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Id	Authors	Full Names	Author S Id	Title	Year	Source Title	Volume	Issue	Page Start	Page End	Page Count	Cited By	Link	Affiliations	Authors With Affiliations	Abstract	Author Keywords	Index Keywords	Funding Details	Funding Text	Publisher	Issn	Pubmed Id	Document Type	Sjr Best Quartile	Sjr	Sjr Rank
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Acta Cardiologica(1)
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365	Kohar K.; Sanjaya I.S.; Amirah S.; Yumnanisha D.A.; Ambari A.M.	Kohar, Kelvin (57536819200); Sanjaya, Indira Saraswati (59092605900); Amirah, Shakira (57782995800); Yumnanisha, Defin Allevia (59092606000); Ambari, Ade Meidian (57189576921)	57536819200; 59092605900; 57782995800; 59092606000; 57189576921	The potential of triglyceride-glucose index in improving the prediction of post-percutaneous coronary intervention clinical outcomes: a systematic review and meta-analysis	2024	Acta Cardiologica						0	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85192539078&doi=10.1080%2f00015385.2024.2349829&partnerID=40&md5=0d3b8aa6dffa89ee2f5e3f8bde27378c	Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Department of Cardiology and Vascular Medicine, National Cardiovascular Center Harapan Kita, Universitas Indonesia, Jakarta, Indonesia	Kohar K., Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Sanjaya I.S., Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Amirah S., Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Yumnanisha D.A., Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Ambari A.M., Faculty of Medicine, University of Indonesia, Jakarta, Indonesia, Department of Cardiology and Vascular Medicine, National Cardiovascular Center Harapan Kita, Universitas Indonesia, Jakarta, Indonesia	Introduction: Despite percutaneous coronary intervention is the current preferred reperfusion modality, the incidence of major adverse cardiovascular events (MACE) is still high. Currently, GRACE score is used for predicting PCI outcomes. The TyG (triglyceride-glucose) index, a potential predictor based on insulin resistance of cardiovascular disease, has not been considered in the GRACE score. Objective: To assess the potential of the TyG index in predicting cardiovascular adverse clinical outcomes in patients undergoing PCI. Method: Following PRISMA guidelines, the authors reviewed literature from five databases. We included studies investigating post-PCI outcomes based on the TyG index level. Effect size was estimated using RevMan to calculate pooled odds ratio and mean difference, and R software to perform diagnostic test accuracy. Results: Overall, 31,671 post-PCI patients with acute coronary syndrome were included in this study. A significant difference in TyG index was found between patients who experienced MACE and those who did not [MD: 0.3 (0.2–0.4), p <.05]. Higher TyG index was strongly correlated with higher MACE [OR: 2.01 (1.45–2.77), p <.05], especially revascularization [OR: 2.40 (1.72–3.36), p <.05], followed by myocardial infarction [OR: 1.80 (2.41–2.86), p <.05], death [OR: 1.36 (0.86–2.15), p =.19], and stroke [OR: 1.09 (0.79–1.50), p =.59]. Tyg Index showed 55% sensitivity, 60% specificity, and 0.612 accuracy. The addition of the TyG index to the GRACE scoring improved the predictive model’s AUC (0.746 vs. 0.809). Conclusion: This systematic review and meta-analysis comprises evidence-based results for the correlation of TyG index and post-PCI outcomes, demonstrating modest sensitivity, specificity, accuracy, and enhanced predictive value of GRACE score. © 2024 Belgian Society of Cardiology.	major adverse cardiovascular effect; percutaneous coronary intervention; prediction model; Triglyceride-glucose index				Taylor and Francis Ltd.	00015385		Article	Q3	355	13556	View
Acta Dermatovenerologica Alpina, Pannonica et Adriatica(1)
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469	Sukma P.M.G.; Menaldi S.L.S.W.; Wibawa L.P.; Yusharyahya S.N.; Isbayuputra M.	Sukma, Putu Martha Gerynda (57575736500); Menaldi, Sri Linuwih SW (57192918198); Wibawa, Larisa Paramitha (57868291800); Yusharyahya, Shannaz Nadia (57211780941); Isbayuputra, Marsen (58089892200)	57575736500; 57192918198; 57868291800; 57211780941; 58089892200	Photoaging assessment by Glogau classification: correlation of dermoscopy findings in the coastal population of Indonesia	2024	Acta Dermatovenerologica Alpina, Pannonica et Adriatica	33	1	1	5	4	0	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85189109334&doi=10.15570%2factaapa.2024.5&partnerID=40&md5=9d3f3283d7cd94cb3b06b9e2dd42f3c8	Department of Dermatology and Venereology, Faculty of Medicine, University of Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Community Medicine, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia	Sukma P.M.G., Department of Dermatology and Venereology, Faculty of Medicine, University of Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Menaldi S.L.S.W., Department of Dermatology and Venereology, Faculty of Medicine, University of Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Wibawa L.P., Department of Dermatology and Venereology, Faculty of Medicine, University of Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Yusharyahya S.N., Department of Dermatology and Venereology, Faculty of Medicine, University of Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Isbayuputra M., Department of Community Medicine, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia	Introduction: To date, there is no gold standard for identifying photoaging. This study investigates the correlation of photoaging profiles based on the Glogau scale and the dermoscopy photoaging scale (DPAS) in a coastal population. Methods: An analytical cross-sectional study was conducted at Cilincing Municipal Health Center in Jakarta in October 2022. Individuals living in the coastal area, 20 years and older, with Fitzpatrick skin types III–V, and with a mean daily sun exposure of ≥ 3 hours were included. The Glogau scale and DPAS were assessed through history taking, physical examination, and dermoscopic examination. A Spearman correlation test was used to assess the correlation between the Glogau scale and DPAS. Results: Thirty individuals with a mean age of 41.5 ± 11.5 years participated in the study. The median Glogau score was 3 (range: 2–4). The mean DPAS score was 28.5 ± 5.6. Lentigo, hypo-hyperpigmented macules, telangiectasia, deep wrinkles, and superficial wrinkles were observed in all subjects. There was a moderate positive correlation between the Glogau scale and DPAS (r = 0.536, p = 0.002). Conclusions: The Glogau scale has a significant correlation with DPAS. DPAS can serve as a reliable, easy, practical, and fast diagnostic tool to assess the severity of aging. © 2024, Slovene Medical Society. All rights reserved.	aging profile; coastal area; correlation; dermoscopy photoaging scale; Glogau scale	Adult; Cross-Sectional Studies; Dermoscopy; Humans; Indonesia; Middle Aged; Skin; Skin Aging; actinic keratosis; adult; Article; clinical examination; cohort analysis; cross-sectional study; dermoscopy photoaging scale; disease assessment; disease classification; epiluminescence microscopy; female; Glogau classification; human; hyperpigmentation; keratosis; lentigo; male; middle aged; occupation; photoaging; physical examination; skin atrophy; skin discoloration; sociodemographics; sun exposure; telangiectasia; wrinkle; cutaneous parameters; epiluminescence microscopy; Indonesia; skin	Universitas Indonesia, UI	This research received a grant with approval number KET-1084/ UN2.F1/ETIK/PPM.00.02/2022 from the University of Indonesia (Publikasi Terindeks Internasional 2022).	Slovene Medical Society	13184458	38532654	Article	#N/A	#N/A	#N/A	View
Acta Medica Indonesiana(8)
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305	Paramitha M.S.; Esa D.F.; Hustrini N.M.; Mulansari N.A.; Hasan I.; Harahap A.S.	Paramitha, Maria Satya (57212562901); Esa, Dekta Filantropi (58782482100); Hustrini, Ni Made (57200424892); Mulansari, Nadia Ayu (36519326000); Hasan, Irsan (12776850800); Harahap, Agnes Stephanie (57218511857)	57212562901; 58782482100; 57200424892; 36519326000; 12776850800; 57218511857	Secondary Polycythemia and Non-Islet Cell Tumor-induced Hypoglycemia in Advanced Hepatocellular Carcinoma: A Case Report	2024	Acta Medica Indonesiana	56	1	93	101	8	0	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85189767843&partnerID=40&md5=2bcd70b3f26cb2eed9ce9237edbed27d	Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Nephrology and Hypertension, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Hematology and Oncology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Hepatobiliary, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Paramitha M.S., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Esa D.F., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Hustrini N.M., Division of Nephrology and Hypertension, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Mulansari N.A., Division of Hematology and Oncology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Hasan I., Division of Hepatobiliary, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Harahap A.S., Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Continuously holding its position as the sixth most common cause of cancer and the third leading cause of cancer death, globally, Hepatocellular Carcinoma (HCC) remains as a healthcare priority. Production of various substances may result into systemic or metabolic complications, often known as paraneoplastic phenomena of HCC. A 56-year-old male with history of untreated chronic hepatitis B arrived with generalized weakness and intermittent headache in the last two days prior to admission. Laboratory findings demonstrated elevated hemoglobin (20.5 g/dl), alpha-fetoprotein (29,845 ng/dl), and d-Dimer (2,120 ng/ml) levels. Hypoglycemia (44 mg/dl) was documented with normal basal insulin level, confirming non-islet cell tumor hypoglycemia. Abdominal multiphasic CT-scan demonstrated a large solid lesion involving the whole right liver lobe, hyper-enhanced at arterial phase and wash-out pattern at venous and delayed phases, with portal vein thrombosis; thus, confirming HCC BCLC C. Further examinations revealed hypercellularity from bone marrow biopsy with the absence of JAK2 mutation. He underwent serial phlebotomy and received 80 mg acetylsalicylic acid orally, as well as cytoreductive agent to reduce the risk of thrombosis. Despite applications of different interventions, control of hypoglycemia could not be achieved without parenteral administration of high dextrose load. He was planned to receive oral multikinase inhibitor, however, he passed away due to severe hospital-acquired pneumonia. Paraneoplastic phenomena are common in HCC. Increased risk of blood hyper-viscosity and thrombosis attributed to polycythemia, as well as medical emergency resulting from hypoglycemia showed that both conditions should not be overlooked since they may worsen the patient’s prognosis. © 2024, Indonesian Society of Internal Medicine. All rights reserved.	Hepatocellular Carcinoma; Non-Islet Cell Tumor-Induced Hypoglycemia; Secondary Erythrocytosis; Secondary Polycythemia	Carcinoma, Hepatocellular; Humans; Hypoglycemia; Liver Neoplasms; Male; Middle Aged; Polycythemia; Thrombosis; case report; complication; human; hypoglycemia; liver cell carcinoma; liver tumor; male; middle aged; pathology; polycythemia; thrombosis			Indonesian Society of Internal Medicine	01259326	38561874	Article	Q3	282	15714	View
318	Darmawan D.; Rengganis I.; Rumende C.M.; Shatri H.; Koesnoe S.; Umbarawan Y.; Putranto R.; Nasution S.A.	Darmawan, Danny (58976408900); Rengganis, Iris (8449988000); Rumende, Cleopas Martin (14325966300); Shatri, Hamzah (28767986500); Koesnoe, Sukamto (26028015000); Umbarawan, Yogi (57196077830); Putranto, Rudi (56074051000); Nasution, Sally Aman (57189373134)	58976408900; 8449988000; 14325966300; 28767986500; 26028015000; 57196077830; 56074051000; 57189373134	Effecti veness and Safety of Nebul i zed Magnesi um as Last Line Treatment in Adults with Acute Asthma Attack: A Systematic Review and Meta-Analysis	2024	Acta Medica Indonesiana	56	1	3	12	9	0	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85189770601&partnerID=40&md5=6acc1048d420192d41767ce80e328d50	Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Allergy and Immunology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Respirology and Critical Illness, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Psychosomatic and Palliative Medicine, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo, Jakarta, Indonesia; Division of Cardiology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo, Jakarta, Indonesia	Darmawan D., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rengganis I., Division of Allergy and Immunology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rumende C.M., Division of Respirology and Critical Illness, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Shatri H., Division of Psychosomatic and Palliative Medicine, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo, Jakarta, Indonesia; Koesnoe S., Division of Allergy and Immunology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Umbarawan Y., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Putranto R., Division of Psychosomatic and Palliative Medicine, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo, Jakarta, Indonesia; Nasution S.A., Division of Cardiology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo, Jakarta, Indonesia	Background: Asthma is a disease characterized by chronic airway inflammation, however one-third of asthmatic cases did not respond adequately. Inhaled magnesium has been proposed as a treatment for unresponsive asthma cases. However, its role remains controversial. This review evaluates the effectiveness and safety of nebulized magnesium compared to standard therapy (Beta Agonist, Anticholinergic, Corticosteroid) in adults with acute asthma attacks. Methods: The protocol has been registered in PROSPERO. A literature search was conducted through PubMed/MEDLINE, Cochrane, ProQuest, and Google Scholar, and using the keywords “inhaled magnesium” and “asthma”. Manual searches were carried out through data portals. Journal articles included are randomized controlled trials. The assessment risk of bias was performed using Version 2 of the Cochrane risk-of-bias tool for randomized trials. Results: There are five articles included in this review. There is no significant difference in readmission rate and oxygen saturation in the magnesium group compared to control (RR 1; 95% CI 0.92 to 1,08; p= 0,96 and MD 1,82; 95% CI-0.89 to 4.53; p= 0.19, respectively). There is a significant reduction of respiratory rate and clinical severity in magnesium (MD-1,72; 95% CI-3,1 to 0.35; p= 0.01, RR 0.29; 95% CI 0.17 to 0.69; p <0.001, respectively). There was a higher risk of side effects in the magnesium group (HR 1.56; 95%CI 1.05 to 2.32; p= 0.03). However, the side effects are relatively mild such as hypotension and nausea. Conclusion: Inhaled magnesium improves the outcome of asthmatic patients, especially in lung function, clinical severity, and respiratory rate. Moreover, inhaled magnesium is safe to be given. © 2024, Indonesian Society of Internal Medicine. All rights reserved.	Adult; Asthma; Inhaled Magnesium	Adult; Anti-Asthmatic Agents; Asthma; Drug Therapy, Combination; Hospitalization; Humans; Magnesium; antiasthmatic agent; magnesium; adult; asthma; combination drug therapy; hospitalization; human; meta analysis			Indonesian Society of Internal Medicine	01259326	38561891	Article	Q3	282	15714	View
322	Simanjuntak R.B.; Lie K.C.; Rumende C.M.; Abdullah M.; Shatri H.; Koesnoe S.; Nainggolan L.; Rizka A.	Simanjuntak, Rohayat B. (58976340400); Lie, Khie Chen (56606750200); Rumende, Cleopas M. (14325966300); Abdullah, Murdani (7103393434); Shatri, Hamzah (28767986500); Koesnoe, Soekamto (26028015000); Nainggolan, Leonard (23498394800); Rizka, Aulia (57203243658)	58976340400; 56606750200; 14325966300; 7103393434; 28767986500; 26028015000; 23498394800; 57203243658	Validation of Drug Resistance in Pneumonia (DRIP) Score as Empirical Antibiotic Failure Predictor in Community-Acquired Pneumonia Patients in Cipto Mangunkusumo Hospital	2024	Acta Medica Indonesiana	56	1	55	62	7	0	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85189801900&partnerID=40&md5=3115607e002981f88647564cad4325e9	Division of Respirology and Critical Care, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Tropical Medicine and Infectious Disease, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Psychosomatic, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Allergy and Clinical Immunology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Geriatrics, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Simanjuntak R.B., Division of Respirology and Critical Care, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Lie K.C., Division of Tropical Medicine and Infectious Disease, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rumende C.M., Division of Respirology and Critical Care, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Abdullah M., Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Shatri H., Division of Psychosomatic, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Koesnoe S., Division of Allergy and Clinical Immunology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Nainggolan L., Division of Tropical Medicine and Infectious Disease, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rizka A., Division of Geriatrics, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Background: The incidence of CAP due to Drug-Resistant Pathogen (DRP) requires broad-spectrum antibiotic therapy, Drugs Resistance in Pneumonia (DRIP) score can predict these cases. The use of the DRIP score can prevent antibiotic failure and long hospitalization, but validation is needed so that the DRIP score can be used according to the local community at Cipto Mangunkusumo National Central Public Hospital. Methods: This research is a retrospective cohort study in CAP patients who were hospitalized during the period January 2019 to June 2020. Data were taken from medical records. Failure of empiric antibiotics occurs when one of these criteria is found: patient mortality, ICU transfer, and escalation of antibiotics as well as length of stay. Results: 480 patients met the criteria. There were 331 patients (69%) with a DRIP score of <4 and 149 patients (31%) with a DRIP score of≥4. A total of 283 patients (59%) of antibiotic failures were detailed in 174 patients with a DRIP score <4 and 109 patients DRIP score ≥4. DRIP calibration using the Hosmer-Lemeshow test obtained p-value= 0.667 (p>0.05). AUC observations on the ROC curve obtained 0.651 (95% CI; 0.601-0.700). Conclusion: The DRIP score has low accuracy performance and calibration value in predicting empirical antibiotic failure and poor discriminatory value. © 2024, Indonesian Society of Internal Medicine. All rights reserved.	antibiotics failure; Community-Acquired Pneumonia; DRIP score; Drug-Resistant Pathogens	Anti-Bacterial Agents; Community-Acquired Infections; Hospitalization; Hospitals; Humans; Pneumonia; Retrospective Studies; antiinfective agent; community acquired infection; hospital; hospitalization; human; pneumonia; retrospective study			Indonesian Society of Internal Medicine	01259326	38561875	Article	Q3	282	15714	View
327	Kurniawan J.; Teressa M.	Kurniawan, Juferdy (57193251655); Teressa, Maria (57957998500)	57193251655; 57957998500	Insulin Use and The Risk of Hepatocellular Carcinoma: Insights and Implications	2024	Acta Medica Indonesiana	56	1	107	113	6	0	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85189783996&partnerID=40&md5=6df21ce97cf287246728806a4f347975	Division of Hepatobiliary, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Kurniawan J., Division of Hepatobiliary, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Teressa M., Division of Hepatobiliary, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia	In recent years, the incidence of diabetes mellitus and hepatocellular carcinoma (HCC) has been increasing worldwide, in the context of an increasing prevalence of non-alcoholic fatty liver disease (NAFLD). In patients with diabetes mellitus, exogenous insulin is commonly prescribed and used in long-term settings. Recent studies suggest that insulin use may elevate the risk of HCC. A substantial body of work seeks to unpack the association between insulin use and the risk of developing HCC, although there may be conflicting evidence. Further validation is necessary to clarify the true relationship between insulin mechanisms and its hepatocarcinogenic effect. Given the burden of diabetic patients developing HCC, diabetologists and hepatologists must collaborate, particularly regarding the prevention and surveillance of HCC in diabetic patients. © 2024, Indonesian Society of Internal Medicine. All rights reserved.	hepatocellular carcinoma; insulin; insulin use; risk	Carcinoma, Hepatocellular; Diabetes Mellitus; Humans; Insulin; Liver Neoplasms; Non-alcoholic Fatty Liver Disease; Risk Factors; insulin; complication; diabetes mellitus; human; liver cell carcinoma; liver tumor; nonalcoholic fatty liver; pathology; risk factor			Indonesian Society of Internal Medicine	01259326	38561879	Review	Q3	282	15714	View
341	Purnamasari D.	Purnamasari, Dyah (36519537700)	36519537700	Challenges in Diagnosis and Treatment of Male Hypogonadism	2024	Acta Medica Indonesiana	56	1	1	2	1	0	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85189835995&partnerID=40&md5=fe2020257287a16b8c1a0a49277f666d	Division of Endocrinology and Metabolisms, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Purnamasari D., Division of Endocrinology and Metabolisms, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Hypogonadism is a condition characterized by diminished or absent production of sex hormones by the testicles in men and the ovaries in women. Hypogonadism is classified into primary and secondary hypogonadism. Each type of hypogonadism can be caused by congenital and acquired factors. There are many factors that contribute to the occurrence of hypogonadism, including genetic and developmental disorders, infection, kidney disease, liver disease, autoimmune disorders, chemotherapy, radiation, surgery, and trauma. This represents the considerable challenge in diagnosing hypogonadism. The goals of treatment include restore sexual functionality and well-being, initiating and sustaining virilization, osteoporosis prevention, normalize growth hormone levels in elderly men if possible, and restoring fertility in instances of hypogonadotropic hypogonadism. The main approach to treating hypogonadism is hormone replacement therapy. Male with prostate cancer, breast cancer, and untreated prolactinoma are contraindicated for hormone replacement therapy. When selecting a type of testosterone therapy for male with hypogonadism, several factors need to be considered, such as the diversity of treatment response and the type of testosterone formulation. The duration of therapy depends on individual response, therapeutic goals, signs and symptoms, and hormonal levels. The response to testosterone therapy is evaluated based on symptoms and signs as well as improvements in hormone profiles in the blood. Endocrine Society Clinical Practice Guideline recommend therapeutic goals based on the alleviation of symptoms and signs, as well as reaching testosterone levels between 400 – 700 ng/dL (one week after administering testosterone enanthate or cypionate) and maintaining baseline hematocrit. Hormone therapy is the primary modality in the management of hypogonadism. The variety of signs and symptoms makes early diagnosis of this condition challenging. Moreover, administering hypogonadism therapy involves numerous considerations influenced by various patient factors and the potential for adverse effects. This poses a challenge for physicians to provide targeted hypogonadism therapy with minimal complications. © 2024, Acta Med Indones. All rights reserved.	dianosis; hormone; hypogonadism; therapy	Aged; Female; Hormone Replacement Therapy; Humans; Hypogonadism; Male; Testis; Testosterone; testosterone; aged; female; hormone substitution; human; hypogonadism; male; testis			Indonesian Society of Internal Medicine	01259326	38561883	Editorial	Q3	282	15714	View
351	Nasution S.A.; Sukrisman L.; Salim S.; Hustrini N.M.; Hidayat R.; Yunihastuti E.; Pitoyo C.W.; Rachman A.; Rahmadini S.; Adgani G.G.; Rahmani N.I.	Nasution, Sally Aman (57189373134); Sukrisman, Lugyanti (8661764000); Salim, Simon (57197712710); Hustrini, Ni Made (57200424892); Hidayat, Rudi (58976441900); Yunihastuti, Evy (57221273925); Pitoyo, Ceva W. (26022606900); Rachman, Andhika (15056701600); Rahmadini, Sayang (58976309800); Adgani, Ginulur Gensyaf (58976570000); Rahmani, Nurul Inayah (58976033600)	57189373134; 8661764000; 57197712710; 57200424892; 58976441900; 57221273925; 26022606900; 15056701600; 58976309800; 58976570000; 58976033600	The Impact on Working Conditions and Income Amongst Internists in Indonesia: Lesson Learned from the COVID-19 Pandemic	2024	Acta Medica Indonesiana	56	1	116	125	9	0	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85189775785&partnerID=40&md5=95898412b8580f1b00a07281475d7beb	Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Indonesian Society of Internal Medicine, (Perhimpunan Dokter Spesialis Penyakit Dalam Indonesia), Jakarta, Indonesia	Nasution S.A., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia, Indonesian Society of Internal Medicine, (Perhimpunan Dokter Spesialis Penyakit Dalam Indonesia), Jakarta, Indonesia; Sukrisman L., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia, Indonesian Society of Internal Medicine, (Perhimpunan Dokter Spesialis Penyakit Dalam Indonesia), Jakarta, Indonesia; Salim S., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia, Indonesian Society of Internal Medicine, (Perhimpunan Dokter Spesialis Penyakit Dalam Indonesia), Jakarta, Indonesia; Hustrini N.M., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia, Indonesian Society of Internal Medicine, (Perhimpunan Dokter Spesialis Penyakit Dalam Indonesia), Jakarta, Indonesia; Hidayat R., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia, Indonesian Society of Internal Medicine, (Perhimpunan Dokter Spesialis Penyakit Dalam Indonesia), Jakarta, Indonesia; Yunihastuti E., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia, Indonesian Society of Internal Medicine, (Perhimpunan Dokter Spesialis Penyakit Dalam Indonesia), Jakarta, Indonesia; Pitoyo C.W., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia, Indonesian Society of Internal Medicine, (Perhimpunan Dokter Spesialis Penyakit Dalam Indonesia), Jakarta, Indonesia; Rachman A., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia, Indonesian Society of Internal Medicine, (Perhimpunan Dokter Spesialis Penyakit Dalam Indonesia), Jakarta, Indonesia; Rahmadini S., Indonesian Society of Internal Medicine, (Perhimpunan Dokter Spesialis Penyakit Dalam Indonesia), Jakarta, Indonesia; Adgani G.G., Indonesian Society of Internal Medicine, (Perhimpunan Dokter Spesialis Penyakit Dalam Indonesia), Jakarta, Indonesia; Rahmani N.I., Indonesian Society of Internal Medicine, (Perhimpunan Dokter Spesialis Penyakit Dalam Indonesia), Jakarta, Indonesia	Internists are at the forefront of providing care for COVID-19 patients. This situation adds more strain on already overburdened internists, particularly in Indonesia, where resources are scarce and unevenly distributed. The pandemic altered working conditions due to restrictions and regulatory changes. Multiple evidence exists for the effect of the COVID-19 pandemic on physicians’ well-being, but less is known about its impact on their work dynamics and livelihoods. This study provides some lessons learned during the COVID-19 pandemic regarding the changes in working conditions and earnings experienced by Indonesian internists. There were 3,115 and 1,772 participants in the first and second survey, respectively. After one year, the proportion of internists handling COVID-19 cases, including critical COVID-19 cases, increased; with fewer internists over 60 years old involved. Working hours, number of patients, and monthly earnings decreased for the majority of internists. The increased workload was experienced by most participants one year of the pandemic, predominantly reported by female internists. The COVID-19 pandemic caused a considerable impact on working conditions and income amongst internists in Indonesia. These findings may provide information to institutions in formulating strategies and tools to improve the working conditions and livelihoods of internists in Indonesia amidst the pandemic and potential public health emergencies in the future. © 2024, Indonesian Society of Internal Medicine. All rights reserved.	COVID-19; internist; LMIC; monthly earnings; working conditions	COVID-19; Female; Humans; Indonesia; Middle Aged; Pandemics; Physicians; Surveys and Questionnaires; coronavirus disease 2019; female; human; Indonesia; middle aged; pandemic; physician; questionnaire	Indonesian Society of Internal Medicine; Perhimpunan Dokter Spesialis Penyakit Dalam Indonesia; PAPDI	This study is supported by the Indonesian Society of Internal Medicine (Perhimpunan Dokter Spesialis Penyakit Dalam Indonesia, PAPDI). FUNDING This research received no specific grant from any funding agency, commercial or not-for-profit sectors.	Indonesian Society of Internal Medicine	01259326	38561884	Article	Q3	282	15714	View
354	Lubis D.A.; Subekti I.; Yunir E.; Irawan C.; Hestiantoro A.; Lestari S.W.; Kekalih A.; Pasaribu M.M.B.; Syafril S.	Lubis, Dian Anindita (57201672736); Subekti, Imam (24336854300); Yunir, Em (36520254800); Irawan, Cosphiadi (28767651600); Hestiantoro, Andon (8743255100); Lestari, Silvia Werdhy (55980501200); Kekalih, Aria (55633562200); Pasaribu, Merci Monica Br (57391787700); Syafril, Santi (57216533797)	57201672736; 24336854300; 36520254800; 28767651600; 8743255100; 55980501200; 55633562200; 57391787700; 57216533797	Proportion of Hypogonadism in Transfusion-Dependent Thalassemia Patients and Its Contributing Factors	2024	Acta Medica Indonesiana	56	1	13	19	6	0	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85189792845&partnerID=40&md5=466f3ec6d7ee230f0c355507e5c00651	Doctoral Program in Medical Sciences, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Division of Endocrinology Metabolic, Department of Internal Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia; Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Hematology and Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Reproductive Immunoendocrinology, Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Medical Biology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Clinical Pathology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Lubis D.A., Doctoral Program in Medical Sciences, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Division of Endocrinology Metabolic, Department of Internal Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia; Subekti I., Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Yunir E., Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Irawan C., Division of Hematology and Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Hestiantoro A., Division of Reproductive Immunoendocrinology, Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Lestari S.W., Department of Medical Biology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Kekalih A., Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Pasaribu M.M.B., Department of Clinical Pathology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Syafril S., Division of Endocrinology Metabolic, Department of Internal Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia	Background: Beta thalassemia is a lifelong disease involving malformed red blood cells (RBC). One of the disease’s complications is hypogonadism, in which adults tend to exhibit regression in sexual characteristics, experience sexual dysfunction, and therefore have a lower quality of life. Around 3-10% of the Indonesian population carries the beta-thalassemia gene. This study aimed to see the proportions of hypogonadism in transfusion-dependent thalassemia patients and its contributing factors. Methods: This is a cross-sectional study involving 60 male patients admitted to three Indonesian general hospitals from July 2022 to July 2023. All patients were diagnosed with beta-thalassemia via chromatography hemoglobin analysis. We performed a single-time physical examination and laboratory examinations to determine FSH, LH, and free testosterone levels. The correlation between Hb and sexual hormone levels was analyzed using Spearman’s rank correlation coefficient. ROC curve analysis was conducted afterward. All statistical analysis was done in SPSS version 29. Results: 31 out of 60 thalassemia patients had hypogonadism. Pre-transfusion Hb count was found to be linearly correlated with FSH (r = 0.388, p = 0.049), LH (r = 0.338, p = 0.008), and free testosterone (r = 0.255, p = 0.049). ROC analysis indicated that pre-transfusion Hb was viable as a predictor for hypogonadism (AUC = 0.655, 65.5% sensitivity, 67.7% specificity). Conclusion: We confirmed the role of pre-transfusion Hb count as a potential predictor for hypogonadism due to the tissue hypoxia mechanism and transfusion-related iron overload in TDT patients. Decreased Hb is linearly correlated with FSH, LH, and testosterone levels. Decreased Hb also downregulates these factors. © 2024, Indonesian Society of Internal Medicine. All rights reserved.	hypogonadism; Pre-transfusion hemoglobin; transfusion-dependent thalassemia	Adult; beta-Thalassemia; Cross-Sectional Studies; Follicle Stimulating Hormone; Humans; Hypogonadism; Male; Quality of Life; Testosterone; Thalassemia; follitropin; testosterone; adult; beta thalassemia; complication; cross-sectional study; human; hypogonadism; male; quality of life; thalassemia			Indonesian Society of Internal Medicine	01259326	38561881	Article	Q3	282	15714	View
370	Rajabto W.; Singh G.; Mulyadi C.K.; Chandika V.; Pyrhadistya M.	Rajabto, Wulyo (36519576100); Singh, Gurmeet (57209127647); Mulyadi, Calvin Kurnia (58976846400); Chandika, Vitya (57742604100); Pyrhadistya, Maria (58976181400)	36519576100; 57209127647; 58976846400; 57742604100; 58976181400	The Association between Anemia and Mortality of Severe Pneumonia COVID-19 Patients in the High Care Unit of a Tertiary Hospital in Jakarta	2024	Acta Medica Indonesiana	56	1	63	68	5	0	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85189818022&partnerID=40&md5=64c651718f65eb4b8f6b15de43c03174	Division of Hematology-Medical Oncology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Respirology and Critical Care, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Departement of Internal Medicine, Fatmawati Hospital, Jakarta, Indonesia; Residency program in Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Rajabto W., Division of Hematology-Medical Oncology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Singh G., Division of Respirology and Critical Care, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Mulyadi C.K., Departement of Internal Medicine, Fatmawati Hospital, Jakarta, Indonesia; Chandika V., Residency program in Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Pyrhadistya M., Division of Hematology-Medical Oncology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Background: Numerous studies explored the association between anemia and mortality in patients with severe pneumonia due to COVID-19. However, the findings were inconsistent. Therefore, this study was conducted to investigate the association between anemia at HCU admission and in-hospital mortality in severe pneumonia COVID-19 patients. Methods: This retrospective cohort study obtained data on 110 COVID-19 patients with severe pneumonia who were admitted to the HCU between January, 1st 2021, and May 31st, 2021. Patients were categorized as anemic and non-anemic based on the World Health Organization (WHO) guidelines. The demographic and clinical characteristics of the subjects were described. The Chi-squared test was carried out followed by a logistic regression test to determine the association of anemia and mortality. Results: Anemia was observed in 31% of 110 patients with severe pneumonia COVID-19. The source population consisted of 60.9% men and 39.1% women with a median age of 58 years. The most prevalent comorbidity was hypertension (38.2%), followed by diabetes mellitus (27.2%), renal diseases (19.1%) and heart diseases (10%). TAnemia on HCU admission was associated with in-hospital mortality in patients with severe pneumonia COVID-19 (RR: 2.794, 95% CI 1.470-5.312). After adjusting comorbidities as confounding factors, anemia was independently associated with mortality (RR: 2.204, 95% CI: 1.124-4.323, P < 0.021). The result also showed anemic patients had longer lengths of stay and higher levels of D-dimer than non-anemic patients. The median duration length of stay among the anemic and non-anemic was 16 (11-22) and 13 (9-17) days, respectively. The median D-dimer among the anemic and non-anemic was 2220 μg/ml and 1010 μg/ml, respectively. Conclusion: There is a significant association between anemia at HCU admission and mortality in patients with severe pneumonia COVID-19 during hospitalization. © 2024, Indonesian Society of Internal Medicine. All rights reserved.	Anemia; Mortality; Retrospective Cohort; Severe Pneumonia COVID-19	Anemia; COVID-19; Female; Hospital Mortality; Humans; Male; Middle Aged; Pneumonia; Retrospective Studies; Risk Factors; Tertiary Care Centers; anemia; complication; coronavirus disease 2019; female; hospital mortality; human; male; middle aged; pneumonia; retrospective study; risk factor; tertiary care center			Indonesian Society of Internal Medicine	01259326	38561876	Article	Q3	282	15714	View

Publikasi Scopus 2024 per tanggal 30 Juni 2024 (499 artikel)