Per 30 Juni 2024 (499 artikel)

Riset dan Pengabdian Masyarakat Do Research Sosial Service and Innovation

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10	Amalia M.; Saputri F.C.; Sauriasari R.; Widyantoro B.	Amalia, Muttia (57201697619); Saputri, Fadlina Chany (45561842900); Sauriasari, Rani (16246507200); Widyantoro, Bambang (35286148600)	57201697619; 45561842900; 16246507200; 35286148600	Cholesterol low density lipoprotein associations with complete blood count parameters in atherosclerotic cardiovascular disease patients	2024	AIP Conference Proceedings	3155	1	030007				0	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85196498049&doi=10.1063%2f5.0218103&partnerID=40&md5=d5db89cbf03fdeda55e3adcd862fe364	Doctoral Program, Department of Pharmacology, Faculty of Pharmacy, Universitas Indonesia, Depok, 16424, Indonesia; Department of Pharmacology, Faculty of Pharmacy, Universitas Indonesia, Depok, 16424, Indonesia; Department of Clinical Pharmacy, Faculty of Pharmacy, Universitas Indonesia, Depok, 16424, Indonesia; Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia - National Cardiovascular Center, Harapan Kita, Jakarta, 11420, Indonesia	Amalia M., Doctoral Program, Department of Pharmacology, Faculty of Pharmacy, Universitas Indonesia, Depok, 16424, Indonesia; Saputri F.C., Department of Pharmacology, Faculty of Pharmacy, Universitas Indonesia, Depok, 16424, Indonesia; Sauriasari R., Department of Clinical Pharmacy, Faculty of Pharmacy, Universitas Indonesia, Depok, 16424, Indonesia; Widyantoro B., Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia - National Cardiovascular Center, Harapan Kita, Jakarta, 11420, Indonesia	Cholesterol low density lipoprotein (LDL) is strongly associated with the development of atherosclerotic vascular disease (ASCVD). The objective of this study is to assess the relationships between cholesterol LDL and complete blood count (CBC) in ASCVD patients. This cross-sectional study was conducted at the National Cardiovascular Center Harapan Kita Jakarta. A total of 75 ASCVD patients from outpatient and emergency room departments were included in this study. The Chi-square test and the regression logistic analysis test were used to assess the relationships between cholesterol LDL and CBC. In this study, LDL level was found to be associated with the levels of leucocyte, percentage of eosinophil, percentage of lymphocyte, and absolute monocyte level. Lower eosinophil and lymphocyte levels were associated with increased LDL level. Regression logistic analysis revealed that the percentage of eosinophil (95%CI, 1.20 - 8.98; p value=0.02) and absolute monocyte (95%CI, 0.11 - 0.97; p value=0.04) were significant predictors of higher LDL levels in ASCVD. Increased inflammation due to elevated LDL may have resulted in circulating blood count alterations. Leucocytes and their differential count may aid in determining chronic inflammation and the progression of ASCVD. © 2024 Author(s).				American Institute of Physics	0094243X		Conference paper	-	164	21059	View
26	Siregar G.O.; Harianja M.; Adella J.; Krismawati H.; Sundari E.S.; Ataupah M.R.; Laiskodat R.D.; Bøgh C.; Soebono H.; Grijsen M.L.	Siregar, Gladys O. (58876649500); Harianja, Maria (58876435800); Adella, Jacklyn (58994793100); Krismawati, Hana (56572770100); Sundari, Evivana S. (58876435900); Ataupah, Messe R. (58993911900); Laiskodat, Ruth D. (58994354700); Bøgh, Claus (6602120205); Soebono, Hardyanto (6508242918); Grijsen, Marlous L. (25225113700)	58876649500; 58876435800; 58994793100; 56572770100; 58876435900; 58993911900; 58994354700; 6602120205; 6508242918; 25225113700	Leprosy identified in Sumba Island, eastern Indonesia: elimination targets under threat	2024	The Lancet Regional Health - Southeast Asia	26		100409				0	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85190856063&doi=10.1016%2fj.lansea.2024.100409&partnerID=40&md5=4f24b635df4260f90f0d5f674d9efa33	Sumba Foundation, Sumba, Indonesia; Center of Health System and Strategy, Ministry of Health, Jakarta, Indonesia; Department of Dermatology and Venereology, Siloam Hospital, Kupang, Indonesia; Province Health Office, East Nusa Tenggara, Kupang, Indonesia; Department of Dermatology and Venereology, Gadjah Mada University, Yogyakarta, Indonesia; Oxford University Clinical Research Unit Indonesia, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, United Kingdom	Siregar G.O., Sumba Foundation, Sumba, Indonesia; Harianja M., Sumba Foundation, Sumba, Indonesia; Adella J., Sumba Foundation, Sumba, Indonesia; Krismawati H., Center of Health System and Strategy, Ministry of Health, Jakarta, Indonesia; Sundari E.S., Department of Dermatology and Venereology, Siloam Hospital, Kupang, Indonesia; Ataupah M.R., Province Health Office, East Nusa Tenggara, Kupang, Indonesia; Laiskodat R.D., Province Health Office, East Nusa Tenggara, Kupang, Indonesia; Bøgh C., Sumba Foundation, Sumba, Indonesia; Soebono H., Department of Dermatology and Venereology, Gadjah Mada University, Yogyakarta, Indonesia; Grijsen M.L., Oxford University Clinical Research Unit Indonesia, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, United Kingdom	[No abstract available]	awareness; disease burden; disease transmission; health care personnel; human; leprosy; multibacillary leprosy; nerve injury; Note; paucibacillary leprosy; polypharmacy; primary health care; skin care; teledermatology; telemedicine	Wellcome Trust, WT; Sumba Foundation	Funding text 1: The project was financially supported by the Wellcome Trust Africa Asia Programme Vietnam. The authors declare that they have no conflicts of interest. ; Funding text 2: We extend our sincere gratitude to all Sumba Foundation healthcare workers. We wish to acknowledge Ben Naafs for sharing his expertise on leprosy with the clinical team.	Elsevier Ltd	27723682		Note	#N/A	#N/A	#N/A	View
27	Syam A.F.; Utari A.P.; Hasanah N.H.; Rizky A.; Abdullah M.	Syam, Ari Fahrial (8443384400); Utari, Amanda Pitarini (57113585900); Hasanah, Nur Hamidah (58891914600); Rizky, Almaarif (58891914700); Abdullah, Murdani (7103393434)	8443384400; 57113585900; 58891914600; 58891914700; 7103393434	Prevalence and factors associated with celiac disease in high-risk patients with functional gastrointestinal disorders	2024	PLoS ONE	19	6 June	e0297605				0	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85195533614&doi=10.1371%2fjournal.pone.0297605&partnerID=40&md5=d50adb80ad13f0c223cd817e5acdd0c9	Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Syam A.F., Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Utari A.P., Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Hasanah N.H., Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rizky A., Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Abdullah M., Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Celiac disease (CD) is an autoimmune disease of the small intestine triggered by the consumption of gluten-containing foods in individuals with a genetic predisposition. CD was a rare disease until 20 years ago, when the prevalence increased. Currently, there is no data on the prevalence of CD in high-risk adult populations in Indonesia, even though there is a trend of increasing gluten consumption. Therefore, basic research is needed to determine the magnitude of CD in high-risk adult patients in Indonesia while identifying clinical signs/ symptoms, illness history, and lifestyle to determine factors associated with CD in Indonesia. This study is an observational study with a cross-sectional method.Two hundred eighty-three patients who fulfilled the selection and signed the informed consent were recruited from the gastroenterology clinic of Dr. Cipto Mangunkusumo General Hospital. Patients were asked to fill out a celiac disease-related questionnaire and then given anthropometry measurement and blood test for serologic examination with ELISA, consisting of IgA anti-tissue transglutaminase (anti-TTG) and IgG anti-deaminated gliadin peptide (anti-DGP). Statistical analysis was performed using Chi-square and Multivariate logistic regression tests with SPSS software ver. 26. Statistical test differences were considered significant if the p-values were < 0.05. Eight of 283 patients are serologically confirmed with CD (2,83%). On bivariate analysis, the significant variables are age (p < 0,05), constipation (p < 0,05) and history of autoimmune disease (p < 0,05). On multivariate analysis, the only significant variable is the history of autoimmune disease (p < 0,05). This study concluded that the prevalence of CD in high-risk patients with functional gastrointestinal disorder at Dr. Cipto Mangunkusumo Hospital is relatively high (2.83%). CD-associated factors are age, constipation, and history of autoimmune disease in patients. On simultaneous interaction between these factors, autoimmune is the only significant variable associated with CD. © 2024 Syam et al.	Adolescent; Adult; Aged; Celiac Disease; Cross-Sectional Studies; Female; Gastrointestinal Diseases; Humans; Indonesia; Male; Middle Aged; Prevalence; Protein Glutamine gamma Glutamyltransferase 2; Risk Factors; Transglutaminases; Young Adult; gluten; protein glutamine gamma glutamyltransferase; protein glutamine gamma glutamyltransferase 2; abdominal pain; adult; anemia; anthropometry; arthralgia; Article; autoimmune disease; autoimmune hepatitis; autoimmune thyroiditis; bloating; celiac disease; chronic diarrhea; constipation; cross-sectional study; defecation; dermatitis herpetiformis; diarrhea; digestive system function disorder; dizziness; dysmenorrhea; enzyme linked immunosorbent assay; female; food intake; gastroenterology; gastrointestinal symptom; genetic predisposition; headache;			Public Library of Science	19326203	38848393	Article	Q1	885	5108	View
33	Wahyuni L.K.; Nelfidayani N.; Harini M.; Anestherita F.; Wardhani R.K.; Menaldi S.L.; Irawati Y.; Rahayu T.; Andayani G.; Daniel H.; Savitri I.; Hariyanto P.K.Y.; Paramita I.A.	Wahyuni, Luh Karunia (23478815100); Nelfidayani, Nelfidayani (57885297900); Harini, Melinda (57222385190); Anestherita, Fitri (57193003531); Wardhani, Rizky Kusuma (57222033979); Menaldi, Sri Linuwih (57192918198); Irawati, Yunia (57201260313); Rahayu, Tri (57208305374); Andayani, Gitalisa (57219387842); Daniel, Hisar (57316812600); Savitri, Intan (58540127200); Hariyanto, Petrus Kanisius Yogi (58540598000); Paramita, Isabela Andhika (58540939200)	23478815100; 57885297900; 57222385190; 57193003531; 57222033979; 57192918198; 57201260313; 57208305374; 57219387842; 57316812600; 58540127200; 58540598000; 58540939200	The International Classification of Functioning, Disability and Health to map leprosy-related disability in rural and remote areas in Indonesia	2024	PLoS Neglected Tropical Diseases	18	5	e0011539				0	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85195141075&doi=10.1371%2fjournal.pntd.0011539&partnerID=40&md5=1e120a191157885bbc7f958800d23e19	Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Genomik Solidaritas Indonesia (GSI) Laboratory, Jakarta, Indonesia	Wahyuni L.K., Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Nelfidayani N., Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Harini M., Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Anestherita F., Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Wardhani R.K., Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Menaldi S.L., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Irawati Y., Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rahayu T., Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Andayani G., Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Daniel H., Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Savitri I., Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Hariyanto P.K.Y., Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Paramita I.A., Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia, Genomik Solidaritas Indonesia (GSI) Laboratory, Jakarta, Indonesia	The International Classification of Function, Disability, and Health (ICF—WHO, 2001) recognizes several dimensions of disability, such as body structure and function (and impairment thereof), activity (and activity restrictions) and participation (and participation restriction) and their interactions with contextual factor (personal and environmental). In this study, we map and analyse the relationship between the components of ICF in leprosy patients from two rural areas in Indonesia: Lewoleba (East Nusa Tenggara) and Likupang (North Minahasa). This study was part of a community outreach program by the KATAMATAKU team from Universitas Indonesia. The body structure was graded using the WHO hand and feet disability grade and the number of enlarged nerves, while the body function was measured by the Jebsen Taylor Hand Function Test (JTT) and Timed-up and Go (TUG). Activity limitation and participation restriction were measured using the Screening Activity Limitation Safety Awareness (SALSA) Scale and Participation Scale (P-scale), respectively. There were 177 leprosy patients from the two regions and 150 patients with complete data were included in the analysis. We found 82% (95% CI: 75.08%-87.32%) of subjects with multibacillary leprosy, 10.67% (95% CI: 6.67%-16.62%) of subjects with grade 2 WHO hand disability, and 9.33% (95% CI: 5.64%-15.06%) of subjects with grade 2 WHO foot disability. Assessment using the SALSA Scale showed 29.33% of subjects with limitation activity and 11.33% with participation restriction. Age was shown to have positive correlations with SALSA, JTT, and TUG. Inter-dimensional analysis showed that the SALSA scale had significant positive correlations with the number of nerve enlargements, P-scale, JTT, and TUG. SALSA scores of grade 2 WHO hand and foot disability were also significantly higher than grades 1 and 0. The participation scale also had a positive correlation with JTT but not TUG. Hand disability seemed to affect societal participation while foot did not. We used the ICF to describe and analyse dimensions of leprosy-related disability in Indonesia. © 2024 Wahyuni et al.	Activities of Daily Living; Adolescent; Adult; Aged; Disability Evaluation; Disabled Persons; Female; Humans; Indonesia; International Classification of Functioning, Disability and Health; Leprosy; Male; Middle Aged; Rural Population; Young Adult; adult; analysis; Article; bivariate analysis; consultation; correlation coefficient; cross-sectional study; demographics; disability; environmental factor; female; foot; function test; hand; hand function; human; Indonesia; International Classification of Functioning, Disability and Health; Kruskal Wallis test; leprosy; logistic regression analysis; male; middle school; multibacillary leprosy; paucibacillary leprosy; physical disease by body function; physical examination; primary education; rank sum test; rural area; secondary education; survivo	Direktorat Riset and Pengembangan, Universitas Indonesia, DRPM UI, (NKB1402/UN2, RST/HKP.05.00/2022); Direktorat Riset and Pengembangan, Universitas Indonesia, DRPM UI	This study was funded by grant from Directorate of Research and Development, Universitas Indonesia under International-Indexed Publication Grant (PUTI) 2022 (Grant No: NKB1402/UN2.RST/HKP.05.00/2022), with the recipient of our author LKW. Funder data could be accessed from https://ppm.ui.ac.id. The funders had no role in study design, data collection and analysis, decision to publish, or preparati	Public Library of Science	19352727	38771890	Article	Q1	1298	2726	View
35	Hardiany N.S.; Dewi P.K.K.; Dewi S.; Tejo B.A.	Hardiany, Novi Silvia (57192910605); Dewi, Putri Krishna Kumara (58795085300); Dewi, Syarifah (57192904541); Tejo, Bimo A. (6506268507)	57192910605; 58795085300; 57192904541; 6506268507	Exploration of neuroprotective effect from Coriandrum sativum L. ethanolic seeds extracts on brain of obese rats	2024	Scientific Reports	14	1	603				0	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85181517263&doi=10.1038%2fs41598-024-51221-5&partnerID=40&md5=8cb2d2f97417718e92613268842c4aa6	Department of Biochemistry and Molecular Biology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Center of Hypoxia and Oxidative Stress Studies, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Master Program in Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Medical Biochemistry Division, Department of Biomedical Science, Faculty of Medicine, Universitas Pendidikan Ganesha, Bali, 81116, Indonesia; Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, Serdang, 43400, Malaysia	Hardiany N.S., Department of Biochemistry and Molecular Biology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Center of Hypoxia and Oxidative Stress Studies, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Dewi P.K.K., Master Program in Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Medical Biochemistry Division, Department of Biomedical Science, Faculty of Medicine, Universitas Pendidikan Ganesha, Bali, 81116, Indonesia; Dewi S., Department of Biochemistry and Molecular Biology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Center of Hypoxia and Oxidative Stress Studies, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Tejo B.A., Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, Serdang, 43400, Malaysia	In this study, the potential neuroprotective ability of coriander seeds (Coriandrum sativum L.) ethanolic extract (CSES) as a neuroprotectant agent in the brains of high-fat diet-induced obese rats was analyzed. The study investigated how CSES impacts oxidative stress markers (i.e., malondialdehyde/MDA, glutathione/GSH and catalase), inflammation marker (i.e., Interleukin-6/IL-6), cellular senescence markers (i.e., senescence-associated β-galactoside/SA-β-Gal activity and p16), brain damage marker (i.e., Neuron-specific Enolase/NSE), and neurogenesis markers (i.e., mature Brain-derived Neurotropic Factor/BDNF, pro-BDNF, and mature/pro-BDNF ratio). Male adult Wistar rats were fed a high-fat diet and given CSES once daily, at 100 mg/kg body weight, for 12 weeks. CSES significantly reduced MDA concentration (p = < 0.001), SA-β-Gal activity (p = 0.010), and increased GSH concentration (p = 0.047) in the brain of obese rats; however, the decrease of IL-6, NSE, and p16 as well as the increase of catalase specific activity and BDNF expression were not significant. Moreover, the mature/pro-BDNF ratio was significantly higher in the brains of non-obese rats, both given the control diet and the high-fat diet compared to the control. Our results suggest that obese rats benefited from consuming CSES, showing improved oxidative stress levels, reduced cellular senescence and increased endogenous antioxidants, making CSES a potential neuroprotective agent. © 2024, The Author(s).	Animals; Brain; Brain-Derived Neurotrophic Factor; Catalase; Coriandrum; Ethanol; Glutathione; Interleukin-6; Male; Neuroprotective Agents; Obesity; Rats; Rats, Wistar; Seeds; alcohol; brain derived neurotrophic factor; catalase; glutathione; interleukin 6; neuroprotective agent; animal; brain; Coriandrum; male; obesity; plant seed; rat; Wistar rat	HIBAH PUTI Universitas Indonesia 2023, (NKB-392/UN2.RST/HKP.05.00/2023)	This research received funding from HIBAH PUTI Universitas Indonesia 2023 (grant number: NKB-392/UN2.RST/HKP.05.00/2023).	Nature Research	20452322	38182767	Article	Q1	973	4401	View
45	Widodo D.W.; Zizlavsky S.	Widodo, Dini Widiarni (56644646600); Zizlavsky, Semiramis (57195721920)	56644646600; 57195721920	Correlation of Grading and Number of Ear Subunits With Auditory Brainstem Response Findings in Children With Microtia	2024	American journal of audiology	33	2		503	509	6	0	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85195228893&doi=10.1044%2f2024_AJA-23-00162&partnerID=40&md5=eb3bc6e67c83e792538fd55464696ebd	Department of Ear Nose Throat-Head Neck Surgery, Faculty of Medicine, University of Indonesia - Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia	Widodo D.W., Department of Ear Nose Throat-Head Neck Surgery, Faculty of Medicine, University of Indonesia - Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Zizlavsky S., Department of Ear Nose Throat-Head Neck Surgery, Faculty of Medicine, University of Indonesia - Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia	PURPOSE: The association between microtia severity and hearing function has been thoroughly investigated. This study examined the relationship between microtia grade, number of ear subunits (i.e., helix, antihelix, scapha, triangularis fossa, concha, lobule, tragus, and antitragus) with auditory brainstem response (ABR) findings in children with microtia. STUDY DESIGN: A retrospective chart review was employed in this study. METHOD: We analyzed the ABR test results and photographs of 22 children with 30 microtia ears at Dr. Cipto Mangunkusumo National Hospital, Jakarta. The ABR test results were acquired using click (air conduction only) and 500-Hz tone burst stimuli (air- and bone-conduction). Ear photographs were overlaid with a template of a normal ear to determine the number of ear subunits present and the subsequent microtia grade. Number of ear subunits and ABR results were analyzed using the chi-square, Mann-Whitney U, and Spearman's correlation tests. RESULTS: ABR thresholds for click and 500-Hz tone bursts air-conduction were significantly poorer for ears with a subunit < 5 compared to ears with a subunit ≥ 5. No significant difference was observed in 500 Hz bone-conduction ABR thresholds between these groups. Correlation analysis showed a significant negative correlation between increased ear subunits and click ABR thresholds. No significant correlation was found between ear subunits and 500-Hz air- and bone-conduction ABR thresholds. CONCLUSIONS: A higher number of ear subunits are associated with a lower hearing threshold, as assessed using ABR with click stimuli. Therefore, the number of ear subunits and microtia grades can be used to examine the hearing level thresholds in infants and children with microtia. SUPPLEMENTAL MATERIAL: https://doi.org/10.23641/asha.25669440.	Adolescent; Auditory Threshold; Child; Child, Preschool; Congenital Microtia; Ear; Evoked Potentials, Auditory, Brain Stem; Female; Humans; Male; Retrospective Studies; Severity of Illness Index; adolescent; auditory threshold; child; ear; evoked brain stem auditory response; female; human; male; microtia; pathophysiology; physiology; preschool child; retrospective study; severity of illness index				15589137	38668691	Article	Q2	677	7414	View
68	Karyanti M.R.; Uiterwaal C.S.P.M.; Hadinegoro S.R.; Widyahening I.S.; Saldi S.R.F.; Heesterbeek J.A.P.H.; Hoes A.W.; Bruijning-Verhagen P.	Karyanti, Mulya Rahma (56290680800); Uiterwaal, Cuno S P M (59148037600); Hadinegoro, Sri Rezeki (56893685800); Widyahening, Indah Suci (54893154400); Saldi, Siti Rizny F (55201904000); Heesterbeek, J A P Hans (59134733500); Hoes, Arno W. (35370614300); Bruijning-Verhagen, Patricia (55175644800)	56290680800; 59148037600; 56893685800; 54893154400; 55201904000; 59134733500; 35370614300; 55175644800	The Value of Warning Signs From the WHO 2009 Dengue Classification in Detecting Severe Dengue in Children	2024	The Pediatric infectious disease journal	43	7		630	634	4	0	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85196767536&doi=10.1097%2fINF.0000000000004326&partnerID=40&md5=04c0ef35f4c83ec1bb4da39449b609c4	From the Department of Child Health, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht and Utrecht University, Utrecht, Netherlands; Department of Community Medicine, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Clinical Epidemiology and Evidence-Based Medicine Unit, Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Population Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands	Karyanti M.R., From the Department of Child Health, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht and Utrecht University, Utrecht, Netherlands; Uiterwaal C.S.P.M., Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht and Utrecht University, Utrecht, Netherlands; Hadinegoro S.R., From the Department of Child Health, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Widyahening I.S., Department of Community Medicine, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Saldi S.R.F., Clinical Epidemiology and Evidence-Based Medicine Unit, Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Heesterbeek J.A.P.H., Department of Population Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands; Hoes A.W., Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht and Utrecht University, Utrecht, Netherlands; Bruijning-Verhagen P., Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht and Utrecht University, Utrecht, Netherlands	BACKGROUND: World Health Organization proposed 7 warning signs to identify the risk of severe dengue in 2009. This study aimed to evaluate the value of these warning signs in detecting severe dengue in children. MATERIAL AND METHODS: A cross-sectional study was conducted utilizing data of children with clinical dengue infection obtained from medical records between January 2009 and December 2018 in Jakarta. Children with confirmed dengue were analyzed and stratified into 3 age groups: infants less than 1 year old, children 1-14 years and adolescents 15-18 years of age. Positive predictive value, negative predictive value (NPV), sensitivity and specificity of each warning sign present or absent on admission in detecting severe dengue were computed. RESULTS: Six hundred ninety-nine children with clinical dengue infection were enrolled, among whom 614 (87.8%) had confirmed dengue infection, either by antigen or antibody serological tests. Severe dengue occurred in 211/614 (34.4%) cases. In infants, important warning signs on admission to detect or exclude severe dengue were liver enlargement (NPV 80.8%) and clinical fluid accumulation (NPV 75%). In children and adolescents, warning sign with highest NPV (in children 76.6% and in adolescents 91.9%) was increase in hematocrit concurrent with a rapid decrease in platelet count. Other warning signs with high NPV values in children were abdominal pain (72%), vomiting (70%), clinical fluid accumulation (69.3%), and in adolescents' abdominal pain (80.7%), vomiting (75.7%), clinical fluid accumulation (82.7%). NPVs increase with more than 1 warning sign in all age groups. CONCLUSION: In infants, liver enlargement or clinical fluid accumulation are important warning signs for severe dengue, when both are absent, severe dengue is unlikely. In older children and adolescents, an increase in hematocrit with the concurrent rapid decrease in platelet count is most discriminative; followed by the absence of abdominal pain, vomiting or fluid accumulation are unlikely severe dengue. Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc.	Adolescent; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Infant; Male; Sensitivity and Specificity; Severe Dengue; World Health Organization; adolescent; child; cross-sectional study; diagnosis; female; human; infant; male; preschool child; sensitivity and specificity; severe dengue; World Health Organization				15320987	38652064	Article	#N/A	#N/A	#N/A	View
92	Corduff N.; Park J.-Y.; Calderon P.E.; Choi H.; Dingley M.; Ho W.W.S.; Martin M.U.; Suseno L.S.; Tseng F.-W.; Vachiramon V.; Wanitphakdeedecha R.; Yu J.N.T.	Corduff, Niamh (7801565751); Park, Je-Young (57113852900); Calderon, Pacifico E. (57777897000); Choi, Hosung (57766086300); Dingley, Mary (57778575200); Ho, Wilson W.S. (56909376500); Martin, Michael U. (57777897100); Suseno, Lis S. (57202804092); Tseng, Fang-Wen (59183482500); Vachiramon, Vasanop (24330191600); Wanitphakdeedecha, Rungsima (14040758200); Yu, Jonathan N.T. (57129203200)	7801565751; 57113852900; 57777897000; 57766086300; 57778575200; 56909376500; 57777897100; 57202804092; 59183482500; 24330191600; 14040758200; 57129203200	Real-world Implications of Botulinum Neurotoxin A Immunoresistance for Consumers and Aesthetic Practitioners: Insights from ASCEND Multidisciplinary Panel	2024	Plastic and Reconstructive Surgery - Global Open	12	6	e5892				0	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85196648000&doi=10.1097%2fGOX.0000000000005892&partnerID=40&md5=2df70e082bbbfdbd93a620a1832ae198	Geelong, VIC, Australia; Apkoo-Jung Oracle Dermatology Clinic, Seoul, South Korea; Department of Professionalism, Medical Ethics and Humanities, College of Medicine, and Clinical Ethics Services, St. Luke’s Medical Center, Quezon City, Philippines; Piena Clinic, Seoul, South Korea; The Cosmetic Medicine Centre, Toowong, QLD, Australia; The Specialists:, Lasers, Aesthetics and Plastic Surgery, Central, Hong Kong; Lower Saxony, Springe, Germany; Division of Cosmetic Dermatology, Department of Dermatology and Venereology, Faculty of Medicine, University of Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Taoyuan Milano Aesthetic Clinic, Taoyuan City, Taiwan; Division of Dermatology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand; JY Dermatology and Aesthetic Center, Metro Manila, Philippines	Corduff N., Geelong, VIC, Australia; Park J.-Y., Apkoo-Jung Oracle Dermatology Clinic, Seoul, South Korea; Calderon P.E., Department of Professionalism, Medical Ethics and Humanities, College of Medicine, and Clinical Ethics Services, St. Luke’s Medical Center, Quezon City, Philippines; Choi H., Piena Clinic, Seoul, South Korea; Dingley M., The Cosmetic Medicine Centre, Toowong, QLD, Australia; Ho W.W.S., The Specialists:, Lasers, Aesthetics and Plastic Surgery, Central, Hong Kong; Martin M.U., Lower Saxony, Springe, Germany; Suseno L.S., Division of Cosmetic Dermatology, Department of Dermatology and Venereology, Faculty of Medicine, University of Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Tseng F.-W., Taoyuan Milano Aesthetic Clinic, Taoyuan City, Taiwan; Vachiramon V., Division of Dermatology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; Wanitphakdeedecha R., Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand; Yu J.N.T., JY Dermatology and Aesthetic Center, Metro Manila, Philippines	Background: As long-term, regular aesthetic botulinum neurotoxin A (BoNT-A) use becomes more commonplace, it is vital to understand real-world risk factors and impact of BoNT-A immunoresistance. The first Aesthetic Council on Ethical Use of Neurotoxin Delivery panel discussed issues relating to BoNT-A immunoresistance from the health care professionals’ (HCPs’) perspective. Understanding the implications of BoNT-A immunoresistance from the aesthetic patient’s viewpoint allows HCPs to better support patients throughout their aesthetic treatment journey. Methods: A real-world consumer study surveyed 363 experienced aesthetic BoNT-A recipients across six Asia-Pacific territories. The survey mapped participants’ BoNT-A aesthetic treatment journey and characterized awareness and attitudes relating to BoNT-A immunoresistance and treatment implications. At the second Aesthetic Council on Ethical use of Neurotoxin Delivery meeting, panelists discussed survey findings and developed consensus statements relating to the impact of BoNT-A immunoresistance on the aesthetic treatment journey. Results: Aesthetic BoNT-A patients’ depth of knowledge about BoNT-A immunoresistance remains low, and risk/benefit communications need to be more lay-friendly. The initial consultation is the most important touchpoint for HCPs to raise awareness of BoNT-A immunoresistance as a potential side effect considering increased risk with repeated high-dose treatments. HCPs should be cognizant of differences across BoNT-A formulations due to the presence of certain excipients and pharmacologically unnecessary components that can increase immunogenicity. Standardized screening for clinical signs of secondary nonresponse and a framework for diagnosing and managing immunoresistance-related secondary nonresponse were proposed. Conclusion: These insights can help patients and HCPs make informed treatment decisions to achieve desired aesthetic outcomes while preserving future treatment options with BoNT-A. Copyright © 2024 The Authors.		Merz Aesthetics; Merz Aesthetics, Galderma, and Allergan	Funding text 1: The authors dedicate this work to the memory of Dr. Wilson W. S. Ho, who unexpectedly passed away in January 2024. In addition to being an esteemed colleague and friend, Dr. Ho made important contributions to the field of plastic surgery and aesthetic medicine and was an integral part of this author group\u2019s efforts to contribute to the discourse on evolving and future use of B	Lippincott Williams and Wilkins	21697574		Article	Q2	671	7496	View
99	Tenda E.D.; Henrina J.; Setiadharma A.; Aristy D.J.; Romadhon P.Z.; Thahadian H.F.; Mahdi B.A.; Adhikara I.M.; Marfiani E.; Suryantoro S.D.; Yunus R.E.; Yusuf P.A.	Tenda, Eric Daniel (57189692101); Henrina, Joshua (57218482646); Setiadharma, Andry (58837878100); Aristy, Dahliana Jessica (58837378800); Romadhon, Pradana Zaky (57211318799); Thahadian, Harik Firman (58082324500); Mahdi, Bagus Aulia (57208279588); Adhikara, Imam Manggalya (58082150300); Marfiani, Erika (57218766909); Suryantoro, Satriyo Dwi (57222345502); Yunus, Reyhan Eddy (57215658457); Yusuf, Prasandhya Astagiri (57192156597)	57189692101; 57218482646; 58837878100; 58837378800; 57211318799; 58082324500; 57208279588; 58082150300; 57218766909; 57222345502; 57215658457; 57192156597	Derivation and validation of novel integrated inpatient mortality prediction score for COVID-19 (IMPACT) using clinical, laboratory, and AI—processed radiological parameter upon admission: a multicentre study	2024	Scientific Reports	14	1	2149				2	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85183040813&doi=10.1038%2fs41598-023-50564-9&partnerID=40&md5=993a2db75f9c61381c865251785f80e6	Pulmonology and Critical Care Medicine Division, Department of Internal Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine Universitas Indonesia, Jl. Pangeran Diponegoro No. 71, RW. 5, Kenari, Kec. Senen, Kota Jakarta Pusat, Daerah Khusus Ibukota Jakarta, 10430, Indonesia; Medical Technology Cluster of Indonesian Medical Research Institute (IMERI), Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Hematology and Medical Oncology, Department of Internal Medicine, Universitas Airlangga Academic Hospital, Faculty of Medicine Universitas Airlangga, Surabaya, Indonesia; Pulmonology and Critical Care Medicine Division, Department of Internal Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Dr. Sardjito General Hospital, Yogyakarta, Indonesia; Department of Internal Medicine, Faculty of Medicine Universitas Airlangga, Surabaya, Indonesia; Cardiology Division, Department of Internal Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Dr. Sardjito General Hospital, Yogyakarta, Indonesia; Pulmonology and Critical Care Medicine Division, Department of Internal Medicine, Faculty of Medicine Universitas Airlangga, Universitas Airlangga Academic Hospital, Surabaya, Indonesia; Nephrology Division, Department of Internal Medicine, Faculty of Medicine Universitas Airlangga, Universitas Airlangga Academic Hospital, Surabaya, Indonesia; Department of Radiology, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Medical Physiology and Biophysics, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia	Tenda E.D., Pulmonology and Critical Care Medicine Division, Department of Internal Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine Universitas Indonesia, Jl. Pangeran Diponegoro No. 71, RW. 5, Kenari, Kec. Senen, Kota Jakarta Pusat, Daerah Khusus Ibukota Jakarta, 10430, Indonesia, Medical Technology Cluster of Indonesian Medical Research Institute (IMERI), Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Henrina J., Pulmonology and Critical Care Medicine Division, Department of Internal Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine Universitas Indonesia, Jl. Pangeran Diponegoro No. 71, RW. 5, Kenari, Kec. Senen, Kota Jakarta Pusat, Daerah Khusus Ibukota Jakarta, 10430, Indonesia; Setiadharma A., Pulmonology and Critical Care Medicine Division, Department of Internal Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine Universitas Indonesia, Jl. Pangeran Diponegoro No. 71, RW. 5, Kenari, Kec. Senen, Kota Jakarta Pusat, Daerah Khusus Ibukota Jakarta, 10430, Indonesia; Aristy D.J., Pulmonology and Critical Care Medicine Division, Department of Internal Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine Universitas Indonesia, Jl. Pangeran Diponegoro No. 71, RW. 5, Kenari, Kec. Senen, Kota Jakarta Pusat, Daerah Khusus Ibukota Jakarta, 10430, Indonesia; Romadhon P.Z., Hematology and Medical Oncology, Department of Internal Medicine, Universitas Airlangga Academic Hospital, Faculty of Medicine Universitas Airlangga, Surabaya, Indonesia; Thahadian H.F., Pulmonology and Critical Care Medicine Division, Department of Internal Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Dr. Sardjito General Hospital, Yogyakarta, Indonesia; Mahdi B.A., Department of Internal Medicine, Faculty of Medicine Universitas Airlangga, Surabaya, Indonesia; Adhikara I.M., Cardiology Division, Department of Internal Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Dr. Sardjito General Hospital, Yogyakarta, Indonesia; Marfiani E., Pulmonology and Critical Care Medicine Division, Department of Internal Medicine, Faculty of Medicine Universitas Airlangga, Universitas Airlangga Academic Hospital, Surabaya, Indonesia; Suryantoro S.D., Nephrology Division, Department of Internal Medicine, Faculty of Medicine Universitas Airlangga, Universitas Airlangga Academic Hospital, Surabaya, Indonesia; Yunus R.E., Medical Technology Cluster of Indonesian Medical Research Institute (IMERI), Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Department of Radiology, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Yusuf P.A., Medical Technology Cluster of Indonesian Medical Research Institute (IMERI), Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Department of Medical Physiology and Biophysics, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia	Limited studies explore the use of AI for COVID-19 prognostication. This study investigates the relationship between AI-aided radiographic parameters, clinical and laboratory data, and mortality in hospitalized COVID-19 patients. We conducted a multicentre retrospective study. The derivation and validation cohort comprised of 512 and 137 confirmed COVID-19 patients, respectively. Variable selection for constructing an in-hospital mortality scoring model was performed using the least absolute shrinkage and selection operator, followed by logistic regression. The accuracy of the scoring model was assessed using the area under the receiver operating characteristic curve. The final model included eight variables: anosmia (OR: 0.280; 95%CI 0.095–0.826), dyspnoea (OR: 1.684; 95%CI 1.049–2.705), loss of consciousness (OR: 4.593; 95%CI 1.702–12.396), mean arterial pressure (OR: 0.928; 95%CI 0.900–0.957), peripheral oxygen saturation (OR: 0.981; 95%CI 0.967–0.996), neutrophil % (OR: 1.034; 95%CI 1.013–1.055), serum urea (OR: 1.018; 95%CI 1.010–1.026), affected lung area score (OR: 1.026; 95%CI 1.014–1.038). The Integrated Inpatient Mortality Prediction Score for COVID-19 (IMPACT) demonstrated a predictive value of 0.815 (95% CI 0.774–0.856) in the derivation cohort. Internal validation resulted in an AUROC of 0.770 (95% CI 0.661–0.879). Our study provides valuable evidence of the real-world application of AI in clinical settings. However, it is imperative to conduct prospective validation of our findings, preferably utilizing a control group and extending the application to broader populations. © 2024, The Author(s).	Arterial Pressure; COVID-19; Humans; Inpatients; Logistic Models; Retrospective Studies; ROC Curve; arterial pressure; clinical trial; coronavirus disease 2019; diagnostic imaging; hospital patient; human; multicenter study; receiver operating characteristic; retrospective study; statistical model	Delft Imaging System; Indonesian Collaboration Research Program, (NKB-1061UN2, RST/HKP.05.00/2022); Universitas Indonesia, UI	Funding text 1: The research team received support from the Indonesian Collaboration Research Program Grant NKB-1061UN2.RST/HKP.05.00/2022. Additionally, a joint research arrangement has been signed between Universitas Indonesia, RSPUN dr. Cipto Mangunkusumo Hospital, and Delft Imaging System, outlining the rights and obligations of each party regarding data confidentiality during and after the re	Nature Research	20452322	38272920	Article	Q1	973	4401	View
103	Prasetyono T.O.H.	Prasetyono, Theddeus Octavianus Hari (26646993900)	26646993900	Hand surgery without tourniquet as a model for the development of surgical service innovation for competitive advantage-based service readiness	2024	Medical Journal of Indonesia	33	1		3	8	5	0	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85194368611&doi=10.13181%2fmji.com.247399&partnerID=40&md5=66732f9471870db61dd7973df249d99c	Department of Surgery, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Indonesian Clinical Training and Education Center (ICTEC), Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia	Prasetyono T.O.H., Department of Surgery, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia, Indonesian Clinical Training and Education Center (ICTEC), Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia	[No abstract available]	estrogen receptor; breast augmentation; Doppler flowmetry; follow up; full awake hand surgery; ganglion cyst; general anesthesia; hand injury; hand surgery; health care organization; human; ischemia; medical research; Note; patient safety; regional anesthesia; surgeon; synovium; training; wound healing; wrist ganglion			Faculty of Medicine, Universitas Indonesia	08531773		Note	Q4	165	21041	View

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