.P.G., Department of Obstetrics and Gynecology, Faculty of Medicine, Dr. Cipto Mangunkusumo Hospital, University of Indonesia, Jakarta, Indonesia; Elvira S.D., Department of Psychiatry, Faculty of Medicine, Dr. Cipto Mangunkusumo Hospital, University of Indonesia, Jakarta, Indonesia; Rahardjo H.E., Department of Urology, Faculty of Medicine, Dr. Cipto Mangunkusumo Hospital, University of Indonesia, Jakarta, Indonesia; Nuranna L., Department of Obstetrics and Gynecology, Faculty of Medicine, Dr. Cipto Mangunkusumo Hospital, University of Indonesia, Jakarta, Indonesia	Background: Sexual function is one component of quality of life that could be fulfilled by humans. Hysterectomy, which is an operative procedure in women, may cause disturbance in sexual function. Aim: This study aims to determine the surveillance of sexual function after hysterectomy. Methods: This is a cross-sectional study involving 92 gynecological tumor patients who had undergone a hysterectomy by open laparotomy procedure for at least 3 months. Evaluation of sexual dysfunction using the female sexual function index (FSFI-6) questionnaire, which assesses sexual function in the form of sexual disorder, sexual dysfunction, desire disorders, stimulation, orgasm disorders, and pain. The study was conducted in September-November 2018 in Dr. Cipto Mangunkusumo Hospital, Jakarta. The patients were divided into total and radical hysterectomy groups and whether castration was performed. Results: The total group had 71 total hysterectomy and 21 radical hysterectomy patients. Sexual dysfunction (radical hysterectomy 47.6%, n = 10/21; total hysterectomy 28.2%, n = 20/71; castration 33.8%, n = 24/71; and without castration 28.6%, n = 6/21); orgasmic disorders (total hysterectomy 28.2%, n = 20/71; radical hysterectomy 47.6%, n = 10/21; castration 33.8%, n = 24/71; without castration 28.6%, n = 6/21); and pain disorder (radical hysterectomy 28.6%, n = 6/21; compared with 9.9%, n = 7/71 total hysterectomy). Conclusion: No significant differences were found between sexual function after radical hysterectomy and total hysterectomy, as well as between the castration groups. Based on these findings, sexual function is an important reference for health professionals to be considered in conducting counseling before and after surgery. © 2023 Indian Journal of Cancer.	Castration; female sexual function index; radical hysterectomy; sexual function; total hysterectomy	adult; anorgasmia; Article; body mass; castration; cross-sectional study; female; female sexual arousal disorder; Female Sexual Function Index; health practitioner; human; hypoactive sexual desire disorder; hysterectomy; Indonesian; laparotomy; major clinical study; monitoring; ovary cancer; psychogenic pain; pubic symphysis; quality of life; radical hysterectomy; sexual dysfunction; sexual function; total hysterectomy; uterus myoma			Wolters Kluwer Medknow Publications	0019509X		38090969	Article	Q4	246	17024	View
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95	Sukor N.; Sunthornyothin S.; Tran T.V.; Tarigan T.J.; Mercado-Asis L.B.; Sum S.; Aung M.W.; Yong A.M.L.; Tedjo T.; Villa M.; Khaing N.E.E.; Azizan E.A.; Kang W.H.; Lim V.; Teo A.E.D.; Zhang M.; Tran H.; Puar T.H.	Sukor, Norlela (23969589600); Sunthornyothin, Sarat (6507106810); Tran, Thang V (57452764800); Tarigan, Tri Juli (36057746500); Mercado-Asis, Leilani B (6602441282); Sum, Satha (59177614300); Aung, Moe Wint (57225889658); Yong, Alice M. L (36520258200); Tedjo, Tania (59177459000); Villa, Michael (56265865600); Khaing, Nang Ei Ei (56358841100); Azizan, Elena Aisha (26538651700); Kang, Waye Hann (57210785835); Lim, Vivien (55340585600); Teo, Ada E. D (56004524300); Zhang, Meifen (57217073677); Tra	23969589600; 6507106810; 57452764800; 36057746500; 6602441282; 59177614300; 57225889658; 36520258200; 59177459000; 56265865600; 56358841100; 26538651700; 57210785835; 55340585600; 56004524300; 57217073677; 59177614400; 55324849600	Health Care Challenges in the Management of Primary Aldosteronism in Southeast Asia	2024	Journal of Clinical Endocrinology and Metabolism	109	7		1718	1725	7	0	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85196323366&doi=10.1210%2fclinem%2fdgae039&partnerID=40&md5=b67fdbbb013fa2d8838b2f25e8d0e84a	Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, 50300, Malaysia; Department of Medicine, Hospital Canselor Tuanku Muhriz, Kuala Lumpur, 56000, Malaysia; Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand; Department of Endocrinology, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, 700000, Viet Nam; Division of Endocrinology, Department of Internal Medicine, Faculty of Medicine, University of Indonesia, Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia; Faculty of Medicine and Surgery, University of Santo Tomas, Manila, 1008, Philippines; Department of Internal Medicine, Calmette Hospital, Phnom Penh, 12201, Cambodia; Department of Endocrinology, University of Medicine 1, Yangon General Hospital, Yangon, 11131, Myanmar; Department of Internal Medicine, R.I.P.A.S. Hospital, Bandar Seri Begawan BA1712, Brunei Darussalam; Department of Internal Medicine, Faculty of Medicine, Universitas Diponegoro, Jawa Tengah, Semarang, 50275, Indonesia; Philippines Center for Diabetes, Thyroid and Endocrine Disorders, St. Luke's Medical Center, Taguig, 1634, Philippines; Health Services Research, Changi General Hospital, Singapore, 529889, Singapore; Department of Medicine, Faculty of Medicine and Health Sciences, University Tunku Abdul Rahman, Kuala Lumpur, 53300, Malaysia; Gleneagles Medical Centre, Singapore, 258500, Singapore; Department of Medicine, Division of Endocrinology, National University Health System, Singapore, 119228, Singapore; Department of Endocrinology, Changi General Hospital, Singapore, 529889, Singapore; Duke National University of Singapore (NUS) Medical School, Singapore, 169857, Singapore	Sukor N., Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, 50300, Malaysia, Department of Medicine, Hospital Canselor Tuanku Muhriz, Kuala Lumpur, 56000, Malaysia; Sunthornyothin S., Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand; Tran T.V., Department of Endocrinology, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, 700000, Viet Nam; Tarigan T.J., Division of Endocrinology, Department of Internal Medicine, Faculty of Medicine, University of Indonesia, Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia; Mercado-Asis L.B., Faculty of Medicine and Surgery, University of Santo Tomas, Manila, 1008, Philippines; Sum S., Department of Internal Medicine, Calmette Hospital, Phnom Penh, 12201, Cambodia; Aung M.W., Department of Endocrinology, University of Medicine 1, Yangon General Hospital, Yangon, 11131, Myanmar; Yong A.M.L., Department of Internal Medicine, R.I.P.A.S. Hospital, Bandar Seri Begawan BA1712, Brunei Darussalam; Tedjo T., Department of Internal Medicine, Faculty of Medicine, Universitas Diponegoro, Jawa Tengah, Semarang, 50275, Indonesia; Villa M., Philippines Center for Diabetes, Thyroid and Endocrine Disorders, St. Luke's Medical Center, Taguig, 1634, Philippines; Khaing N.E.E., Health Services Research, Changi General Hospital, Singapore, 529889, Singapore; Azizan E.A., Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, 50300, Malaysia, Department of Medicine, Hospital Canselor Tuanku Muhriz, Kuala Lumpur, 56000, Malaysia; Kang W.H., Department of Medicine, Faculty of Medicine and Health Sciences, University Tunku Abdul Rahman, Kuala Lumpur, 53300, Malaysia; Lim V., Gleneagles Medical Centre, Singapore, 258500, Singapore; Teo A.E.D., Department of Medicine, Division of Endocrinology, National University Health System, Singapore, 119228, Singapore; Zhang M., Department of Endocrinology, Changi General Hospital, Singapore, 529889, Singapore; Tran H., Department of Endocrinology, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, 700000, Viet Nam; Puar T.H., Department of Endocrinology, Changi General Hospital, Singapore, 529889, Singapore, Duke National University of Singapore (NUS) Medical School, Singapore, 169857, Singapore	Context: While guidelines have been formulated for the management of primary aldosteronism (PA), following these recommendations may be challenging in developing countries with limited health care access. Objective: We aimed to assess the availability and affordability of health care resources for managing PA in the Association of Southeast Asian Nations (ASEAN) region, which includes low-middle-income countries. Methods: We instituted a questionnaire-based survey to specialists managing PA, assessing the availability and affordability of investigations and treatment. Population and income status data were taken from the national census and registries. Results: Nine ASEAN country members (48 respondents) participated. While screening with aldosterone-renin ratio is performed in all countries, confirmatory testing is routinely performed in only 6 countries due to lack of facilities and local assays, and cost constraint. Assays are locally available in only 4 countries, and some centers have a test turnaround time exceeding 3 weeks. In 7 countries (combined population of 442 million), adrenal vein sampling (AVS) is not routinely performed due to insufficient radiological facilities or trained personnel, and cost constraint. Most patients have access to adrenalectomy and medications. In 6 countries, the cost of AVS and adrenalectomy combined is more than 30% of its annual gross domestic product per capita. While most patients had access to spironolactone, it was not universally affordable. Conclusion: Large populations currently do not have access to the health care resources required for the optimal management of PA. Greater efforts are required to improve health care access and affordability. Future guideline revisions for PA may need to consider these limitations. © 2024 The Author(s). Published by Oxford University Press on behalf of the Endocrine Society.	adrenal vein sampling; adrenalectomy; global health; health care economics; health disparities; hyperaldosteronism epidemiology	Adrenalectomy; Asia, Southeastern; Delivery of Health Care; Developing Countries; Disease Management; Health Services Accessibility; Humans; Hyperaldosteronism; Surveys and Questionnaires; aldosterone; captopril; metadrenalin; renin; spironolactone; warfarin; adrenal incidentaloma; adrenalectomy; adult; Article; computer assisted tomography; cost effectiveness analysis; drug cost; female; fluoroscopy; gross national product; health care access; human; hyperaldosteronism; hypertension; hypokalemia; Japan; male; middle aged; practice guideline; prevalence; primary hyperaldosteronism; quality of life; questionnaire; retrospective study; South Africa; Southeast Asia; blood; developing country; diagnosis; disease management; epidemiology; health care delivery; Southeast Asia; therapy	National University of Singapore, NUS; National Medical Research Council, NMRC	Funding text 1: This work was supported by a Global Health Support Award [03/FY2023/P1/17-A32] by SingHealth Duke\u2013NUS Medical School. ; Funding text 2: T.H.P. is supported by the NMRC Transition Award, Singapore. The other authors have nothing to disclose.	Endocrine Society	0021972X		38261997	Article	Q1	1776	1607	View
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117	Amalia M.; Saputri F.C.; Sauriasari R.; Widyantoro B.	Amalia, Muttia (57201697619); Saputri, Fadlina Chany (45561842900); Sauriasari, Rani (16246507200); Widyantoro, Bambang (35286148600)	57201697619; 45561842900; 16246507200; 35286148600	Cholesterol low density lipoprotein associations with complete blood count parameters in atherosclerotic cardiovascular disease patients	2024	AIP Conference Proceedings	3155	1	30007				0	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85196498049&doi=10.1063%2f5.0218103&partnerID=40&md5=d5db89cbf03fdeda55e3adcd862fe364	Doctoral Program, Department of Pharmacology, Faculty of Pharmacy, Universitas Indonesia, Depok, 16424, Indonesia; Department of Pharmacology, Faculty of Pharmacy, Universitas Indonesia, Depok, 16424, Indonesia; Department of Clinical Pharmacy, Faculty of Pharmacy, Universitas Indonesia, Depok, 16424, Indonesia; Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia - National Cardiovascular Center, Harapan Kita, Jakarta, 11420, Indonesia	Amalia M., Doctoral Program, Department of Pharmacology, Faculty of Pharmacy, Universitas Indonesia, Depok, 16424, Indonesia; Saputri F.C., Department of Pharmacology, Faculty of Pharmacy, Universitas Indonesia, Depok, 16424, Indonesia; Sauriasari R., Department of Clinical Pharmacy, Faculty of Pharmacy, Universitas Indonesia, Depok, 16424, Indonesia; Widyantoro B., Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia - National Cardiovascular Center, Harapan Kita, Jakarta, 11420, Indonesia	Cholesterol low density lipoprotein (LDL) is strongly associated with the development of atherosclerotic vascular disease (ASCVD). The objective of this study is to assess the relationships between cholesterol LDL and complete blood count (CBC) in ASCVD patients. This cross-sectional study was conducted at the National Cardiovascular Center Harapan Kita Jakarta. A total of 75 ASCVD patients from outpatient and emergency room departments were included in this study. The Chi-square test and the regression logistic analysis test were used to assess the relationships between cholesterol LDL and CBC. In this study, LDL level was found to be associated with the levels of leucocyte, percentage of eosinophil, percentage of lymphocyte, and absolute monocyte level. Lower eosinophil and lymphocyte levels were associated with increased LDL level. Regression logistic analysis revealed that the percentage of eosinophil (95%CI, 1.20 - 8.98; p value=0.02) and absolute monocyte (95%CI, 0.11 - 0.97; p value=0.04) were significant predictors of higher LDL levels in ASCVD. Increased inflammation due to elevated LDL may have resulted in circulating blood count alterations. Leucocytes and their differential count may aid in determining chronic inflammation and the progression of ASCVD. © 2024 Author(s).					American Institute of Physics	0094243X			Conference paper	-	164	21059	View
213	Ardianov M.F.; Prabowo Y.; Supriadi S.; Mathar P.R.; Kamal A.F.	Ardianov, Mohamad Fadhil (57208439269); Prabowo, Yogi (56682042400); Supriadi, Sugeng (16040272500); Mathar, Pelangi Raihan (58951894800); Kamal, Achmad Fauzi (56648996700)	57208439269; 56682042400; 16040272500; 58951894800; 56648996700	Virtual Three-Dimensional Kinematics Comparison between Normal Healthy Knee and Tumor-Suffered Knee Post Resection with Mega Prosthesis Reconstructed	2024	AIP Conference Proceedings	3080	1	110003				0	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85188436023&doi=10.1063%2f5.0199160&partnerID=40&md5=94a825d7966b21a34952c23272fa86ff	Department of Mechanical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia; Department of Orthopedic and Traumatology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jl. Salemba Raya No 6, Jakarta, 10430, Indonesia; Research Center for Biomedical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia	Ardianov M.F., Department of Mechanical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia; Prabowo Y., Department of Orthopedic and Traumatology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jl. Salemba Raya No 6, Jakarta, 10430, Indonesia; Supriadi S., Department of Mechanical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia, Research Center for Biomedical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia; Mathar P.R., Department of Mechanical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia; Kamal A.F., Department of Orthopedic and Traumatology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jl. Salemba Raya No 6, Jakarta, 10430, Indonesia	In this study, two novel designs of Modular Mega prosthesis (MDF 1 and MDF 2) are generated with different geometries and dimensions, with a reference to a normal knee Modular Prosthesis emerging as one of the most promising alternatives to replace the outdated amputation procedures for bone cancer treatment. To obtain a prosthesis with full flexion ability, a better understanding of normal and healthy knees is needed. To replicate knee movements, 3–axis simulations to acquire interference between femoral condyles and the tibial base is applied to both designs and normal knee to better compare the range of movements. Volume interference as an indicator of high - flexion in knee rotation movements is established. The result showed that MDF 2 can give a superior result of flexion-extension rotations compared to normal knees and MDF 1. The range of movement in internal-external and varus-valgus rotations of normal knees is still higher than both MDF 1 and MDF 2, although the results of movement for both novel designs are not too distinctive. The simulations in this study showed that both designs, MDF 1 and MDF 2 have great potential as a solution after limb-salvage resection. © 2024 American Institute of Physics Inc.. All rights reserved.	Interference femoral condyles-tibial plateau; Modular mega prosthesis distal femur; Osteosarcoma				American Institute of Physics	0094243X			Conference paper	-	164	21059	View
244	Arsianti A.; Bahtiar A.; Azizah N.N.; Fajrin A.M.; Nadapdap L.D.; Ardan A.R.; Ilham A.F.; Liwang F.	Arsianti, Ade (36124567000); Bahtiar, Anton (35365874400); Azizah, Norma Nur (57191927056); Fajrin, Ajeng Megawati (58971503200); Nadapdap, Lince Dameria (57215589740); Ardan, Aulia Rahman (58951222900); Ilham, Ahmad Fadhil (59211476900); Liwang, Ferry (58951887200)	36124567000; 35365874400; 57191927056; 58971503200; 57215589740; 58951222900; 59211476900; 58951887200	In Vitro Study of Alkyl Gallates as a Growth Inhibitor of Cervical HeLa Cancer Cells	2024	AIP Conference Proceedings	3080	1	90004				0	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85188455774&doi=10.1063%2f5.0200800&partnerID=40&md5=f7c8578fe34ed7f901ea6c7260f5bfa6	Department of Medical Chemistry, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no 6, Jakarta, 10430, Indonesia; Drug Development Research Center, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no 6, Jakarta, 10430, Indonesia; Department of Pharmacology, Faculty of Pharmacy, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia; Medical student of Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no 6, Jakarta, 10430, Indonesia	Arsianti A., Department of Medical Chemistry, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no 6, Jakarta, 10430, Indonesia, Drug Development Research Center, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no 6, Jakarta, 10430, Indonesia; Bahtiar A., Department of Pharmacology, Faculty of Pharmacy, Universitas Indonesia, Kampus UI Depok, West Java, 16424, Indonesia; Azizah N.N., Drug Development Research Center, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no 6, Jakarta, 10430, Indonesia; Fajrin A.M., Department of Medical Chemistry, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no 6, Jakarta, 10430, Indonesia; Nadapdap L.D., Drug Development Research Center, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no 6, Jakarta, 10430, Indonesia; Ardan A.R., Medical student of Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no 6, Jakarta, 10430, Indonesia; Ilham A.F., Medical student of Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no 6, Jakarta, 10430, Indonesia; Liwang F., Medical student of Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no 6, Jakarta, 10430, Indonesia	Cervical cancer is the third most common cancer in women and the fifth most common in the world. In Indonesia, the prevalence of cervical cancer is 12.8 out of 100,000 women in 2010, in which become the second most frequent cancer. Current treatments of cervical cancer are surgery, radiation therapy, chemoradiation, or combination therapy. However, the high rate of complications and severe side effects of those therapies indicating the need for the new anti-cervical cancer agent. Gallic acid is known to have potential anticancer effects. Structure modification of gallic acid into its derivatives of alkyl gallates are expected to increase the hydrophobicity of alkyl gallates which led to the improvement of its anticancer activity due to its ability to penetrate cancer cell membrane easily. In this work, we conducted in vitro study of ten synthesized alkyl gallates (methyl gallate, ethyl gallate, propyl gallate, butyl gallate, isobutyl gallate, t-butyl gallate, amyl gallate, isoamyl gallate, heptyl gallate and octyl gallate) against HeLa cervical cancer cells by MTS assay. In vitro cytotoxic activity of alkyl gallates on HeLa cells are expressed in median inhibitory activity (IC50) value. The results showed that heptyl gallate and octyl gallate had the strong cytotoxicity against cervical HeLa cells with IC50 value of 12.32 µg/ml and 51.98 µg/ml, respectively. This result suggests that heptyl gallate and octyl gallate are promising candidates for the new anti-cervical cancer agents. © 2024 American Institute of Physics Inc.. All rights reserved.	Alkyl gallate; cytotoxicity; HeLa cells; in vitro study; MTT assay				American Institute of Physics	0094243X			Conference paper	-	164	21059	View
248	Sinaga G.H.P.; Susanto J.E.; Harlena F.A.K.; Oktavianti S.; Putri R.A.; Yusuf P.A.; Priyono H.	Sinaga, Gideon Hot Partogi (58951062600); Susanto, Johannes Elia (58951227200); Harlena, Filza Amara Kamila (58951062700); Oktavianti, Sakina (58952060100); Putri, Rizki Amalia (57201352861); Yusuf, Prasandhya Astagiri (57192156597); Priyono, Harim (57201550021)	58951062600; 58951227200; 58951062700; 58952060100; 57201352861; 57192156597; 57201550021	Cochlear Implant Performance in Children Deafened by Torch Infection: Scoping Review	2024	AIP Conference Proceedings	3080	1	110001				0	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85188440578&doi=10.1063%2f5.0203457&partnerID=40&md5=68454ed4affba11fad2d5195aab4a256	Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Jakarta, 10430, Indonesia; Medical Technology IMERI, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Jakarta, 10430, Indonesia; Department of Otorhinolaryngology, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Jakarta, 10430, Indonesia	Sinaga G.H.P., Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Jakarta, 10430, Indonesia; Susanto J.E., Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Jakarta, 10430, Indonesia; Harlena F.A.K., Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Jakarta, 10430, Indonesia; Oktavianti S., Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Jakarta, 10430, Indonesia; Putri R.A., Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Jakarta, 10430, Indonesia; Yusuf P.A., Medical Technology IMERI, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Jakarta, 10430, Indonesia; Priyono H., Department of Otorhinolaryngology, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Jakarta, 10430, Indonesia	TORCH infection is described as perinatal infections caused by toxoplasma (To), rubella (R), cytomegalovirus (C), and herpes simplex virus (HSV). Sensorineural hearing loss (SNHL) is the most prevalent postnatal symptom of TORCH infection and may progress to severe and profound SNHL, in which cochlear implant (CI) may be considered. This scoping review will map data on cochlear implantation performance in TORCH-deafened children. Twenty-six articles were reviewed. Most of the studies included (61.5%, n=16) were CMV studies, implying that CMV infection was still the primary etiology for sensorineural hearing loss associated with TORCH infection syndrome. CI is a viable option in the treatment of congenital cytomegalovirus (cCMV), leading to improvements in hearing and language. However, when compared to Cx26 mutation as control, poorer performance was reported for cCMV. CI is also recommended for congenital rubella due to increased speech production, which results in a higher quality of life and the ability to attend regular school. CI was associated with several positive outcomes in toxoplasmosis, including age-appropriate speech perception and social-emotional development. These positive outcomes, however, are only possible with adequate environmental and parental support. No research regarding CI outcomes on patients of hearing loss for specific HSV infection. Nevertheless, CI was recommended for its rehabilitative outcomes. Being one of the first reviews in this context, CI is recommended especially if it is done as early as possible. Nevertheless, prevention measures such as TORCH infection screening and ABR testing are required, particularly in low-and-middle-income countries. © 2024 American Institute of Physics Inc.. All rights reserved.	auditory performance; cochlear implant; congenital sensorineural hearing loss; TORCH infection				American Institute of Physics	0094243X			Conference paper	-	164	21059	View
250	Hansur L.; Louisa M.; Ernawaty B.; Wuyung P.E.; Zaini J.; Fadillah F.; Wibowo H.	Hansur, Lismayana (57296411600); Louisa, Melva (41461551400); Ernawaty, Beti (58952234700); Wuyung, Puspita Eka (57192889605); Zaini, Jamal (57221833355); Fadillah, Fadillah (57879623800); Wibowo, Heri (57217690943)	57296411600; 41461551400; 58952234700; 57192889605; 57221833355; 57879623800; 57217690943	Histopathology Assay of The Lung After Intratracheal Injection of SARS-CoV-2 Spike Protein Recombinant in Mice: A Preliminary Study	2024	AIP Conference Proceedings	3080	1	90002				0	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85188444419&doi=10.1063%2f5.0199399&partnerID=40&md5=78ce8d24493efd2608b2df3f1c67f6bb	Faculty of Medicine and Health Sciences, Universitas Muhammadiyah Makassar, Jl. Sultan Alauddin No. 259, Gn. Sari, Kec. Rappocini, South Sulawesi, Makassar, 90221, Indonesia; Department of Pharmacology & Therapeutic, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no 6, Jakarta, 10430, Indonesia; Department of Microbiology, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no 6, Jakarta, 10430, Indonesia; Department of Pathological Anatomy, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no 6, Jakarta, 10430, Indonesia; Animal Research Facility, Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no 6, Jakarta, 10430, Indonesia; Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no 6, Jakarta, 10430, Indonesia; Department of Medical Chemistry, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no 6, Jakarta, 10430, Indonesia; Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no 6, Jakarta, 10430, Indonesia; Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no 6, Jakarta, 10430, Indonesia	Hansur L., Faculty of Medicine and Health Sciences, Universitas Muhammadiyah Makassar, Jl. Sultan Alauddin No. 259, Gn. Sari, Kec. Rappocini, South Sulawesi, Makassar, 90221, Indonesia; Louisa M., Department of Pharmacology & Therapeutic, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no 6, Jakarta, 10430, Indonesia; Ernawaty B., Department of Microbiology, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no 6, Jakarta, 10430, Indonesia; Wuyung P.E., Department of Pathological Anatomy, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no 6, Jakarta, 10430, Indonesia, Animal Research Facility, Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no 6, Jakarta, 10430, Indonesia; Zaini J., Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no 6, Jakarta, 10430, Indonesia; Fadillah F., Department of Medical Chemistry, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no 6, Jakarta, 10430, Indonesia, Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no 6, Jakarta, 10430, Indonesia; Wibowo H., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no 6, Jakarta, 10430, Indonesia	COVID-19 can cause ARDS, characterized by Diffuse alveolar Damage (DAD) generated by cell death, surfactants, and proteins to the alveolar. When the hyaline membrane accumulates or thickens, oxygen exchange in the alveoli is disrupted. Recent research employing animal model mice has been designed and carried out on various methods that could be used to investigate the mechanisms of inflammation and infection in COVID-19 disease. In this study, we injected SARS-CoV-2 spike recombinant protein into the trachea to make an animal model for studying DAD and infiltration with a histological assay. Methods: To initiate mouse models, an incision is made in above the trachea, the muscles and glands above the trachea are moved. A 26-gauge needle delivered 15 µg of SARS-CoV-2 recombinant spike protein (SC-2 RSP) in 50 µl saline, followed by a 100 µl air injection. The control group was given 50 µl saline intratracheally. Afterward, mice were euthanized with intraperitoneal injections of ketamine and xylazine at 1, 2, and 7-days post-injection (d.p.i.) to harvest the lungs. Hematoxylin & Eosin were used to stain lung tissue for histological examinations. Result: Lung histopathology of BALB/c mice injected with SARS-CoV-2 recombinant spike protein at 1-, 2-, and 7-days post instillation showed mild immune cell infiltration. Cell infiltration was also found at alveolar, perivascular, and peribronchiolar locations compared with untreated mice. According to our study, SARS-CoV-2 recombinant spike protein has been shown to trigger mild lung inflammation in BALB/c mice. © 2024 American Institute of Physics Inc.. All rights reserved.	BALB/c; COVID-19; inflammation; intratracheal; pulmonary disease				American Institute of Physics	0094243X			Conference paper	-	164	21059	View

Publikasi Scopus 2024 per tanggal 31 Juli 2024 (607 artikel)