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Sudjono C.; Quinncilla K.H.; Qonita M.; Wijaya N.J.; Kurnain D. |
Sudjono, Clinton (59196697600); Quinncilla, Kiara Hanna (59136515900); Qonita, Ms (59195443000); Wijaya, Nicholas Jason (58483356100); Kurnain, Dave (59196070600) |
59196697600; 59136515900; 59195443000; 58483356100; 59196070600 |
Early Menarche as a Protective Factor Against Cardiovascular Events: A Systematic Review and Meta-analysis |
2024 |
Anatolian journal of cardiology |
28 |
7 |
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329 |
338 |
9 |
0 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85197189251&doi=10.14744%2fAnatolJCardiol.2024.3996&partnerID=40&md5=fcfbfda7ab7b31922e8582c997fc0e7a |
Department of Cardiology, Faculty of Medicine, Tarumanagara University, Jakarta, Indonesia; Sebelas Maret University, Surakarta, Indonesia; Jenderal Soedirman University, Purwokerto, Indonesia; Undergraduate Medical Program, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Sudjono C., Department of Cardiology, Faculty of Medicine, Tarumanagara University, Jakarta, Indonesia; Quinncilla K.H., Sebelas Maret University, Surakarta, Indonesia; Qonita M., Jenderal Soedirman University, Purwokerto, Indonesia; Wijaya N.J., Undergraduate Medical Program, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Kurnain D., Department of Cardiology, Faculty of Medicine, Tarumanagara University, Jakarta, Indonesia |
BACKGROUND: Women are often neglected in cardiovascular health prevention. Age at menarche (AAM) has been linked to cardiovascular (CVD) disease in women and is potentially identified as one of the significant CVD risk factor. However, there is still limited comprehensive evidence addressing this issue. This systematic review and meta-analysis aimed to investigate how early menarche affects the outcome of all-cause mortality, CVD mortality, total cardiovascular disease event, stroke (ischemic, hemorrhagic, and total stroke), and coronary heart disease (CHD). METHOD: The Cochrane Library, MEDLINE, Embase, ScienceDirect, and Google Scholar databases were searched from March 2013 to March 2023 for cohorts investigating the effect of early onset of menarche on CVD events with a minimum follow-up period of 5 years. Studies that observed specific population and/or included women with a history of CVD at baseline were excluded. The Newcastle-Ottawa scale was used for risk of bias assessment for each cohort included. The data were presented as dichotomous measure using risk ratios. I2 statistics were utilized to evaluate the heterogeneity of presented data. RESULTS: Thirteen cohorts included 18 626 799 female patients with ages ranging from 43 to 62.6 years. These reported 6 estimates each for CHD (5 483 298 patients) and all-cause mortality (1 595 878 patients), 5 estimates each for total stroke (2 941 321 patients) and CVD mortality (1 706 742 patients), 4 estimates each for total CVD events (3 988 311 patients) and ischemic stroke (2 434 580 patients), and 1 estimate for hemorrhagic stroke (66 104 patients). Our study found that events of CHD were significantly lower in early menarche (RR 0.57; 95% CI 0.41-0.78; P <.00001), as well as total stroke (RR 0.51; 95% CI 0.35-0.73; P =.0003), CVD mortality (RR 0.47; 95% CI 0.22-0.98; P =.04), total CVD events (RR 0.44; 95% CI 0.25-0.76; P =.003), ischemic stroke (RR 0.31; 95% CI 0.15-0.61; P <.0008), and hemorrhagic stroke (RR 0.12; 95% CI 0.07-0.20; P <.00001); and insignificantly higher in all-cause mortality (RR 0.90, 95% CI 0.76-1.06, P =.20). CONCLUSION: In our study, cardiovascular events are lower in women with early menarche; hence, the later age of menarche is a potential risk factor to be considered when assessing CVD risk in a patient. However, our sample characteristics were heterogenous, and we did not consider other female hormonal factors that might potentially contribute to the CVD outcomes observed; thus, further studies are needed to clarify. |
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Age Factors; Cardiovascular Diseases; Female; Humans; Menarche; Middle Aged; Protective Factors; Risk Factors; age; cardiovascular disease; female; human; menarche; meta analysis; middle aged; mortality; prevention and control; protection; risk factor |
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21492271 |
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38940409 |
Article |
Q3 |
290 |
15434 |
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19 |
Siregar G.O.; Harianja M.; Adella J.; Krismawati H.; Sundari E.S.; Ataupah M.R.; Laiskodat R.D.; Bøgh C.; Soebono H.; Grijsen M.L. |
Siregar, Gladys O. (58876649500); Harianja, Maria (58876435800); Adella, Jacklyn (58994793100); Krismawati, Hana (56572770100); Sundari, Evivana S. (58876435900); Ataupah, Messe R. (58993911900); Laiskodat, Ruth D. (58994354700); Bøgh, Claus (6602120205); Soebono, Hardyanto (6508242918); Grijsen, Marlous L. (25225113700) |
58876649500; 58876435800; 58994793100; 56572770100; 58876435900; 58993911900; 58994354700; 6602120205; 6508242918; 25225113700 |
Leprosy identified in Sumba Island, eastern Indonesia: elimination targets under threat |
2024 |
The Lancet Regional Health - Southeast Asia |
26 |
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100409 |
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0 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85190856063&doi=10.1016%2fj.lansea.2024.100409&partnerID=40&md5=4f24b635df4260f90f0d5f674d9efa33 |
Sumba Foundation, Sumba, Indonesia; Center of Health System and Strategy, Ministry of Health, Jakarta, Indonesia; Department of Dermatology and Venereology, Siloam Hospital, Kupang, Indonesia; Province Health Office, East Nusa Tenggara, Kupang, Indonesia; Department of Dermatology and Venereology, Gadjah Mada University, Yogyakarta, Indonesia; Oxford University Clinical Research Unit Indonesia, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, United Kingdom |
Siregar G.O., Sumba Foundation, Sumba, Indonesia; Harianja M., Sumba Foundation, Sumba, Indonesia; Adella J., Sumba Foundation, Sumba, Indonesia; Krismawati H., Center of Health System and Strategy, Ministry of Health, Jakarta, Indonesia; Sundari E.S., Department of Dermatology and Venereology, Siloam Hospital, Kupang, Indonesia; Ataupah M.R., Province Health Office, East Nusa Tenggara, Kupang, Indonesia; Laiskodat R.D., Province Health Office, East Nusa Tenggara, Kupang, Indonesia; Bøgh C., Sumba Foundation, Sumba, Indonesia; Soebono H., Department of Dermatology and Venereology, Gadjah Mada University, Yogyakarta, Indonesia; Grijsen M.L., Oxford University Clinical Research Unit Indonesia, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, United Kingdom |
[No abstract available] |
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awareness; disease burden; disease transmission; health care personnel; human; leprosy; multibacillary leprosy; nerve injury; Note; paucibacillary leprosy; polypharmacy; primary health care; skin care; teledermatology; telemedicine |
Wellcome Trust, WT; Sumba Foundation |
Funding text 1: The project was financially supported by the Wellcome Trust Africa Asia Programme Vietnam. The authors declare that they have no conflicts of interest. ; Funding text 2: We extend our sincere gratitude to all Sumba Foundation healthcare workers. We wish to acknowledge Ben Naafs for sharing his expertise on leprosy with the clinical team. |
Elsevier Ltd |
27723682 |
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Note |
#N/A |
#N/A |
#N/A |
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25 |
Manurung M.D.; Sonnet F.; Hoogerwerf M.-A.; Janse J.J.; Kruize Y.; Bes-Roeleveld L.D.; König M.; Loukas A.; Dewals B.G.; Supali T.; Jochems S.P.; Roestenberg M.; Coppola M.; Yazdanbakhsh M. |
Manurung, Mikhael D. (57210737315); Sonnet, Friederike (57212529488); Hoogerwerf, Marie-Astrid (55210214000); Janse, Jacqueline J. (55959038600); Kruize, Yvonne (6602745057); Bes-Roeleveld, Laura de (59220077400); König, Marion (57183759300); Loukas, Alex (7006573927); Dewals, Benjamin G. (8883647300); Supali, Taniawati (6602742029); Jochems, Simon P. (57209686200); Roestenberg, Meta (16305767300); Coppola, Mariateresa (55586642100); Yazdanbakhsh, Maria (7006269286) |
57210737315; 57212529488; 55210214000; 55959038600; 6602745057; 59220077400; 57183759300; 7006573927; 8883647300; 6602742029; 57209686200; 16305767300; 55586642100; 7006269286 |
Controlled human hookworm infection remodels plasmacytoid dendritic cells and regulatory T cells towards profiles seen in natural infections in endemic areas |
2024 |
Nature Communications |
15 |
1 |
5960 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85198640521&doi=10.1038%2fs41467-024-50313-0&partnerID=40&md5=08405f618c28132db8822f4b19fbfda8 |
Leiden University Center for Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands; Centre for Molecular Therapeutics, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns, Australia; Laboratory of Immunology-Vaccinology, FARAH, University of Liège, Liège, Belgium; Department of Parasitology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia |
Manurung M.D., Leiden University Center for Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands; Sonnet F., Leiden University Center for Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands; Hoogerwerf M.-A., Leiden University Center for Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands; Janse J.J., Leiden University Center for Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands; Kruize Y., Leiden University Center for Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands; Bes-Roeleveld L.D., Leiden University Center for Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands; König M., Leiden University Center for Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands; Loukas A., Centre for Molecular Therapeutics, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns, Australia; Dewals B.G., Laboratory of Immunology-Vaccinology, FARAH, University of Liège, Liège, Belgium; Supali T., Department of Parasitology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Jochems S.P., Leiden University Center for Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands; Roestenberg M., Leiden University Center for Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands; Coppola M., Leiden University Center for Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands; Yazdanbakhsh M., Leiden University Center for Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands |
Hookworm infection remains a significant public health concern, particularly in low- and middle-income countries, where mass drug administration has not stopped reinfection. Developing a vaccine is crucial to complement current control measures, which necessitates a thorough understanding of host immune responses. By leveraging controlled human infection models and high-dimensional immunophenotyping, here we investigated the immune remodeling following infection with 50 Necator americanus L3 hookworm larvae in four naïve volunteers over two years of follow-up and compared the profiles with naturally infected populations in endemic areas. Increased plasmacytoid dendritic cell frequency and diminished responsiveness to Toll-like receptor 7/8 ligand were observed in both controlled and natural infection settings. Despite the increased CD45RA+ regulatory T cell (Tregs) frequencies in both settings, markers of Tregs function, including inducible T-cell costimulatory (ICOS), tumor necrosis factor receptor 2 (TNFR2), and latency-associated peptide (LAP), as well as in vitro Tregs suppressive capacity were higher in natural infections. Taken together, this study provides unique insights into the immunological trajectories following a first-in-life hookworm infection compared to natural infections. © The Author(s) 2024. |
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Adult; Animals; Dendritic Cells; Endemic Diseases; Female; Hookworm Infections; Humans; Immunophenotyping; Male; Necator americanus; Necatoriasis; T-Lymphocytes, Regulatory; Young Adult; CD45RA antigen; inducible T cell costimulator ligand; latency associated peptide; toll like receptor 7; toll like receptor 8; tumor necrosis factor receptor 2; biostimulation; cell component; infectious disease; public health; adult; Article; CD4+ T lymphocyte; cell compartmentalization; cell count; cell expansion; clinical article; controlled study; endemic disease; follow up; hookworm infection; human; human cell; immunoregulation; larva; lymphocyte count; lymphocyte function; Necator americanus; plasmacytoid dendritic cell; regulatory T lymphocyte; animal; dendritic cell; endemic disease; female; hookwo |
Indonesian Endowment Fund for Education; Dioraphte Foundation; European Commission, EC; Fonds De La Recherche Scientifique - FNRS, FNRS; NWO; LPDP, (S-1598/LPDP.3/2016) |
We would like to thank the Flow Cytometry Core Facility at Leiden University Medical Center for assistance with our flow and mass cytometry experiments. This study is part of the EDCTP2 programme supported by the European Union. The Controlled Human Hookworm Infection in Leiden (CHHIL) trial was funded by the Dioraphte Foundation and by NWO Spinoza prize of M.Y. M.D.M. is funded by the Indonesian |
Nature Research |
20411723 |
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39013877 |
Article |
Q1 |
5116 |
258 |
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27 |
Atmodiwirjo P.; Ramadan M.R.; Sapphira E.; Djohan M.; Ralena N.A.; Amanda N.F. |
Atmodiwirjo, Parintosa (57203016968); Ramadan, Mohamad R. (57222667572); Sapphira, Elrica (59213850300); Djohan, Michael (59205590300); Ralena, Nadhira A. (57214093149); Amanda, Nadira F. (59205390500) |
57203016968; 57222667572; 59213850300; 59205590300; 57214093149; 59205390500 |
Fluorescence Intensity between Standard versus Diluted Indocyanine Green to Evaluate Flap Perfusion in Rats |
2024 |
Plastic and Reconstructive Surgery - Global Open |
12 |
7 |
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e5948 |
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0 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85198189408&doi=10.1097%2fGOX.0000000000005948&partnerID=40&md5=e878745493a992780d45de0fbaa4be30 |
Division of Plastic Reconstructive and Aesthetic Surgery, Department of Surgery, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Atmodiwirjo P., Division of Plastic Reconstructive and Aesthetic Surgery, Department of Surgery, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Ramadan M.R., Division of Plastic Reconstructive and Aesthetic Surgery, Department of Surgery, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Sapphira E., Division of Plastic Reconstructive and Aesthetic Surgery, Department of Surgery, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Djohan M., Division of Plastic Reconstructive and Aesthetic Surgery, Department of Surgery, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Ralena N.A., Division of Plastic Reconstructive and Aesthetic Surgery, Department of Surgery, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Amanda N.F., Division of Plastic Reconstructive and Aesthetic Surgery, Department of Surgery, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Summary: The ideal dose for indocyanine green (ICG) has not been established yet, although 5 mg per mL is widely accepted for free flap evaluation. Due to its high price and rarity in developing countries, this preliminary study aimed to find the lowest concentration of ICG without reducing the fluorescence quality read by near-infrared camera in animal models. An experimental study was conducted on 25 Wistar rats divided into five groups based on the injected ICG, which was in 5 mg per mL, 3.75 mg per mL, 2.5 mg per mL, 1.25 mg per mL, and 0.5 mg per mL concentrations. The epigastric flap was elevated and confirmed to be vital on the fifth day. Upon confirmation, bolus IV injection of ICG was given via the tail, and the flap was read using near-infrared camera. The 25 different videos are randomized and rated individually in a blind manner by five microsurgeons, chosen beforehand. The videos are evaluated with a scoring system ranging from 0 to 4, assessing fluorescence visibility and flap vasculature. Nonetheless, the intraclass correlation coefficient is 0.779. There was no difference between standard and diluted ICG concentrations to evaluate flap perfusion. The 2.5 mg per mL concentration of ICG was the most favorable. This finding is not clinically relevant for application in human subjects yet. However, this study shows promising results for further usage of ICG in daily practice at a lower cost. © 2024 Lippincott Williams and Wilkins. All rights reserved. |
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Lippincott Williams and Wilkins |
21697574 |
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Article |
Q2 |
671 |
7496 |
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28 |
Mesinovic M.; Wong X.C.; Rajahram G.S.; Citarella B.W.; Peariasamy K.M.; van Someren Greve F.; Olliaro P.; Merson L.; Clifton L.; Kartsonaki C.; Abdukahil S.A.; Abdulkadir N.N.; Abe R.; Abel L.; Abrous A.; Absil L.; Acker A.; Adachi S.; Adam E.; Adriano E.; Adrião D.; Ageel S.A.; Ahmed S.; Aiello M.; Ainscough K.; Airlangga E.; Aisa T.; Hssain A.A.; Tamlihat Y.A.; Akimoto T.; Akmal E.; Qasim E.A.; Alalqam R.; Alberti A.; Al-dabbous T.; Alegesan S.; Alegre C.; Alessi M.; Alex B.; Alexandre K.; Al-Fares A.; Alfoudri H.; Ali A.; Ali I.; Alidjnou K.E.; Aliudin J.; Alkhafajee Q.; Allavena C.; Allou N.; Alves J.; Alves J.M.; Alves R.; Cabrita J.A.; Amaral M.; Amira N.; Ammerlaan H.; Ampaw P.; Andini R.; Andréjak C.; Angheben A.; Angoulvant F.; Ansart S.; Anthonidass S.; Antonelli M.; de Brito C.A.A.; Anwar K.R.; Apriyana A.; Arabi Y.; Aragao I.; Arancibia F.; Araujo C.; Arcadipane A.; Archambault P.; Arenz L.; Arlet J.-B.; Arnold-Day C.; Arora L.; Arora R.; Artaud-Macari E.; Aryal D.; Asaki M.; Asensio A.; Ashley E.A.; Ashraf M.; Assie J.B.; Asyraf A.; Atique A.; Attanyake A.M.U.L.; Auchabie J.; Aumaitre H.; Auvet A.; Azemar L.; Azoulay C.; Bach B.; Bachelet D.; Badr C.; Baig N.; Baillie J.K.; Baird J.K.; Bak E.; Bakakos A.; Bakar N.A.; Bal A.; Balakrishnan M.; Balan V.; Bani-Sadr F.; Barbalho R.; Barbosa N.Y.; Barclay W.S.; Barnett S.U.; Barnikel M.; Barrasa H.; Barrelet A.; Barrigoto C.; Bartoli M.; Baruch J.; Basmaci R.; Basri M.F.H.; Battaglini D.; Bauer J.; Rincon D.F.B.; Dow D.B.; Beane A.; Bedossa A.; Bee K.H.; Begum H.; Behilill S.; Beishuizen A.; Beljantsev A.; Bellemare D.; Beltrame A.; Beltrão B.A.; Beluze M.; Benech N.; Benjiman L.E.; Benkerrou D.; Bennett S.; Bento L.; Berdal J.-E.; Bergeaud D.; Bergin H.; Bertoli G.; Bertolino L.; Bessis S.; Betz A.; Bevilcaqua S.; Bezulier K.; Bhatt A.; Bhavsar K.; Bianco C.; Bidin F.N.; Singh M.B.; Humaid F.B.; Kamarudin M.N.B.; Bisoffi Z.; Bissuel F.; Biston P.; Bitker L.; Bitton J.; Blanco-Schweizer P.; Blier C.; Bloos F.; Blot M.; Blumberg L.; Boccia F.; Bodenes L.; Bogaert D.; Boivin A.-H.; Bolaños I.; Bolze P.-A.; Bompart F.; Bonelli P.; Bonfasius A.; Borges D.; Borie R.; Bosse H.M.; Botelho-Nevers E.; Bouadma L.; Bouchaud O.; Bouchez S.; Bouhmani D.; Bouhour D.; Bouiller K.; Bouillet L.; Bouisse C.; Bounphiengsy T.; Bountthasavong L.; Boureau A.-S.; Bourke J.; Bouscambert M.; Bousquet A.; Bouziotis J.; Boxma B.; Boyer-Besseyre M.; Boylan M.; Bozza F.A.; Braconnier A.; Braga C.; Brandenburger T.; Monteiro F.B.; Brazzi L.; Breen D.; Breen P.; Brewster D.; Brickell K.; Browne A.; Browne S.; Brozzi N.; Brusse-Keizer M.; Buchtele N.; Bugaeva P.; Buisson M.; Buonsenso D.; Burhan E.; Burrell A.; Bustos I.G.; Butnaru D.; Cabie A.; Cabral S.; Caceres E.; Cadoz C.; Garcês R.C.; Callahan M.; Calligy K.; Calvache J.A.; Caminiti C.; Camões J.; Campana V.; Campbell P.; Campisi J.; Canepa C.; Cantero M.; Caraux-Paz P.; Cárcel S.; Cardellino C.S.; Cardoso F.; Cardoso F.; Cardoso N.; Cardoso S.; Carelli S.; Carlacci F.; Carlier N.; Carmoi T.; Carney G.; Carqueja I.; Carret M.-C.; Carrier F.M.; Carroll I.; Carson G.; Carvalho L.; Casanova M.-L.; Cascão M.; Casey S.; Casimiro J.; Cassandra B.; Castañeda S.; Castanheira N.; Castor-Alexandre G.; Castro I.; Catarino A.; Catherine F.-X.; Cattaneo P.; Cavalin R.; Cavalli G.G.; Cavayas A.; Ceccato A.; Cerkovnik S.; Cervantes-Gonzalez M.; Chair A.; Chakveatze C.; Chaleunphon B.; Chan A.; Chand M.; Auger C.C.; Chapplain J.-M.; Charpentier C.; Chas J.; Chatterjee A.; Iñiguez J.S.C.; Chen A.; Chenard L.; Cheng M.P.; Cheret A.; Chetta A.A.; Chiarabini T.; Chica J.; Chidambaram S.K.; Tho L.C.; Chirouze C.; Chiumello D.; Cho H.J.; Cho S.-M.; Cholley B.; Chommanam D.; Chopin M.-C.; Chow T.S.; Chow Y.P.; Christy N.; Chua H.J.; Chua J.; Cidade J.P.; Herreros J.M.C.; Ciullo A.; Clarke E.; Clarke J.; Granado R.C.-D.; Clohisey S.; Codan C.; Cody C.; Coelho A.; Coles J.; Coles M.; Colin G.; Collins M.; Colombo S.M.; Combs P.; Connor M.; Conrad A.; Contreras S.; Conway E.; Cooke G.S.; Copland M.; Cordel H.; Corley A.; Cornelis S.; Cornet A.D.; Corpuz A.J.; Cortegiani A.; Corvaisier G.; Costigan E.; Couffignal C.; Couffin-Cadiergues S.; Courtois R.; Cousse S.; Cregan R.; D’Orleans C.C.; Cristella C.; Croonen S.; Crowl G.; Crump J.; Cruz C.; Csete M.; Cullen A.; Cummings M.; Curley G.; Curlier E.; Curran C.; Custodio P.; da Silva Filipe A.; Da Silveira C.; Dabaliz A.-A.; Dagens A.; Dahly D.; Dalton H.; Dalton J.; Daly S.; Damas J.; Daneman N.; Daniel C.; Dankwa E.A.; Dantas J.; D’Aragon F.; de Jong M.; de Loughry G.; de Mendoza D.; De Montmollin E.; de Oliveira França R.F.; de Pinho Oliveira A.I.; De Rosa R.; De Rose C.; de Silva T.; de Vries P.; Deacon J.; Dean D.; Debard A.; Debray M.-P.; DeCastro N.; Dechert W.; Deconninck L.; Decours R.; Defous E.; Delacroix I.; Delaveuve E.; Delavigne K.; Delfos N.M.; Deligiannis I.; Dell’Amore A.; Delmas C.; Delobel P.; Delsing C.; Demonchy E.; Denis E.; Deplanque D.; Depuydt P.; Desai M.; Descamps D.; Desvallées M.; Dewayanti S.; Dhanger P.; Diallo A.; Diamantis S.; Dias A.; Dias A.; Da Silva F.D.; Diaz J.J.; Diaz P.; Diaz R.; Didier K.; Diehl J.-L.; Dieperink W.; Dimet J.; Dinot V.; Diop F.; Diouf A.; Dishon Y.; Djossou F.; Docherty A.B.; Doherty H.; Dondorp A.M.; Dong A.; Donnelly C.A.; Donnelly M.; Donohue C.; Donohue S.; Donohue Y.; Doran P.; Dorival C.; D’Ortenzio E.; Douangdala P.; Douglas J.J.; Douma R.; Dournon N.; Downer T.; Downey J.; Downing M.; Drake T.; Driscoll A.; Dryden M.; Fonseca C.D.; Dubee V.; Dubos F.; Dubot-Pérès A.; Ducancelle A.; Duculan T.; Dudman S.; Duggal A.; Dunand P.; Dunning J.; Duplaix M.; Durante-Mangoni E.; Durham L., III; Dussol B.; Duthoit J.; Duval X.; Dyrhol-Riise A.M.; Ean S.C.; Echeverria-Villalobos M.; Economopoulos G.; Egan S.; Eira C.; Sanharawi M.E.; Elapavaluru S.; Elharrar B.; Ellerbroek J.; Eloy P.; Elshazly T.; Elyazar I.; Enderle I.; Endo T.; Eng C.C.; Engelmann I.; Enouf V.; Epaulard O.; Escher M.; Esperatti M.; Esperou H.; Santo C.E.; Esposito-Farese M.; Estevão J.; Etienne M.; Ettalhaoui N.; Everding A.G.; Evers M.; Fabre I.; Fabre M.; Faheem A.; Fahy A.; Fairfield C.J.; Fakar Z.; Faria P.; Fateena H.; Fatoni A.Z.; Faure K.; Favory R.; Fayed M.; Feely N.; Feeney L.; Fernandes J.; Fernandes M.A.; Fernandes S.; Ferrand F.-X.; Devouge E.F.; Ferrão J.; Ferrari C.; Ferraz M.; Ferreira B.; Ferreira B.; Ferreira I.; Ferreira S.; Ferrer-Roca R.; Ferriere N.; Ficko C.; Figueiredo-Mello C.; Finlayson W.; Fiorda J.; Flament T.; Flateau C.; Fletcher T.; Florence A.-M.; Florio L.L.; Flynn B.; Flynn D.; Fogliazza F.; Foley C.; Foley J.; Fomin V.; Fonseca T.; Fontela P.; Forsyth S.; Foster D.; Foti G.; Fourn E.; Fowler R.A.; Fraher M.; Franch-Llasat D.; Fraser C.; Fraser J.F.; Freire M.V.; Ribeiro A.F.; Friedrich C.; Fritz R.; Fry S.; Fuentes N.; Fukuda M.; G A.; Gaborieau V.; Gaci R.; Gagliardi M.; Gagnard J.-C.; Gagneux-Brunon A.; Gaião S.; Skeie L.G.; Gallagher P.; Curto E.G.; Gamble C.; Gani Y.; Garan A.; Garcia R.; Garcia-Diaz J.; Garcia-Gallo E.; Garimella N.; 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Lim W.S.; Lima C.; Lina B.; Lina L.; Lind A.; Lingad M.K.; Lingas G.; Lion-Daolio S.; Lissauer S.; Liu K.; Livrozet M.; Lizotte P.; Loforte A.; Lolong N.; Loon L.C.; Lopes D.; Lopez-Colon D.; Lopez-Revilla J.W.; Loschner A.L.; Loubet P.; Loufti B.; Louis G.; Lourenco S.; Lovelace-Macon L.; Low L.L.; Lowik M.; Loy J.S.; Lucet J.C.; Luna C.M.; Lungu O.; Luong L.; Luque N.; Luton D.; Lwin N.; Lyons R.; Maasikas O.; Mabiala O.; Machado M.; Machado S.; Macheda G.; Madiha H.; Maglietta G.; Mahieu R.; Mahy S.; Maia A.R.; Maier L.S.; Maillet M.; Maitre T.; Majori M.; Malfertheiner M.; Malik N.; Mallon P.; Maltez F.; Malvy D.; Mammi P.; Manda V.; Mandei J.M.; Mandelbrot L.; Manetta F.; Mankikian J.; Manning E.; Manuel A.; Malaque C.M.S.; Marino D.; Marino F.; Markowicz S.; Marques A.; Marquis C.; Marsh B.; Marshal M.; Marshall J.; Martelli C.T.; Martin D.-A.; Martin E.; Martin-Blondel G.; Martin-Loeches I.; Martinot M.; Martín-Quiros A.; Martinez F.E.; Martins A.; Martins J.; Martins N.; Rego C.M.; Martucci G.; Martynenko O.; Marwali E.M.; Marzukie M.; Jimenez J.F.M.; Maslove D.; Mason S.; Nor B.M.; Matan M.; Mathieu D.; Mattei M.; Matulevics R.; Maulin L.; Maxwell M.; Maynar J.; Mayxay M.; Mazzoni T.; Sweeney L.M.; McCanny P.; McArthur C.; McCarthy A.; McCarthy A.; McCloskey C.; McConnochie R.; McDermott S.; McDonald S.E.; McElroy A.; McElwee S.; McEneany V.; McEvoy N.; McGeer A.; McKay C.; McKeown J.; McLean K.A.; McNally P.; McNicholas B.; McPartlan E.; Meaney E.; Mear-Passard C.; Mechlin M.; Mehkri O.; Mele F.; Melo L.; Mendes J.J.; Menkiti O.; Menon K.; Mentré F.; Mentzer A.J.; Mercier E. |
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At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods |
2024 |
Scientific Reports |
14 |
1 |
16387 |
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0 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85199015852&doi=10.1038%2fs41598-024-63212-7&partnerID=40&md5=4d554452fe539661a722382eae0ac9e8 |
Department of Engineering Science, University of Oxford, Oxford, United Kingdom; Digital Health Research and Innovation Unit, Institute for Clinical Research, National Institutes of Health (NIH), Shah Alam, Malaysia; Queen Elizabeth II Hospital, Ministry of Health, Kota Kinabalu, Malaysia; Pandemic Sciences Institute, ISARIC, University of Oxford, Oxford, United Kingdom; Department of Medical Microbiology, Amsterdam University Medical Center, Amsterdam, Netherlands; Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom; King Abdulaziz Medical City, Riyadh, Saudi Arabia; Tuanku Fauziah Hospital, Perlis, Malaysia; Chiba University Hospital, Chiba, Japan; INSERM, Paris, France; CUB-Hopital Erasme, Anderlecht, Belgium; Perelman School of Medicine, University of Pennsylvania, Philadelphia, United States; Rinku General Medical Center, Osaka, Japan; Uniklinik University Hospital, Frankfurt, Germany; University Hospital of Parma, Parma, Italy; Centro Hospitalar Vila Nova de Gaia/Espinho, Espinho, Portugal; King Faisal Hospital Research Center, Riyadh, Saudi Arabia; University Hospital, Kerry, Ireland; St Vincents University Hospital, Dublin, Ireland; Murni Teguh Memorial Hospital, Bunda Thamrin Hospital, North Sumatera, Indonesia; Our lady of Lourdes Drogheda, Drogheda, Ireland; Hamad General Hospital, Doha, Qatar; Centre Hospitalier de Saintonge, Saintes, France; Teine Keijinkai Hospital, Sapporo, Japan; Persahabatan Hospital, Jakarta, Indonesia; Beaumont Hospital, Dublin, Ireland; Northwell Health, NY, United States; Al-Adan Hospital, Hadiya, Kuwait; Galway University Hospital, Galway, Ireland; Hospital Vall d’Hebron, Barcelona, Spain; University Hospital Policlinico Paolo Giaccone, Palermo, Italy; School of Informatics, University of Edinburgh, Edinburgh, United Kingdom; Centre Hospitalier Universitaire Rouen (Center Hospitalier Universitaire de Rouen), Rouen, France; Al-Amiri & amp; Jaber Al-Ahmed Hospitals, Kuwait City, Kuwait; St Bernard’s Hospital, Gibraltar, Gibraltar; Sligo University Hospital (Saolta), Sligo, Ireland; Centre Hospitalier Universitaire de Lille, Lille, France; Centre Hospitalier Universitaire de Nantes (Hôpital femme-enfant-adolescent), Nantes, France; Centre Hospitalier Félix-Guyon, Saint-Denis, Reunion; Centro Hospital e Universitário de Coimbra, Coimbra, Portugal; Hospital de São José -U.U.M, Lisbon, Portugal; Hospital Curry Cabral - Intensive Care Unit - UCIP7, Lisbon, Portugal; Sungai Buloh Hospital, Selangor, Malaysia; Catharina Ziekenhuis, Eindhoven, Netherlands; The Ottawa Hospital, Ottawa, Canada; University of Campania, Carseta, Italy; Centre Hospitalier Universitaire Amiens-Picardie, Amiens, France; Department of Infectious - Tropical Diseases and Microbiology, IRCCS Sacro Cuore Hospital - Negrar, Negrar di Valpolicella, Italy; Centre Hospitalier Universitaire de Brest, Brest, France; Kuala Lumpur Hospital, WPKL, Kuala Lumpur, Malaysia; Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; Centro de Pesquisa Aggeu Magalhães, Recife, Fiocruz, Brazil; NICVD Dhaka, Dhaka, Bangladesh; National Cardiovascular Center Harapan Kita Jakarta Indonesia, Jakarta, Indonesia; Intensive Care Department, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia; Centro Hospitalar Universitário do Porto (CHUP), Porto, Portugal; Instituto Nacional Del Tórax, Santiago, Chile; Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione, Palermo, Italy; CISSS Chaudière-Appalaches, Quèbec, Canada; Medical Department II, LMU Hospital Munich, Campus Großhadern, Munich, Germany; Hôpital Européen Georges-Pompidou AP-HP, Paris, France; Groote Schuur Hospital, Cape Town, South Africa; University of Iowa, Iowa City, United States; St. Boniface Hospital, Winnipeg, MB, Canada; CCA Network, Asia, Chiang Mai, Thailand; Fujieda Municipal General Hospital, Fujieda, Japan; Hospital Puerta de Hierro Majadahonda, Madrid, Spain; Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Laos, Vientiane, Thailand; Centre Hospitalier intercommunal de Créteil, Créteil, France; McGill University Health Centre, Montreal, Canada; Centre Hospitalier de Cholet, Cholet, France; Centre Hospitalier de Perpignan, Perpignan, France; Hôpital Lariboisière AP-HP, Paris, France; Hôpital Cochin AP-HP, Paris, France; Centre Hospitalier Intercommunal Villeneuve-Saint-Georges, Villeneuve-Saint-Georges, France; Grande Prairie Queen Elizabeth II, Grande Prairie, Canada; Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom; Rush University Medical Center, Chicago, United States; Sotiria General Hospital, Athens, Greece; Unidade Local de Saúde de Alto Minho, Viana Do Castelo, Portugal; Centre Hospitalier Universitaire de Reims, Reims, France; Instituto de Infectologia Emílio Ribas, Sao Paulo, Brazil; Caja Nacional De Salud, Trinidad, Bolivia; Section of Molecular Virology, Imperial College London, London, United Kingdom; Hospital Universitario de Alava, Araba, Spain; Grand Hôpital de l’Est Francilien (Site de Marne-la-Vallée), Jossigny, France; San Martino Hospital, Genoa, Italy; Clinica Valle de Lilli, Valle del Cauca, Colombia; University of Washington Medical Center - Northwest, Seattle, United States; Critical Care Asia, Bangkok, Thailand; Raja Permaisuri Bainun Hospital, Perak, Malaysia; WHO-ISARIC Clinical Characterisation Protocol & amp; SPRINT-SARI, London, United Kingdom; Medisch Spectrum Twente, Zutphen, Netherlands; Tartu University Hospital, Tartu, Estonia; Hôpital de l’Enfant-Jésus, Quebec, QC, Canada; Follow Up Study Working Group, London, United Kingdom; Sao Camilo Cura D’ars, Fortaleza, Brazil; Centre Hospitalier Universitaire de Lyon - HCL, Lyon, France; Sarawak General Hospital, Sarawak, Malaysia; University of Cincinnati, Cincinnati, United States; Akershus University Hospital, Nordbyhagen, Norway; Ospedale Sacro Cuore Don Calabria, Negrar Di Valpolicella, Italy; Hôpital Raymond-Poincaré, Garches, France; Oklahoma Heart Institute, Oklahoma, United States; Centre Hospitalier Régional et Universitaire de Nancy - Hôpitaux de Brabois, Nancy, France; Hôpital de la Timone, Marseille, France; Ohio State University, Columbus, United States; All India Institute of Medical Sciences, Rishikesh, India; Department of Infectious, Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar, Italy; Thonon-les-Bains, Thonon-les-Bains, France; Civil Hospital Marie Curie, Charleroi, Belgium; Hôpital Lyon Sud - HCL, Lyon, France; The Centre hospitalier universitaire Sainte-Justine, Montreal, Canada; Rio Hortega University Hospital, Valladolid, Spain; Jena University Hospital, Jena, Germany; Centre Hospitalier Universitaire Mitterrand Dijon-Bourgogne, Dijon, France; National Institute for Communicable Diseases, Johannesburg, South Africa; Centre for Inflammation Research, The Queen’s Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh, United Kingdom; Centre Hospitalier de Dax - Côte d’Argent, Dax, France; Universidad del Cauca, Cauca, Colombia; Pratama Rada Bolo Hospital, Karitas Hospital and Waikabubak Hospital, Sumba, Indonesia; Hôpital Bichat Claude-Bernard AP-HP, Paris, France; University Hospital Dusseldorf, Dusseldorf, Germany; Centre Hospitalier Universitaire de Saint-Étienne, Saint-Étienne, France; Hôpital Avicenne, Bobigny, France; Centre hospitalier de l’université de Montréal, Montreal, Canada; Centre Hospitalier de Bourg-en-Bresse, Bourg-en-Bresse, France; Centre Hospitalier Universitaire de Besançon, Besançon, France; Centre Hospitalier Universitaire Grenoble-Alpes, Grenoble, France; Luang Namtha Provincial Hospital, Luang Namtha, Laos; Xieng Khouang Provincial Hospital, Phonsavan, Laos; Centre Hospitalier Universitaire de Nantes (Hôtel-Dieu), Nantes, France; Hôpital d’Instruction des Armées Bégin, Saint-Mandé, France; Franciscus Gasthuis, Rotterdam, Netherlands; Ministry of Health, and D’Or Institute of Research and Education (IDOR), National Institute of Infectious Disease Evandro Chagas, Oswaldo Cruz Foundation (INI-FIOCRUZ), Rio de Janeiro, Brazil; Centre Hospitalier de Mayotte, Mamoudzou, Mayotte; Hospital Egas Moniz, Lisboa, Portugal; Ospedale Molinette, Torino, Italy; Cork University Hospital, Cork, Ireland; Beacon Hospital, Dublin, Ireland; Monash University, Melbourne, Australia; Nelson Hospital, Nelson, New Zealand; Cleveland Clinic, Weston, United States; Medical University of Vienna, Vienna, Austria; Sechenov University, Moscow, Russian Federation; Clinica Universidad de La Sabana, Chia, Cundinamarca, Colombia; Centre Hospitalier Universitaire de Martinique, Fort-de-France, Saint Martin, France; Centre Hospitalier Régional Metz-Thionville, Metz, France; Emory University Healthcare System, Atlanta, United States; Johns Hopkins, Baltimore, United States; Comissão de Ética, Unidade Local de Saúde de Matosinhos, Porto, Portugal; Presbyterian Hospital Services, Alberquerque, United States; Hospital del Mar, Barcelona, Spain; Reina Sofia University Hospital, Cordoba, Spain; Hospital Espírito Santo de Évora, Évora, Portugal; Hôpital Américain de Paris, Neuilly-sur-Seine, France; Vancouver Island Health, Vancouver, Canada; Centre Hospitalier Métropole Savoie, Chambéry, France; Department of Anesthesiology, Centre hospitalier de l’Université de Montréal, Montreal, United States; University Hospital - Limerick, Limerick, Ireland; Centro Hospitalar e Universitário de Coimbra - Hospital Pediátrico, Coimbra, Portugal; Centre Hospitalier de Béziers, Béziers, France; Hospital São Francisco Xavier, Lisbon, Portugal; Policlinicodi Orsola Universitàdi Bologna, Bologna, Italy; Hospital du Sacre Coeur, Montreal, Canada; Hospital Universitari Sagrat Cor, Barcelona, Spain; Avera McKennan Hospital, Sioux Falls, United States; Centre Hospitalier de Melun, Melun, France; Attapeu Provincial Hospital, Attapeu, Laos; Sunnybrook Health Sciences Centre, Toronto, Canada; Antimicrobial Resistance and Hospital Acquired Infection Department, Public Health England, London, United Kingdom; Hôpital Kremlin-Bicêtre, Le Kremlin-Bicêtre, France; Centre Hospitalier Universitaire Rennes (Hôpital Pontchaillou), Rennes, France; Hôpital Tenon AP-HP, Paris, France; University of Guadalajara Health Sciences Center, Guadalajara, Mexico; Höpital Saint-Antoine AP-HP, Paris, France; National Institutes of Health (NIH), Ministry of Health Malaysia, Setia Alam, Malaysia; Ospedale San Paolo, Milan, Italy; Chonnam National University Hospital, Dong-gu, South Korea; Salavan Provincial Hospital, Salavan, Laos; Pulau Pinang Hospital, Pulau Pinang, Malaysia; Sunway Medical Centre, Selangor, Malaysia; University Hospital Virgen del Rocío / Institute of Biomedicine of Seville, Seville, Spain; University of Utah, Salt Lake City, United States; Children’s Health Ireland, Dublin, Ireland; Roslin Institute, University of Edinburgh, Easter Bush, Edinburgh, United Kingdom; Foothills Medical Centre, Calgary, Canada; Connolly Hospital Blanchardstown, Dublin, Ireland; Carilion Clinic, Roanoke, United States; Centre Hospitalier Départemental Vendée, La Roche-sur-Yon, France; Allegheny General Hospital, Pittsburgh, United States; Fondazione IRCCS Ca, Milan, Italy; University of Chicago, Chicago, United States; Liverpool Clinical Trials Centre, University of Liverpool, Liverpool, United Kingdom; Department of Infectious Disease, Imperial College London, London, United Kingdom; Brantford General Hospital, Brantford, Canada; University of Queensland, Brisbane, Australia; Centre Hospitalier Bretagne Atlantique, Vannes, France; Hôpital Jacques Monod, Le Havre, France; PREPARE and RECOVER EU Consortium, Brussels, Belgium; Tergooi Hospital, Hilversum, Netherlands; Michael Garron Hospital, Toronto, Canada; Hospital de Curry Cabral - Infectious Diseases, Lisbon, Portugal; Mount Sinai Medical Center, Miami, FL, United States; Columbia University, New York, United States; Centre Hospitalier Universitaire de Guadeloupe, Pointe-à-Pitre, Guadeloupe; MRC-University of Glasgow Centre for Virus Research, 464 Bearsden Road, Glasgow, United Kingdom; UH Cleveland Hospital, Cleveland, United States; University Hospital - Waterford, Waterford, Ireland; Saint-Martin, Saint-Martin, Guadeloupe; Department of Statistics, University of Oxford, Oxford, United Kingdom; Centre hospitalier Universitaire de Sherbrooke, Sherbrooke, Canada; Centro Hospitalar de Tondela-Viseu, Viseu, Portugal; Monaldi Hospital, Napoli, Italy; Università Cattolica del Sacro Cuore, Rome, Italy; Department of Infection, Immunity and Cardiovascular Disease, The Florey Institute for Host-Pathogen Interactions, University of Sheffield, Sheffield, United Kingdom; St Christopher’s Hospital for Children, Philadelphia, United States; Piedmont Atlanta Hospital, Atlanta, GA, United States; Hôpital Purpan, Toulouse, France; Hôpital Saint-Louis AP-HP, Paris, France; Centre Hospitalier Emile Roux, Le Puy-en-Velay, France; Hôpital Bel-Air, Thionville, France; Centre Hospitalier Universitaire Toulouse (IUCT), Toulouse, France; Alrijne Hospital, Leiden, Netherlands; Policlinico of Padova, Padova, Italy; Centre Hospitalier Universitaire de Nice (Hôpital Archet), Nice, France; ISARIC Global Support Centre, Oxford, United Kingdom; Universitair Ziekenhuis, Gent, Belgium; INOVA Fairfax Medical Center, Fairfax, VA, United States; Hospital Universitario Dr Negrín, Las Palmas, Spain; Hospital Professor Doutor Fernando Fonseca, Amadora, Portugal; Clinica Las Condes, Santiago, Chile; University Medical Center Groningen, Groningen, Netherlands; Centre Hospitalier Mont-de-Marsan, Mont-de-Marsan, France; Rambam Hospital, Haifa, Israel; Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, United Kingdom; Tallaght University Hospital, Dublin, Ireland; Lions Gate Hospital, Vancouver, Canada; Flevoziekenhuis, Almere, Netherlands; St James’s Hospital, Dublin, Ireland; St Joseph’s Health Center, Sherbrooke, Canada; Centre Hospitalier Universitaire d’Angers, Angers, France; Houston Methodist Hospital, Houston, TX, United States; Oslo University Hospital, Oslo, Norway; Cleveland Clinic, Ohio, OH, United States; Medical College of Wisconsin, WI, United States; Hôpital de la Conception, Marseille, France; Centre Hospitalier de Tourcoing, Tourcoing, France; Centre Hospitalier De Chateaudun, Route De Jallans, Chateaudun, 28200, France; Reinier de Graaf Gasthuis, Delft, Netherlands; Centre Hospitalier Universitaire Rennes (Hôpital Sud), Rennes, France; Tohoku Medical and Pharmaceutical University, Sendai, Japan; Plata Medical Foundation Private Community Hospital, Mar Del, Plata, Argentina; Hospitales Puerta de Hierro, Jalisco, Mexico; Canisius Wilhelmina Ziekenhuis, Nijmenjen, Netherlands; Centre Hospitalier Pierre Oudot, Bourgoin-Jallieu, France; North York General Hospital, Toronto, Canada; Hospital Universiti Sains Malaysia (Mix medical surgical ICU), Kota Bharu, Malaysia; Adult ICU Saiful Anwar Hospital, Malang, Indonesia; University of California San Francisco - Fresno, Fresno, United States; Hospital Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Amadora, Portugal; Centre Hospitalier Techer, Calais, France; Centre Hospitalier Régional et Universitaire de Tours, Tours, France; Liverpool School of Tropical Medicine, Liverpool, United Kingdom; University of Kansas Medical Center, KS, United States; The Montreal Children’s Hospital, Montreal, Canada; Vancouver General Hospital, Vancouver, Canada; Ospedale San Gerardo, Monza, Italy; Hôpital Foch, Suresnes, France; Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada; Bon Secours Hospital, Cork, Ireland; Hospital Verge de la Cinta, Tortosa, Spain; Hospital Escola da Universidade Federal de Pelotas, Pelotas, Brazil; Hôpital Albert Calmette, Lille, France; Saiseikai Senri Hospital, Tochigi, Japan; Manipal Hospital Whitefield, Bangalore, India; Centre Hospitalier de Pau, Pau, France; Hôpital privé d’Antony, Antony, France; São João Hospital Centre, Porto, Portugal; San Pedro de Alcantara Hospital, Cáceres, Spain; Beth Israel Deaconess Medical Center, Boston, United States; Ochsner Clinic Foundation, New Orleans, United States; Department of Internal Medicine No2, Lugansk State Medical University, Lugansk, Ukraine; Klinikum Passau, Germant, Germany; Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates; University of Padua, Padua, Italy; Children’s Hospital of Eastern Ontario, Ottawa, Canada; Mater Misericordiae University, Dublin, Ireland; Centre Hospitalier Henri Duffaut, Avignon, France; The Baruch Padeh Medical Center Poriya, Tiberias, Israel; Lankenau Institute of Medical Research, Wynnewood, United States; The Hospital for Sick Children (SickKids), Toronto, Canada; University Hospital of Tubingen, Tubingen, Germany; CUB-Hôpital Erasme, Anderlecht, Belgium; Permai Hospital, Johor, Malaysia; Schools of Medicine, University of Michigan, Ann Arbor, United States; Hospital Garcia de Orta, Almada, Portugal; Department of Infectious Diseases, Institut Hospital del Mar d’Investigacions Mèdiques (IMIM), Infectious Pathology and Antimicrobial Research Group (IPAR), Hospital del Mar, Universitat Autònoma de Barcelona (UAB), CEXS-Universitat Pompeu Fabra, Barcelona, Spain; Wexford General Hospital, Wexford, Ireland; Baylor Scott, Dallas, United States; Clinica Alemana DeSantiago, Santiago, Chile; Centre Hospitalier du Pays d’Aix, Aix-en-Provence, France; Institute of Microbiology and Infection, University of Birmingham, Birmingham, United Kingdom; Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, United Kingdom; Centre Hospitalier Universitaire Ambroise-Paré, Boulogne-Billancourt, France; Roslin Institute, University of Edinburgh, Easter Bush, Edinburgh, EH25 9RG, United Kingdom; Grigore T, Popa University of Medicine and Pharmacy, Bucharest, Romania; Erasmus Medical Centre, Rotterdam, Netherlands; University Children’s Hospital, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Hospital de Curry Cabral - Internal Medicine, Lisbon, Portugal; Centre Hospitalier Universitaire Toulouse (Larrey), Toulouse, France; Hospital de Amor, Sao Paulo, Brazil; Middlemore Hospital (Canties Manukan Health), Otahuhu, New Zealand; Centre Hospitalier de Soissons, Soissons, France; Red Deer Regional Hospital, Red Deer, Canada; Big Data Institute, Department of Medicine, University of Oxford, Nuffield, Oxford, United Kingdom; McLeod Healthcare System, Florence, United States; Providence Saint John’s Health Centre, Santa Monica, United States; Kluang Hospital, Johor, Malaysia; Institute of Infection, Veterinary and Ecological Sciences, Faculty of Health and Life Sciences, NIHR Health Protection Research Unit, University of Liverpool, Liverpool, United Kingdom; Kintampo Health Research Centre, Kintampo, Ghana; AZ Maria Middelares, Gent, Belgium; Drammen Hospital, Drammen, Norway; Universidad de Las Américas, Quito, Ecuador; Lancaster General Health, PA, United States; PICU Saiful Anwar Hospital, Malang, Indonesia; Nagoya University Hospital, Nagoya, Japan; Long COVID India - Terna Specialty Hospital and Research Centre, Mumbai, India; Centre Hospitalier Le Mans, Le Mans, France; Medical Research Council, University of Glasgow Centre for Virus Research, Glasgow, United Kingdom; Sultanah Bahiyah Hospital, Kedah, Malaysia; Tuanku Ja’afar, Negeri Sembilan, Seremban, Malaysia; University of Alabama at Birmingham Hospital, Birmingham, United States; Hokkaido University Hospital, Hokkaido, Japan; Fukuoka University, Fukuoka, Japan; US NHLBI PETAL Network, Boston, United States; University of California - San Francisco (UCSF), San Francisco, United States; St. Joseph’s Healthcare Hamilton, Hamilton, Canada; Virology Reference Department, National Infection Service, Public Health England, Colindale Avenue, London, United Kingdom; La Paz Hospital, Madrid, Spain; Centre Hospitalier Annecy Genevois, Annecy, France; Hippokration Hospital, Thessaloniki, Greece; RSUP Fatmawati, South Jakarta, Indonesia; Hiroshima University, Hiroshima, Japan; Mie University Hospital, Tsu, Japan; Hospital Aleman, Buenos Aires, Argentina; Oxford University (ISARIC4C), Oxford, United Kingdom; Mills Memorial Hospital, Terrace, Canada; Raja Perempuan Zainab II Hospital, Kelantan, Malaysia; Hospital Nuestra Señora de Gracia, Zaragoza, Spain; Kyungpook National University Hospital, Daegu, South Korea; Consortium IMGEN, Piaseczno, Poland; Tawau Hospital, Sabah, Malaysia; Melaka Hospital, Melaka, Malaysia; Princess Margaret Hospital, Kwai Hung, China; Nationwide Children’s Hospital, Columbus, United States; Washington University in St. Louis, St Louis, MO, United States; Intensive Care Unit, Royal Infirmary Edinburgh, Edinburgh, United Kingdom; University of Oklahoma Health Sciences Center, Oklahoma, United States; Groupe Hospitalier Diaconesses Croix Saint-Simon, Paris, France; Hospital for Tropical Diseases, Ho Chi Minh City, Viet Nam; Unity Health Toronto, Toronto, Canada; McMaster University, Hamilton, Canada; Lahad Datu Hospital, Sabah, Malaysia; Department of Pharmacology, University of Liverpool, Liverpool, United Kingdom; University Hospital of North Norway, Tromso, Norway; Keimyung University Dong San Hospital, Daegu, South Korea; Kimitsu Chuo Hospital, Chiba, Japan; Nuffield Department of Medicine, Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, United Kingdom; Obihiro-Kosei General Hospital, Obihiro, Japan; Marmara University Hospital, Istanbul, Turkey; University Health Network, Toronto, Canada; Apollo Hospitals Chennai, Chennai, India; Hartford HealthCare, Hartford, United States; University Airlangga Hospital (Paediatric), Surabaya, Indonesia; Royal Alexandra Hospital, Edmonton, Canada; Centre Hospitalier Alpes-Leman, Contamine-sur-Arve, France; Centre Hospitalier Universitaire Toulouse (Rangueil), Toulouse, France; Prof Dr R. D. Kandou Central Hospital (Adult), Manado, Indonesia; Université de Paris, Paris, France; Centre Hospitalier Universitaire de Nîmes, Nîmes, France; The Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom; Wellington Regional Hospital, Wellington, New Zealand; University of Alberta Adult ICU, Edmonton, Canada; Centre Hospitalier Universitaire de Montpellier, Montpellier, France; Centre Hospitalier Universitaire de Poitiers, Poitiers, France; Queen Elizabeth Hospital, Sabah, Malaysia; Severance Hospital, Seoul, South Korea; Division of Informatics, Imaging and Data Science, School of Health Sciences, Faculty of Biology, Medicine and Health, Centre for Health Informatics, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom; Hôpital Henri-Mondor, Créteil, France; University Institute of Cardiology and Respirology, Quebec, Canada; Sultanah Nur Zahirah Hospital, Terengganu, Malaysia; Centre Hospitalier Universitaire Gabriel Montpied, Clermont-Ferrand, France; Institute of TB and Lung Diseases, Warsaw, Poland; Waitemata District Health Board, Auckland, New Zealand; Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom; Angeles University Foundation Medical Center, Angeles, Philippines; Malawi-Liverpool Wellcome Trust, Blantyre, Malawi; Saiseikai Utsunomiya Hospital, Tochigi, Japan; University of Florida, Gainesville, United States; Instituto Nacional del Niño San Borja, Lima, Peru; Hospital de Clínicas, Buenos Aires, Argentina; Hospital Emergencia Ate Vitarte, Lima, Peru; Port Macquarie Base Hospital, Port Macquarie, Australia; Klinik und Poliklinik für Innere Medizin II, University Hospital Regensburg, Kiel, Germany; William Osler Health Sciences System - Etobicoke General Hospital, Toronto, Canada; Prof Dr R. D. Kandou Central Hospital (Paediatric), Manado, Indonesia; Hôpital Louis-Mourier, Colombes, France; Hospital Vila Franca de Xira, Lisbon, Portugal; Alberta Children’s Hospital, Calgary, Canada; Department of Intensive Care Medicine, Multidisciplinary Intensive Care Research Organisation (MICRO), St. James’s Hospital, Dublin, Ireland; Centre Hospitalier de Colmar, Colmar, France; Emergency Department. Hospital, Universitario La Paz - IdiPAZ, Madrid, Spain; Kingston Health Sciences Centre, Kingston, Canada; International Islamic University Malaysia Medical Centre (IIUMMC), Pahang, Malaysia; Waikato Hospital, Hamilton, New Zealand; Auckland City Hospital, (DCCM 82), Auckland, New Zealand; Mount Sinai Hospital, Toronto, Canada; London Health Sciences Centre, London, Canada; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Centre Hospitalier de Cahors, Cahors, France; Institute of Genetics and Molecular Medicine, MRC Human Genetics Unit, MRC, University of Edinburgh, Edinburgh, United Kingdom; Centre Hospitalier Universitaire Rouen (Hôpital Charles Nicolle), Rouen, France; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom; Hospital Clinic, Barcelona, Spain; Tengku Ampuan Afzan Hospital, Pahang, Malaysia; Florence Nightingale Faculty of Nursing, Midwifery and Palliative Care, Care for Long Term Conditions Division, King’s College London, London, United Kingdom; Faculty of Medicine, University of British Columbia, Vancouver, Canada; Baystate MC, Springfield, United States; University Hospital Northern British Columbia, Prince George, Canada; St-Pierre University Hospital, Brussels, Belgium; Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Kota Depok, Indonesia; Queen Mary Hospital, Pok Fu Lam, China; Hôpital Pellegrin, Bordeaux, France; Irish Critical Care Critical Clinical Trials Network, Ireland, Dublin, United Kingdom; Siriraj Piyamaharajkarun Hospital (SiPH), Bangkok, Thailand; Oregon Health, Salem, United States; Cleveland Clinic, Abu Dhabi, United Arab Emirates; Division of Infection and Immunity, University College London, London, United Kingdom; Department of Children’s Infectious Diseases, Warsaw, Poland; Dr Sardjito Government Hospital (Paediatric), Yogyakarta, Indonesia; RSUD Pasar Minggu, South Jakarta, Indonesia; Mercy Hospital, Cork, Ireland; Legacy Emanuel Medical Center, Portland, United States; Kyung Pook National University Chilgok Hospital, Daegu, South Korea; Department of Emergency and Critical Care Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan; Instituto do Coração da Universidade de São Paulo (INCOR), São Paulo, Brazil; Misericordia Community Hospital, Edmonton, Canada; Department of Medical Microbiology and Infection Control, Franciscus Gasthuis & amp; Vlietland, Rotterdam, Netherlands; Joseph Brant Hospital, Burlington, Canada; National Heart and Lung Institute, Imperial College London, London, United Kingdom; Tufts Medical Centre, Boston, United States; Mayo Clinic School of Medicine, Arizona, United States; All India Institute of Medical Sciences (AIIMS), Rishikesh, India; Hospital General San Francisco, Quito, Ecuador; Auckland City Hospital (CVICU), Auckland, New Zealand; Hospital Beatriz Ângelo, Loures, Portugal; Niagara Health, Niagara, Canada; Centre Hospitalier de Périgueux, Périgueux, France; University Hospital Ostrava, Ostrava-Poruba, Czech Republic; Humber River Hospital, Toronto, Canada; Maastricht University Medical Centre, Maastricht, Netherlands; North Estonia Medical Centre, Tallin, Estonia; RSUD Dr. Soetomo, Surabaya, Indonesia; Baylor University Medical Centre, Dallas, United States; Apollo Hospitals Chennai, Tamil Nadu, Chennai, India; Ministry of Health, and D’Or Institute of Research and Education (IDOR), National Institute of Infectious Disease Evandro Chagas, Oswaldo Cruz Foundation (INI-FIOCRUZ), Rio de Janeiro, Gaspar Viana Pavilion, Brazil; Network for Improving Critical care Systems and Training, Colombo, Sri Lanka; Clinic of Anesthesiology and Intensive Care, North Estonia Medical Centre, Tallinn, Estonia; Hospital de Abrantes - ICU, Abrantes, Portugal; Hôpital Européen Marseille, Marseille, France; Centre Hospitalier Agen-Nérac, Agen, France; Vall d’Hebron Institute of Research, Barcelona, Spain; University of Manitoba, Manitoba, Canada; Universidad de La Sabana, Chia, Colombia; The Center for Diagnosis, Santo Domingo, Dominican Republic; CHU Carémeau, Nimes, France; Royal Melbourne Hospital, Melbourne, Australia; Hôpital Laënnec - site de Quimper, Quimper, France; Fundación Cardiovascular de Colombia, Floridablanca, Colombia; Hospital Universitari Sant Joan D’Alacant, Alicante, Spain; Department of Pediatrics and Virology, St Mary’s Medical School Bldg, Imperial College London, London, United Kingdom; Department of Infectious Diseases I, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania; Centro Hospitalar Universitário do Algarve, Portimão, Portugal; RSPI Prof Dr Sulianti Saroso, Jakarta, Indonesia; The Heart Hospital Baylor Plano, Plano, United States; Gelre Hospitals, Zutphen, Netherlands; Krankenhaus Barmherzige Br, Regensburg, Germany; Baylor AllSaints Medical Centre, Fort Worth, United States; Sozialmedizinisches Zentrum Sud, Vienna, Austria; Institute of Infection, Veterinary and Ecological Sciences, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, United Kingdom; Centro Hospitalar de Leiria, Leiria, Portugal; Institute of Translational Medicine, University of Liverpool, Liverpool, Merseyside, United Kingdom; Tohoku University, Sendai, Japan; Hyogo Prefectural Kakogawa Medical Center, Hyogo, Japan; Tokyo Metropolitan Tama Medical Center, Tokyo, Japan; Pamela Youde Nethersole Eastern Hospital, Chai Wan, China; Grand River Hospital, Kitchener, Canada; Hospital Sungai Buloh, Ministry of Health, Selangor, Malaysia; Seoul National University Bundang Hospital, Seoul, South Korea; Hospital Universitário Clementino Fraga Filho, Rio de Janeiro, Brazil; Baerum Sykehus, Gjettum, Norway; National Institute for Infectious Diseases Matei Bals, Bucharest, Romania; Carol Davila University of Medicine and Pharmacy, Bucharest, Romania; Division of Structural Biology, The Wellcome Centre for Human Genetics, University of Oxford, Headington, Oxford, OX3 7BN, United Kingdom; Sturgeon Community Hospital, St Albert, Canada; Department of Medicine, University of Cambridge, Cambridgeshire, Cambridge, United Kingdom; University Hospital in Krakow, Krakow, Poland; Centre Hospitalier Universitaire Grenoble-Alpes_FU, Grenoble, France; Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil; Kyoto Medical Centre, Kyoto, Japan; Yokohama City University Medical Center, Yokohama, Japan; Fatmawati Hospital, Jakarta, Indonesia; Virus Reference Department, National Infection Service, Blood Borne Virus Unit, Public Health England, London, United Kingdom; Complexo Hospitalar Dr. Clementino Fraga, João Pessoa city, Brazil; Centre Hospitalier Louis Raffalli, Manosque, France; University of Nebraska Medical Center, Omaha, United States; Division of Critical Care, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa; Clínica Internacional, Lima, Peru; Albury Wodonga Health, Albury, Australia; Hôpital Robert-Debré AP-HP, Paris, France; Dunedin Public Hospital, Dunedin, New Zealand; ADRZ, Amsterdam, Netherlands; Meander Medical Centre, Amersfoort, Netherlands; Adrz, Goes, Netherlands; Noordwest-Ziekenhuisgroep, DenHelder, Netherlands; Grey Nun’s Community Hospital, Edmonton, Canada; Beatrix ziekenhuis, Gorinchem, Netherlands; Royal Columbian Hospital, Vancouver, Canada; Department of Intensive Care, Franciscus Gasthuis, Rotterdam, Netherlands; Queen Elizabeth Hospital, Yau Ma Tei, China; Kyoto Prefectural University of Medicine, Kyoto, Japan; Kouritu Tousei Hospital, Seto City, Japan; MedStar Washington Hospital Centre, WA, United States; Clinica Pasteur National - University of Comahue, Neuquén, Argentina; Sultanah Aminah Hospital, Johor, Malaysia; National Infection Service, Public Health England, London, United Kingdom; Mazankowski Heart Institute, Edmonton, Canada |
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By September 2022, more than 600 million cases of SARS-CoV-2 infection have been reported globally, resulting in over 6.5 million deaths. COVID-19 mortality risk estimators are often, however, developed with small unrepresentative samples and with methodological limitations. It is highly important to develop predictive tools for pulmonary embolism (PE) in COVID-19 patients as one of the most severe preventable complications of COVID-19. Early recognition can help provide life-saving targeted anti-coagulation therapy right at admission. Using a dataset of more than 800,000 COVID-19 patients from an international cohort, we propose a cost-sensitive gradient-boosted machine learning model that predicts occurrence of PE and death at admission. Logistic regression, Cox proportional hazards models, and Shapley values were used to identify key predictors for PE and death. Our prediction model had a test AUROC of 75.9% and 74.2%, and sensitivities of 67.5% and 72.7% for PE and all-cause mortality respectively on a highly diverse and held-out test set. The PE prediction model was also evaluated on patients in UK and Spain separately with test results of 74.5% AUROC, 63.5% sensitivity and 78.9% AUROC, 95.7% sensitivity. Age, sex, region of admission, comorbidities (chronic cardiac and pulmonary disease, dementia, diabetes, hypertension, cancer, obesity, smoking), and symptoms (any, confusion, chest pain, fatigue, headache, fever, muscle or joint pain, shortness of breath) were the most important clinical predictors at admission. Age, overall presence of symptoms, shortness of breath, and hypertension were found to be key predictors for PE using our extreme gradient boosted model. This analysis based on the, until now, largest global dataset for this set of problems can inform hospital prioritisation policy and guide long term clinical research and decision-making for COVID-19 patients globally. Our machine learning model developed from an international cohort can serve to better regulate hospital risk prioritisation of at-risk patients. © The Author(s) 2024. |
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Adult; Aged; Aged, 80 and over; Cohort Studies; COVID-19; Female; Hospitalization; Humans; Machine Learning; Male; Middle Aged; Pulmonary Embolism; Risk Factors; SARS-CoV-2; Spain; United Kingdom; adult; aged; cohort analysis; complication; coronavirus disease 2019; epidemiology; female; hospitalization; human; isolation and purification; lung embolism; machine learning; male; middle aged; mortality; risk factor; Severe acute respiratory syndrome coronavirus 2; Spain; United Kingdom; very elderly |
Institute for Clinical Research; Rhodes Scholarships; NIHR HPRU; Prince Charles Hospital Foundation; NIHR Health Protection Research Unit; Seventh Framework Programme, FP7; Instituto de Salud Carlos III, ISCIII; INSERM; Artificial Intelligence for Pandemics; European Centre for Disease Prevention and Control, ECDC; Groote Schuur Hospital Covid ICU; National Institutes of Health, NIH; South Eastern Norway Health Authority and the Research Council of Norway; Wellcome Trust, WT; COVID-19 Clinical M |
Funding text 1: This work was made possible by the UK Foreign, Commonwealth and Development Office and Wellcome [215091/Z/18/Z, 222410/Z/21/Z, 225288/Z/22/Z and 220757/Z/20/Z]; the Bill & Melinda Gates Foundation [OPP1209135]; the philanthropic support of the donors to the University of Oxford\u2019s COVID-19 Research Response Fund (0009109); CIHR Coronavirus Rapid Research Funding Opportunity OV2 |
Nature Research |
20452322 |
|
39013928 |
Article |
Q1 |
973 |
4401 |
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30 |
Hardiany N.S.; Dewi P.K.K.; Dewi S.; Tejo B.A. |
Hardiany, Novi Silvia (57192910605); Dewi, Putri Krishna Kumara (58795085300); Dewi, Syarifah (57192904541); Tejo, Bimo A. (6506268507) |
57192910605; 58795085300; 57192904541; 6506268507 |
Exploration of neuroprotective effect from Coriandrum sativum L. ethanolic seeds extracts on brain of obese rats |
2024 |
Scientific Reports |
14 |
1 |
603 |
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0 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85181517263&doi=10.1038%2fs41598-024-51221-5&partnerID=40&md5=8cb2d2f97417718e92613268842c4aa6 |
Department of Biochemistry and Molecular Biology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Center of Hypoxia and Oxidative Stress Studies, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Master Program in Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Medical Biochemistry Division, Department of Biomedical Science, Faculty of Medicine, Universitas Pendidikan Ganesha, Bali, 81116, Indonesia; Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, Serdang, 43400, Malaysia |
Hardiany N.S., Department of Biochemistry and Molecular Biology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Center of Hypoxia and Oxidative Stress Studies, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Dewi P.K.K., Master Program in Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Medical Biochemistry Division, Department of Biomedical Science, Faculty of Medicine, Universitas Pendidikan Ganesha, Bali, 81116, Indonesia; Dewi S., Department of Biochemistry and Molecular Biology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Center of Hypoxia and Oxidative Stress Studies, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Tejo B.A., Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, Serdang, 43400, Malaysia |
In this study, the potential neuroprotective ability of coriander seeds (Coriandrum sativum L.) ethanolic extract (CSES) as a neuroprotectant agent in the brains of high-fat diet-induced obese rats was analyzed. The study investigated how CSES impacts oxidative stress markers (i.e., malondialdehyde/MDA, glutathione/GSH and catalase), inflammation marker (i.e., Interleukin-6/IL-6), cellular senescence markers (i.e., senescence-associated β-galactoside/SA-β-Gal activity and p16), brain damage marker (i.e., Neuron-specific Enolase/NSE), and neurogenesis markers (i.e., mature Brain-derived Neurotropic Factor/BDNF, pro-BDNF, and mature/pro-BDNF ratio). Male adult Wistar rats were fed a high-fat diet and given CSES once daily, at 100 mg/kg body weight, for 12 weeks. CSES significantly reduced MDA concentration (p = < 0.001), SA-β-Gal activity (p = 0.010), and increased GSH concentration (p = 0.047) in the brain of obese rats; however, the decrease of IL-6, NSE, and p16 as well as the increase of catalase specific activity and BDNF expression were not significant. Moreover, the mature/pro-BDNF ratio was significantly higher in the brains of non-obese rats, both given the control diet and the high-fat diet compared to the control. Our results suggest that obese rats benefited from consuming CSES, showing improved oxidative stress levels, reduced cellular senescence and increased endogenous antioxidants, making CSES a potential neuroprotective agent. © 2024, The Author(s). |
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Animals; Brain; Brain-Derived Neurotrophic Factor; Catalase; Coriandrum; Ethanol; Glutathione; Interleukin-6; Male; Neuroprotective Agents; Obesity; Rats; Rats, Wistar; Seeds; alcohol; brain derived neurotrophic factor; catalase; glutathione; interleukin 6; neuroprotective agent; animal; brain; Coriandrum; male; obesity; plant seed; rat; Wistar rat |
HIBAH PUTI Universitas Indonesia 2023, (NKB-392/UN2.RST/HKP.05.00/2023) |
This research received funding from HIBAH PUTI Universitas Indonesia 2023 (grant number: NKB-392/UN2.RST/HKP.05.00/2023). |
Nature Research |
20452322 |
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38182767 |
Article |
Q1 |
973 |
4401 |
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44 |
Sardjan J.; Lesmana C.R.A.; Rusdi L.; Kurniawan J.; Yunihastuti E.; Susilo A.; Gani R.A. |
Sardjan, Jordan (59204197000); Lesmana, Cosmas Rinaldi Adithya (8977683000); Rusdi, Lusiani (57193236387); Kurniawan, Juferdy (57193251655); Yunihastuti, Evy (57221273925); Susilo, Adityo (57217867079); Gani, Rino Alvani (23495930300) |
59204197000; 8977683000; 57193236387; 57193251655; 57221273925; 57217867079; 23495930300 |
Correlation between controlled attenuation parameter values with SYNTAX score in patients with significant coronary artery disease |
2024 |
Scientific Reports |
14 |
1 |
15382 |
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0 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85197514199&doi=10.1038%2fs41598-024-63792-4&partnerID=40&md5=58e88db82554e800e7752f73625a7492 |
Department of Internal Medicine, Dr. Cipto Mangunkusumo National General Hospital, Medical Faculty University of Indonesia, Jakarta, Indonesia; Division of Hepatobiliary, Department of Internal Medicine, Dr. Cipto Mangunkusumo National General Hospital, Medical Faculty University of Indonesia, Jakarta, Indonesia; Division of Cardiology, Department of Internal Medicine, Dr. Cipto Mangunkusumo National General Hospital, Medical Faculty University of Indonesia, Jakarta, Indonesia; Division of Allergy and Immunology, Department of Internal Medicine, Dr. Cipto Mangunkusumo National General, Hospital, Medical Faculty University of Indonesia, Jakarta, Indonesia; Division of Tropical and Infectious Disease, Department of Internal Medicine, Dr. Cipto Mangunkusumo National General Hospital, Medical Faculty University of Indonesia, Jakarta, Indonesia |
Sardjan J., Department of Internal Medicine, Dr. Cipto Mangunkusumo National General Hospital, Medical Faculty University of Indonesia, Jakarta, Indonesia; Lesmana C.R.A., Division of Hepatobiliary, Department of Internal Medicine, Dr. Cipto Mangunkusumo National General Hospital, Medical Faculty University of Indonesia, Jakarta, Indonesia; Rusdi L., Division of Cardiology, Department of Internal Medicine, Dr. Cipto Mangunkusumo National General Hospital, Medical Faculty University of Indonesia, Jakarta, Indonesia; Kurniawan J., Division of Hepatobiliary, Department of Internal Medicine, Dr. Cipto Mangunkusumo National General Hospital, Medical Faculty University of Indonesia, Jakarta, Indonesia; Yunihastuti E., Division of Allergy and Immunology, Department of Internal Medicine, Dr. Cipto Mangunkusumo National General, Hospital, Medical Faculty University of Indonesia, Jakarta, Indonesia; Susilo A., Division of Tropical and Infectious Disease, Department of Internal Medicine, Dr. Cipto Mangunkusumo National General Hospital, Medical Faculty University of Indonesia, Jakarta, Indonesia; Gani R.A., Division of Hepatobiliary, Department of Internal Medicine, Dr. Cipto Mangunkusumo National General Hospital, Medical Faculty University of Indonesia, Jakarta, Indonesia |
Non-alcoholic fatty liver disease (NAFLD) is an emerging cause of chronic liver disease, with coronary artery disease (CAD) as the main cause of death in NAFLD patients. However, correlation between the severity of liver steatosis and coronary atherosclerosis is yet to be understood. Here we aim to explore the correlation between controlled attenuation parameter (CAP) values and SYNTAX (Synergy Between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery) score in adult patients with significant CAD, defined as ≥ 50% stenosis of the left main coronary artery, or ≥ 70% stenosis of the other major coronary arteries. A cross-sectional study was conducted on 124 adult patients with significant CAD who underwent coronary angiography. Transient elastography with CAP was used to assess liver steatosis severity, resulting in a mean CAP value of 256.5 ± 47.3 dB/m, with 52.5% subjects had significant steatosis (CAP value of ≥ 248 dB/m). Median SYNTAX score was 22. A statistically significant correlation was observed between CAP value and SYNTAX score (r = 0.245, p < 0.0001). The correlation was more pronounced in patients with prior history of PCI (r = 0.389, p = 0.037). Patients with high-risk SYNTAX score (> 32) had the highest CAP value (285.4 ± 42.6 dB/m), and it was significantly higher than those with low-risk SYNTAX score (0–22), with a mean difference of 38.76 dB/m (p = 0.006). Patients with significant liver steatosis should undergo periodic CAD assessment and lifestyle modification, especially those with severe liver steatosis. © The Author(s) 2024. |
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Aged; Coronary Angiography; Coronary Artery Disease; Cross-Sectional Studies; Elasticity Imaging Techniques; Female; Humans; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Percutaneous Coronary Intervention; Severity of Illness Index; aged; complication; coronary angiography; coronary artery disease; cross-sectional study; diagnostic imaging; elastography; female; human; male; middle aged; nonalcoholic fatty liver; pathology; percutaneous coronary intervention; severity of illness index |
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Nature Research |
20452322 |
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38965252 |
Article |
Q1 |
973 |
4401 |
|
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63 |
Lee K.H.; Jiamsakul A.; Kiertiburanakul S.; Borse R.; Khol V.; Yunihastuti E.; Azwa I.; Ketut Agus Somia I.; Chaiwarith R.; Pham T.N.; Khusuwan S.; Do C.D.; Kumarasamy N.; Gani Y.; Ditangco R.; Ng O.T.; Pujari S.; Lee M.P.; Avihingsanon A.; Chen H.-P.; Zhang F.; Tanuma J.; Ross J.; Choi J.Y. |
Lee, Ki Hyun (57223989176); Jiamsakul, Awachana (55285745500); Kiertiburanakul, Sasisopin (6506539792); Borse, Rohidas (59198920300); Khol, Vohith (57188842644); Yunihastuti, Evy (57221273925); Azwa, Iskandar (55553159100); Ketut Agus Somia, I. (58145407800); Chaiwarith, Romanee (13806165200); Pham, Thach Ngoc (57213330022); Khusuwan, Suwimon (56166613100); Do, Cuong Duy (56658396600); Kumarasamy, Nagalingeswaran (7003549856); Gani, Yasmin (57188842533); Ditangco, Rossana (55406840800); Ng, Oon |
57223989176; 55285745500; 6506539792; 59198920300; 57188842644; 57221273925; 55553159100; 58145407800; 13806165200; 57213330022; 56166613100; 56658396600; 7003549856; 57188842533; 55406840800; 59091740100; 57205894660; 59164277600; 57196347321; 59198669900; 55503803800; 57208428839; 57193109926; 59198670000 |
Risk factors for toxoplasmosis in people living with HIV in the Asia-Pacific region |
2024 |
PLoS ONE |
19 |
45480 |
e0306245 |
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0 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85197292104&doi=10.1371%2fjournal.pone.0306245&partnerID=40&md5=d1e3bea7f73eec983d6cb41db62cc2ae |
Department of Internal Medicine, AIDS Research Institute, Yonsei University College of Medicine, Seoul, South Korea; The Kirby Institute, UNSW Sydney, Kensington, NSW, Australia; Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; BJ Government Medical College, Sassoon General Hospital, Pune, India; National Center for HIV/AIDS, Dermatology & STDs, Phnom Penh, Cambodia; Faculty of Medicine Universitas Indonesia - Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Infectious Diseases Unit, Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia; Faculty of Medicine, Udayana University, Prof. Dr. I.G.N.G. Ngoerah Hospital, Bali, Indonesia; Division of Infectious Diseases and Tropical Medicine, Department of Medicine, Faculty of Medicine, Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand; National Hospital for Tropical Diseases, Hanoi, Viet Nam; Chiangrai Prachanukroh Hospital, Chiang Rai, Thailand; Bach Mai Hospital, Hanoi, Viet Nam; CART CRS, Voluntary Health Services, Chennai, India; Hospital Sungai Buloh, Sungai Buloh, Malaysia; Research Institute for Tropical Medicine, Muntinlupa City, Philippines; National Centre for Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore; Institute of Infectious Diseases, Pune, India; Queen Elizabeth Hospital, Yau Ma Tei, Hong Kong; HIV-NAT/ Thai Red Cross AIDS Research Centre, Center of Excellence in Tuberculosis, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; Taipei Veterans General Hospital, Taipei, Taiwan; Beijing Ditan Hospital, Capital Medical University, Beijing, China; National Center for Global Health and Medicine, Tokyo, Japan; TREAT Asia, amfAR - The Foundation for AIDS Research, Bangkok, Thailand |
Lee K.H., Department of Internal Medicine, AIDS Research Institute, Yonsei University College of Medicine, Seoul, South Korea; Jiamsakul A., The Kirby Institute, UNSW Sydney, Kensington, NSW, Australia; Kiertiburanakul S., Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; Borse R., BJ Government Medical College, Sassoon General Hospital, Pune, India; Khol V., National Center for HIV/AIDS, Dermatology & STDs, Phnom Penh, Cambodia; Yunihastuti E., Faculty of Medicine Universitas Indonesia - Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Azwa I., Infectious Diseases Unit, Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia; Ketut Agus Somia I., Faculty of Medicine, Udayana University, Prof. Dr. I.G.N.G. Ngoerah Hospital, Bali, Indonesia; Chaiwarith R., Division of Infectious Diseases and Tropical Medicine, Department of Medicine, Faculty of Medicine, Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand; Pham T.N., National Hospital for Tropical Diseases, Hanoi, Viet Nam; Khusuwan S., Chiangrai Prachanukroh Hospital, Chiang Rai, Thailand; Do C.D., Bach Mai Hospital, Hanoi, Viet Nam; Kumarasamy N., CART CRS, Voluntary Health Services, Chennai, India; Gani Y., Hospital Sungai Buloh, Sungai Buloh, Malaysia; Ditangco R., Research Institute for Tropical Medicine, Muntinlupa City, Philippines; Ng O.T., National Centre for Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore; Pujari S., Institute of Infectious Diseases, Pune, India; Lee M.P., Queen Elizabeth Hospital, Yau Ma Tei, Hong Kong; Avihingsanon A., HIV-NAT/ Thai Red Cross AIDS Research Centre, Center of Excellence in Tuberculosis, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; Chen H.-P., Taipei Veterans General Hospital, Taipei, Taiwan; Zhang F., Beijing Ditan Hospital, Capital Medical University, Beijing, China; Tanuma J., National Center for Global Health and Medicine, Tokyo, Japan; Ross J., TREAT Asia, amfAR - The Foundation for AIDS Research, Bangkok, Thailand; Choi J.Y., Department of Internal Medicine, AIDS Research Institute, Yonsei University College of Medicine, Seoul, South Korea |
Introduction Toxoplasma gondii can cause symptomatic toxoplasmosis in immunodeficient hosts, including in people living with human immunodeficiency virus (PLWH), mainly because of the reactivation of latent infection. We assessed the prevalence of toxoplasmosis and its associated risk factors in PLWH in the Asia-Pacific region using data from the TREAT Asia Human Immunodeficiency Virus (HIV) Observational Database (TAHOD) of the International Epidemiology Databases to Evaluate AIDS (IeDEA) Asia-Pacific. Methods This study included both retrospective and prospective cases of toxoplasmosis reported between 1997 and 2020. A matched case-control method was employed, where PLWH diagnosed with toxoplasmosis (cases) were each matched to two PLWH without a toxoplasmosis diagnosis (controls) from the same site. Sites without toxoplasmosis were excluded. Risk factors for toxoplasmosis were analyzed using conditional logistic regression. Results A total of 269/9576 (2.8%) PLWH were diagnosed with toxoplasmosis in 19 TAHOD sites. Of these, 227 (84%) were reported retrospectively and 42 (16%) were prospective diagnoses after cohort enrollment. At the time of toxoplasmosis diagnosis, the median age was 33 years (interquartile range 28–38), and 80% participants were male, 75% were not on antiretroviral therapy (ART). Excluding 63 out of 269 people without CD4 values, 192 (93.2%) had CD4 ≤200 cells/μL and 162 (78.6%) had CD4 ≤100 cells/μL. By employing 538 matched controls, we found that factors associated with toxoplasmosis included abstaining from ART (odds ratio [OR] 3.62, 95% CI 1.81–7.24), in comparison to receiving nucleoside reverse transcriptase inhibitors plus non-nucleoside reverse transcriptase inhibitors, HIV exposure through injection drug use (OR 2.27, 95% CI 1.15–4.47) as opposed to engaging in heterosexual intercourse and testing positive for hepatitis B virus surface antigen (OR 3.19, 95% CI 1.41–7.21). Toxoplasmosis was less likely with increasing CD4 counts (51–100 cells/μL: OR 0.41, 95% CI 0.18–0.96; 101–200 cells/μL: OR 0.14, 95% CI 0.06–0.34; >200 cells/μL: OR 0.02, 95% CI 0.01–0.06), when compared to CD4 ≤50 cells/μL. Moreover, the use of prophylactic cotrimoxazole was not associated with toxoplasmosis. Conclusions Symptomatic toxoplasmosis is rare but still occurs in PLWH in the Asia-Pacific region, especially in the context of delayed diagnosis, causing advanced HIV disease. Immune reconstitution through early diagnosis and ART administration remains a priority in Asian PLWH. Copyright: © 2024 Lee et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
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Adult; Asia; Case-Control Studies; Female; HIV Infections; Humans; Male; Middle Aged; Prevalence; Prospective Studies; Retrospective Studies; Risk Factors; Toxoplasma; Toxoplasmosis; CD4 antigen; cotrimoxazole; hepatitis B surface antigen; nonnucleoside reverse transcriptase inhibitor; adult; antiretroviral therapy; Article; Asian; CD4 lymphocyte count; controlled study; delayed diagnosis; human; Human immunodeficiency virus infected patient; Human immunodeficiency virus infection; immune deficiency; major clinical study; male; prevalence; risk factor; sexual intercourse; toxoplasmosis; virus load; Asia; case control study; complication; epidemiology; female; middle aged; prospective study; retrospective study; Toxoplasma; toxoplasmosis |
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Public Library of Science |
19326203 |
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38950027 |
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Karyanti M.R.; Uiterwaal C.S.P.M.; Hadinegoro S.R.; Widyahening I.S.; Saldi S.R.F.; Heesterbeek J.A.P.H.; Hoes A.W.; Bruijning-Verhagen P. |
Karyanti, Mulya Rahma (56290680800); Uiterwaal, Cuno S P M (59148037600); Hadinegoro, Sri Rezeki (56893685800); Widyahening, Indah Suci (54893154400); Saldi, Siti Rizny F (55201904000); Heesterbeek, J A P Hans (59134733500); Hoes, Arno W. (35370614300); Bruijning-Verhagen, Patricia (55175644800) |
56290680800; 59148037600; 56893685800; 54893154400; 55201904000; 59134733500; 35370614300; 55175644800 |
The Value of Warning Signs From the WHO 2009 Dengue Classification in Detecting Severe Dengue in Children |
2024 |
The Pediatric infectious disease journal |
43 |
7 |
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630 |
634 |
4 |
0 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85196767536&doi=10.1097%2fINF.0000000000004326&partnerID=40&md5=04c0ef35f4c83ec1bb4da39449b609c4 |
From the Department of Child Health, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht and Utrecht University, Utrecht, Netherlands; Department of Community Medicine, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Clinical Epidemiology and Evidence-Based Medicine Unit, Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Population Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands |
Karyanti M.R., From the Department of Child Health, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht and Utrecht University, Utrecht, Netherlands; Uiterwaal C.S.P.M., Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht and Utrecht University, Utrecht, Netherlands; Hadinegoro S.R., From the Department of Child Health, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Widyahening I.S., Department of Community Medicine, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Saldi S.R.F., Clinical Epidemiology and Evidence-Based Medicine Unit, Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Heesterbeek J.A.P.H., Department of Population Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands; Hoes A.W., Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht and Utrecht University, Utrecht, Netherlands; Bruijning-Verhagen P., Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht and Utrecht University, Utrecht, Netherlands |
BACKGROUND: World Health Organization proposed 7 warning signs to identify the risk of severe dengue in 2009. This study aimed to evaluate the value of these warning signs in detecting severe dengue in children. MATERIAL AND METHODS: A cross-sectional study was conducted utilizing data of children with clinical dengue infection obtained from medical records between January 2009 and December 2018 in Jakarta. Children with confirmed dengue were analyzed and stratified into 3 age groups: infants less than 1 year old, children 1-14 years and adolescents 15-18 years of age. Positive predictive value, negative predictive value (NPV), sensitivity and specificity of each warning sign present or absent on admission in detecting severe dengue were computed. RESULTS: Six hundred ninety-nine children with clinical dengue infection were enrolled, among whom 614 (87.8%) had confirmed dengue infection, either by antigen or antibody serological tests. Severe dengue occurred in 211/614 (34.4%) cases. In infants, important warning signs on admission to detect or exclude severe dengue were liver enlargement (NPV 80.8%) and clinical fluid accumulation (NPV 75%). In children and adolescents, warning sign with highest NPV (in children 76.6% and in adolescents 91.9%) was increase in hematocrit concurrent with a rapid decrease in platelet count. Other warning signs with high NPV values in children were abdominal pain (72%), vomiting (70%), clinical fluid accumulation (69.3%), and in adolescents' abdominal pain (80.7%), vomiting (75.7%), clinical fluid accumulation (82.7%). NPVs increase with more than 1 warning sign in all age groups. CONCLUSION: In infants, liver enlargement or clinical fluid accumulation are important warning signs for severe dengue, when both are absent, severe dengue is unlikely. In older children and adolescents, an increase in hematocrit with the concurrent rapid decrease in platelet count is most discriminative; followed by the absence of abdominal pain, vomiting or fluid accumulation are unlikely severe dengue. Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc. |
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Adolescent; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Infant; Male; Sensitivity and Specificity; Severe Dengue; World Health Organization; adolescent; child; cross-sectional study; diagnosis; female; human; infant; male; preschool child; sensitivity and specificity; severe dengue; World Health Organization |
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Strahan A.G.; Davies O.M.T.; Fernández L.T.; Gaylord I.W.I.; Mekonnen Y.G.; Grijsen M.L.; Ollague J.E.; Sabushimike D.; Silveira L.P.; Maurer T.; Dodiuk-Gad R.P.; Singal A.; Lim H.W.; Bhose A.; Lubov J.E.; Jain S.; Zehtab M.; Allison T.; Guerin M.; Enbiale W.; Rehmus W.; Wanat K.A.; Claire Fuller L.; Bailey E.; Freeman E.E. |
Strahan, Alexis G (57763232500); Davies, Olivia M. T (57209472851); Fernández, Lucía T (57221752194); Gaylord, Inena Wa Inena (58137068300); Mekonnen, Yared Getachew (59226922500); Grijsen, Marlous L (25225113700); Ollague, Jose E (59016732900); Sabushimike, Doriane (57218930014); Silveira, Luisa Polo (59199659000); Maurer, Toby (7005701737); Dodiuk-Gad, Roni P (6506007271); Singal, Archana (7006832180); Lim, Henry W (7403095264); Bhose, Arpita (59226908800); Lubov, Janet E (57221373729); Jain, |
57763232500; 57209472851; 57221752194; 58137068300; 59226922500; 25225113700; 59016732900; 57218930014; 59199659000; 7005701737; 6506007271; 7006832180; 7403095264; 59226908800; 57221373729; 59202621600; 59160460400; 59226935300; 59226896300; 55430060500; 56633596500; 16679948300; 58942297900; 52163108700; 18436388200 |
Expanding global health dermatology leadership: launching the GLODERM international mentorship programme |
2024 |
British Journal of Dermatology |
191 |
2 |
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286 |
289 |
3 |
0 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85199125958&doi=10.1093%2fbjd%2fljae164&partnerID=40&md5=4bf84ad17877002f75df089919964fbe |
Department of Dermatology, Massachusetts General Hospital, Boston, MA, United States; Mercer University School of Medicine, Savannah, GA, United States; Harvard Medical School Combined Dermatology Program, Boston, MA, United States; Department of Dermatology, Hospital Universitario José E. Gonzalez, Monterrey, Mexico; Department of Dermatology, Hopital du Cinquantenaire de Kisangani, Kisangani, Democratic Republic Congo; Department of Dermatology, College of Health and Medical Science, Haramaya University, Harar, Ethiopia; Oxford University Clinical Research Unit Indonesia, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom; Hospital General Guasmo Sur, Guayaquil, Ecuador; Hopital Militaire de Kamenge, Bujumbura, Burundi; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, United States; Department of Dermatology, Indiana University School of Medicine, Indianapolis, IN, United States; Department of Dermatology, Emek Medical Center, Afula, Israel; Division of Dermatology, Department of Medicine, University of Toronto, Toronto, ON, Canada; Department of Dermatology, Bruce Rappaport Faculty of Medicine, Technion Institute of Technology, Haifa, Israel; Department of Dermatology, University College of Medical Sciences & G.T.B. Hospital, Dilshad Garden, Delhi, India; Department of Dermatology Henry Ford Health, Detroit, MI, United States; International League of Dermatological Societies, London, United Kingdom; Wright State University Boonshoft School of Medicine, Dayton, OH, United States; Louisiana State University Health Sciences Center New Orleans, New Orleans, LA, United States; CeraVe L Oréal Group, New York, NY, United States; Department of Dermatology, College of Health Sciences and Medicine, Bahir Dar University, Bahir Dar, Ethiopia; Department of Dermatology, Amsterdam Institute for Infection and Immunity (AII), Academic Medical Centre, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands; Division of Dermatology, BC Children s Hospital, University of British Columbia, Vancouver, BC, Canada; Department of Dermatology and Pathology, Medical College of Wisconsin, Milwaukee, WI, United States; London Bridge Hospital, London, United Kingdom; International Foundation for Dermatology, London, United Kingdom; Department of Dermatology, Stanford University School of Medicine, Redwood City, CA, United States; Medical Practice Evaluation Foundation, Massachusetts General Hospital, Boston, MA, United States |
Strahan A.G., Department of Dermatology, Massachusetts General Hospital, Boston, MA, United States, Mercer University School of Medicine, Savannah, GA, United States; Davies O.M.T., Department of Dermatology, Massachusetts General Hospital, Boston, MA, United States, Harvard Medical School Combined Dermatology Program, Boston, MA, United States; Fernández L.T., Department of Dermatology, Hospital Universitario José E. Gonzalez, Monterrey, Mexico; Gaylord I.W.I., Department of Dermatology, Hopital du Cinquantenaire de Kisangani, Kisangani, Democratic Republic Congo; Mekonnen Y.G., Department of Dermatology, College of Health and Medical Science, Haramaya University, Harar, Ethiopia; Grijsen M.L., Oxford University Clinical Research Unit Indonesia, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom; Ollague J.E., Hospital General Guasmo Sur, Guayaquil, Ecuador; Sabushimike D., Hopital Militaire de Kamenge, Bujumbura, Burundi; Silveira L.P., Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, United States; Maurer T., Department of Dermatology, Indiana University School of Medicine, Indianapolis, IN, United States; Dodiuk-Gad R.P., Department of Dermatology, Emek Medical Center, Afula, Israel, Division of Dermatology, Department of Medicine, University of Toronto, Toronto, ON, Canada, Department of Dermatology, Bruce Rappaport Faculty of Medicine, Technion Institute of Technology, Haifa, Israel; Singal A., Department of Dermatology, University College of Medical Sciences & G.T.B. Hospital, Dilshad Garden, Delhi, India; Lim H.W., Department of Dermatology Henry Ford Health, Detroit, MI, United States, International League of Dermatological Societies, London, United Kingdom; Bhose A., International League of Dermatological Societies, London, United Kingdom; Lubov J.E., Department of Dermatology, Massachusetts General Hospital, Boston, MA, United States, Wright State University Boonshoft School of Medicine, Dayton, OH, United States; Jain S., Louisiana State University Health Sciences Center New Orleans, New Orleans, LA, United States; Zehtab M., Department of Dermatology, Massachusetts General Hospital, Boston, MA, United States; Allison T., CeraVe L Oréal Group, New York, NY, United States; Guerin M., CeraVe L Oréal Group, New York, NY, United States; Enbiale W., Department of Dermatology, College of Health Sciences and Medicine, Bahir Dar University, Bahir Dar, Ethiopia, Department of Dermatology, Amsterdam Institute for Infection and Immunity (AII), Academic Medical Centre, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands; Rehmus W., Division of Dermatology, BC Children s Hospital, University of British Columbia, Vancouver, BC, Canada; Wanat K.A., Department of Dermatology and Pathology, Medical College of Wisconsin, Milwaukee, WI, United States; Claire Fuller L., London Bridge Hospital, London, United Kingdom, International Foundation for Dermatology, London, United Kingdom; Bailey E., Department of Dermatology, Stanford University School of Medicine, Redwood City, CA, United States; Freeman E.E., Department of Dermatology, Massachusetts General Hospital, Boston, MA, United States, International Foundation for Dermatology, London, United Kingdom, Medical Practice Evaluation Foundation, Massachusetts General Hospital, Boston, MA, United States |
[No abstract available] |
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Dermatology; Global Health; Humans; International Cooperation; Leadership; Mentors; dermatology; education; global health; human; international cooperation; leadership; mentor; organization and management |
International League of Dermatological Societies; ILDS; CeraVe, Care for All; International Foundation of Dermatology; Melanie Vidal; Jehireh PerazaWilliams; Gene Colon |
Funding text 1: We would like to thank Emma van Rooijen [International League of Dermatological Societies (ILDS)], Becca Garratt (ILDS), Lars French (ILDS Immediate Past President), Melanie Vidal (CeraVe), Gene Colon (CeraVe) and Jehireh PerazaWilliams (CeraVe) for their support in the development of the GLODERM Mentorship Programme. GLODERM is an official programme of the International Foundation |
Oxford University Press |
70963 |
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38666309 |
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